Arginine–NO pathway modulated energy metabolism in the hepatopancreas and muscle of female Litopenaeus vannamei by Haitao Fan, Xin Zhang, Yanan Yin, Lefei Jiao

“…Currently, the regulational effect of arginine on the energy metabolism is unknown in broodstock shrimp nutrition. …”
Get full text

Optimal dietary vitamin E level facilitates ovarian development of female largemouth bass (Micropterus salmoides) broodstock by Qiuyu Gao, Qiao Feng, Dong Zhou, Zhili Ding, Changle Qi, Youqin Kong, Qiyou Xu

“…The current study was designed to explore the effects of dietary vitamin E on the ovarian development and health of female largemouth bass (Micropterus salmoides). …”
Get full text

Combustion and Emission Characteristics of Methanol–Diesel Dual Fuel Engine at Different Altitudes by Zhongcheng Wang, Zhu Jie, Xiaoyu Liu

“…Currently, in the two technological approaches for using diesel pilot injection to ignite methanol and partially substituting diesel fuel with methanol, neither can fully achieve carbon neutrality in the context of internal combustion engines. …”
Get full text

Brain Imaging Findings in Dyslexia by Ying-Fang Sun, Jeun-Shenn Lee, Ralph Kirby

“…Reduced hemispheric asymmetry and increased left inferior frontal activation were reported following magnetoencephalography. …”
Get full text

Comparison and theoretical conceptualization analysis of statistical methods used to develop heat vulnerability indices in urban areas by Thomas Lagelouze, Julia Hidalgo, Mitia Aranda, Guillaume Dumas

“… In view of the impact of extreme temperatures on physical and psychological health, particularly in urban areas, several studies have focused on assessing social vulnerability using quantitative indexing approaches with the aim of creating a heat vulnerability index (HVI). In this context, this study employs three statistical methodologies frequently used to construct HVIs on the territory of the Toulouse Métropole, France, at the census block (IRIS) scale to assess the efficiency of this type of approach for evaluating social vulnerability in urban environments considering the current theoretical conceptualization. …”
Get full text

الطريقة القادرية الشاذلية كمنهج الدعوة الإسلامية لمعهد "منهل الناشئين" الإسلامي by Nurul Hayati

“…Today the Muslim community in the capital of Indonesia seem to experience decadency, especially in terms of ethics, manners, association, lifestyle and care for fellow Muslim people who are increasingly indifferent. Another negative impact that is very concerning is the change that tends to lead to a moral crisis in Muslim society today, especially in the younger generation, such as the phenomenon of a free lifestyle, television broadcasts containing films that provoke the Muslim to date, pornography and porn-action. …”
Get full text

Examining the longitudinal associations between activity limitations, instrumental supports and social participation in osteoarthritis: A CLSA population-based study. by Anthony V Perruccio, Calvin Yip, J Denise Power, Mayilee Canizares, Elizabeth M Badley

“…<h4>Objective</h4>In osteoarthritis (OA) research, disability is largely studied within the context of activities of daily living. Broader consequences for social participation are often overlooked. …”
Get full text

Introducing the non-invasive prenatal test for trisomy 21 in Belgium: a cost-consequences analysis by Mattias Neyt, Frank Hulstaert, Wilfried Gyselaers

“…The objective is to estimate the consequences of introducing NIPT for the detection of T21.Methods A cost-consequences analysis was performed presenting the impact on benefits, harms and costs. Context-specific real-world information was available to set up a model reflecting the current screening situation in Belgium. …”
Get full text

Inclusive green growth effects of China’s artificial intelligence development by HAN Xianfeng, LI Jiajia, ZHU Chengliang

“…Specifically, as AI levels increased, its impact on urban inclusive green growth first increased and then decreased. The current AI development level (0.003) was substantially below the theoretical optimal threshold (0.441). …”
Get full text

Interleukin-35 impairs human NK cell effector functions and induces their ILC1-like conversion with tissue residency features by Valentin Picant, Lara Revol-Bauz, Laurie Tonon, Timothée Casini, Aurélien Voissière, Dominique Poujol, Emilie Picard, Céline Rodriguez, Cyril Degletagne, Emily Sible, Uzma Hasan, Anthony Ferrari, Christophe Caux, Nathalie Bendriss-Vermare

“…Abstract Natural Killer (NK) cells play pivotal immunological roles including direct cytotoxic effector function and secretion of inflammatory and immunomodulating cytokines. In the context of chronic inflammation, NK cell fitness decreases during disease progression through currently unknown mechanisms. …”
Get full text

Optimizing the acid resistance of concrete with granulated blast-furnace slag by Luca-Alexander Kempf, Rolf Breitenbücher, Christian Gerten, Andreas Ehrenberg

“…The results serve as a basis for the development of highly acid-resistant concretes using blast-furnace slag-containing binder systems. Currently, the acid resistance of those concretes is being investigated in a long-term study by outsourcing representative test specimens into the Emscher sewer.…”
Get full text

