Human immunodeficiency virus prevention and testing strategies among men who have sex with men in the UK: the PANTHEON research programme including the SELPHI RCT by Janey Sewell, T Charles Witzel, David Dunn, Fiona Lampe, Fiona Burns, Peter Weatherburn, Sheena McCormack, Leanne McCabe, Alec Miners, Valentina Cambiano, Roger Pebody, Roy Trevelion, Nadia Hanum, Andrew Phillips, Alison Rodger

“…Modelling suggested that provision of oral tenofovir/emtricitabine pre-exposure prophylaxis increased human immunodeficiency virus testing, with anti-retroviral therapy initiation at diagnosis, and reductions in the level of condom-less sex, that each played an important role in decreasing human immunodeficiency virus incidence among men who have sex with men, and that the current human immunodeficiency virus incidence would have been double what it is if any one of them had not occurred. …”
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Advancing the therapeutic effectiveness of paclitaxel in chronic lymphocytic leukemia through the simultaneous inhibition of NOTCH1 and SF3B1 by Shiva Abolhasani, Armin Mahmoud salehi Khesht, Atefeh Khodakarami, Ali Masjedi, Bentolhoda Rashidi, Sepideh Izadi, Fatemeh Karimian Noukabadi, Vahid Karpisheh, Khatereh Torabi Poudeh, Pooya Jalali, Zahra Salehi, Rafieh Bagherifar, Seyyed Sina Hejazian, AliAkbar Movassaghpour, Abbas Ali Hosseinpour Feizi, Farhad Jadidi

“…Results Our findings showed that CL-NPs loaded with anti-NOTCH1/-SF3B1 siRNAs-PTX significantly suppressed NOTCH1 and SF3B1 expression in PBMCs and BMMCs isolated from CLL cases in comparison with the untreated samples, leading to increased leukemic cell sensitivity to PTX and decreased the proliferative capacity of leukemic cells. …”
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Optimized bio-signal reconstruction and watermarking via enhanced fractional orthogonal moments by Gaber Hassan, Khalid M. Hosny, Islam S. Fathi

“…The findings indicate that the proposed methodology exhibits significantly higher performance levels than current methodologies, with a 64.3% improvement in PSNR (reaching 147.08 dB compared to 89.74 dB in existing approaches), 89.7% reduction in MSE (0.0092 versus 0.09 average), and 84.1% decrease in bit error rate (0.25 versus 1.57) for watermarking applications. …”
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University students’ physical features- reasons, consequences, solutions by Cristiana Lucretia Pop, Viorela Popescu, Rela Ciomag, Cristina Filip, Cristina Nae

“…This study adds evidence to the limited literature investigating university students' attitudes, opinions, and contexts that contribute to a decrease in their physical potential. …”
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HORMONE IMBALANCE AS A MANIFESTATION OF STRESS IN THE FORMATION OF OLIGOMENORRHEA IN TEENAGE GIRLS by В. Диннік, О. Диннік, С. Новохатська

“…At OM onset, nearly 20% of participants exhibited low E2 levels. With increased disease duration (years 2–3), the proportion of adolescents with low E2 decreased while those with elevated E2 increased. …”
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Quantitative evaluation of essential amino acids and omega-3 long-chain polyunsaturated fatty acids from global marine bivalve aquaculture by Karsoon Tan, Peng Xu, Leiheng Huang, Cong Luo, KhaiHang Choong, Zexin Li, Yu Guo, Kit-Leong Cheong

“…Although many studies highlight bivalve aquaculture as a potential source of sustainable and high-quality proteins, there is limited quantitative data on the production of omega-3 long-chain polyunsaturated fatty acids (n-3 LC-PUFA) and essential amino acid (EAA) from global bivalve aquaculture. In this context, the present study aims to evaluate the current status of n-3 LC-PUFA and EAA production in global bivalve mariculture. …”
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Changing or validating physician opioid prescribing behaviors through audit and feedback and academic detailing interventions in primary care by Celia Laur, Natasha Kithulegoda, Nicola McCleary, Emily Nicholas Angl, Michael Strange, Barbara Sklar, Thivja Sribaskaran, Gail Dobell, Sharon Gushue, Jonathan M. C. Lam, Lindsay Bevan, Victoria Burton, Lena Salach, Justin Presseau, Laura Desveaux, Noah Ivers

“…Physicians mentioned that academic detailing validated current opioid practices or increased their belief about capabilities and their intentions , mediated by increased skills and the impact of environmental context and resources . …”
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Formation of the Soviet education system among the indigenous peoples of Southern Siberia in the 1920s by L. N. Aksenova, L. V. Sokolskaya, A. S. Valentonis, I. V. Shcherbinina

“…Today, the interest of researchers in regional history has increased all over the world; therefore, the current article will be useful to readers, as the analysis of new archival documents helps to fill the gaps in the scientific literature on the establishment of the Soviet school among the indigenous peoples of southern Siberia in the 1920s. …”
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Polymer carrier selection for creation of diosmin solid dispersion system by hot melt extrusion by A. A. Danilova, E. V. Vishnyakov, E. S. Surbeeva, K. A. Gusev, D. N. Maimistov, E. V. Flisyuk

