How do patients, medical assistants and physicians accept and experience tablet-based cognitive testing by medical assistants in general practice? - A qualitative study by Kristin Rolke, Carolin Rosendahl, Klaus Weckbecker, Alexander Hanke, Michael Wagner, Leon Nissen, Lara Marie Reimer, Stephan Jonas, Philipp Schaper, Jochen René Thyrian, Florian Schweizer, Judith Tillmann

“…Abstract Background Approximately 1.8 million people with dementia live in Germany and the number is expected to increase in the coming years. Between 360,000 and 440,000 new cases are diagnosed each year. …”
Get full text

In vivo Confocal Microscopy for Corneal and Ocular Surface Pathologies: A Comprehensive Review by Ramirez-Miranda A, Guerrero-Becerril J, Ramirez M, Vera-Duarte GR, Mangwani-Mordani S, Ortiz-Morales G, Navas A, Graue-Hernandez EO, Alio JL

“…Advances in imaging technologies and the integration of artificial intelligence hold the potential to overcome current limitations, enhancing its diagnostic precision and applicability. …”
Get full text

Economic burden of PTSD in the UK: a systematic review and economic analysis by Siddhartha Bandyopadhyay, Paul Montgomery-Marks, Clio Belle Weisman, Tamoghna Bose

“…The details of these costs in the UK are currently, we believe, unknown.Design Our methodology was developed collaboratively with a collaborative advisory group of clinicians, patients, carers and other stakeholders. …”
Get full text

Polyaniline/Ti₃C₂ MXene Composites with Artificial 3D Biomimetic Surface Structure of Natural Macaw Feather Applied for Anticorrosion Coatings by Chen-Cheng Chien, Yu-Hsuan Liu, Kun-Hao Luo, Ting-Yun Liu, Yi-Ting Kao, Shih-Harn Yang, Jui-Ming Yeh

“…SCE, reduces the corrosion current density (I_corr) from 1.09 µA/cm² to 0.035 µA/cm², and raises the impedance modulus at 0.01 Hz from 67 kΩ to 3794 kΩ. …”
Get full text

Efficacy and safety of compound glycyrrhizin combined with topical minoxidil for alopecia areata: a systematic review and meta-analysis of randomized controlled trials by Chenqi Guo, Xiangru Gu, Junchen Li, Yingdong Wang, Xiaoya Liu, Guojing Yang, Min Zhang, Yu Zhang

“…The SALT score (MD = −10.09, 95% CI [−12.89, −7.30], p < 0.00001), serum TNF-α levels (MD = −0.99, 95% CI [−1.19, −0.39], p < 0.00001), serum IL-12 levels (MD = −8.84, 95% CI [−11.20, −6.47], p < 0.00001) and serum IFN-γ levels (MD = −7.44, 95% CI [−11.51, −3.37], p = 0.0003) were reduced, and the serum TGF-β1 levels (MD = 2.40, 95% CI [1.24, 3.57], p < 0.0001) were increased. There were no significant differences in reported adverse events, including irritant contact dermatitis (RR = 0.51, 95% CI [0.25, 1.01], p = 0.05),’ gastrointestinal reactions (RR = 2.47, 95% CI [0.49, 12.55], p = 0.28), lower limb edema (RR = 2.60, 95% CI [0.61, 11.06], p = 0.20), facial edema (RR = 2.33, 95% CI [0.61, 8.93], p = 0.22), or localized itching (RR = 0.56, 95% CI [0.18, 1.75], p = 0.32), between the two groups.Conclusion The current evidence indicates that CG combined with topical minoxidil therapy is effective and safe for AA. …”
Get full text

Thermal Rejection Assessment: New Strategies for Early Detection by Irina Filz von Reiterdank, Irina Filz von Reiterdank, Irina Filz von Reiterdank, Irina Filz von Reiterdank, Rohil Jain, Rohil Jain, Eloi de Clermont-Tonnerre, Eloi de Clermont-Tonnerre, Eloi de Clermont-Tonnerre, Eloi de Clermont-Tonnerre, Alexandra Tchir, Alexandra Tchir, Curtis L. Cetrulo, Curtis L. Cetrulo, Alexandre G. Lellouch, Alexandre G. Lellouch, J. Henk Coert, Aebele B. Mink van der Molen, Shannon N. Tessier, Shannon N. Tessier, Korkut Uygun, Korkut Uygun

