Stress and influencing factor among children diagnosed with cancer at hospitals in Nepal: a cross-sectional study by Surya Kamal Shahi, Panpan Wang, Jinjin Gu, Rajendra Man Shrestha, Peng Wang

“…The linear regression model showed that stress is associated with socio-demographic variables sex in which female children are more stressed (β = 1.750 (95% CI: 0.46, 3.03) P < 0.05) and clinical features duration of diagnosis as the time increase (12 < Month ≤ 24) level of stress decreased (β =-1.730 (95% CI: -3.20,-0.25) P < 0.05. …”
Get full text

Errors in the diagnosis of types of diabetes mellitus: causes and prevention strategies (literature review and own research results) by K.I. Gerush, N.V. Pashkovska, O.Z. Ukrainets

“…This is due to the increasing heterogeneity of DM, blurring of the boundaries between its types, atypical disease course, the decreased diagnostic value of the essential criteria for DM types (age, presence of metabolic syndrome signs, ketosis, dependency on insulin therapy), presence of comorbid conditions, and limited availability of diagnostic tests to specify the type of diabetes. …”
Get full text

Theoretical Research on the Shear Mechanical Properties and Size Effect of Recycled Concrete Beams Without Stirrups by Chunyang Liu, Guangkai Zhou, Hao Wang, Yilin Wang

“…As a new type of building material with great potential, recycled concrete is playing a vital role in the context of the current construction industry’s pursuit of sustainable development. …”
Get full text

Morphological features of the poultry thymus by S. V. Huralska, N. V. Dyshliuk, S. S. Zaika, H. P. Hryshchuk, L. H. Yevtukh

“…It was found that with the growth and development of chicks, the absolute and relative weight of the thymus increases. However, at the onset of reproductive maturity, these values decrease significantly. …”
Get full text

International Labor Migration and Its Transformative Effects on Political Landscapes Across Central Asian Nations by Egor V. Fomin, Albert A. Averyanov

“…This study concludes that any reduction in migratory activities, decreased inflows of remittance funds, or diminished organic inclination toward closer ties among migrants would result in both increased political volatility within Central Asia and weakened Russian leverage over the area.…”
Get full text

Molecular mechanisms underlying Tao-Hong-Si-Wu decoction treating hyperpigmentation based on network pharmacology, Mendelian randomization analysis, and experimental verification by Jun Chen, Wenyi Ye

“…Context Hyperpigmentation, a common skin condition marked by excessive melanin production, currently has limited effective treatment options.Objective This study explores the effects of Tao-Hong-Si-Wu decoction (THSWD) on hyperpigmentation and to elucidate the underlying mechanisms.Materials and methods We employed network pharmacology, Mendelian randomization, and molecular docking to identify THSWD’s hub targets and mechanisms against hyperpigmentation. …”
Get full text

Improving outcomes for people with autism spectrum disorders by reducing mental health problems: the IAMHealth research programme including one RCT by Emily Simonoff, Gillian Baird, Bryony Beresford, Tony Charman, Martin Knapp, Andrew Pickles, Carol Povey, Tom Purser, Paramala Santosh, Vicky Slonims, Stephen Scott

“…Factors contributing to this included beliefs about the causes of MHP and increased vulnerability with the context of a diagnosis of autism, knowledge of self-management and, based on prior experiences, a view that professional support or intervention was unavailable or inadequate. …”
Get full text

Micro nutrients as immunomodulators in the ageing population: a focus on inflammation and autoimmunity by Bhavani Sowndharya Balamurugan, Mathan Muthu Chinnakannu Marimuthu, Vickram Agaram Sundaram, Bharath Saravanan, Prasanth Chandrababu, Hitesh Chopra, Tabarak Malik

“…For example, it points out the modulatory effects of vitamin D on both innate and adaptive immunity, with a specific focus on its ability to suppress pro-inflammatory cytokines synthesis while enhancing regulatory T-cell function. In the same context, also zinc is described as important nutrient for thymic function and T-cell differentiation but exhibits immunomodulatory functions by decreasing inflammation. …”
Get full text

Comparison of Bone Mineral Density in Lumbar Spine and Fracture Rate among Eight Drugs in Treatments of Osteoporosis in Men: A Network Meta-Analysis. by Ling-Xiao Chen, Zhi-Rui Zhou, Yu-Lin Li, Guang-Zhi Ning, Tian-Song Zhang, Di Zhang, Shi-Qing Feng

“…Zoledronate ranked first for increasing the BMD in LS, and teriparatide (20mg) was ranked first for decreasing the fracture rate.…”
Get full text

Contrasting Effect of Curcumin on Hepatitis B Virus Replication According to the Hepatoma Cell Line by María Mercedes Elizalde, Pedro Fuentes, Diego Chiappetta, Diego Martín Flichman

