Examining the longitudinal associations between activity limitations, instrumental supports and social participation in osteoarthritis: A CLSA population-based study. by Anthony V Perruccio, Calvin Yip, J Denise Power, Mayilee Canizares, Elizabeth M Badley

“…<h4>Objective</h4>In osteoarthritis (OA) research, disability is largely studied within the context of activities of daily living. Broader consequences for social participation are often overlooked. …”
Get full text

Introducing the non-invasive prenatal test for trisomy 21 in Belgium: a cost-consequences analysis by Mattias Neyt, Frank Hulstaert, Wilfried Gyselaers

“…The objective is to estimate the consequences of introducing NIPT for the detection of T21.Methods A cost-consequences analysis was performed presenting the impact on benefits, harms and costs. Context-specific real-world information was available to set up a model reflecting the current screening situation in Belgium. …”
Get full text

Interleukin-35 impairs human NK cell effector functions and induces their ILC1-like conversion with tissue residency features by Valentin Picant, Lara Revol-Bauz, Laurie Tonon, Timothée Casini, Aurélien Voissière, Dominique Poujol, Emilie Picard, Céline Rodriguez, Cyril Degletagne, Emily Sible, Uzma Hasan, Anthony Ferrari, Christophe Caux, Nathalie Bendriss-Vermare

“…Abstract Natural Killer (NK) cells play pivotal immunological roles including direct cytotoxic effector function and secretion of inflammatory and immunomodulating cytokines. In the context of chronic inflammation, NK cell fitness decreases during disease progression through currently unknown mechanisms. …”
Get full text

Reducing mine water contamination at the local drainage facility of a kimberlite mine by N. P. Ovchinnikov

“…As Russian kimberlite mines reach their design capacity, the interval between cleaning cycles of the local drainage system’s water collectors has significantly decreased. Currently, at kimberlite mines, the cleaning of silted water collectors is routinely carried out using all available load–haul–dump (LHD) machines operated by the mine’s Mechanical and Power Service. …”
Get full text

Teaching English Oral Expressionand Listening Comprehension at the Department ofLetters and English Language, University of Constantine 1: Past and Present Ups and Downs by Youcef BEGHOUL

“…It also suggests some solutions for a more practical teaching of these two crucial skills in a pedagogical context characterized by ever decreasing linguistic and cultural levels and more and more overcrowded classes.…”
Get full text

‘Just because something works doesn’t mean it can’t be improved’: an ethnographic analysis of the health system in Black Panther’s Wakanda by Jennifer Jackson, Carla Ferreira, Samantha Perry, Carla Ginn, Melissa Scott, Elke Jaibeeh Barah, Zahra Upal, Krista Phelps, Carol Mei, Haneul Woo, Megan Tung, Farida Gadimova, Alexandra Ewanyshyn, Twyla Ens

“…The emergence of COVID-19 (SARS-CoV-2) has introduced significant global challenges for healthcare systems, healthcare professionals and patients. This current climate creates an opportunity to learn from equitable health systems and move toward making fundamental changes to healthcare systems. …”
Get full text

Beyond the brain: early autonomic dysfunction in Alzheimer’s disease by Carmen Nanclares, Inés Colmena, Alicia Muñoz-Montero, Andrés M. Baraibar, Ricardo de Pascual, Aneta Wojnicz, Ana Ruiz-Nuño, Antonio G. García, Adrián Gironda-Martínez, Luis Gandía

“…These changes were accompanied by diminished sodium (INa), calcium (ICa), and nicotinic (IACh) currents, compromising CC excitability. With age, a shift toward increased potassium (IK) currents and enhanced catecholamine secretion may reflect compensatory adaptations aimed at preserving output. …”
Get full text

What type of leadership is more effective for managing change during force majeure? Achieving organizational effectiveness during the pandemic by Nazia Habib, Shaheryar Naveed, Muhammad Mumtaz, Rabia Sultana, Shoaib Akhtar

“…Hence, it was important to identify effective leadership styles to successfully manage the transformational process during the period. Therefore, the current study aims to explore and compare the effectiveness of transformational and ethical leadership (EL) in terms of achieving organizational goals during COVID-19 in public and private sector organizations in Pakistan. …”
Get full text

THE IMPACT OF THE USE OF BIOFUELS ON CO2 EMISSIONS AT THE LEVEL OF EUROPEAN COUNTRIES FROM THE PERSPECTIVE OF ABSOLUTE DECOUPLING by Valentina SIMION, Liviu MARCUTA, Maricel CAZACU, Nicolae MINEA, Camelia HODOAȘAN

“…Decoupling economic growth from CO2 emissions completely is still a key goal of sustainability programs. According to the current research, nations with faster energy transitions and advanced technologies typically see a sharper decoupling, meaning that real GDP growth is attained without a rise in greenhouse gas emissions. …”
Get full text

Adverse birth outcome research case definitions associated with maternal HIV and antiretroviral drug use in pregnancy: a scoping review by Kopano R. Dube, Shani T. de Beer, Kathleen M. Powis, Michael McCaul, Amy L. Slogrove

“…Abstract Background Adverse birth outcomes (preterm birth, low birth weight, small for gestational age, and stillbirth) seem to persist in infants born to people with HIV, even in the context of maternal antiretroviral therapy. However, findings have been disparate, inconclusive, and difficult to compare directly across settings, partly owing to variable outcome definitions. …”
Get full text