“…This approach may reduce the need for invasive biopsies, thereby improving patient comfort and reducing potential complications associated with current diagnostic methods.…”
Get full text

Epidemiological Situation on Cholera in the Russian Federation in 2023 and Forecast for 2024 by A. Yu. Popova, A. K. Noskov, E. B. Ezhlova, V. D. Kruglikov, E. V. Monakhova, O. S. Chemisova, A. A. Lopatin, S. M. Ivanova, O. A. Podoynitsyna, A. S. Vodop’yanov, D. A. Levchenko, I. V. Savina

“…The risks of epidemic manifestations of cholera are especially high in the territories of the constituent entities of the Russian Federation which are under ongoing emergency, due to migration processes, and the impact of other risk-forming factors that contribute to an increase in the degree of contact of the population with water bodies contaminated with cholera vibrios. …”
Get full text

Monkeypox virus (MPXV) isolation from longitudinal samples of 11 patients to infer risk of onwards transmission by Dr Helen Callaby, Dr Janie Olver, Ms Kirsty Emery, Dr Kevin Richards, Dr Marian Killip, Dr Natalie Groves, Dr Jake Dunning, Professor Malcolm G Semple, Professor J Kenneth Baillie, Dr Tommy Rampling, Dr Catherine F Houlihan

“…Human-to-human transmission occurs, primarily through contact with infectious lesions. The cycle threshold (Ct) value at which mpox virus can be isolated varies in the literature. …”
Get full text

Рreventive efficacy of interferon -2b in the COVID-19 pandemic by Zh. B. Ponezheva, A. A. Grishaeva, I. V. Mannanova, A. N. Kupchenko, S. B. Yatsyshina, S. V. Krasnova, V. V. Malynovskaya, V. G. Akimkin

“…The amount of infected people has already exceeded 48 million, and more than 1 million deaths have been registered. A steady increase of new cases of COVID-19 is currently observed on the territory of the Russian Federation. …”
Get full text

Climate and human activities alter coupling of soil macro- and micronutrients: Evidence from a long-term experiment in typical steppes by Yi Zhou, Shenghua Chang, Xiaojuan Huang, Wenjun Wang, Fujiang Hou, Yanrong Wang, Zhibiao Nan

“…Our results showed decreases in soil Zn and Fe stocks, alongside increases in Cu, SOC, and STN stocks over time. …”
Get full text

Implementation of a digital nurse to improve the use of digital health applications (DiGA) for older people with depressive disorders (DiGA4Aged): a randomized proof of concept stu... by Anna Mai, Magdalena Pape, Theresa Sophie Busse, Katharina Kunde, Jennifer Bosompem, Chantal Giehl, Ina Carola Otte, Stephan Herpertz, Georg Juckel, Ida Haussleiter, Rainer Wirth, Horst Christian Vollmar, Nina Timmesfeld, Jan Dieris-Hirche

“…Discussion In Germany, the approved DiGA are currently little used, especially by people with a low digital affinity. …”
Get full text

A group psychological intervention for postnatal depression in British mothers of South Asian origin – the ROSHNI-2 RCT by Nusrat Husain, Karina Lovell, Carolyn A Chew-Graham, Farah Lunat, Penny Bee, Matthias Pierce, Najia Atif, Saadia Aseem, Kamaldeep Bhui, Peter Bower, Traolach Brugha, Nasim Chaudhry, Akbar Ullah, Linda Davies, Nadeem Gire, Deepali Sharma, Jahanara Miah, Waqas Ahmed, Joe Kai, Ilyas Mirza, Jillian Morrison, Naeem Mohmed, Atif Rahman, Shanaya Rathod, Najma Siddiqi, Waquas Waheed, Christopher Williams, Nosheen Zaidi, Richard Emsley, Richard Morriss

“…The perceived benefit of increased social relationships during the PHP sessions could have provided an influential therapeutic factor. …”
Get full text

