Granulocyte-Macrophage Colony-Stimulating Factor Inhibition Ameliorates Innate Immune Cell Activation, Inflammation, and Salt-Sensitive Hypertension by Hannah L. Smith, Bethany L. Goodlett, Gabriella C. Peterson, Emily N. Zamora, Ava R. Gostomski, Brett M. Mitchell

“…However, the role of granulocyte-macrophage colony-stimulating factor (GM-CSF) has not yet been explored in the context of SSHTN. Previously, we reported that GM-CSF is critical in priming bone marrow-derived (BMD)-macrophages (BMD-Macs) and BMD-dendritic cells (BMD-DCs) to become activated (CD38+) in response to salt. …”
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An Agent-Based Simulation and Optimization Approach for Sustainable Urban Logistics: A Case Study in Lisbon by Renan Paula Ramos Moreno, Rui Borges Lopes, Ana Luísa Ramos, José Vasconcelos Ferreira, Diogo Correia, Igor Eduardo Santos de Melo

“…This study examines the PDP-TW in an urban logistics context using an integrated approach that combines an agent-based simulation model and an optimization model. …”
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Two decades of cropland monitoring in Changsha-Zhuzhou-Xiangtan city group: trends and future predictions by Wenbo Zhang, Dazhao Fan, Song Ji, Yang Dong, Dongzi Li, Ming Li

“…The results demonstrated that the cropland area in the CZTCG in the past 20 years has shown a two-stage trend of increasing (2000–2015, increase of 8.25%) and decreasing (2015–2020, decrease of 2.91%), and the main reasons for cropland loss in the whole process of change were forest and building, with serious loss of cropland area in Changsha County and Wangcheng District. …”
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Is litter biomass a driver of soil volatile organic compound fluxes in Mediterranean forest? by M. Rocco, M. Rocco, J. Kammer, M. Santonja, B. Temime-Roussel, C. Saignol, C. Lecareux, E. Quivet, H. Wortham, E. Ormeño

“…We investigated in situ daily BVOC fluxes from bare soil and different litter biomasses mimicking current, lower, or higher litter production as both decreases and increases in litter accumulation are expected in the Mediterranean region under the current context of climate change and greening management policies. …”
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Comparison of Bone Mineral Density in Lumbar Spine and Fracture Rate among Eight Drugs in Treatments of Osteoporosis in Men: A Network Meta-Analysis. by Ling-Xiao Chen, Zhi-Rui Zhou, Yu-Lin Li, Guang-Zhi Ning, Tian-Song Zhang, Di Zhang, Shi-Qing Feng

“…Zoledronate ranked first for increasing the BMD in LS, and teriparatide (20mg) was ranked first for decreasing the fracture rate.…”
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Adolescent and parental proxy online record access: analysis of the empirical evidence based on four bioethical principles by Josefin Hagström, Maria Hägglund, Charlotte Blease

“…Methods In this paper, we apply biomedical ethical principles to explore key questions about adolescents’ and parents’ access to adolescents’ EHRs, with the aim of informing future discussions about the development of ethical and policy practice guidelines. Results Drawing on current empirical research, we find preliminary evidence that in some contexts, patient online record access (ORA) could help to facilitate autonomy for adolescents and parents as well as offering support in managing appointments and medications. …”
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Thermal and radiative effects on unsteady MHD flow of Casson fluid past a rotating porous medium with variable mass diffusion by J. Prakash, A. Selvaraj, P. Ragupathi, Qasem M. Al-Mdallal, S. Saranya

“…The findings indicate that buoyancy forces imparted by the Grashof numbers considerably increase the velocity due to convection currents. However, the magnetic parameter counteracts velocity due to the Lorentz force while larger porosity increases fluid flow. …”
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Quality failures in Energy- saving renovation projects in Northern China by Yuting Qi

“…However, in China, building energy renovation projects are subjected to quality failures resulting in energy wastage, a decrease in the energy efficiency of the project, an increase in project cost, and thus negatively affecting the overall performance of the renovation projects. …”
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Winter wheat yield responses to growing degree days: Long-term trends and adaptability in major producing areas of China by Ziyang Liu, Davide Cammarano, Xiaojun Liu, Yongchao Tian, Yan Zhu, Weixing Cao, Qiang Cao

“…The number of days in the growth period during the sowing-to-jointing stage and jointing-to-flowering stage decreased significantly, the number of days during the flowering-to-maturity stage increased significantly. …”
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Chemical characterization and cytotoxic effect of three edible fungi (Morchella) against breast cancer cells: A therapeutic approach

“…Current breast cancer therapeutics are associated with short-term efficacy, increased drug resistance, and severe adverse reactions, thus demanding the development of new therapeutic approaches. …”
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Insomnia, Cognitive Impairment, or a Combination of Both, Alter Lipid Metabolism Due to Changes in Acylcarnitine Concentration in Older Persons by Selma Karime Castillo-Vazquez, Berenice Palacios-González, Marcela Vela-Amieva, Isabel Ibarra-González, Ricardo Morales, Paola García-delaTorre, Sergio Sánchez-García, Carmen García-Peña, Ricardo Reyes-Chilpa, Raúl Hernán Medina-Campos, Jessica Hernández-Pineda, Juan Carlos Gomez-Verjan, Nadia Alejandra Rivero-Segura

