Protecting the Autonomy of Patients with Severe Mental Illness Through Psychiatric Advance Directive Peer-Facilitation by Nicholas Karasik

“…Guiding Distributive Justice: Capability Theory Capability theory is an account of justice opportunity that places a fundamental moral significance on individuals' ability to reach proper functioning and well-being.[52] Whether or not an individual can make use of a particular set of resources and convert them into a state of functioning depends on personal, sociopolitical, and environmental conditions ("conversion factors").[53] In this sense, liberty is not the absence of restraint from others or institutions but the freedom achieved through capability-enhancing relationships.[54] Within the context of bioethics, capability theory shifts focus toward creating circumstances by which individuals can direct their lives as they choose.[55] Acting in accordance with the principle of beneficence, peer-support specialists could enhance the capability of patients to be self-determined and autonomous, which would promote patient well-being and empowerment.[56] Those living with SMI, such as schizophrenia and bipolar disorder, are among the most disadvantaged in society, experiencing social and economic hardship related to their illness.[57] These individuals are often feared and rejected by others, which increases depression, lowers self-esteem, and engenders feelings of social isolation.[58] Compounding their challenges, especially for those facing structural inequalities, is insufficient access to appropriate mental health services supporting recovery.[59] Capability theory provides a sound justification for the resource distribution necessary to create and sustain a thriving network of peer-support specialists, to which those with SMI currently do not have access. …”
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Prevalence and associated factors of tuberculosis among diabetic patients attending public health facilities in Ethiopia: a multicenter study by Ayinalem Alemu, Getachew Seid, Getu Diriba, Michael Hailu, Biniyam Dange, Shewki Moga, Daniel Melese, Gemechu Tadesse, Solomon H Mariam, Nega Berhe, Balako Gumi

“…Abstract Background Individuals with diabetes mellitus (DM) have high tuberculosis (TB) prevalence. Currently, the incidence of DM is increasing in low and middle-income countries including Ethiopia where TB is also endemic, which may complicate TB prevention and control efforts. …”
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Are they looking for support? Mental health and trauma awareness as predictors of mental health help-seeking behaviour among young adults and adolescents in Bangladesh, Egypt, Ghan... by Maxwell Peprah Opoku, Rahemeen Yusuf, Shakila Nur, Ebenezer Mensah Gyimah, Lilian Frimpomaa, Eleana Charalambous, Yasmin A. Salem, Mokhtar A. Elkayal, Aisha A. Abosrea, Tawasol Babiker, Mahra Murad Alblooshi, Erin September, Nada Obaid, Daniel Miezah, Ashraf Moustafa

“…This stagnation may be attributed to limited research on the underlying causes of mental health issues, such as trauma, as well as a lack of awareness regarding mental health disorders and help-seeking behaviours. The current study seeks to mainstream the understanding of mental health disorders by investigating the impact of trauma awareness and mental health disorders on the variance in help-seeking behaviours for mental health in non-Western contexts. …”
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Burnout in medical education: interventions from a co-creation process by Anke Boone, Lutgart Braeckman, Nele Michels, Kris Van den Broeck, Hanne Kindermans, Ann Roex, Marie-Claire Lambrechts, Sofie Vandenbroeck, Annabel Bijnens, Sofie Van den Acker, Sofie Boghe, Charlotte Vanneck, Dirk Devroey, Lode Godderis

“…While organisational interventions are increasingly recognized as crucial to address burnout, individual-focused interventions remain predominant in current research. …”
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High prevalence of the hotspot complement factor I p.Ile357Met pathogenic variant in Tunisian atypical hemolytic uremic syndrome patients: report of three new cases and review of t... by Asma Tajouri, Asma Tajouri, Asma Tajouri, Imen Ayadi, Imen Ayadi, Rimeh BenBrahim, Rimeh BenBrahim, Ikram Mami, Abir Boussetta, Hend Jlajla, Hend Jlajla, Yousr Zerzeri, Haifa Arbi Sassi, Jamila Ben Sassi, Hela Sahli, Lilia Laadhar, Lilia Laadhar, Tahar Gargah, Mohamed Karim Zouaghi, Maryam Kallel Sellami, Maryam Kallel Sellami