“…In recent decades, considerable advances have been achieved in the treatment of chronic hepatitis B. However, the currently available drugs have shortcomings. In this context, several natural compounds have been proposed as potential agents to improve either the outcome of antiviral treatment or the progression of chronic infection, with curcumin being one of the most evaluated compounds due to its pleiotropic antiviral activity. …”
Get full text

Strategies for adaptation of Russian commercial banks to innovative technologies by O. S. Solenaya

“…All banking innovations have a significant impact on the current business models of commercial banks, increasing the efficiency of their activities and at the same time the level of competition both in the banking sector and in the financial markets as a whole…”
Get full text

Granulocyte-Macrophage Colony-Stimulating Factor Inhibition Ameliorates Innate Immune Cell Activation, Inflammation, and Salt-Sensitive Hypertension by Hannah L. Smith, Bethany L. Goodlett, Gabriella C. Peterson, Emily N. Zamora, Ava R. Gostomski, Brett M. Mitchell

“…Adoptive transfer of aGM-treated BMDMs into SSHTN mice resulted in decreased renal trafficking. Additionally, aGM treatment of BMD-Macs, CD38+ BMD-M1 Macs, BMD-DCs, and CD38+ BMD-cDC2s led to decreased pro-inflammatory gene expression. …”
Get full text

An Agent-Based Simulation and Optimization Approach for Sustainable Urban Logistics: A Case Study in Lisbon by Renan Paula Ramos Moreno, Rui Borges Lopes, Ana Luísa Ramos, José Vasconcelos Ferreira, Diogo Correia, Igor Eduardo Santos de Melo

“…The research focuses on a real-world case study, comparing the company’s current operational scenario with an optimized scenario generated through a PDP-TW model adapted from the literature. …”
Get full text

Mapping evidence of spinal manipulation therapy for headaches in South Africa: a scoping review of grey literature by Keseri Padayachy, Ismail Fatima, Morris Kahere, Alister du Rose, Katherine A. Pohlman

“…In terms of objective measures, there were both increases and decreases across the different interventions. …”
Get full text

Cost-utility of aripiprazole once-monthly versus paliperidone palmitate once-monthly injectable for schizophrenia in China. by Yiping An, Gang Fang, Zhipeng Pi, Yumeng Zhang, Wei Li, Jinxi Ding

“…A cost-effectiveness threshold (CET) of 0.51 times China's 2023 gross domestic product (GDP) (US$ 6,394.536) was used to judge the economics of intervention.<h4>Results</h4>The current price of AOM in China is relatively high (US$418.140). …”
Get full text

Banking Models Under the Impact of the Post-Crisis Organizational Changes Apt to Confer Sustainable Financial Stability - Romanian Experience by Claudia Gabriela Baicu, Olimpia State

“…The banking model practiced in Romania continues to be the traditional one. Currently, the most important challenges of the Romanian banking system are the growth of the non-performing loans, the loans in foreign currency to unhedged borrowers, the pressure to meet the Basel III requirements, as well as the possibility that the exposure of foreign banks towards Romania to decrease.…”
Get full text

Matrix Gla Protein – a new marker for colorectal cancer detection? A systematic review by Mirela-Georgiana Perné, Lorena Ciumărnean, Olga-Hilda Orășan, Vasile Negrean, Teodora-Gabriela Alexescu, Mircea Vasile Milaciu, Ioana Roșca, Răzvan Dan Togănel, Gabriel Emil Petre, Lucia Procopcoiuc, Cristina Drugan, Alexandra Crăciun

Get full text

Determining the Teachers' Attitude towards "Mistake" and "Making Mistakes" in the Learning Process and Improving the Culture facing it (case study: elementary school students) by Mazhar Babaee, Hedyeh Azagh

“…They showed that learning from mistakes increases the productivity of human resources in the organization.Also, in response to the second research question, findings were obtained in two themes and 22 concepts. …”
Get full text

miR-34a-5p modulation of polycystic ovary syndrome via targeting the NOTCH signaling pathway by Kexin Zhang, Xiaomeng Wang, Fang Liu, Hong Lin, Yan Wang, Min Zhao, Xiaofei Wang, Yijing Chu, Lin Xu

“…Conversely, inhibiting miR-34a-5p resulted in an increase in cell growth and a decrease in programmed cell death. …”
Get full text

Cost-effectiveness of atezolizumab plus bevacizumab versus sorafenib as first-line therapy in unresectable hepatocellular carcinoma in the US and Chinese setting: a modelling compa... by Lei Wang, Lulu Liu, Yiling Ding, Qilin Zhang, Yamin Shu

“…In scenario analyses, the atezolizumab plus bevacizumab treatment becomes favourable when the cost of atezolizumab decreases to 67.85% and 18.45% of its original price in the USA and China, respectively.Conclusions The atezolizumab plus bevacizumab is unlikely to be cost-effective compared with sorafenib for patients with unresectable HCC in the context of the USA and China. …”
Get full text