Multi-omics reveals total flavones from Abelmoschus manihot (L.) Medik. [Malvaceae] ameliorate MAFLD via PI3K/AKT/mTOR-mediated autophagy by Chao Lv, Chao Lv, Chao Lv, Chao Lv, Chao Lv, Lei Zhao, Jiani Hou, Hongyin Sun, Hongyin Sun, Hongyin Sun, Zhongsha Li, Zhongsha Li, Zhongsha Li, Zhongsha Li, Yuesong Wu, Yuesong Wu, Yuesong Wu, Yuesong Wu, Peizheng Shi, Yaping Xiao, Yunjin Xie, Yunjin Xie, Yunjin Xie, Yunjin Xie, Wei Su, Wei Su, Wei Su, Wei Su, Mingzhu Yin, Mingzhu Yin, Mingzhu Yin, Mingzhu Yin

“…(Malvaceae), abbreviated as TFA, in the context of MAFLD. Ultra-high-performance liquid chromatography-quadrupole orbitrap mass spectrometry (UHPLC-QTOF-MS) was used to identify the metabolites in TFA. …”
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Selective Dissolution of Clay Minerals in Tight Sandstone by Organic Acids by Fei YANG, Zhichao SHEN, Jiangmin DU, Fang WANG, Bo DONG

“…BACKGROUNDImproving the prediction ability of relatively high-quality reservoirs under tight backgrounds is a bottleneck and a challenge in current oil and gas exploration and development theories. …”
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Insights from UKCTOCS for design, conduct and analyses of large randomised controlled trials by Usha Menon, Aleksandra Gentry-Maharaj, Matthew Burnell, Sophia Apostolidou, Andy Ryan, Jatinderpal K Kalsi, Naveena Singh, Lesley Fallowfield, Alistair J McGuire, Stuart Campbell, Steven J Skates, Anne Dawnay, Mahesh Parmar, Ian J Jacobs

“…Future work There is a pressing need to increase the evidence base to support decision making about all aspects of trial methodology. …”
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Growth Toxic Effects of Metal Nanoparticles on Bacillus subtilis and Vibrio parahaemolyticus by Shiyu CHEN, Bin XIA, Lin ZHU, Shuang LI, Qiufen LI, Xuemei SUN, Wei DAI

“…The obtained response values are proportional to the concentration and mobility of the ionic current in culture mediums. Since the uncharged or weakly charged substrate will be converted into highly charged small-molecule substances during the growth and proliferation of bacteria—thus increasing the culture medium conductivity—the bacterial growth process can be recorded quickly and accurately by detecting the change in the conductivity of the culture medium. …”
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A group psychological intervention for postnatal depression in British mothers of South Asian origin – the ROSHNI-2 RCT by Nusrat Husain, Karina Lovell, Carolyn A Chew-Graham, Farah Lunat, Penny Bee, Matthias Pierce, Najia Atif, Saadia Aseem, Kamaldeep Bhui, Peter Bower, Traolach Brugha, Nasim Chaudhry, Akbar Ullah, Linda Davies, Nadeem Gire, Deepali Sharma, Jahanara Miah, Waqas Ahmed, Joe Kai, Ilyas Mirza, Jillian Morrison, Naeem Mohmed, Atif Rahman, Shanaya Rathod, Najma Siddiqi, Waquas Waheed, Christopher Williams, Nosheen Zaidi, Richard Emsley, Richard Morriss

“…The perceived benefit of increased social relationships during the PHP sessions could have provided an influential therapeutic factor. …”
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Human immunodeficiency virus prevention and testing strategies among men who have sex with men in the UK: the PANTHEON research programme including the SELPHI RCT by Janey Sewell, T Charles Witzel, David Dunn, Fiona Lampe, Fiona Burns, Peter Weatherburn, Sheena McCormack, Leanne McCabe, Alec Miners, Valentina Cambiano, Roger Pebody, Roy Trevelion, Nadia Hanum, Andrew Phillips, Alison Rodger

“…Modelling suggested that provision of oral tenofovir/emtricitabine pre-exposure prophylaxis increased human immunodeficiency virus testing, with anti-retroviral therapy initiation at diagnosis, and reductions in the level of condom-less sex, that each played an important role in decreasing human immunodeficiency virus incidence among men who have sex with men, and that the current human immunodeficiency virus incidence would have been double what it is if any one of them had not occurred. …”
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Mineralogy and sulfide mineral chemistry of Khabr iron ore, Southwest of Baft (Southeast of Sanandaj-Sirjan Zone) by Mohammad Boomeri, Habib Biabangard, Somayeh Dehghani Soltani, Azadeh Bordbar

“…Discussion and Results  The iron mineralization occurs at the contact of carbonate rocks and phyllite and schists. …”
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The study of Effective and Efficient Organizational Change Processes with an Emphasis on Islamic Management by Fazel Hajizadeh Ebrahimi, Hamid Moakedi

“…AbstractToday, effective and efficient change management has attracted the attention of managers in various organizations and companies from the highest management level to the last levels. In performing the current business, all managers should take into account the fact that making appropriate and effective changes has become one of the fixed features in the administrative system of the society. …”
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Comparative Ethics of Modern Payment Models by Jacob Riegler