High-risk pregnancy and risk of breastfeeding failure by Eman S. Salama, Mostafa Hussein, Ahmed N. Fetih, Azza M. A. Abul-Fadl, Shimaa A. Elghazally

“…A pretested and validated questionnaire was used to collect detailed epidemiological, personal, health-related status, medications, hospitalizations, reproductive history, current delivery, and previous breastfeeding experiences. …”
Get full text

Web-Based Respondent-Driven Sampling to Assess Biobehavioral Factors Among Men Who Have Sex With Men in Thailand: Cross-Sectional Study by Watcharapol Srinor, Suvimon Tanpradech, Panupit Thiengtham, Samart Karuchit, Charif Naksuk, Thitipong Yingyong, Thananda Naiwatanakul, Sanny Northbrook, Wolfgang Hladik

“… Abstract BackgroundRespondent-driven sampling (RDS) is the current standard for sampling key populations at risk for HIV infections but is usually limited to local implementation in single towns or cities. …”
Get full text

Use of ICT to Confront COVID-19 by Yousry Saber El Gamal

“…Supporting a digitized world and staying current in the latest technology will be essential for any country to remain competitive in a post COVID-19 world. …”
Get full text

Seismic Performance of Steel Column Base of Disc-spring Self-centering Energy-consuming Damper by SUN Jiateng, LIU Jianming, ZHU Guangzhi

“…When the number of shear energy dissipation plates is increased, the maximum stiffness, maximum residual deformation and energy consumption are increased by 20%, 25% and 20% respectively. …”
Get full text

NECROSIS AS A COMPLICATION OF LOCAL ANESTHESIA IN DENTISTRY by V.V. Lepsky, C. V. Osik

“…However, as a rule, most of the groups of painkillers contain vasoconstrictors of the cartridge, such as adrenaline hydrochloride, noradrenaline, although the last one is currently banned for use because of the complications that it can cause. …”
Get full text

Characterizing obesity: A qualitative study by Tim Bober, Flor Cameron, Lane Alexander, J.G. Luiggi-Hernandez, David Rometo, Linda-Marie Lavenburg, Haley Grant, Emily Klawson, Autumn R. Boyer, Kathleen M. McTigue, Julie Gouveia-Pisano, Avani Patel, Lisa Tarasenko, Jannette Escobar, Allison Brenner, Scott M. Vouri, Feng Dai, Megan E. Hamm

“…Conclusion: This qualitative study of people with obesity, health professionals, and payors demonstrated current views of addressing and treating obesity in clinical settings. …”
Get full text

Oral-Delivery Lactococcus lactis expressing cherry fusion lactoferrin peptides against infection of avian pathogenic Escherichia coli in chickens by Zhuoran Li, Xueying Wang, Dianzhong Zheng, Fuzhen Han, Yue Li, Han Zhou, Jiaxuan Li, Wen Cui, Yanping Jiang, Xiaona Wang, Weichun Xie, Lijie Tang

“…Historically, antibiotics and vaccinations currently control APEC infections in poultry, however, antibiotic-resistant strains and heterologous serotypes limit their effectiveness. …”
Get full text

CAR-T cells and TRUCKs that recognize an EBNA-3C-derived epitope presented on HLA-B*35 control Epstein-Barr virus-associated lymphoproliferation by Michael Hudecek, Anna Christina Dragon, Katharina Zimmermann, Thomas Nerreter, Deborah Sandfort, Julia Lahrberg, Stephan Klöß, Christina Kloth, Caroline Mangare, Agnes Bonifacius, Sabine Tischer-Zimmermann, Rainer Blasczyk, Britta Maecker-Kolhoff, Barbara Uchanska-Ziegler, Hinrich Abken, Axel Schambach, Britta Eiz-Vesper

“…IL-12, secreted by TRUCKs on target contact, was further tested for its chemoattractive and activating potential towards monocytes and natural killer (NK) cells.Results After co-cultivation with EBV target cells, TÜ165 CAR-Ts and TRUCKs showed an increased activation marker expression (CD137, CD25) and release of proinflammatory cytokines (interferon-γ and tumor necrosis factor-α). …”
Get full text