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    Increasing day three parasitaemia is observed after treatment of patients with artemether-lumefantrine and single dose of primaquine for uncomplicated Plasmodium falciparum malaria... by Bontu Abate, Bokretsion Gidey Brhane, Tsegahun Manyazewal, Hussien Mohammed, Yonas Wuletaw, Moges Kassa, Mesay Hailu, Getachew Tollera, Geremew Tasew, Ashenafi Assefa, Eyasu Makonnen

    Published 2025-03-01
    “…These findings support the ongoing use of AL with a single dose of PQ as the primary treatment option for uncomplicated P. falciparum infections in the study area. In the context of the emergence and spread of partial artemisinin-based combination therapy(ACT) resistance in Africa, regular monitoring of the efficacy of current artemisinin-based combinations is recommended for the early detection of emerging drug resistance in the study setting and beyond.…”
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  3. 523

    The Functional Impact of VX-770 on the Cystic Fibrosis Transmembrane Conductance Regulator Is Enduring and Increases the Constitutive Activity of This Channel in Primary Airway Epi... by Heidi J. Nick, Sarah E. Christeson, Preston E. Bratcher

    Published 2024-10-01
    “…Acute VX-770 exposure resulted in an increase in CFTR-mediated currents in the absence of exogenous compounds that induce the phosphorylation/activation of CFTR, with acute exposure having the same effect as chronic exposure. …”
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    A multi-level implementation strategy to increase adoption of chiropractic care for low back pain in primary care clinics: a randomized stepped-wedge pilot study protocol by Eric J. Roseen, André Bussières, Rocky Reichman, Celia Bora, Jennifer Trieu, Kirsten Austad, Charles Williams, Ryan A. Fischer, Danielle Parrilla, Lance D. Laird, Michael LaValley, Roni L. Evans, Robert B. Saper, Natalia E. Morone

    Published 2025-02-01
    “…., manual therapy, exercise instruction, advice on self-care), implementation strategies to increase adoption of chiropractic care for LBP in primary care clinics are understudied, particularly in underserved communities. …”
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    Realist evaluation of Autism ServiCe Delivery (RE-ASCeD): which diagnostic pathways work best, for whom and in what context? Findings from a rapid realist review by Patricia M Wilson, Venkat Reddy, Ian Male, William Farr, Jeremy Parr, Vanessa Abrahamson, Wenjing Zhang, Anna Peckham

    Published 2021-12-01
    “…Objectives Waiting times in the UK for an autism diagnostic assessment have increased rapidly in the last 5 years. This review explored research (including ‘grey’ literature) to uncover the current evidence base about autism diagnostic pathways and what works best, for whom and in what circumstances, to deliver high quality and timely diagnosis.Design We performed a Rapid Realist Review consistent with recognised standards for realist syntheses. …”
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