Towards ROXAS AI: automatic multi-species ring boundaries segmentation as regression in anatomical images by Marc Katzenmaier, Marc Katzenmaier, Vivien Sainte Fare Garnot, Jan Dirk Wegner, Georg von Arx, Georg von Arx

“…This will be another key step toward an AI-based version of the currently available ROXAS implementation.…”
Get full text

A multi-omic dissection of molecular hallmarks of accelerated aging in schizophrenia by DongDong Qi, Peng Liu, YiMeng Wang, XuGuang Tai, ShiFa Ma, Yue Wang

“…The intricate interplay of schizophrenia with the aging process is characterized by a shortened lifespan, underscoring the urgent need for an in-depth exploration of the underlying biological mechanisms that contribute to the unique aging trajectory within this specific patient population. Currently, this crucial aspect remains largely unexplored. …”
Get full text

Lemierre’s Syndrome Presenting with Multisystem Complications in a Child: A Case Report and Literature Review by Ashwaq AlEed

“…His recent medical history was unremarkable, except for decreased activity and oral intake over the past three days. …”
Get full text

Accounting conservatism and firm value in Egypt: the mediating role of tax avoidance by Yousra R. Obiedallah, Asmaa Hamdy Abdelaziz Mohamed El Mahdy

“…To strengthen the results of the three mediating GMM regression models, alternative deferred tax and current effective tax rate measures are utilized for tax avoidance. …”
Get full text

Large language model doctor: assessing the ability of ChatGPT-4 to deliver interventional radiology procedural information to patients during the consent process by Hayden L. Hofmann, Jenanan Vairavamurthy

“…Abstract Purpose The study aims to evaluate how current interventional radiologists view ChatGPT in the context of informed consent for interventional radiology (IR) procedures. …”
Get full text

Longitudinal host transcriptional responses to SARS-CoV-2 infection in adults with extremely high viral load. by Vasanthi Avadhanula, Chad J Creighton, Laura Ferlic-Stark, Divya Nagaraj, Yiqun Zhang, Richard Sucgang, Erin G Nicholson, Anubama Rajan, Vipin Kumar Menon, Harshavardhan Doddapaneni, Donna Marie Muzny, Ginger A Metcalf, Sara Joan Javornik Cregeen, Kristi Louise Hoffman, Richard A Gibbs, Joseph F Petrosino, Pedro A Piedra

“…Current understanding of viral dynamics of SARS-CoV-2 and host responses driving the pathogenic mechanisms in COVID-19 is rapidly evolving. …”
Get full text

Inequity Aversion Negatively Affects Tolerance and Contact-Seeking Behaviours towards Partner and Experimenter. by Désirée Brucks, Jennifer L Essler, Sarah Marshall-Pescini, Friederike Range

“…Results suggest that inequity aversion might in fact be mediated by simple emotional mechanisms: sharing a negative experience, like inequity, might reduce future cooperation by decreasing the likelihood of proximity being maintained between partners.…”
Get full text

Natural Alternatives in the Treatment of Colorectal Cancer: A Mechanisms Perspective by Karen Vanessa Fernandez-Muñoz, Cuauhtémoc Ángel Sánchez-Barrera, Marco Meraz-Ríos, Jose Luis Reyes, Eloy Andrés Pérez-Yépez, Maria Teresa Ortiz-Melo, Luis I. Terrazas, Monica Graciela Mendoza-Rodriguez

“…Curcumin, trimethylglycine, resveratrol, artemisinin, and some helminth-derived molecules, among others, are some natural compounds studied in the context of CRC. This review discusses the main benefits, mechanisms, advances, and dark side of conventional chemotherapeutics currently evaluated in CRC treatment. …”
Get full text

Early mental health intervention and supported self-care for LGBTQ+ young people in the UK: a mixed-methods study by Elizabeth McDermott, Rachael Eastham, Elizabeth Hughes, Emily Pattison, Katherine Johnson, Stephanie Davis, Steven Pryjmachuk, Ceu Mateus, Olu Jenzen, Felix McNulty

“…Stage 2: service mapping This stage of the study investigated and mapped current LGBTQ+ youth-specific mental health service provision across the UK. …”
Get full text

Kavalactones support motivation to move during intensive training in males preparing for military special operations forces by Sheena Y. Smith, Carlos F. Aylwin, Tyler F. Daniels, Jennifer L. Greer, Laura J. Kunces, Loukia Lili, Stephen M. Phipps, Caleb M. Schmidt, Julian C. Schmidt, Michael A. Schmidt

“…Furthermore, the group taking kavalactones first never experienced a significant decrease in Move motivation state (lowest mean score 21.0, highest 28.6, all p ≥ 0.05), while the group receiving kavalactones in the last 2 weeks of the study had Move scores that were statistically lower than baseline (lowest mean score 8.6, highest 25.9, all p ≤ 0.05) at all time points but the last (p = 0.063) after 2 weeks of kavalactones exposure.Conclusions We report a novel finding that kavalactones may support performance by maintaining or rescuing the desire to expend energy in the context of significant physical and mental strain in well-conditioned individuals, even in a context of already normal cortisol, sleep, and mood.…”
Get full text

Direct oral penicillin challenge in secondary care with low-risk patients: the SPACE mixed-methods study with cost-effectiveness analysis by Mamidipudi Thirumala Krishna, Yogini H Jani, Iestyn Williams, Ruben Mujica-Mota, Rebecca Bestwick, Michele Siciliano, Robert Michael West, Rashmeet Bhogal, Bee Yean Ng, Kornelija Kildonaviciute, Rachel Pollard, Nicola Jones, Louise Dunsmure, Mairead McErlean, Neil Powell, Chidanand C Hullur, Ariyur Balaji, Jonathan Sandoe, Amena Warner, Ron Daniels, Caroline Thomas, Siraj A Misbah, Louise Savic

