Sialylation of prion protein controls the rate of prion amplification, the cross-species barrier, the ratio of PrPSc glycoform and prion infectivity. by Elizaveta Katorcha, Natallia Makarava, Regina Savtchenko, Alessandra D'Azzo, Ilia V Baskakov

“…The current study demonstrates that undersialylated PrP(C) is selected during prion amplification in Protein Misfolding Cyclic Amplification (PMCAb) at the expense of oversialylated PrP(C). …”
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Impact of Photovoltaic Penetration on the Distribution System Operation. Case Study Albania by Andi Hida, Olsi Karapici, Rajmonda Buhaljoti, Diamant Gashi

“…The increase in photovoltaic penetration, especially in the low voltage distribution system, requires the necessity to identify the problems it causes, as well as the benefits it provides. …”
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I tweet, therefore I am: a systematic review on social media use and disorders of the social brain by Nancy Yang, Bernard Crespi

“…In each case, the virtual nature of social media facilitates the delusionality because the self is defined and bolstered in this highly mentalistic environment, where real-life exposure of the delusion can be largely avoided. Current evidence also suggests that increased social media usage, via its disembodied and isolative nature, may be associated with psychotic spectrum phenotypes, especially delusionality, by the decoupling of inter and intra-corporeal cues integral to shared reality testing, leading to the blurring of self-other boundaries.…”
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METABOLIC REPROGRAMMING OF MICROGLIA AND ASTROCYTES AS A FACTOR IN THE REGULATION OF NEUROINFLAMMATION IN ISCHEMIC STROKE by Mikhail Bobrov, Vadim Nikitin, Marina Burak

“…This review presents current ideas about metabolic reprogramming in astrocytes and microglial cells in the context of pathophysiological processes in cerebral ischemia.…”
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Pre-industrial and future shifts in seasonal precipitation climatology for large river basins across the continental U.S.A by Kyungmin Sung, James H Stagge

“…These trends are projected to continue on their current trajectory through the end of the century. …”
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The Impact of Deforestation and Restoration Trends on Land Use and Land Cover Changes in Eastern Mau Forest Reserve, Kenya by Mike Passiany, Kyalo Kiema John Bosco

“… Context and Background This study aims to assess the environmental impact of Land Use and Land Cover (LULC) changes in the Eastern Mau Forest Reserve, Kenya, using remote sensing and GIS techniques. …”
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Quality improvement project to improve cardiovascular risk screening in patients with rheumatoid arthritis by Mireille Edens, Monique Hoekstra, Harriet de Vries, Clarinda van den Bosch-Schreuder

“…The CV risk screening in the Netherlands is performed by the general practitioner (GP).Purpose The aim of our project was to increase the CV risk screening of patients with RA, performed by the GP, from 46% to 65% of the selected patients of 40 years and older, within the time frame of our project (18 months).Context The project was carried out at the outpatient rheumatology clinic at Isala Zwolle, a large teaching hospital, in an area with 106 GP practices. …”
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Data-Driven Proactive Early Warning of Grid Congestion Probability Based on Multiple Time Scales by Haobo Fu, Ruizhuo Wang, Bingxu Zhai, Yuanzhuo Li, Pengyuan Li, Rui Zhang, Haoyuan He, Siyang Liao

“…With the development of new power systems, the increased interactive demand on the load side, and the high proportion of renewable energy sources on the power side, grid congestion problems due to increased system uncertainty are becoming more frequent. …”
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Impact of Sustainable Environmental Expenditures Policy on Air Pollution Reduction, During European Integration Framework by Ionel Bostan, Mihaela Onofrei, Elena-Doina Dascălu, Bogdan Fîrtescu, Carmen Toderascu

“…Pursuant to the growth of society, against the boosting of scientific and technological progress, also arises the negative effect of pollution acceleration. In this context, we relate to risks that imply the growth of pollution, especially against nuisance air pollution increase (CO, SO2, NO etc.) with major implications on the growth of greenhouse effect, the melting of the ice fields, respectively the pollution of the soil with nitrates from fertilizers intensively used in agriculture. …”
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Phenotypic and functional changes of NK cells in patients with myelodysplastic syndrome and acute myeloid leukemia treated with hypomethylating drugs by D. I. Zhigarev, M. V. Khoreva, L. V. Gankovskaya

