P22 | EXPLORING THE UNEXPECTED DUAL ROLE OF GARLIC DERIVATIVES IN REGULATING INVASIVENESS IN BREAST CANCER SUBTYPES

“…However, studies fail to account for the high heterogeneity within triple-negative breast cancer (TNBC), and no data are currently available about its effects on HER2+ tumors, which, despite recent therapeutic advances, frequently develop resistance. …”
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Longitudinal analysis of local government spending on adult social care and carers’ subjective well-being in England by Yanan Zhang, Matthew R Bennett, Sue Yeandle

“…Objectives Reform of England’s social care system is repeatedly discussed in the context of increasing demand, rising costs and austere policies that have decreased service provision. …”
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Advances in Wearable Sensors for Learning Analytics: Trends, Challenges, and Prospects by Huaqing Hong, Ling Dai, Xiulin Zheng

“…Wearable sensor technology is increasingly being integrated into educational settings, offering innovative approaches to enhance teaching and learning experiences. …”
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Nonhistone Lysine Methylation as a Protein Degradation Signal by Nicholas A. Lehning, Brad E. Morrison

“…As such, there has been increasing interest in lysine methylation and associated lysine methyltransferases (KMTs), beyond canonical histone protein modification, in mediating protein degradation in a variety of contexts. …”
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Acquisition of –Ing in English by Multilingual Adult Speakers in Germany and the US by Gulumser Efeoglu

“…The current study aims at investigating multilingual speakers’ spoken and written English productions in formal and informal contexts within the boundaries of social context of migration. …”
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Warming Permafrost in the Western Alps: A Further Evidence of Elevation Dependent Warming? by Paolo Pogliotti, Edoardo Cremonese, Umberto Morra di Cella

“…The dataset includes monitoring sites located at different altitudes and geomorphological contexts such as rock walls, high-altitude plateau and proglacial margins.The results show that the thickness of the active layer is increasing everywhere and that anomalies are consistent between sites despite their different characteristics and distances. …”
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Climate anxiety in early childhood: A state-of-the-art review by Jane Spiteri

“…As the climate crisis intensifies, young children are increasingly exposed to psychological stress linked to environmental change, manifesting in emerging forms of anxiety, sadness, and guilt. …”
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A systematic review on search‐based test suite reduction: State‐of‐the‐art, taxonomy, and future directions by Amir Sohail Habib, Saif Ur Rehman Khan, Ebubeogu Amarachukwu Felix

“…The study's main objective is to examine and classify the current state‐of‐the‐art approaches used in search‐based TSR contexts. …”
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Computational markers show specific deficits for dyslexia and ADHD in complex learning settings by Yafit Gabay, Lana Jacob, Atil Mansour, Uri Hertz

“…Abstract The current study examined how individuals with neurodevelopmental disorders navigate the complexities of learning within multidimensional environments marked by uncertain dimension values and without explicit guidance. …”
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Analysis of world trends in soybean production by Volkova Elena, Smolyaninova Natalia

“…The paper analyzes the dynamics and structure of sown areas, gross harvest volumes and soybean yields in the world for the period 2014- 2023 in the context of leading producing countries. The increase in sown areas and increased yields ensures the growth of global soybean production. …”
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Towards Non-Animal Testing in European Regulatory Toxicology: An Introduction to the REACH Framework and Challenges in Implementing the 3Rs by Katerina Stoykova

“…Key challenges identified include contradictory and inadequate legislative frameworks, slow and restrictive validation processes, low acceptance of NAMs by regulatory authorities, and legislative amendments expected to increase animal testing. To create a more flexible regulatory environment and advance the adoption of NAMs, there is a need for legislative reforms and increased collaboration between academia, industry and regulatory bodies. …”
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BUILDING ENVIRONMENTAL AWARENESS AMONG STUDENTS IN POLAND – CASE STUDY WROCŁAW UNIVERSITY OF SCIENCE AND TECHNOLOGY by Magdalena WĘGLARZ

“…Generation Z, current university students, has demonstrated a notable increase in environmentally conscious actions and attitudes. …”
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The Immune Environment in Colorectal Adenoma: A Systematic Review by Ugne Silinskaite, Jurate Valciukiene, Matas Jakubauskas, Tomas Poskus