“…The recurrence of this variant in the Tunisian cohort led us to suggest that it could be characteristic of the Tunisian population.MethodsIn this context, we conducted the current study which included 8 adults and three children with suspected aHUS and decreased factor I levels, as well as one relative. …”
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Comparison of the indirect immunofluorescence assay and a commercial ELISA to detect KSHV antibodies by Valentin Leducq, Léa Ben Said, Sophie Sayon, Vincent Calvez, Anne-Geneviève Marcelin, Aude Jary

“…The current gold-standard method, the indirect immunofluorescence assay (IFA), has a very good specificity of close to 100%, but a lower sensitivity of around 80–85%, which decreases to 64–67% in immunocompromised patients. …”
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Research Status and Direction of Chronic Obstructive Pulmonary Disease Complicated with Coronary Heart Disease: A Bibliometric Analysis from 2005 to 2024 by Bian H, Zhu S, Xing W, Qi L, Xue J, Peng X, Jin Z, Zhao H

“…Through keyword clustering analysis, we categorized all keywords into three distinct groups: management strategies for COPD and CHD; diseases associated with both conditions; and epidemiological characteristics concerning their burden—current hotspots include multimorbidity factors such as hypertension and obesity alongside outcomes like diagnosis during COVID-19 pandemic implications within societal contexts are highlighted here too.Conclusion: Presently focused research on COPD coupled with CHD primarily revolves around five key areas: pathogenesis exploration, early diagnostic techniques, COVID-19 infection, dynamics intervention, methodologies, and treatment protocol development efforts. …”
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Blood transfusion training for prehospital providers: a scoping review by Pierre-Marc Dion, Kanwal Singh, Jillian Coleby, Andrew Beckett, Jacinthe Lampron, Melissa McGowan, Risa Shorr, Brodie Nolan

“…Abstract Background Blood transfusion is increasingly utilised to manage haemorrhagic shock in prehospital environments. …”
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Repetitive transcranial magnetic stimulation for the treatment of suicidality in opioid use disorder: a pilot feasibility randomized controlled trial by Victor M. Tang, Bernard Le Foll, Zafiris J. Daskalakis, An-Li Wang, Leslie Buckley, Daniel M. Blumberger, Daphne Voineskos

“…Conclusion We present the first data piloting a structural neuroimaging-guided, multi-session rTMS treatment course in outpatients with suicidality and OUD in the current North American context. Recruitment and retention were the main challenges given the highly unstable medical and psychosocial context of this patient population. …”
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Development of a Long-Acting Follicle-Stimulating Hormone Using Serum Albumin Fab-Associated Technology for Female Infertility by Daham Kim, Yoon Hee Cho, Min Jeong Kang, So Jeong Lee, Soohyun Lee, Bo Hyon Yun, Hyunjin Chi, Jeongsuk An, Kyungsun Lee, Jaekyu Han, Susan Chi, Moo Young Song, Sang-Hoon Cha, Eun Jig Lee

“…Conclusion These findings suggest that SAFA-FSH presents a promising alternative to current rhFSH treatments for female infertility. However, further research is essential to thoroughly assess its safety and efficacy in clinical contexts.…”
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A comprehensive item bank of internal validity issues of relevance to in vitro toxicology studies by Gunn E. Vist, Heather M. R. Ames, Gro H. Mathisen, Trine Husøy, Camilla Svendsen, Anna Beronius, Emma Di Consiglio, Ingrid L. Druwe, Thomas Hartung, Sebastian Hoffmann, Carlijn R. Hooijmans, Kyriaki Machera, Pilar Prieto, Joshua F. Robinson, Erwin Roggen, Andrew A. Rooney, Nicolas Roth, Eliana Spilioti, Anastasia Spyropoulou, Olga Tcheremenskaia, Emanuela Testai, Mathieu Vinken, Paul Whaley

“…Context In vitro toxicology studies are increasingly being included as evidence in systematic reviews and chemical risk assessments. …”
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Home Health Care Providers’ Readiness to Care for Children and Youth With Complex Medical Conditions: Protocol for a Scoping Review by Joanne Tay, Margaret Saari, Adam Mulcaster, Edward Cruz

