The impact of dropouts in scRNAseq dense neighborhood analysis by Alisa Pavel, Manja Gersholm Grønberg, Line H. Clemmensen

“…., cell pairs consistently being in the same cluster) decreases. This implies that sub-populations within cell types are increasingly difficult to identify under increasing dropout rates because observations are not consistently close.Our results challenge the current practice of using default clustering pipelines and the general assumption of identifiable local neighborhoods on high dropout data. …”
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Interleukin-35 impairs human NK cell effector functions and induces their ILC1-like conversion with tissue residency features by Valentin Picant, Lara Revol-Bauz, Laurie Tonon, Timothée Casini, Aurélien Voissière, Dominique Poujol, Emilie Picard, Céline Rodriguez, Cyril Degletagne, Emily Sible, Uzma Hasan, Anthony Ferrari, Christophe Caux, Nathalie Bendriss-Vermare

“…Abstract Natural Killer (NK) cells play pivotal immunological roles including direct cytotoxic effector function and secretion of inflammatory and immunomodulating cytokines. In the context of chronic inflammation, NK cell fitness decreases during disease progression through currently unknown mechanisms. …”
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Challenges to generating political prioritization for adolescent sexual and reproductive health in Kenya: A qualitative study. by Maricianah Atieno Onono, Claire D Brindis, Justin S White, Eric Goosby, Dan Odhiambo Okoro, Elizabeth Anne Bukusi, George W Rutherford

“…We examined factors that have shaped the lack of current political prioritization of adolescent SRH service provision.…”
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NEW APPROACHES TO THERAPY OF CLASSICAL PH-NEGATIVE MYELOPROLIFERATIVE DISEASES: THE EXPERIENCE OF EARLY THERAPY WITH CEPEGINTERFERON ALPHA-2B by A. S. Polyakov, Y. A. Noskov, V. V. Tyrenko, A. S. Lapshova, A. V. Kovalev

“…The limitations of classical cytoreduction and current targeted therapy, as well as the conviction of most specialists in the impossibility of adequately containment of disease progression, continue to be the main factors that keep physicians from the early start of pathogenetic therapy.Objective: to study the efficacy and safety of cepeginterferon alpha-2b (cePEG-IFN alpha-2b) in early (non-risk-adjusted) therapy of classical Ph-negative myeloproliferative neoplasms in initial use and after therapy with other pegylated interferons (PEG-IFN).Materials and methods. …”
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Self-other distinction modulates the sense of self-agency during joint actions by Laura Zapparoli, Marika Mariano, Lucia Maria Sacheli, Tommaso Berni, Caterina Negrone, Carlo Toneatto, Eraldo Paulesu

“…We discuss these results considering current cognitive theories on motor awareness and interactions.…”
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Flourishing as a highly sensitive person: a mixed method study on the role of nature connectedness and chaotic home environment by Susan Carroll, Anna O’Brien, Francesca Lionetti, Anna O’Reilly, Annalisa Setti, Annalisa Setti

“…IntroductionTheories of Environmental Sensitivity postulate that those who are highly sensitive thrive in favourable contexts and are more disadvantaged by unfavourable ones; however, negative outcomes, instead of positive, are more often investigated. …”
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Vertical distribution of ¹³⁷Cs in soddy-podzolic sandy soil in grasslands and forests of the Bryansk region in 2015–2016 by V. P. Ramzaev, A. N. Barkovsky, K V. Varfolomeeva

“…With increasing depth, the activity concentration decreased and reached a minimum in the deepest layers. …”
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Amyloidogenic immunoglobulin light chains disturb contractile function and calcium transients in a human cardiac spheroid model of light chain (AL) amyloidosis by Mélanie Bézard, Jean-Sébastien Vartanian-Grimaldi, Julien Henri, Denisa Calin, Amira Zaroui, Mounira Kharoubi, Thibaud Damy, Onnik Agbulut, Ekaterini Kordeli

“…LC-treated hiPSC-CM cultures and LC-containing spheroids presented structural and functional defects including: (1) decreased levels and subcellular disorganization of sarcomeric protein alpha-actinin; (2) abnormal accumulation of calcium handling SERCA2a protein; (3) impaired contractility of spheroids and altered calcium transients. …”
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Real time intelligent garbage monitoring and efficient collection using Yolov8 and Yolov5 deep learning models for environmental sustainability by Mohammed M. Abo-Zahhad, Mohammed Abo-Zahhad

“…Nationally, governments have initiated several programs to improve cleanliness by developing systems that alert businesses when it’s time to empty the bins. Current research proposes an enhanced, accurate, real-time object detection system to address the problem of trash accumulating around containers. …”
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The role of judicial authorities in criminal proceedings for political crimes in the Stalinist period: modern historiography by Alexander Ya. Kodintsev

“…A number of works on the history of the judicial authorities contain sections on the application of the rules of judicial procedure to political crimes. Currently, PhD theses, covering an increasing number of regions of Russia, are being defended actively. …”
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Invasive alien plant species, riverbank instability and hydraulic risk: what do we know about <i>Amorpha fruticosa</i>, <i>Arundo donax</i> and <i>Reynoutria japonica</i>? by Fabrizio Buldrini, Sara Landi, Giacomo Titti, Stefano Parodi, Massimo Valente, Lisa Borgatti, Rossano Bolpagni