“…Meanwhile, the origin of this change and its role are important in the context of the disease pathogenesis. Ultimately, a simple description of an increase or decrease in a single receptor expression is not illustrative, since it can lead to uncertain consequences. …”
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Renegotiating Social Citizenship - Democracy in Welfare Service States by Arne Wohlfarth

“…This article illustrates the importance of social services in the context of current social investment strategies. It outlines a program of new challenges, pitfalls and opportunities for the effective realization of welfare citizenship in a service-based welfare architecture by contextualizing sui-generis characteristics of social services in the area of tension between democratic demands and current forms of welfare architecture and provision. …”
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Association of plasma levels of Sestrin2 with adiposity and metabolic function indices in healthy and diabetic subjects from Qatar Biobank by Muhammad Ammar Zahid, Shahenda Salah Abdelsalam, Hicham Raïq, Hanan H. Abunada, Aijaz Parray, Abdelali Agouni

“…Conversely, in the diabetic cohort, higher Sestrin2 levels were paradoxically linked to increased triglycerides (OR: 1.57), the product of triglyceride glucose and waist circumference (OR: 1.8), body fat (OR: 1.72), waist circumference (OR: 1.82), waist-to-hip ratio (OR: 1.96) and metabolic syndrome (OR: 1.48).ConclusionsThese findings suggest that Sestrin2 may play a complex and context-dependent role in metabolic regulation, potentially serving as a protective factor in healthy individuals but contributing to metabolic dysfunction in the context of established diabetes. …”
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Enhancing malaria elimination in high-transmission settings: the synergy of concurrent vector control and chemotherapy by Ronald Mulebeke, Adoke Yeka, Jean-Pierre van Geertruyden

“…Thus, tailoring strategies to the specific local context and transmission dynamics is essential for maximizing impact. …”
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Public-private partnership in the field of cybersecurity by S.V. Sieriebriak

“…Thus, the article not only summarizes the current state of development of public-private partnerships in Ukraine, but also identifies priorities for its improvement, especially in the field of cybersecurity, which is a key component of national security in the face of current challenges. …”
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Voice quality types and uses in North American English by Richard Wright, Courtney Mansfield, Laura Panfili

“…While not contrastive, it plays an important role in phonology and a wide variety of other discourse, pragmatic, and social functions. In this context we present some of our current research into segmental and social factors relating to creaky voicing. …”
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Spiritual space: Hearing and experiencing the voice of God by Walter Firth

“…As scrutiny increases of what and how, such material is shared, used and taught, creating a space where the voice of God can speak into our current settings becomes increasingly vital. …”
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Monitoring ground temperature and deformation of the cast-in-place footings in permafrost regions on the Qinghai‒Tibet Plateau by Chao-Wei Wang, Yan-Hui You, Bin Yao, Bin Liu, Pei-Heng Guo, Lei Guo, Xin-Bin Wang, Qi-Hao Yu

“…The long-term stability of the cast-in-place footings in permafrost regions has received much attention due to its climate sensitivity. The current research lacks long-term data validation, especially in the context of climate change. …”
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Enhancing research on academic research capacity in Cambodian higher education institutions by Sarith Chiv, Kimcheang Hong, Chanthang Meak, Rany Sam, Morin Tieng, Hak Yoeng, Mardy Serey

“…This comprehensive approach provides a thorough understanding of Cambodia’s current academic research landscape, highlighting areas that require policy-driven solutions. …”
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Canine organoids: state-of-the-art, translation potential for human medicine and plea for standardization by Kim Verduijn, Kim Verduijn, Hilde de Rooster, Hilde de Rooster, Evelyne Meyer, Evelyne Meyer, Jonas Steenbrugge, Jonas Steenbrugge

“…However, in veterinary medicine, such applications are limited and largely confined to canine organoids. In the Cross Health context, the potential of canine organoids lies in the translation to human diseases, such as cancer. …”
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Industry 4.0 in Agriculture: Smart Agricultural Applications and Drone Use in Agriculture by Fatih Çağatay Baz

“…The agricultural sector has had to use new technologies in food production in recent years. The increase in the world population has necessitated the agricultural sector to produce more. …”
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