High prevalence of the hotspot complement factor I p.Ile357Met pathogenic variant in Tunisian atypical hemolytic uremic syndrome patients: report of three new cases and review of t... by Asma Tajouri, Asma Tajouri, Asma Tajouri, Imen Ayadi, Imen Ayadi, Rimeh BenBrahim, Rimeh BenBrahim, Ikram Mami, Abir Boussetta, Hend Jlajla, Hend Jlajla, Yousr Zerzeri, Haifa Arbi Sassi, Jamila Ben Sassi, Hela Sahli, Lilia Laadhar, Lilia Laadhar, Tahar Gargah, Mohamed Karim Zouaghi, Maryam Kallel Sellami, Maryam Kallel Sellami

“…The recurrence of this variant in the Tunisian cohort led us to suggest that it could be characteristic of the Tunisian population.MethodsIn this context, we conducted the current study which included 8 adults and three children with suspected aHUS and decreased factor I levels, as well as one relative. …”
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Everyday living with osteoarthritis in the global South: A qualitative focus group inquiry in Nigeria by Tolulope Owoyemi, Ibidunni Alonge, Oladapo Adetunji, Emmanuel Ogbu, Adebimpe Ogunbanjo, Simon White, Adewale Adebajo, Christian Mallen, Opeyemi O. Babatunde, Krysia Dziedzic

“…This study aimed to explore lived experiences, expressed needs and current care gaps for people living with osteoarthritis in low-health resource contexts using Nigeria as a case study. …”
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Comparison of the indirect immunofluorescence assay and a commercial ELISA to detect KSHV antibodies by Valentin Leducq, Léa Ben Said, Sophie Sayon, Vincent Calvez, Anne-Geneviève Marcelin, Aude Jary

“…The current gold-standard method, the indirect immunofluorescence assay (IFA), has a very good specificity of close to 100%, but a lower sensitivity of around 80–85%, which decreases to 64–67% in immunocompromised patients. …”
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Developing and presenting a mathematical model for the purpose of organizational culture architecture based on creating alignment between the strategic reference points of organiza... by Elyas hasanzadeh Shweili, Mir Mehrdad peidaie, Ali reza Rezghi Rostami

“…These values ​​are the focus of many organizational phenomena, such as organizational culture; which provides the context of self-control and counter-control and gives it direction (Abedelrahim, 2018). …”
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Repetitive transcranial magnetic stimulation for the treatment of suicidality in opioid use disorder: a pilot feasibility randomized controlled trial by Victor M. Tang, Bernard Le Foll, Zafiris J. Daskalakis, An-Li Wang, Leslie Buckley, Daniel M. Blumberger, Daphne Voineskos

“…Conclusion We present the first data piloting a structural neuroimaging-guided, multi-session rTMS treatment course in outpatients with suicidality and OUD in the current North American context. Recruitment and retention were the main challenges given the highly unstable medical and psychosocial context of this patient population. …”
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A comprehensive review of methodologies and application to use the real-world data and analytics platform TriNetX by Ralf J. Ludwig, Ralf J. Ludwig, Ralf J. Ludwig, Matthew Anson, Matthew Anson, Henner Zirpel, Diamant Thaci, Henning Olbrich, Katja Bieber, Khalaf Kridin, Khalaf Kridin, Khalaf Kridin, Astrid Dempfle, Philip Curman, Philip Curman, Philip Curman, Philip Curman, Sizheng S. Zhao, Uazman Alam, Uazman Alam, Uazman Alam

“…TriNetX’s federated network architecture allows real-time, privacy-compliant data access, significantly enhancing the ability to conduct retrospective studies and refine clinical trial designs. With access to currently over 150 million EHRs, TriNetX has proven particularly effective in filling gaps left by RCTs, especially in the context of rare diseases, rare endpoints, and diverse patient populations. …”
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Valorising mango, cashew apple, and papaya by-products for sustainable small ruminant production in low-income food deficit countries—a review by Antoinette Simpah Anim-Jnr, Salma Binta Yusif Ishaq, Prince Sasu, Sadat Gyimah, Henry Michael Rivers Greathead, Christine Boesch, Faith Philemon Mabiki, Mohammad Naushad Emmambux