“…<b>Methods:</b> In this systematic review, we aim to provide a thorough analysis of the current research examining the immune infiltration patterns in sporadic colorectal adenoma tissues in the context of immune cell-based, cytokine-based, and other immunological factor-related changes along the conventional adenoma–carcinoma sequence. …”
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The influence of entrepreneurial role model on entrepreneurial intention: a cross-level investigation by Mu Xuan, Liu Yankai

“…Social implications – At the same time, role models should be presented differently in diverse cultural contexts. For example, in countries with a strong collectivist orientation, the media should include collectivist messages when promoting entrepreneurial role models, such as his cooperation with the government, family and friends, which is in line with collectivist values, so that potential entrepreneurs in a collectivist context may perceive more similarity to role models and thus increase their entrepreneurial intentions (Morris et al., 1994); On the contrary, in countries with low collectivist tendencies, the media can appropriately carry an element of individualism when promoting entrepreneurial role models, for example, by telling how entrepreneurs succeed on their own strength and superior abilities, which is in accordance with the values of individualism. …”
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Development of a Long-Acting Follicle-Stimulating Hormone Using Serum Albumin Fab-Associated Technology for Female Infertility by Daham Kim, Yoon Hee Cho, Min Jeong Kang, So Jeong Lee, Soohyun Lee, Bo Hyon Yun, Hyunjin Chi, Jeongsuk An, Kyungsun Lee, Jaekyu Han, Susan Chi, Moo Young Song, Sang-Hoon Cha, Eun Jig Lee

“…Conclusion These findings suggest that SAFA-FSH presents a promising alternative to current rhFSH treatments for female infertility. However, further research is essential to thoroughly assess its safety and efficacy in clinical contexts.…”
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Stress and influencing factor among children diagnosed with cancer at hospitals in Nepal: a cross-sectional study by Surya Kamal Shahi, Panpan Wang, Jinjin Gu, Rajendra Man Shrestha, Peng Wang

“…The linear regression model showed that stress is associated with socio-demographic variables sex in which female children are more stressed (β = 1.750 (95% CI: 0.46, 3.03) P < 0.05) and clinical features duration of diagnosis as the time increase (12 < Month ≤ 24) level of stress decreased (β =-1.730 (95% CI: -3.20,-0.25) P < 0.05. …”
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Theoretical Research on the Shear Mechanical Properties and Size Effect of Recycled Concrete Beams Without Stirrups by Chunyang Liu, Guangkai Zhou, Hao Wang, Yilin Wang

“…As a new type of building material with great potential, recycled concrete is playing a vital role in the context of the current construction industry’s pursuit of sustainable development. …”
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Redefining luxury: exploring the natural connection with sustainability beyond labels by Nermain Al-Issa

“…This trend holds across diverse cultural contexts. Nevertheless, insights from this study highlight the importance of considering cultural differences, particularly in social motives, in the context of luxury and sustainability.Originality The current research adds to the understanding of the self-congruity concept, which influences consumers’ evaluation of products based on how they relate product or brand values to their self-identity. …”
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Enhanced recovery pathway for older people with hip fracture and cognitive impairment in acute hospitals: the PERFECTED research programme including an RCT by Chris Fox, Simon P Hammond, Lee Shepstone, Fiona Poland, Catherine Henderson, Tamara Backhouse, Bridget Penhale, Simon Donell, Martin Knapp, Douglas Lewins, Alasdair MacLullich, Martyn Patel, Opinder Sahota, Toby O Smith, Justin Waring, Jane L Cross

“…In the 12 months after fracture, patients are at increased risk of cognitive and functional decline, admission to long-term care institutions and higher mortality. …”
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Quality improvement project to improve cardiovascular risk screening in patients with rheumatoid arthritis by Mireille Edens, Monique Hoekstra, Harriet de Vries, Clarinda van den Bosch-Schreuder

“…The CV risk screening in the Netherlands is performed by the general practitioner (GP).Purpose The aim of our project was to increase the CV risk screening of patients with RA, performed by the GP, from 46% to 65% of the selected patients of 40 years and older, within the time frame of our project (18 months).Context The project was carried out at the outpatient rheumatology clinic at Isala Zwolle, a large teaching hospital, in an area with 106 GP practices. …”
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