“…However, families continue providing the bulk of care, often at great personal costs. As care complexity increases, so does the reliance on home care providers. …”
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Research status and prospects of treatment for malignant pleural mesothelioma by ZHAO Kaile, WANG Lei, GENG Jianxiong, CUI Chengwei, YU Yan

“…Malignant pleural mesothelioma (MPM) is strongly associated with a history of asbestos exposure and is characterized by high malignancy, high mortality, and poor prognosis. Current treatments for MPM are limited and generally suboptimal, resulting in a median overall survival (OS) of approximately one year for MPM patients. …”
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Student Mental Health in UK Higher Education Institutions: Protocol for a Scoping Review of Trends, Gaps, and Research Directions by Nicola Cogan, Aja Murray, Emily Long, Maria Gardani, Michelle O'Toole, Menchie Leung, Stella Kyratzi, Jelena Milicev, Katie Dryburgh, Chloe Bolota, Lacey Ho

“…Current literature remains fragmented, with limited synthesis comparing national contexts. …”
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The Bioethics-CSR Divide by Caio Caesar Dib

“…This includes investments, entrepreneurship models, and its relationship to stakeholders, leading to an increasing operationalization and globalization of the concept.[6] At first sight, these two movements seem to stem from different contexts. …”
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Artificial intelligence in Anatomy: Potential uses and challenges by Lubna Faisal

“…One more example of AI in anatomy teaching is ChatGPT. No doubt it increases students’ engagement, and ability to learn and has strong text analysis. …”
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Explorative Study of Modulatory Effects of Notochordal Cell‐Derived Extracellular Vesicles on the IL‐1β‐Induced Catabolic Cascade in Nucleus Pulposus Cell Pellets and Explants... by J. C. vanMaanen, F. C. Bach, J. W. Snuggs, K. Ito, M. H. M. Wauben, C. L. Le Maitre, M. A. Tryfonidou

“…Secretion of IL‐6 and C‐X‐C motif chemokine ligand 1 was significantly decreased in NC‐EV + IL‐1β vs. control+IL‐1β but not compared to EV‐depleted human explant controls. …”
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Assessment of the phenolic profile and biological activities of aqueous date seed extracts: A comparative analysis by Tareq M. Osaili, Aseel Swaidan, Anas Al-Nabulsi, Amin Olaimat, Susanne Neugart, Layla Engelhardt, Tuba Esatbeyoglu, Mutamed Ayyash, Leila Cheikh Ismail, Maher M Al-Dabbas, Reyad S. Obaid, Nada El Darra

“…Date palm fruit (Phoenix dactylifera L.) is a well-known fruit that has become increasingly popular among consumers due to its pleasant flavor, nutrient-dense content, and nutraceutical characteristics. …”
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A Framework for Cervical Cancer Elimination in Low-and-Middle-Income Countries: A Scoping Review and Roadmap for Interventions and Research Priorities by Michelle B. Shin, Gui Liu, Nelly Mugo, Nelly Mugo, Patricia J. Garcia, Patricia J. Garcia, Darcy W. Rao, Darcy W. Rao, Cara J. Broshkevitch, Linda O. Eckert, Linda O. Eckert, Leeya F. Pinder, Leeya F. Pinder, Judith N. Wasserheit, Judith N. Wasserheit, Judith N. Wasserheit, Ruanne V. Barnabas, Ruanne V. Barnabas, Ruanne V. Barnabas, Ruanne V. Barnabas

“…Using these data, we developed a logic model to summarize the current state of science and identified evidence gaps and priority research questions for each prevention strategy. …”
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Characterizing obesity: A qualitative study by Tim Bober, Flor Cameron, Lane Alexander, J.G. Luiggi-Hernandez, David Rometo, Linda-Marie Lavenburg, Haley Grant, Emily Klawson, Autumn R. Boyer, Kathleen M. McTigue, Julie Gouveia-Pisano, Avani Patel, Lisa Tarasenko, Jannette Escobar, Allison Brenner, Scott M. Vouri, Feng Dai, Megan E. Hamm

“…Conclusion: This qualitative study of people with obesity, health professionals, and payors demonstrated current views of addressing and treating obesity in clinical settings. …”
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