“…It emphasizes the need for further research to determine their nutritional value in local contexts, establish optimal inclusion levels, and devise strategies for prolonging shelf life. …”
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Development of a Correlation Model of Adherence to Sports With the Mental Health of Students Participating in Sports Leisure Time by Ahmad Mahmoudi, Mohammad Ghasemi, Reza Amin Zadeh, Danesh Zamani Rad

“…Informing people about the positive effects of physical activities on different body systems increased the tendency towards sports activities (Mostafavirad & Dehghan, 1397). …”
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Interior Point Algorithm in Multi-objective Portfolio Optimization: GlueVaR Approach by Elaheh Gohania, Gholamreza Mansourfar, Fahimeh Biglari

“…Conclusion Based on the current findings, it is evident that the internal point algorithm is effective in resolving stock portfolio optimization issues. …”
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Manganese for Whom? A Review on Manganese Mining Permits towards the Existence of Springs’ Sacred Forest in Manggarai Flores by Bernadinus Steni, Hariadi Kartodihardjo, Soeryo Adiwibowo, Ruchyat Deni Djakapermana

“…Both the spatial analysis and qualitative data are then analyzed alongside the legal framework of land use and spring used to distill the institutional barriers leading to the issuance of permits in such contexts. The analysis then briefly traces the current political economy of mining’s permits underlying the institutional interactions to better understand why the institutions behave as they do. …”
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Genomic Insights into and Lytic Potential of Native Bacteriophages M8-2 and M8-3 Against Clinically Relevant Multidrug-Resistant <i>Pseudomonas aeruginosa</i> by Francisco Ricardo Rodríguez-Recio, Javier Alberto Garza-Cervantes, Francisco de Jesús Balderas-Cisneros, José Rubén Morones-Ramírez

“…Their safety profile, high target specificity, and robust lytic activity underscore the feasibility of incorporating phage-based strategies into current antimicrobial protocols. This study contributes to the broader goal of developing sustainable and effective phage therapies for diverse clinical and environmental contexts.…”
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Medical embryology and regenerative medicine: research and applications in clinical practice by Julia Soczyńska, Julia Soczyńska, Wiktor Gawełczyk, Wiktor Gawełczyk, Patrycja Obrycka, Patrycja Obrycka, Mateusz Żołyniak, Mateusz Żołyniak, Adrian Muzyka, Adrian Muzyka, Krzysztof Majcherczyk, Krzysztof Majcherczyk, Julia Papierkowska, Julia Papierkowska, Sławomir Woźniak

“…Taking this progress a step further, the ability to introduce stem cells into damaged tissues, thereby facilitating the formation of functional structures, has led to the growing interest in organoids -three-dimensional models that replicate key functions of real organs. Organoids are currently applied not only in drug screening but are also gaining increasing attention for their role in cancer therapy research. …”
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Advancing life cycle assessment of bioenergy crops with global land use models by Anders Arvesen, Florian Humpenöder, Tomás Navarrete Gutierrez, Thomas Gibon, Paul Baustert, Jan Philipp Dietrich, Konstantin Stadler, Cristina-Maria Iordan, Gunnar Luderer, Alexander Popp, Francesco Cherubini

“…We find that land use-related CO _2 emission for bioenergy range from 2 to 35 tonne TJ ^−1 , depending on bioenergy demand, policy context, year and accounting method. GHG emissions per unit of bioenergy do not increase with bioenergy demand in presence of an emission tax. …”
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The Symbiotic Bacterial Profile of Laboratory-Reared and Field-Caught <i>Aedes albopictus</i> Mosquitoes from Greece by Elias Asimakis, Ioannis Galiatsatos, Georgia Apostolopoulou, Eleni C. Savvidou, Georgios Balatsos, Vasileios Karras, Vasiliki Evangelou, Eva Dionyssopoulou, Antonios Augustinos, Nikos T. Papadopoulos, Antonios Michaelakis, Panagiota Stathopoulou, George Tsiamis

“…The use of symbiotic bacteria to improve the application of SIT or design combined SIT/incompatible insect technique (IIT) approaches is currently considered. In this context, exploring the microbiota of local mosquito populations is crucial for identifying interesting components. …”
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Prevalence and associated factors of tuberculosis among diabetic patients attending public health facilities in Ethiopia: a multicenter study by Ayinalem Alemu, Getachew Seid, Getu Diriba, Michael Hailu, Biniyam Dange, Shewki Moga, Daniel Melese, Gemechu Tadesse, Solomon H Mariam, Nega Berhe, Balako Gumi