Application of urinary peptide-biomarkers in trauma patients as a predictive tool for prognostic assessment, treatment and intervention timing by Gökmen Aktas, Felix Keller, Justyna Siwy, Agnieszka Latosinska, Harald Mischak, Jorge Mayor, Jan Clausen, Michaela Wilhelmi, Vesta Brauckmann, Stephan Sehmisch, Tarek Omar Pacha

“…Preemptive personalized treatment aimed at preventing these events is a crucial objective of patient management; however, the currently available scoring systems provide only moderate guidance. …”
Get full text

Financial security of Ukraine in debt burden: Assessment and forecasting by Fedir Zhuravka, Yuriy Petrushenko, Svitlana Chorna, Bohdana Huriy, Inessa Yarova, Olga Pankiv, Wojciech Duranowski

“…This study aims to comprehensively assess the state’s financial security of Ukraine in the context of mounting debt and economic instability. …”
Get full text

ISSUES AND TRENDS OF PROGRESS TOWARDS SUSTAINABLE DEVELOPMENT GOALS IN ROMANIA by Dumitru Florin FRONE, Simona FRONE

“…Monitoring SDG 12 in an EU context focuses on progress made in decoupling environmental impacts from economic growth, in decreasing energy consumption and in tackling waste generation and management. …”
Get full text

Ramadan fasting and exercise combination therapy: A novel approach for osteoporosis prevention in ovariectomized rats by Tarfa Albrahim, Raghad Alangry, Raghad Alotaibi, Leen Almandil, Sara Alburikan, Hisham S. Aloudah, Mohammed Alahmed, Mohammed Alahmed, Mona Alonazi

“…This could be recommended as a lifestyle modification that is protective against osteoporosis, especially in the context of depleted estrogen hormone after menopause.…”
Get full text

Monitoring of hepatitis E virus infection and replication by functional tagging of the ORF2 protein by Maliki Ankavay, Nathalie Da Silva, Angela Pollán, Noémie Oechslin, Katja Dinkelborg, Patrick Behrendt, Darius Moradpour, Jérôme Gouttenoire

“…Understanding of the mechanisms underlying productive HEV infection remains incomplete and would benefit from technological advances improving current model systems. Methods: We exploited transposon-mediated random insertion and selection of viable clones to identify sites in the HEV open reading frame 2 (ORF2) protein, corresponding to the viral capsid, allowing for the insertion of reporter sequences in a functional context. …”
Get full text

The impacts of climate variability on conflict risk in conflict-prone regions worldwide by Xiaolan Xie, Fangyu Ding, Mengmeng Hao, Jun Zhuo, Shuai Chen, Jiajie Wu, Jiping Dong, Kai Sun, Qian Wang, Dong Jiang

“…The climate-conflict linkage is a topic of intense debate within the context of security implications. Previous quantitative studies exploring the causal link between climate variability and conflict risk present divergent findings due to the differences in modeling scale or strategies, such as the non-unified definition of conflict risk and the different settings of independent variables. …”
Get full text

Unlocking the potential of global greenhouse gas mitigation by reducing food loss and waste by Suraj Negi, Liang-Shih Fan, Hyunook Kim, Taira Hidaka, Aishwarya Rani, Shu-Yuan Pan

“…Food loss and waste (FLW) are significant yet under-addressed contributors to global greenhouse gas (GHG) emissions, and the effectiveness of current FLW mitigation policies and valorization technologies remains insufficiently explored. …”
Get full text

Temporal and Spatial Evolution and Driving Force Analysis of Water Conservation Function in Yunnan Province Based on Climate and Land Use Change by LIU Fengru, ZHAO Junsan, LIN Yilin, CHEN Guoping, ZHANG Longjiang, PENG Sufen

“…Existing research mainly focuses on the assessment of historical and current water-holding function, and lacks the understanding of the future water-holding function, which limits the value of guiding the sustainable development and dynamic management of the region. …”
Get full text

Insomnia, Cognitive Impairment, or a Combination of Both, Alter Lipid Metabolism Due to Changes in Acylcarnitine Concentration in Older Persons by Selma Karime Castillo-Vazquez, Berenice Palacios-González, Marcela Vela-Amieva, Isabel Ibarra-González, Ricardo Morales, Paola García-delaTorre, Sergio Sánchez-García, Carmen García-Peña, Ricardo Reyes-Chilpa, Raúl Hernán Medina-Campos, Jessica Hernández-Pineda, Juan Carlos Gomez-Verjan, Nadia Alejandra Rivero-Segura

“…Therefore, in the present study we aim to characterise metabolomic profiles of insomnia and CI alone in order to address a significant gap in current research regarding the pathways through which insomnia may lead to CI in older persons. …”
Get full text

Compost from the food waste for organic production of cabbage, cauliflower, and radish under sub-tropical conditions by Neha Kumari, Anit Sharma, Mamta Devi, Atif Zargar, Sunny Kumar, Umesh Thakur, Ajay Bhatia, Khushboo Badhan, Sunaina Chandel, Arpana Devi, Kriti Sharma, Shweta Kumari, Mussarat Choudhary, Arup Giri

“…Purpose In the current scenario, food wastage is a significant concern throughout the world. …”
Get full text