What happens between first symptoms and first acute exacerbation of COPD – observational study of routine data and patient survey by Alex Bottle, Alex Adamson, Xiubin Zhang, Benedict Hayhoe, Jennifer K Quint

“…Most patients were offered the flu jab. Older patients, current smokers and those with other conditions such as heart failure had higher risk of an acute exacerbation. …”
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Mapping evidence of spinal manipulation therapy for headaches in South Africa: a scoping review of grey literature by Keseri Padayachy, Ismail Fatima, Morris Kahere, Alister du Rose, Katherine A. Pohlman

“…Abstract Objective Spinal manipulative therapy (SMT) has been demonstrated to be an effective management approach for primary headaches; however, current literature often excludes data from South Africa (SA). …”
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Cost-utility of aripiprazole once-monthly versus paliperidone palmitate once-monthly injectable for schizophrenia in China. by Yiping An, Gang Fang, Zhipeng Pi, Yumeng Zhang, Wei Li, Jinxi Ding

“…A cost-effectiveness threshold (CET) of 0.51 times China's 2023 gross domestic product (GDP) (US$ 6,394.536) was used to judge the economics of intervention.<h4>Results</h4>The current price of AOM in China is relatively high (US$418.140). …”
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“They tossed me up like a ball”: informal settlement residents’ experiences in accessing healthcare in Kampala, Uganda by Julia Dickson-Gomez, Kirsten Beyer, Arthur Kiconco, Ronald Anguzu, Agnes Nyabigambo

“…The focus group interviews indicated that private healthcare systems have created incentives to draw resources away from already depleted public healthcare systems, further decreasing access to the most vulnerable. Conclusions Our study reveals important and substantial gaps in the current healthcare system in Uganda. …”
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Comparison of Bone Mineral Density in Lumbar Spine and Fracture Rate among Eight Drugs in Treatments of Osteoporosis in Men: A Network Meta-Analysis. by Ling-Xiao Chen, Zhi-Rui Zhou, Yu-Lin Li, Guang-Zhi Ning, Tian-Song Zhang, Di Zhang, Shi-Qing Feng

“…<h4>Context</h4>The preferred treatment for osteoporosis in men is debated, and pairwise meta-analysis cannot obtain hierarchies of these treatments.…”
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Analysis of Adaptation of Students Studying under the Flipped Classroom Model to the Conditions of Distance Learning by G. R. Chaynikova

“…At the same time, it is necessary to keep in mind the importance of pedagogical support in the context of e-learning.…”
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Insulin Modulates NK Cell Activity in Liver Fibrosis MASH Patients via the STING Pathway by Johnny Amer, Ahmad Salhab, Amiram Ariel, Rifaat Safadi

“…While STING is well-established in various immune cells, its role in natural killer (NK) cells, particularly within the context of liver fibrosis, remains inadequately explored. …”
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Establishing priorities for future land conservation to maximise biodiversity conservation and other ecosystem services in the Tilarán Mountains of Costa Rica by Lindsay Stallcup, Matthew D. Moran, Doris Rojas, Erich Mata

“…The opportunity to connect currently protected areas to one another through effective biological corridors still remains, possibly through conservation partnerships with landowners or direct land purchase, but time could be short as increasing development and changing land-use patterns threaten to further isolate habitats in the MAB.…”
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The Landing Error Scoring System (LESS) and Lower Limb Power Profiles in Elite Rugby Union Players by Stephen Rowell, Nicola Relph

“…Participants scoring moderate to poor in the LESS recorded significantly higher power and reactive strength index, increased contact time but not jump height. This suggests participants with high-risk landing biomechanics may also produce higher performance measures, but these do not necessarily result in an improved jump height.…”
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Incubation of semen with human follicular fluid improves the antioxidant status and quality of spermatozoa after freezing–thawing by Monireh Mahmoodi, Elham Shojafar, Maryam Dastjani-Farahani

“…Therefore, most studies are currently focused on optimizing this method to achieve high-quality semen after thawing. …”
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Preparation and Characterization of Activated Carbon Made from Robusta Coffee Skin (Coffea Canephora) by Raudhatul Raihan, Adi Setiawan, Lukman Hakim, Muhammad Muhammad, Muhammad Arif, Hadi Hosseiniamoli

