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3281
Immune factors and their role in tumor aggressiveness in glioblastoma: Atypical cadherin FAT1 as a promising target for combating immune evasion
Published 2025-07-01“…In addition, FAT1 promotes an immunosuppressive microenvironment in glioblastoma, reducing T-cell and monocyte infiltration while increasing immunosuppressive cells such as MDSCs. It also upregulates pro-inflammatory mediators [cyclooxygenase-2 (COX-2), interleukin-1β (IL-1β), and interleukin-6 (IL-6)], fostering tumor-promoting signaling. …”
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3282
Phagocytic function of tumor-associated macrophages as a key determinant of tumor progression control: a review
Published 2020-10-01“…The rationale for increasing TAM phagocytic activity is to improve innate anticancer immunity, and to promote T-cell mediated adaptive immune responses. …”
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3283
Advancements and Challenges in the Management of Prosthetic Valve Endocarditis: A Review
Published 2024-11-01“…It is a significant concern in the field of cardiology, and the epidemiology of PVE has seen notable developments over the last five decades. The disease currently affects an older demographic and is becoming increasingly prevalent in patients with transcatheter-implanted valves. …”
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3284
Leveraging agent-based modeling and a randomized intervention to advance childhood physical activity: A study protocol.
Published 2025-01-01“…Successful early childhood PA interventions can potentially play an important role in both increasing overall population health as well as closing health disparities across subpopulations. …”
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3285
The role of judicial authorities in criminal proceedings for political crimes in the Stalinist period: modern historiography
Published 2019-11-01“…A number of works on the history of the judicial authorities contain sections on the application of the rules of judicial procedure to political crimes. Currently, PhD theses, covering an increasing number of regions of Russia, are being defended actively. …”
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3286
Impact on alcohol selection and online purchasing of changing the proportion of available non-alcoholic versus alcoholic drinks: A randomised controlled trial.
Published 2023-03-01“…<h4>Background</h4>Increasing the availability of non-alcoholic options is a promising population-level intervention to reduce alcohol consumption, currently unassessed in naturalistic settings. …”
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3287
An Mcformer encoder integrating Mamba and Cgmlp for improved acoustic feature extraction
Published 2025-07-01“…Abstract Currently, attention models based on the Conformer architecture have become mainstream in the field of speech recognition due to their integration of self-attention mechanisms and convolutional networks. …”
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3288
The Lack of Researchers: A Critical Threat to Studies on Freshwater Zooplankton in Latin America
Published 2025-05-01“…The scarcity of researchers working on freshwater zooplankton currently threatens the future of these studies in the world. …”
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3289
The impact, perceptions and needs of parents of children with epidermolysis bullosa
Published 2024-06-01“…Addressing parents’ needs and concerns will go a long way in decreasing this burden. A biopsychosocial approach with an awareness of cultural context is essential for family-centred holistic EB care. …”
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3290
ANALYSIS OF THE PERSONNEL’S CONSISTENT READINESS FOR CHANGES AS ILLUSTRATED BY THE EXAMPLE OF AN EXPORT-ORIENTED BIOTECHNOLOGICAL ENTERPRISE
Published 2021-12-01“…The biotechnology industry is currently one of the most dynamically developing sectors of the pharmaceutical industry, that is why it requires improvement in the personnel management system aimed at increasing the flexibility and adaptability of the organization.The aim of the research is to determine the degree of readiness of the organization’s employees for innovations as illustrated by the example of an export-oriented enterprise.Materials and methods. …”
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3291
Development of a Best Practice Guide to Optimise the Reporting of Patient Reported Measures by Clinical Quality Registries for Quality Improvement Purposes
Published 2025-08-01“…A preliminary BPG was refined during the workshop discussions. Conclusion: An increasing number of CQRs use PRMs to enhance QI reporting, however there are no published guidelines currently to support this. …”
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3292
Acute Effects of a Single-Bout Session of High-Intensity Functional Training and Moderate-Intensity Functional Training on Cognitive Functions, Anxiety, and Stress in Healthy Adult...
Published 2025-01-01“…Background: Currently, it has been observed that a fast-paced lifestyle, along with factors such as work pressure and economic and political uncertainty, among others, negatively impacts cognitive functions and increases levels of anxiety and stress in the population. …”
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3293
Conceptualización de los medios sociales: oportunidades para la gestión del deporte (Conceptualisation of Social Media: opportunities for Sport Management)
Published 2019-07-01“…Social Media is a phenomenon that is changing the way that people communicate and relate among others, with many millions of users around the world. In the context of Sport Management, Social Media currently is playing a role increasingly more relevant in the day to day of clubs, athletes, federations, companies, researchers, etc. …”
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3294
Identifying Patient-Reported Care Experiences in Free-Text Survey Comments: Topic Modeling Study
Published 2025-02-01“…As the use of patient experience measurement increases in health care, we discuss how machine learning can be leveraged to provide additional insight on patient experiences.…”
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3295
Anesthetic problems in concomitant systemic lupus erythematosus (literature review)
Published 2025-04-01“…Based on available literature sources, we have analyzed the impact of systemic lupus erythematosus (SLE) on organs and body systems, the main pathological aspects of the interaction of dosage forms used for its treatment with anesthetic drugs for the purpose of increasing the anesthetic safety of such patients during surgical interventions. …”
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3296
Psychological predictors and “protectors” of students’ Internet addiction
Published 2022-05-01“…Introduction. Currently, in the context of the COVID-19 pandemic, the educational environment is forced to “migrate” to a virtual environment, which significantly increases the duration of student youth on the Internet space. …”
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3297
A comprehensive review of methodologies and application to use the real-world data and analytics platform TriNetX
Published 2025-03-01“…TriNetX’s federated network architecture allows real-time, privacy-compliant data access, significantly enhancing the ability to conduct retrospective studies and refine clinical trial designs. With access to currently over 150 million EHRs, TriNetX has proven particularly effective in filling gaps left by RCTs, especially in the context of rare diseases, rare endpoints, and diverse patient populations. …”
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3298
Where Has All the R-process Gone? Timescales for Gamma-Ray Burst Kilonovae to Enrich Their Host Galaxies
Published 2025-01-01“…Neutron star (NS) mergers are currently the only observed source of r -process production in the Universe. …”
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3299
The limited contribution of local food policies in food resilience: The case of French Territorial Food Projects
Published 2025-04-01“…The concept of resilience is currently increasingly used to investigate how food systems operate. …”
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3300
Implementing nature walking groups in mental health services as a transdiagnostic approach to promote recovery: a study protocol for a non-randomised trial
Published 2025-08-01“…Abstract Background Australia is currently facing substantial challenges due to the increasing prevalence of mental health disorders, which pose significant burden on the healthcare system. …”
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