Mechanical Load‐Induced Upregulation of Talin2 through Non‐Canonical Deubiquitination of OTUB1 Drives Facet Joint Osteoarthritis Pathogenesis by Yizhen Huang, Heng Sun, Haojie Chen, Xiangpeng Wang, Junduo Zhao, Yang Jiao, Hongyi Zhou, Haoyu Cai, Jiafeng Dai, Xuan Huang, Weiyun Chen, Jianxiong Shen

“…Abstract Facet joint osteoarthritis (FJOA) is a prevalent degenerative condition in the aging population; however, the underlying pathophysiological mechanisms remain poorly understood and current therapeutic strategies remain limited to palliative pain management. …”
Get full text

Climate change reduces warming potential of nitrous oxide by an enhanced Brewer‐Dobson circulation by Daniela Kracher, Christian H. Reick, Elisa Manzini, Martin G. Schultz, Olaf Stein

“…N2O is a potent greenhouse gas and the most relevant currently emitted ozone‐depleting substance. Here we examine the implications of a reduced N2O lifetime in the context of climate change. …”
Get full text

The Link between Ankylosing Spondylitis, Crohn’s Disease, Klebsiella, and Starch Consumption by Taha Rashid, Clyde Wilson, Alan Ebringer

“…Hence, a decrease of starch-containing products in the daily dietary intake could have a beneficial therapeutic effect on the disease especially when used in conjunction with the currently available medical therapies in the treatment of patients with AS and CD.…”
Get full text

Analysis of clinical and epidemiological interactions of phenol and phthalate levels in blood and urine with anamnestic and biochemical health measures during the formation of mult... by I. Yu. Torshin, O. A. Gromova, T. E. Bogacheva, A. N. Gromov

“…This confirms the correlation between smoking and increased concentrations of phenol and its derivatives.Conclusion. …”
Get full text

Development of standard samples-simulators of weight fraction of acetone insoluble substances in rapeseed lecithins by O. S. Agafonov, E. V. Lisovaya, S. M. Prudnikov, E. P. Victorova

“…Currently, there is an increase in the volume of rapeseed processing, which leads to a natural increase in the production of by-products such as rapeseed lecithin. …”
Get full text

Synthesis of magnetite nanoparticles using electrochemical oxidation by Ye. Ya. Levitin, I. D. Roy, O. S. Kryskiv, T. M. Chan

“…The rate of this process increases at potentials higher than 1.3V, which is associated with the passage adjacent the reduction reaction of water to oxygen. …”
Get full text

Blend of low cost electrode material for energy storage device under DC glow discharge plasma exposed ESAC by Vijayalakshmi K.A, Judith Fennila, K T Maheswari

“…More oxygen-containing functional groups are present, according to an FTIR analysis. …”
Get full text

Stunting Super App as an Effort Toward Stunting Management in Indonesia: Delphi and Pilot Study by Kadek Ayu Erika, Nur Fadilah, Aulia Insani Latif, Nurhikmawaty Hasbiah, Aidah Juliaty, Harun Achmad, Anugrayani Bustamin

“… Abstract BackgroundCurrently, 30 million children are experiencing acute malnutrition, and 8 million children are severely underweight. …”
Get full text

Development of recipes for combined products with functional properties by O. A. Ogneva, N. S. Bezverkhaya

“…Currently, products with functional properties are becoming more and more important, therefore, it is relevant to expand the range of these products and increase their production. …”
Get full text

Leasing impact on transformation processes in the Russian agricultural sector under sanctions pressure by A. A. Kiritsa, Yu. V. Chutcheva

“…With consideration to  the current situation in   the domestic market, decreased prices for agricultural products and rapid growth of   prices for agricultural machinery, the most promising areas for the use of  leasing mechanisms have been proposed to   help accelerate technical re-equipment in   the agricultural sector: application of   leasing solutions in   the agricultural industry that have already been tested and proven successful in   other market segments (for example, subscription, agrocarsharing, etc.); combination of   leasing mechanisms with trade-in programmes which make it  possible to  comprehensively solve issues not only of   updating machinery and tractor fleet, but also of  recycling worn-out agricultural equipment; use of   leasing mechanisms for the development of  machine and technological complexes as a   modern form of  joint use of   machinery in  agriculture which allows accelerating technical equipment of   the industry. …”
Get full text

Development of Lentil Aquafaba-Based Food Emulsions with Xanthan Gum or Pregelatinized Corn Starch as Stabilizers by Valentyna Dehtiar, Anastasiia Sachko, Anna Radchenko, Olha Hrynchenko, Sergey Gubsky

“…Currently, there is an increasing trend towards the use of legumes aquafaba-based emulsions for food applications. …”
Get full text