“…Results: Our results show that insomnia increases the concentration of acylcarnitines (C10, C8, C14, C12:1, C18:1 and C18) as compared to CI group, while older persons with CI show a decrease the concentration of the acylcarnitines C16, C10 and C8. …”
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Strategies for adaptation of Russian commercial banks to innovative technologies by O. S. Solenaya

“…All banking innovations have a significant impact on the current business models of commercial banks, increasing the efficiency of their activities and at the same time the level of competition both in the banking sector and in the financial markets as a whole…”
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Cost-effectiveness of atezolizumab plus bevacizumab versus sorafenib as first-line therapy in unresectable hepatocellular carcinoma in the US and Chinese setting: a modelling compa... by Lei Wang, Lulu Liu, Yiling Ding, Qilin Zhang, Yamin Shu

“…In scenario analyses, the atezolizumab plus bevacizumab treatment becomes favourable when the cost of atezolizumab decreases to 67.85% and 18.45% of its original price in the USA and China, respectively.Conclusions The atezolizumab plus bevacizumab is unlikely to be cost-effective compared with sorafenib for patients with unresectable HCC in the context of the USA and China. …”
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Application of urinary peptide-biomarkers in trauma patients as a predictive tool for prognostic assessment, treatment and intervention timing by Gökmen Aktas, Felix Keller, Justyna Siwy, Agnieszka Latosinska, Harald Mischak, Jorge Mayor, Jan Clausen, Michaela Wilhelmi, Vesta Brauckmann, Stephan Sehmisch, Tarek Omar Pacha

“…CE-MS peptidome analysis identified 191 significantly altered peptides in severely injured patients. A consistent increase in the abundance of peptides from A1AT, AHSG, and HBA1 was observed, while peptides derived from PIGR and UROM were consistently decreased. …”
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Motivation to learn German as a foreign language: A systematic literature review by Asuman Yaprak

“…The findings show that motivation studies on German as a foreign language are primarily based on the second language motivational self-system model, the number of studies has increased with the paradigm shift, quantitative research methods and surveys are mainly used as data collection techniques, German is intensively researched together with other languages, and the aim is to determine what increases and decreases motivation by considering motivation levels and factors more.…”
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Bleomycin: A worthy alternative by Gursev Sandlas, Paras Kothari, Parag Karkera, Abhaya Gupta

“…Complications of the therapy were few and far between. 2 patients developed fever after injection, one patients reported a transient increase in size of swelling, 2 patients have developed discoloration of the overlying skin and are currently being followed up for final outcome. …”
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Shifting of Distribution and Changing of Antibiotic Resistance in Gram-Positive Bacteria from Bile of Patients with Acute Cholangitis by Hao Y, Li L, Du W, Lu J

“…Yuqi Hao,1 Lianxin Li,2 Wenting Du,1 Jinshuai Lu1 1Department of General Internal Medicine, People’s Hospital of Xinjiang Uygur Autonomous Region, Urumqi, Xinjiang, People’s Republic of China; 2Endoscopy Center, People’s Hospital of Xinjiang Uygur Autonomous Region, Urumqi, Xinjiang, People’s Republic of ChinaCorrespondence: Jinshuai Lu, Department of General Internal Medicine, People’s Hospital of Xinjiang Uygur Autonomous Region, Urumqi, Xinjiang, People’s Republic of China, Email lujinshuai@xjrmyy.comBackground: Gram-negative bacteria are the predominant pathogens responsible for biliary infections; however, the prevalence of Gram-positive bacteria is currently increasing. Investigating the bacterial spectrum and evolving antibiotic resistance patterns of Gram-positive bacteria is crucial for optimizing the management of acute cholangitis, particularly in the context of the global rise in antibiotic resistance.Methods: This retrospective analysis focused on Gram-positive bacteria isolated from the bile of patients undergoing biliary drainage with acute cholangitis at our hospital from January 1, 2018, to March 31, 2024. …”
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Quinoa in Peru: Andean Pseudocereal, a food for present and future generations by Jesús De La Cruz-Arango

“…This is especially important in the current context, and it is necessary to take measures to adapt to climate change7. …”
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Multidisciplinary approach to the diagnosis of disorders of coagulation system in childrenwith various pathologies by O. B. Gordeeva, M. S. Karaseva, D. E. Lavretsky, M. A. Babaikina, N. D. Vashakmadze, M. A. Soloshenko, G. V. Revunenkov, E. A. Abashidze, M. V. Egorova

“…Thrombosis in children with genetically determined thrombophilia often occur in the context of risk factors. In the early neonatal period, the deficiency of anticoagulant factors manifests as the form of fulminant purpura, followed by the development of skin necrosis. …”
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A Sociological study of the Relationship between Smartphone Addiction and Phubbing Case Study18-29 Year Old Females of Ramhormoz City by Ali Boudaghi, Ali Hossein Hosseinzadeh, Sayedeh Sara Mousavi Moghadam

“…In recent years, along with the digital transition and the increase of smart phone users, phubbing, as an emerging phenomenon, has drawn the attention of scholars and experts. …”
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