Biochemical detection of pediatric eosinophilic esophagitis using high wavenumber Raman endoscopy and stimulated Raman microscopy by Ezekiel J. Haugen, Andrea K. Locke, Lily H. Dao, Alec B. Walter, Pratheepa K. Rasiah, Justin S. Baba, Matthew A. Buendia, Hernán Correa, Girish Hiremath, Anita Mahadevan-Jansen

“…These findings were verified by ex vivo analysis of esophageal biopsies with stimulated Raman scattering (SRS) microscopy, Raman microspectroscopy, and histochemical staining, which revealed significant decreases in epithelial carbohydrate content and increases in nucleic acid content in active EoE. …”
Get full text

Addition to the summary of cryptogam vascular and gymnosperms plants: “Flora of the Lower Volga Region” (based on materials of the herbarium of SSU (SARAT)) by Boldyrev, Vladimir Alexandrovich, Nyuschenko, Ekaterina Alexandrovna, Stepanov, Michail Vladimirovich

“…The herbarium of the SSU (SARAT) registered 33 species of higher spore-bearing vascular plants: Lycopodiophyta – four, Equisetophyta – six, Polypodiophyta – 19 and Pinophyta – four out of 41 species indicated in the literature for the Lower Volga region. The fund currently contains 1539 herbarium sheets related to the studied devisions the collections of which were carried out from 1902 to 2017. …”
Get full text

Trends, Cycles and Seasonal Variations of Ukrainian Gross Domestic Product by Debesh Bhowmik

“…The article attempts to study trends, seasonal variations and cyclical fluctuations of Ukraine’s quarterly GDP at current prices. The period of the study is from the first quarter of 2010 to the first quarter of 2020. …”
Get full text

Observation of bi-directional global Alfvén eigenmodes in the MAST-U tokamak by M.B. Dreval, H.J.C. Oliver, S.E. Sharapov, J.F. Rivero-Rodriguez, M. Fitzgerald, C. Michael, R. Ochoukov, L. Velarde, M. Cecconello, D. Ryan, the MAST-U Team

“…In low plasma current ( I _p ) discharges, we observe only GAEs propagating counter to the plasma current and the beam direction. …”
Get full text

Water- and frost-resistance of crushed stone mastic asphalt concrete prepared on sevilen-modified bitumen by V. V. Yadykina, S. N. Navolokina, A. M. Gridchin

“…Introduction. Currently, increasing the durability of road asphalt concrete pavements is one of the urgent issues, the solution of which provides a significant economic effect achieved by increasing the turnaround time, as well as the overall service life of highways. …”
Get full text

Assessing the Quality of Concrete Tunnel Lining Exposed to Tunnel Fire through Residual Compressive Strength by Husen Alhawat, R. Hamid, Shahrizan Baharom, M. R. Azmi, A. B. M. A. Kaish

“…Another concrete tunnel lining segment was constructed using concrete containing silica fume normally used in the current construction, coded as SPC concrete. …”
Get full text

The impacts of perceived overqualification on employee performance: A case of chefs by Gökhan ONAT, Duygu Eren

“…As a result of the analysis made with the data collected, it was found that perceived overqualification negatively and significantly affects employee performance. In this context, as a result of this study, it can be said that employee performance may increase or decrease if the overqualification observed in chefs increases or decreases. …”
Get full text

Computational markers show specific deficits for dyslexia and ADHD in complex learning settings by Yafit Gabay, Lana Jacob, Atil Mansour, Uri Hertz

“…Abstract The current study examined how individuals with neurodevelopmental disorders navigate the complexities of learning within multidimensional environments marked by uncertain dimension values and without explicit guidance. …”
Get full text

Advancing the therapeutic effectiveness of paclitaxel in chronic lymphocytic leukemia through the simultaneous inhibition of NOTCH1 and SF3B1 by Shiva Abolhasani, Armin Mahmoud salehi Khesht, Atefeh Khodakarami, Ali Masjedi, Bentolhoda Rashidi, Sepideh Izadi, Fatemeh Karimian Noukabadi, Vahid Karpisheh, Khatereh Torabi Poudeh, Pooya Jalali, Zahra Salehi, Rafieh Bagherifar, Seyyed Sina Hejazian, AliAkbar Movassaghpour, Abbas Ali Hosseinpour Feizi, Farhad Jadidi

“…Overexpression of the splicing factor 3b subunit 1 (SF3B1) and neurogenic locus notch homolog protein 1 (NOTCH1) factors is typically found in chronic lymphocytic leukemia (CLL), leading to the development of chemotherapy resistance. Objective The current investigation aims to evaluate the chemosensitivity of CLL cells by blocking NOTCH1 and SF3B1 using chitosan lactate (CL) nanoparticles (NPs). …”
Get full text

Monitoring ground temperature and deformation of the cast-in-place footings in permafrost regions on the Qinghai‒Tibet Plateau by Chao-Wei Wang, Yan-Hui You, Bin Yao, Bin Liu, Pei-Heng Guo, Lei Guo, Xin-Bin Wang, Qi-Hao Yu

“…The long-term stability of the cast-in-place footings in permafrost regions has received much attention due to its climate sensitivity. The current research lacks long-term data validation, especially in the context of climate change. …”
Get full text