“…Penicillin allergy labels lead to increased risk for serious hospital infections and longer hospital stay and are associated with higher estimated healthcare costs. …”
Get full text

Advances in technology for seed germination of bamboo species by Anca Awal Sembada, Ristag Hamida Hanisia, Yuliar Yuliar, Yayat Hidayat, Ihak Sumardi

“…We systematically compile and evaluate current methodologies and identify the effective technologies in different environmental contexts. …”
Get full text

Analysis of Factors Influencing the Development of Community-Based Tourism in Rural Areas, Case Study: Villages Targeted by Tourism in the Markazi Province by Hamid Afshari, Behrouz Mohammadi Yeganeh, Hossein Farahani, Mehdi Cheraghi

“…In the socio-cultural dimension, it should be said that there is a strong relationship between cultural sustainability and participation, and the local community is very vulnerable to the indiscriminate and unprincipled increase in tourism. The results of the current research showed that due to the lack of correct and principled planning in all dimensions, including the cultural dimension, the participation of the local community in tourism was very small. …”
Get full text

A group psychological intervention for postnatal depression in British mothers of South Asian origin – the ROSHNI-2 RCT by Nusrat Husain, Karina Lovell, Carolyn A Chew-Graham, Farah Lunat, Penny Bee, Matthias Pierce, Najia Atif, Saadia Aseem, Kamaldeep Bhui, Peter Bower, Traolach Brugha, Nasim Chaudhry, Akbar Ullah, Linda Davies, Nadeem Gire, Deepali Sharma, Jahanara Miah, Waqas Ahmed, Joe Kai, Ilyas Mirza, Jillian Morrison, Naeem Mohmed, Atif Rahman, Shanaya Rathod, Najma Siddiqi, Waquas Waheed, Christopher Williams, Nosheen Zaidi, Richard Emsley, Richard Morriss

“…An additional substudy was incorporated following the pandemic to explore the impact of other associated risk factors related to maternal mental health and specifically in the pandemic’s context. We aimed to increase the understanding of the pandemic-related impact on BSA women, including interpersonal violence (IPV) in their communities. …”
Get full text

How STEM content is presented in mathematics textbooks from the U.S. and China: a comparative study by Shuhui Li, Lianghuo Fan, Jietong Luo

“…The PEP series contained more from engineering and agriculture, and presented more in the main text; the BIM series presented more in statistics and probability, placed more in chapter previews, had more moderate-level content (i.e., partial integration of content knowledge) and a balanced distribution of authentic and non-authentic contexts in enriched-level content. Conclusion and implications The current STEM content, especially those at enriched-level, is limited. …”
Get full text

Microalgae-based dosimetry for monitoring blue light exposure by Léa Habib, Jihane Rahbani Mounsef, Rime Michael-Jubeli, Marie Abboud, Ali Tfayli, Roger Lteif

“…Blue light therapy is increasingly used to treat various skin conditions like acne, psoriasis and neonatal hyperbilirubinemia. …”
Get full text

Patterns of childhood trauma co-occurrence and its predictivity for suicidality: A machine learning approach by Wenbang Niu, Yi Feng, Shicun Xu, Xin Cui, Zhihao Ma, Yuanyuan Wang

“…The relationship between different CT patterns and suicidality remains largely undiscovered. The current study aims to identify distinct CT overlapping patterns and to explore their association with suicidality in a comprehensive multivariable context. …”
Get full text

Le réseau hydraulique à Pompéi (Italie) de l’époque des Samnites à Auguste (fin ive-fin ier s. av. J.-C.) by Federico Giletti

“…While the latter type appears equally in both private and public contexts, the burrow cistern by contrast differs in that it is excavated entirely into the lava stratum and has been demonstrated, as far as we currently know, only on the main outcrops of the lava plateau, such as on the rocky crest of the southern drop in height below insula 2 of Regio VIII.While the type of cistern with a burrow or bainhole seems to have been inspired by models already widespread in Punic-Carthaginian sites in Africa and on the islands and in the Magna-Greek area, cases of cisterns with a burrow collected to several arms primarily bear strong similarities to Etruscan-Latian examples, as does the technique of drainage tunnels entirely excavated in the geological bank and the custom of digging deep artesian wells. …”
Get full text

Dissociative Identity Disorder: A Comprehensive Review of Etiology, Diagnosis, Neurobiology, and Treatment by Monika Fidyk, Michał Bolek, Bartosz Jagieła, Aleksandra Kędzia, Dominika Musialska, Magda Minkiewicz

“…While debates surrounding the validity and origin of DID continue—particularly regarding the trauma model—empirical findings increasingly affirm the disorder’s legitimacy. Simulation of DID remains a concern, especially in forensic contexts, yet validated psychological and physiological assessments can aid in differential diagnosis. …”
Get full text

Developing Multi-Modal Communication Tools for Retrofit Guidance in Ageing Bushfire-Prone Communities by Shuang Wu, Mona Salam, Aso Hajirasouli, Iina Lohi, Alison Wain, Sara Wilkinson, Gregory M. Morrison, Saeed Banihashemi

“…The increasing frequency and severity of bushfires in Australia, combined with an ageing population in bushfire-prone regions, creates an urgent need for targeted resilience guidance for older Australians. …”
Get full text