LRRC8A in endothelial cells contributes to the aberrant blood-brain barrier integrity in ischaemic stroke by Yan Wang, Yan Zhang, Chang Liu, Xiaoyu Zhang, Bo Wang, Yue Kong, Hailin Zhang, Yanfei Tian, Yupeng Zhao, Zhenghui Wu, Huaxing Zhang, Xiaona Du, Huiran Zhang

“…Background The increased permeability of the blood-brain barrier (BBB) is a critical contributor to the high mortality following ischaemic stroke. …”
Get full text

Exploration of the breast ductal carcinoma in situ signature and its prognostic implications by Jiao Zhang, Hui Lin, Lei Hou, Hui Xiao, Xilong Gong, Xuhui Guo, Xuchen Cao, Zhenzhen Liu

“…Abstract Following the implementation of breast screening programs, the occurrence of ductal carcinoma in situ (DCIS) as an early type of neoplasia has increased. Although the prognosis is promising, 20%–50% of DCIS patients will progress to invasive ductal carcinoma (IDC) if not treated. …”
Get full text

Wear-resistant Ti/TiCp composite coatings via synchronous powder supplied wire arc additive manufacturing by Xinxin Guo, Ming Ma, Shuaifeng Zhang, Zhengying Wei

“…As the current increases, the number of in-situ primary TiC grains in the matrix increases, and many coarse dendritic structures can be observed. …”
Get full text

M.A.R.V.E.L.S. "Medical Students Advancing Research, Visibility, Education, Leadership, and Support." A Student-Driven Initiative by Molly Mehta, Kayvon Yazdanbakhsh, Elizabeth Hsu, Olga Gomeniouk, Kayla Nenninger, Devin P. Asher

“…METHODS: A committee of six second-year medical students and four faculty advisors established three networks to increase medical student involvement in research. The first is a Microsoft systems database containing contact, field of study, productivity, and project information of research faculty open to mentoring students aimed to facilitate meaningful collaboration between faculty seeking help with research projects and medical students eager to conduct research. …”
Get full text

Contribution of the TRPM4 Channel to Osteogenic Differentiation of Human Aortic Valve Interstitial Cells by Margaux Aize, Arthur Boilève, Benoit D. Roussel, Laura Brard, Harlyne Mpweme Bangando, Corentin Kerevel, Alexandre Lebrun, Hind Messaoudi, Vladimir Saplacan, Alain Manrique, Romain Guinamard, Christophe Simard

“…Results Western blot on VICs revealed TRPM4 protein expression and channel functionality was confirmed by patch‐clamp recordings exhibiting a cationic current sensitive to voltage and internal Ca2+. VICs maintained in pro‐calcifying media exhibited a higher mineralization than in standard media, with an increase in osteogenic markers. …”
Get full text

Effects of pharmacological and non-pharmacological interventions for the management of sleep problems in people with fibromyalgia: a multi-methods evidence synthesis by Mari Imamura, Clare Robertson, Jemma Hudson, Daniel Whibley, Lorna Aucott, Katie Gillies, Marcus Beasley, Martin J Stevens, Paul Manson, Debra Dulake, Abhishek Abhishek, Nicole KY Tang, Gary J Macfarlane, Miriam Brazzelli

“…However, heterogeneity, imprecision and low quality of the current evidence base preclude any firm conclusions. …”
Get full text

Automated Mapping of the Freshwater Ecosystem Functional Groups of the International Union for Conservation of Nature Global Ecosystem Typology in a Large Region of Arid Australia by Roxane J. Francis, Hedley S. Grantham, David A. Keith, Jose R. Ferrer-Paris, Richard T. Kingsford

“…The classification of freshwater ecosystems is essential for effective biodiversity conservation and ecosystem management, particularly with increasing threats. We developed an automated approach to mapping and classifying freshwater ecosystem functional groups based on the IUCN Global Ecosystem Typology (GET), offering a scalable, dynamic and efficient alternative to current manual methods. …”
Get full text

Ozonolytic synthesis of 2-hydroxybenzyl alcohol for the production of gastrodin by A. H. Halstian, A. S. Hasanova, H. V. Tarasenko

“…Continuous monitoring of the current concentration of ozone, with the recording of the analysis results in the form of a kinetic curve, was carried out when ozone-containing gas passed through the curette at a certain wavelength of a monochromatic light source. …”
Get full text

Differences between the European and Eurasian Good Pharmacovigilance Practices by A. V. Matveev, A. E. Krasheninnikov, E. A. Matveeva, B. K. Romanov

“…However, the number of differences between the documents increases, as changes are made to the EU GVP. A more comprehensive harmonisation of the EAEU GVP with the current version of the EU GVP will make it possible to develop and use uniform pharmacovigilance documents in the EU and EAEU, and will facilitate the introduction of EAEU medicines into the global pharmaceutical market.…”
Get full text