“…Nevertheless, the reasons for the implications of increasing presence of IAPs on the stability and effectiveness of flood defences are still unclear. …”
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Research progress in intracranial artery dissections over past 25 years: a review and bibliometric analysis by Zixuan Zhou, Zixuan Zhou, Zixuan Zhou, Bingyang Qin, Yang Chen, Yang Chen, Yang Chen, Ren Li, Ren Li, Ren Li, Biao Yang, Biao Yang, Biao Yang, Ziao Li, Ziao Li, Ziao Li, Yongqiang Wu, Yongqiang Wu, Yongqiang Wu, Xiaogang Wang, Xiaogang Wang, Xiaogang Wang, Xiaolong Guo, Xiaolong Guo, Xiaolong Guo, Wenju Zhang, Wenju Zhang, Wenju Zhang, Yuanli Zhao, Geng Guo, Geng Guo, Geng Guo, Geng Guo, Geng Guo

“…Keyword analysis of the literature showed that “recanalization “reached the highest intensity of outbreaks, while “thrombectomy “,” outcome “, “risk “, and “diagnosis “showed an increase in citations in 2025, indicating that these subjects continue to be of significant interest.ConclusionThis study explores the evolving research trends and challenges in the area of IAD, presenting a thorough examination of both its historical and current research contexts. …”
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The role of Pakistan Medical & Dental Council in steering undergraduate medical curriculum reforms in Pakistan by Gohar Wajid, Lubna Baig, Syeda Kauser Ali, Usman Mahboob, Ahsan Sethi, Rehan Ahmed Khan

“…There has been an exponential increase in the number of medical colleges in Pakistan over the past few decades, especially in the private sector. …”
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The Chem-Sex Inventory Scale (CSI): A Tool to Assess the Mental Health Risk of Chemsex Behaviors in Men Who Have Sex with Men by Pablo Del Pozo-Herce, Enrique Baca-García, Antonio Martínez-Sabater, Rubén Pérez-Elvira, Vicente Gea-Caballero, Elena Chover-Sierra, Pedro José Satústegui-Dordá, Alberto Tovar-Reinoso, Francisco José Rodríguez-Velasco, Mercedes Sánchez-Barba, Jesús Pérez, Raúl Juárez-Vela

“…Drugs associated with chemsex can trigger mental health problems such as anxiety, depression, risk of psychosis and suicidal ideation, social isolation, stigmatization, and even loss of impulse control and lack of coping strategies. Currently, the increase in illicit drugs in a sexual context is considered an outbreak of a public health emergency. …”
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Early evaluation of salt-stress tolerance of new released olive cultivars based on physiological and biomass allocation indicators by Olfa Elloumi, Fathi Ben Amar, Ahmed Trigui, Kamel Gargouri, Mohamed Ghrab

“…‘Chemlali Sfax’ displayed a gradual significant decrease of vegetative growth with increasing salinity. …”
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Understanding How, Why and for Whom Link Work Interventions Promote Access in Community Healthcare Settings in the United Kingdom: A Realist Review by Rebecca Golby, Fiona Lobban, Louise Laverty, Kyriakos Velemis, Vishal R. Aggarwal, Katherine Berry, Abby Morris, Emma Elliott, Rebecca Harris, Al Ross, Carolyn A. Chew‐Graham, Miranda Budd, Linda McGowan, David Shiers, Neil Caton, Chris Lodge, Paul French, Robert Griffiths, Jasper Palmier‐Claus

“…Conclusion Although link work interventions are increasingly utilised across community healthcare settings, the contexts in which they operate vary considerably, triggering a range of mechanisms. …”
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Comprehensive Review of Intrusion Detection Techniques: ML and DL in Different Networks by Imane Rakine, Aziz Oukaira, Kamal El Guemmat, Issam Atouf, Sara Ouahabi, Mohamed Talea, Tarik Bouragba

“…With the increasing number of new attacks, virtualized and distributed networks require greater attention and investment in cybersecurity. …”
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Justificación del valor educativo de la Educación Física y el docente. ¿Qué profesional del deporte debe impartir la materia de Educación Física? ¿El Maestro/a y Profesor/a de Educ... by Vicente Miñana-Signes, Manuel Monfort-Pañego

“…This theoretical review aims at explaining and reflecting on what quality Physical Education and teachers’ professional competencies are, so as not to confuse it with school sports. Currently, there are several institutions that recommend a Quality Physical Education, and among other aspects they emphasize that this should increase up to 3 hours per week both in the stage of compulsory primary and secondary education. …”
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A collaborative approach to advancing research and training in Public Health Data Science—challenges, opportunities, and lessons learnt by Elisha Abade, Wondwossen Mulugeta, Idah Orowe, Getachew Hailemariam, Patrick Weke, Rahel Bekele, Isabelle Zaugg, Jeff Goldsmith, Tiffany Sanchez, Kiros Berhane

“…However, there is a severe lack of well-trained data scientists and home-grown educational programs to enable context-specific training. The lack of human capacity and resources for public health data analysis as well as the dire need to use modern technology for better understanding and possible intervention cannot be dealt with currently available educational programs and computing infrastructure, demanding a great deal of collaboration and investments within Africa and with the Global North This paper describes processes undertaken to establish sustainable research training programs and to train a new generation of data scientists with knowledge, mentoring, professional skills, and research immersion. …”
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Effects of intercropping with legume forage on the rhizosphere microbial community structure of tea plants by Yuhang Jiang, Yuhang Jiang, Yuhang Jiang, Xiaoqin Lin, Wenxiong Lin, Wenxiong Lin

“…ContextIntercropping in agriculture is crucial for addressing challenges in intensive tea farming. …”
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