“…Indonesia is one of the coffee-producing countries where production tends to increase from year to year. Currently, residuals from coffee-fruit processing such as coffee-skin and husks are thrown away without any use and this biomass residual contains several toxic chemicals such as alkaloids, tannins, and polyphenols. …”
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Per- and Polyfluoroalkyl Substances (PFAS) in Consumer Products: An Overview of the Occurrence, Migration, and Exposure Assessment by Yang Yang, Jin Wang, Shali Tang, Jia Qiu, Yan Luo, Chun Yang, Xiaojing Lai, Qian Wang, Hui Cao

“…The types of consumer products considered here include food contact materials, textiles, and disposable personal hygiene products. …”
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Comprehensive analysis of kampo medicine utilization across all outpatient departments with a focus on anesthesiology department/pain clinic at Kyoto university hospital over 12 ye... by Karin Kato, Kaori Tsuyuki, Takuma Ohsuga, Akihiko Ueda, Miho Egawa, Masashi Ikuno, Neiko Ozasa, Kiyoaki Tanikawa

“…The usage rate of Processed Aconite Root-containing formulations increased with increasing patient age, reaching 3.3% in individuals in their teens, 6.6% in their twenties, 13.3% in their thirties, and over 30% in their eighties and nineties. …”
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Landslide activation during deglaciation in a fjord-dominated landscape: observations from southern Alaska (1984–2022) by J. Walden, J. Walden, M. Jacquemart, M. Jacquemart, B. Higman, R. Hugonnet, R. Hugonnet, R. Hugonnet, A. Manconi, A. Manconi, D. Farinotti, D. Farinotti

“…Additionally, many glaciers in this area are retreating out of glacially carved fjords, leaving landslides in contact with deep waterbodies that can substantially increase the reach of a catastrophic failure through displacement waves or hazard cascades. …”
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Screening of Positive Regulatory Stimuli for Stomatal Opening in Chinese Cabbage by Jin-Yan Zhou, Dong-Li Hao, Ze-Chen Gu

“…Increasing the stomatal aperture is a crucial strategy for enhancing the rate of CO₂ absorption, which ultimately contributes to increased plant yield through improved photosynthetic activity. …”
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“Investigating the Synergistic Effects of Curcumin on the Oxidative Stability of Flaxseed (Linum usitatissimum) Oil: A Kinetic Study” by Mahya Azari, Mahsan Karimi, Seyed Mohammad Mazloomi, Mohammad-Taghi Golmakani, Azam Abbasi

“…In the current study, the change in entropy (ΔS) decreases to 1000 ppm curcumin which explains the slower rate of oxidation in this case. …”
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Quinine Use and the Risk of Exacerbations of Chronic Obstructive Pulmonary Disease: A Nationwide Retrospective Registry Study by Vilstrup F, Sivapalan P, Eklöf J, Jordan A, Biering-Sørensen T, Sperling S, Jensen JUS

“…An unadjusted analysis on the unmatched population showed similar results (HR 1.475, 95% CI 1.39 to 1.56).Conclusion: In the current study, we found an association between the use of Quinine in patients with COPD and an increased risk of acute exacerbations and death. …”
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Design and experiment of a Long Range Autonomous Underwater Vehicle for Ocean Acoustic Data Observation by Sun Qindong, Xu Shangfeng, Sun Tongshuai, Lu Faliang, Dong Pengfei, Chang Jiaqi

“…In order to realise noise measurement and target detection, this paper designs a long range autonomous underwater vehicle (LRAUV), namely ‘Petrel’, which contains a variable buoyancy system, attitude adjustment mechanisms, pitch and heading control planes, acoustic vector sensor (AVS) and a propeller. …”
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Replacing fishmeal with an insect meal blend: Implications for intestinal microbiota in European seabass by Violeta Kalemi, Simona Rimoldi, Rafaela S. Costa, Ana Basto, Marta Monteiro, Genciana Terova, Luisa M.P. Valente

“…This research stands out by examining a combination of IMs rather than a single source, thereby addressing an underexplored area in the current literature. In a feeding trial that lasted 75 days, European seabass were fed three different diets: a commercial-like control diet and two experimental diets containing partial replacement of FM with IM (25 % and 50 %). …”
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Tokenization and deep learning architectures in genomics: A comprehensive review by Conrad Testagrose, Christina Boucher

“…Current deep learning architectures and tokenization techniques have been explored for the extraction of meaningful underlying information contained within this sequencing data. …”
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