Explorative Study of Modulatory Effects of Notochordal Cell‐Derived Extracellular Vesicles on the IL‐1β‐Induced Catabolic Cascade in Nucleus Pulposus Cell Pellets and Explants... by J. C. vanMaanen, F. C. Bach, J. W. Snuggs, K. Ito, M. H. M. Wauben, C. L. Le Maitre, M. A. Tryfonidou

“…Modification of the CCL2 secretion seemed to be context dependent in the human explants: where EVs treatment stimulated CCL2 secretion but in the presence of IL‐1β this effect was counteracted. …”
Get full text

Effects of ibrutinib and venetoclax on the expression of immune checkpoint molecules in leukemic blasts of patients with acute lymphoblastic leukemia by Armin Dozandeh-Jouybari, Fatemeh Mousavi-Mirkalaei, Saeid Taghiloo, Hossein Karami, Mohammad Naderisorki, Ehsan Zaboli, Mohammad Eslami-Jouybari, Tohid Kazemi, Hossein Asgarian-Omran

“…By elucidating the precise underlying mechanisms, these drugs could emerge as promising therapeutic options, particularly in the context of combination therapy for ALL.…”
Get full text

Anti-tumor activity of a novel compound-CDF is mediated by regulating miR-21, miR-200, and PTEN in pancreatic cancer. by Bin Bao, Shadan Ali, Dejuan Kong, Sanila H Sarkar, Zhiwei Wang, Sanjeev Banerjee, Amro Aboukameel, Subhash Padhye, Philip A Philip, Fazlul H Sarkar

“…<h4>Methodology/principal findings</h4>In the current study we showed, for the first time, that CDF could significantly inhibit the sphere-forming ability (pancreatospheres) of PC cells consistent with increased disintegration of pancreatospheres, which was associated with attenuation of CSC markers (CD44 and EpCAM), especially in gemcitabine-resistant (MIAPaCa-2) PC cells containing high proportion of CSCs consistent with increased miR-21 and decreased miR-200. …”
Get full text

Cohort profile: the PHARMO Perinatal Research Network (PPRN) in the Netherlands: a population-based mother–child linked cohort by E. Houben, L. Broeders, E.A.P. Steegers, R.M.C. Herings

“…Additionally, mother–child linkage is currently available for a quarter of these pregnancies (‘Child Cohort’). …”
Get full text

Potential impacts of plant pests and diseases on trees and forests in the United Kingdom by Daniel P. Bebber, Ilya M. D. Maclean, Jonathan R. Mosedale, Benjamin D. Youngman

“…The UK Plant Health Risk Register (PHRR) provides semiquantitative estimates of invasion probability and impact on host plants for PPDs thought to pose a risk to the United Kingdom to help prioritize biosecurity activities. The PHRR currently contains 636 PPDs potentially affecting 74 tree species found in the United Kingdom. …”
Get full text

Advancing Alzheimer’s disease detection: a novel convolutional neural network based framework leveraging EEG data and segment length analysis by Md Nurul Ahad Tawhid, Siuly Siuly, Enamul Kabir, Yan Li

“…Abstract Alzheimer’s disease (AD) is a progressive neurodegenerative disorder that primarily affects memory, thinking, and behavior, leading to dementia, a severe cognitive decline. While no cure currently exists, recent advancements in preventive drug trials and therapeutic management have increased interest in developing clinical algorithms for early detection and biomarker identification. …”
Get full text

Constitution of police sciences in the Slovak Republic by M. Lisoň, A. Vaško

“…Therefore, the authors of this paper accept that the theoretical and methodological development of police sciences requires them to be confronted and independently dealt with the current state in the theory and methodology of science in the early 21st century, to be sensitive to the current development of the overall scientific atmosphere and independently and critically. …”
Get full text

PROSPECTS FOR THE DEVELOPMENT OF BRAIN CYTOLOGICAL EXAMINATION IN PNEUMOCONIOSIS IN MINERS by Олег Иванович Бондарев, Сергей Николаевич Филимонов

“…Coal industry workers are characterized by a high level of occupational diseases, including pneumoconiosis. The current level of diagnosis is based on clinical research methods, which often do not determine early changes in the lungs. …”
Get full text

Impact of a Saline Soil Improvement Project on the Spatiotemporal Evolution of Groundwater Dynamic Field and Hydrodynamic Process Simulation in the Hetao Irrigation District by Yule Sun, Liping Wang, Zuting Liu, Yonglin Jia, Zhongyi Qu

“…Reducing irrigation to 80% of the current water supply of the Yellow River enables groundwater level stabilization (2.05 ± 0.12 m burial depth) within 5–7 years. …”
Get full text

Performance assessment of a novel design of double slope solar: Energy and water quality analysis by Sabir Widatalla, Hassan Mohammed, I.B. Sapaev, Ramachandran T, John William Grimaldo Guerrero, Aman Shankhyan, P Vijaya Kumar, Vikasdeep Singh Mann, Hossein Sharif

“…A further increase in temperature from 80°C to 90°C leads to a 141% increase in water production under the same wind conditions.…”
Get full text