“…Abstract Background Individuals with diabetes mellitus (DM) have high tuberculosis (TB) prevalence. Currently, the incidence of DM is increasing in low and middle-income countries including Ethiopia where TB is also endemic, which may complicate TB prevention and control efforts. …”
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Evaluation of urban energy transition and identification of barrier factors under the “dual carbon” goals: an empirical study of the Yangtze River economic belt by Haoran Yan, Jingke Gao, Shixiang Li, Jun Bai, Ziyuan Liu, Chen Mai

“…The results show: (1) The overall level of urban energy transition increased by 35.86%, with persistent inter-city disparities, though their intensity has been alleviated. …”
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How do grit and academic stress influence academic performance? The role of academic self-efficacy as a mediator and moderator variable by Muh Daud, Dian Novita Siswanti, Dwi Yan Nugraha, Edwin Adrianta Surijah

“…Online learning systems are currently the primary approach to delivering information and facilitating learning for postgraduate students, replacing traditional in-person methods in many contexts. …”
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A group psychological intervention for postnatal depression in British mothers of South Asian origin – the ROSHNI-2 RCT by Nusrat Husain, Karina Lovell, Carolyn A Chew-Graham, Farah Lunat, Penny Bee, Matthias Pierce, Najia Atif, Saadia Aseem, Kamaldeep Bhui, Peter Bower, Traolach Brugha, Nasim Chaudhry, Akbar Ullah, Linda Davies, Nadeem Gire, Deepali Sharma, Jahanara Miah, Waqas Ahmed, Joe Kai, Ilyas Mirza, Jillian Morrison, Naeem Mohmed, Atif Rahman, Shanaya Rathod, Najma Siddiqi, Waquas Waheed, Christopher Williams, Nosheen Zaidi, Richard Emsley, Richard Morriss

“…An additional substudy was incorporated following the pandemic to explore the impact of other associated risk factors related to maternal mental health and specifically in the pandemic’s context. We aimed to increase the understanding of the pandemic-related impact on BSA women, including interpersonal violence (IPV) in their communities. …”
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Protecting the Autonomy of Patients with Severe Mental Illness Through Psychiatric Advance Directive Peer-Facilitation by Nicholas Karasik

“…Guiding Distributive Justice: Capability Theory Capability theory is an account of justice opportunity that places a fundamental moral significance on individuals' ability to reach proper functioning and well-being.[52] Whether or not an individual can make use of a particular set of resources and convert them into a state of functioning depends on personal, sociopolitical, and environmental conditions ("conversion factors").[53] In this sense, liberty is not the absence of restraint from others or institutions but the freedom achieved through capability-enhancing relationships.[54] Within the context of bioethics, capability theory shifts focus toward creating circumstances by which individuals can direct their lives as they choose.[55] Acting in accordance with the principle of beneficence, peer-support specialists could enhance the capability of patients to be self-determined and autonomous, which would promote patient well-being and empowerment.[56] Those living with SMI, such as schizophrenia and bipolar disorder, are among the most disadvantaged in society, experiencing social and economic hardship related to their illness.[57] These individuals are often feared and rejected by others, which increases depression, lowers self-esteem, and engenders feelings of social isolation.[58] Compounding their challenges, especially for those facing structural inequalities, is insufficient access to appropriate mental health services supporting recovery.[59] Capability theory provides a sound justification for the resource distribution necessary to create and sustain a thriving network of peer-support specialists, to which those with SMI currently do not have access. …”
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Mapping the Dream: Designing Optimal E-Bike Routes in Valparaíso, Chile, Using a Multicriteria Analysis and an Experimental Study by Vicente Aprigliano, Catalina Toro, Gonzalo Rojas, Iván Bastías, Marcus Cardoso, Tálita Santos, Marcelino Aurélio Vieira da Silva, Emilio Bustos, Ualison Rébula de Oliveira, Sebastian Seriani

“…These findings challenge the current regulatory limit of 250 W for non-motorized vehicles in Chile, highlighting the potential benefits of increasing their power limits to enhance sustainable mobility in the hilly urban contexts of this country. …”
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