“…Particular importance in the context of current approach is attached to the selection of an effective polymer matrix.Aim. …”
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Management system and optimal control for three-dimensional visualization and maintenance of thermal power plant by Zhiqiang Feng, Qiuxiang Liang, Mingyi Wei, Lei Li, Youzhu Bu, Yanqing Xin

“…After optimization by CNN technology, the response time of the system is increased by 5%. The calculation cost is reduced by 15%, and the data throughput is increased by 13%. …”
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From conflict to conservation: Understanding public attitudes of hunters and conservationists toward Carpathian lynx (Lynx lynx carpathicus) in Slovakia by Peter Smolko, Jakub Kubala, Peter Klinga, Tibor Lebocký, Rudolf Kropil, Ján Zbranek, Tomáš Iľko, Branislav Tám, Marek Svitok

“…Our data suggest that increasing public awareness of lynx, implementing adaptive science‐based management, and involving hunters in citizen science and management decisions might be the most effective way to develop policies balancing conservation goals with the socio‐cultural context of human‐large carnivore coexistence.…”
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Stakeholder perspectives on scaling up potassium-enriched salt to reduce cardiovascular disease in Australia: a qualitative study by Juliette Crowther, Annet C. Hoek, Kathy Trieu, Inez Denham, Irene Deltetto, Alain Balaguer-Mercado, James D. Bullen, Katrina Kissock, Dori Patay, Emalie Rosewarne, Simone Pettigrew, Bruce Neal, Jacqui Webster

“…Interviewees identified increased awareness, support for industry research and development, and leveraging current policies and initiatives (such as the Australian Health Star Rating system) as potential enablers. …”
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Burden of Diabetes Mellitus in Nepal: An Analysis of Global Burden of Disease Study 2019 by Achyut Raj Pandey, Krishna Kumar Aryal, Niraj Shrestha, Dikshya Sharma, Jasmine Maskey, Meghnath Dhimal

“…Globally, the number of people living with diabetes mellitus (DM) increased by 62% between 1990 and 2019, affecting 463 million people in 2019, and is projected to increase further by 51% by 2045. …”
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Pharmacokinetics of levosimendan in critically Ill children on extracorporeal membrane oxygenation: a prospective observational study by Stéphane Bertin, David Haefliger, Maria-Helena Perez, Monia Guidi, Monia Guidi, Laurent A. Decosterd, Vivianne Chanez, Ermindo R. Di Paolo, Thierry Buclin, Françoise Livio

“…This suggests that dosage should be increased in this context, to achieve optimal exposure of levosimendan and its active metabolite.…”
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Outcomes of COVID-19 on Patients with Cancer: A Scoping Review by Amjad Alrehaili, Samah Sofar, Duha Wazqar

“… Context: The COVID-19 pandemic has resulted in an unprecedented global health crisis. …”
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COVID-19 and Inflammatory Bowel Diseases: Risk Assessment, Shared Molecular Pathways, and Therapeutic Challenges by Iolanda Valentina Popa, Mircea Diculescu, Cătălina Mihai, Cristina Cijevschi-Prelipcean, Alexandru Burlacu

“…Conclusions. Using the current understanding of SARS-CoV-2 as well as other pathogenic coronaviruses immunopathology, we showed why IBD patients should not be considered at an increased risk of infection or more severe outcomes. …”
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Selection of Prosthesis in Aortic Valve Surgery: Short Review and Trend in our Practice in 10 Years by Selman Dumani, Ermal Likaj, Laureta Dibra, Devis Pellumbi, Adelina Musliu, Fjoralba Qejvani, Altin Veshti

“…This paper presents current issues regarding selecting aortic valve prostheses, considering factors related to the prosthesis and the patient. …”
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Fishing, offshore wind energy, climate change and marine spatial planning: Is it possible to plan for a best use of space? by Neda Trifonova, Beth E. Scott, Stephen C. L. Watson, Claire Szostek, Morgane Declerck, Nicola Beaumont

“…This perspective provides a methodology roadmap that considers the link between, and the need for, both food and energy security from our oceans and provides a route to increased certainty in our current choices for the long‐term sustainable use of our oceans.…”
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The Silent Burden of De Novo Metastatic Prostate Cancer in the Middle East: A Call for Region-Specific Screening Guidelines by Noura Abbas, Laudy Chehade, Zahi Abdul Sater, Ali Shamseddine

“…<b>Methods</b>: We conducted a comprehensive narrative review of epidemiological data on prostate cancer in the ME, examining trends in incidence and mortality, de novo metastatic cases, and current screening practices. Additionally, we assessed the applicability of international guidelines for prostate cancer screening to the ME context. …”
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Transformation of trading patterns in global agricultural markets by V. V. Stroev, E. N. Smirnov

“…The analysis of international trade is conducted in the context of the need to ensure food security and counteract various exogenous shocks (decreasing crop yields, escalating geopolitical conflicts, food crises). …”
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