Antimicrobial resistance: Past, present, and way forward by Ramashankar Rath, Pradip Kharya, Aroop Mohanty, Anil R. Koparkar, Anand M. Dixit, Hari Shanker Joshi, Vivek Hada

“…A containment plan is currently being executed but yet to achieve the full extent as intended. …”
Get full text

Microscopically controlled surgery with three-dimensional histology, tumescent local anesthesia and intracutaneous sutures for high tension in the treatment of skin cancer by H. Breuninger, I. A. Belova

“…Automated subcutaneous tumescent local anesthesia (ATLA). Since ATLA contains a highly diluted (up to 100 times) anesthetic, we can inject a 100-fold larger volume, thus, increasing the anesthetized area. …”
Get full text

Teaching English Oral Expressionand Listening Comprehension at the Department ofLetters and English Language, University of Constantine 1: Past and Present Ups and Downs by Youcef BEGHOUL

“…It also suggests some solutions for a more practical teaching of these two crucial skills in a pedagogical context characterized by ever decreasing linguistic and cultural levels and more and more overcrowded classes.…”
Get full text

Microvesicles Derived from Human Embryonic Neural Stem Cells Inhibit the Apoptosis of HL-1 Cardiomyocytes by Promoting Autophagy and Regulating AKT and mTOR via Transporting HSP-70 by Lei Zhang, Jianyi Gao, Tianyan Chen, Xiang Chen, Xianyan Ji, Kai Ye, Jiahong Yu, Bin Tang, Yusheng Wei, Hong Xu, Jiabo Hu

“…Additionally, hESC-NSC-derived MVs contained high levels of heat shock protein 70 (HSP-70), which can increase the level of HSP-70 in cells. …”
Get full text

In vitro antitumor and immunomodulatory activities of 1,2,4-oxadiazole derivatives by Héverton Mendes Araújo, Gabriel Acácio de Moura, Yasmim Mendes Rocha, Cristian Vicson Pinheiro Gomes, Valentina Nascimento e Melo de Oliveira, Ronaldo Nascimento de Oliveira, Larissa Deadame de Figueiredo Nicolete, Emanuel Paula Magalhães, Ramon R.P.P.B. de Menezes, Roberto Nicolete

“…Exposure to melanoma murine supernatants also promotes M1 polarization. Supernatants containing traces of 1,2,4-oxadiazole derivative 2 (Supernatants B, C, and D) increased the percentage of M1 cells compared to Supernatant A, as well as elevated levels of nitrite, TNF-α, and IL-12. 1,2,4-oxadiazole derivative 2 combined with Supernatant A and 1,2,4-oxadiazole derivative 2 combined with LPS also resulted in higher M1 polarization, suggesting a synergistic effect on M1 polarization and TNF-α production. …”
Get full text

Spaciotemporal distribution characteristics of glacial lakes and the factors influencing the Southeast Tibetan Plateau from 1993 to 2023 by Yu Mingwei, Guo Yonggang, Zhang Jian, Li Feng, Su Libin, Qin Deshun

“…However, given the backdrop of a slight increase in precipitation and a gradual increase in temperature, the proliferation of glacial lakes is projected to accelerate predominantly in Nyingchi City’s eastern and western regions.…”
Get full text

Safety of a change of specifications of phytosterols/phytostanols as a novel food pursuant to Regulation (EU) 2015/2283 by EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA), Dominique Turck, Torsten Bohn, Montaña Cámara, Jacqueline Castenmiller, Stefaan De Henauw, Karen Ildico Hirsch‐Ernst, Ángeles Jos, Alexandre Maciuk, Inge Mangelsdorf, Breige McNulty, Androniki Naska, Kristina Pentieva, Alfonso Siani, Frank Thies, Margarita Aguilera‐Gómez, Francesco Cubadda, Thomas Frenzel, Marina Heinonen, Monika Neuhäuser‐Berthold, Helle Katrine Knutsen, Morten Poulsen, Miguel Prieto Maradona, Josef Rudolf Schlatter, Alexandros Siskos, Henk vanLoveren, Wolfgang Gelbmann, Harry J. McArdle

“…Regarding the maximum limit of the specification parameter ‘other sterols/stanols’, the applicant asks for an increase from currently less than 3% to less than 7% to better reflect and cover the natural composition and proportions of sunflower‐based phytosterols/phytostanols, noting that the existing specifications have been established largely based on the NF when sourced from soy. …”
Get full text

Optimizing enzyme thermostability by combining multiple mutations using protein language model by Jiahao Bian, Pan Tan, Ting Nie, Liang Hong, Guang‐Yu Yang

“…It showed a 10.19°C increase in the melting temperature and an ~655‐fold increase in the half‐life at 58°C. …”
Get full text

Investigating The Performance Of Local And Indigenous Businesses In Times Of Economic Recession With Emphasis On Developing The Capabilities Of Cooperatives In Sistan And Baluchest... by Ali Asghar Tabavar, Abdoulnaser Derakhshan, Sahar Arefi

“…A more general definition of economic recession is a significant decrease in activity in the entire economy that lasts at least a few months. …”
Get full text