“…This article examines the alignment of current predominant payment models of fee-for-service, capitation, and value-based payments with patient care ethics. …”
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Comparative Ethics of Modern Payment Models by Jacob Riegler

“…This article examines the alignment of current predominant payment models of fee-for-service, capitation, and value-based payments with patient care ethics. …”
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Multi-source Data-driven Analysis of Deformation and Influencing Factors for Expansive Soil Canal Slopes by ZHANG Yuhan, HU Jiang, LI Xing

“…Moreover, dense deployment of monitoring points not only increases construction challenges but also significantly raises project costs. …”
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Emotional literacy programme in special schools for children with a learning disability in England: the ZF-SEND feasibility RCT by Biza Stenfert Kroese, Gemma Unwin, Richard Hastings, Andrew Jahoda, Rachel McNamara, David Gillespie, Jeremy Segrott, Kate Ingarfield, Myrsini Gianatsi, Elizabeth Randell, Zoe Mather, Barbara Barrett, Poushali Ganguli, John Rose, Mariam Sahle, Emily Warren, Nathan Da Cruz

“…Future work On the basis of the current findings, an application for a full trial will be prepared and submitted with a number of amendments. …”
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Integrating Palliative Care and Heart Failure: the PalliatHeartSynthesis realist synthesis by Tracey McConnell, Carolyn Blair, Geoff Wong, Claire Duddy, Clare Howie, Loreena Hill, Joanne Reid

“…CMOc 3 identified the importance of increased awareness and seeing benefits of PC in HF management (CMOc 3) as key intervention strategies. …”
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Museums and Geoconservation by Michael J. Benton, Sarah King

“…He also sees real impacts from increasing awareness among professionals and the public for issues associated with decolonization issues and the climate crisis. …”
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Rapid tests to inform triage and antibiotic prescribing decisions for adults presenting with suspected acute respiratory infection: a rapid evidence synthesis of clinical effective... by Katie Scandrett, Jill Colquitt, Rachel Court, Fiona Whiter, Bethany Shinkins, Yemisi Takwoingi, Emma Loveman, Daniel Todkill, Paramjit Gill, Daniel Lasserson, Lena Al-Khudairy, Amy Grove, Yen-Fu Chen

“…Rapid tests that can be done and produce results quickly (within 45 minutes) are now available. It is currently unclear whether the use of these rapid tests to assess patients would improve or worsen patient outcomes or increase or decrease costs overall. …”
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Digital augmentation of aftercare for patients with anorexia nervosa: the TRIANGLE RCT and economic evaluation by Janet Treasure, Katie Rowlands, Valentina Cardi, Suman Ambwani, David McDaid, Jodie Lord, Danielle Clark Bryan, Pamela Macdonald, Eva Bonin, Ulrike Schmidt, Jon Arcelus, Amy Harrison, Sabine Landau

“…The majority (76%) were recruited from inpatient care, including 19% currently admitted under the Mental Health Act (MHA) [16% had previous admissions (median 2) under the MHA]. …”
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Urodynamics tests for the diagnosis and management of male bladder outlet obstruction: long-term follow-up of the UPSTREAM non-inferiority RCT by Madeleine Clout, Amanda L Lewis, Madeleine Cochrane, Grace J Young, Paul Abrams, Peter S Blair, Christopher Chapple, Gordon T Taylor, Sian Noble, Tom Steuart-Feilding, Jodi Taylor, J Athene Lane, Marcus J Drake

“…Men were excluded if they were unable to pass urine without a catheter, had a relevant neurological disease, were currently undergoing treatment for prostate or bladder cancer, had previous prostate surgery or were unfit for surgery. …”
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Urodynamics tests for the diagnosis and management of male bladder outlet obstruction: long-term follow-up of the UPSTREAM non-inferiority RCT by Madeleine Clout, Amanda L Lewis, Madeleine Cochrane, Grace J Young, Paul Abrams, Peter S Blair, Christopher Chapple, Gordon T Taylor, Sian Noble, Tom Steuart-Feilding, Jodi Taylor, J Athene Lane, Marcus J Drake

“…Men were excluded if they were unable to pass urine without a catheter, had a relevant neurological disease, were currently undergoing treatment for prostate or bladder cancer, had previous prostate surgery or were unfit for surgery. …”
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Impact of frailty in older people on health care demand: simulation modelling of population dynamics to inform service planning by Bronagh Walsh, Carole Fogg, Tracey England, Sally Brailsford, Paul Roderick, Scott Harris, Simon Fraser, Andrew Clegg, Simon de Lusignan, Shihua Zhu, Francesca Lambert, Abigail Barkham, Harnish Patel, Vivienne Windle

“…Mean face-to-face appointments were generally similar within frailty categories across age groups, but with a notable decrease in appointments with older age in the severe category. …”
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Supporting antiretroviral therapy uptake and adherence: the SUPA research programme and RCT by Rob Horne, Caroline Sabin, Trudie Chalder, Vanessa Cooper, Lucy Campbell, Elizabeth Glendinning, Iris Mosweu, Paul McCrone

“…We interviewed 52 men and women from Black African and Caribbean communities in London who had been identified as having previous or current problems adhering to their medication. Two separate analyses were conducted. …”
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