Bleomycin: A worthy alternative by Gursev Sandlas, Paras Kothari, Parag Karkera, Abhaya Gupta

“…Context : Lymphangiomas are developmental anomalies presenting mainly in the first two years of life. …”
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Shifting of Distribution and Changing of Antibiotic Resistance in Gram-Positive Bacteria from Bile of Patients with Acute Cholangitis by Hao Y, Li L, Du W, Lu J

“…Yuqi Hao,1 Lianxin Li,2 Wenting Du,1 Jinshuai Lu1 1Department of General Internal Medicine, People’s Hospital of Xinjiang Uygur Autonomous Region, Urumqi, Xinjiang, People’s Republic of China; 2Endoscopy Center, People’s Hospital of Xinjiang Uygur Autonomous Region, Urumqi, Xinjiang, People’s Republic of ChinaCorrespondence: Jinshuai Lu, Department of General Internal Medicine, People’s Hospital of Xinjiang Uygur Autonomous Region, Urumqi, Xinjiang, People’s Republic of China, Email lujinshuai@xjrmyy.comBackground: Gram-negative bacteria are the predominant pathogens responsible for biliary infections; however, the prevalence of Gram-positive bacteria is currently increasing. Investigating the bacterial spectrum and evolving antibiotic resistance patterns of Gram-positive bacteria is crucial for optimizing the management of acute cholangitis, particularly in the context of the global rise in antibiotic resistance.Methods: This retrospective analysis focused on Gram-positive bacteria isolated from the bile of patients undergoing biliary drainage with acute cholangitis at our hospital from January 1, 2018, to March 31, 2024. …”
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Meta-analysis on the effects of chemical stressors on freshwater ecosystem functions by Alexander Feckler, Ralf Schulz, Ralf B. Schäfer

“…Conclusions Our analyses demonstrate the potential to derive chemical stress–ecosystem function relationships from currently available data, which already reveal adverse effects on specific ecosystem functions. …”
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A Sociological study of the Relationship between Smartphone Addiction and Phubbing Case Study18-29 Year Old Females of Ramhormoz City by Ali Boudaghi, Ali Hossein Hosseinzadeh, Sayedeh Sara Mousavi Moghadam

“…The statistical population of the current research includes all women aged 18 to 29 in Ramhormoz city. …”
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The implementation of Safety Management Systems in healthcare: a systematic review and international comparison by Zhivko Zhelev, Sian de Bell, Alison Bethel, Maria Clarke, Rob Anderson, Jo Thompson Coon

“…Safety management systems need to be context-specific to be effective. Evidence on the use of safety management systems in health care is therefore needed to inform policy decisions. …”
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A virus becomes a global concern: research activities on West-Nile virus by Doris Klingelhöfer, Markus Braun, Isabelle M. Kramer, Friederike Reuss, Ruth Müller, David A. Groneberg, Dörthe Brüggmann

“…Currently, West-Nile virus (WNV) is spreading worldwide to colder regions due to climate change. …”
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Two decades of cropland monitoring in Changsha-Zhuzhou-Xiangtan city group: trends and future predictions by Wenbo Zhang, Dazhao Fan, Song Ji, Yang Dong, Dongzi Li, Ming Li

“…Rapid urbanization currently poses a threat to cropland areas. Therefore, exploring the pattern of change in cropland areas and its driving mechanism is of great significance in safeguarding regional economic development and food security. …”
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Contrasting Effect of Curcumin on Hepatitis B Virus Replication According to the Hepatoma Cell Line by María Mercedes Elizalde, Pedro Fuentes, Diego Chiappetta, Diego Martín Flichman

“…In recent decades, considerable advances have been achieved in the treatment of chronic hepatitis B. However, the currently available drugs have shortcomings. In this context, several natural compounds have been proposed as potential agents to improve either the outcome of antiviral treatment or the progression of chronic infection, with curcumin being one of the most evaluated compounds due to its pleiotropic antiviral activity. …”
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Enhanced recovery pathway for older people with hip fracture and cognitive impairment in acute hospitals: the PERFECTED research programme including an RCT by Chris Fox, Simon P Hammond, Lee Shepstone, Fiona Poland, Catherine Henderson, Tamara Backhouse, Bridget Penhale, Simon Donell, Martin Knapp, Douglas Lewins, Alasdair MacLullich, Martyn Patel, Opinder Sahota, Toby O Smith, Justin Waring, Jane L Cross

“…We collected front-line national and international healthcare professional perspectives on best practice, current practice and explanations for implementation gaps between ‘best’ and ‘current’ practice (WP1, phase 2). …”
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Kavalactones support motivation to move during intensive training in males preparing for military special operations forces by Sheena Y. Smith, Carlos F. Aylwin, Tyler F. Daniels, Jennifer L. Greer, Laura J. Kunces, Loukia Lili, Stephen M. Phipps, Caleb M. Schmidt, Julian C. Schmidt, Michael A. Schmidt

“…Furthermore, the group taking kavalactones first never experienced a significant decrease in Move motivation state (lowest mean score 21.0, highest 28.6, all p ≥ 0.05), while the group receiving kavalactones in the last 2 weeks of the study had Move scores that were statistically lower than baseline (lowest mean score 8.6, highest 25.9, all p ≤ 0.05) at all time points but the last (p = 0.063) after 2 weeks of kavalactones exposure.Conclusions We report a novel finding that kavalactones may support performance by maintaining or rescuing the desire to expend energy in the context of significant physical and mental strain in well-conditioned individuals, even in a context of already normal cortisol, sleep, and mood.…”
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Bleomycin: A worthy alternative by Gursev Sandlas, Paras Kothari, Parag Karkera, Abhaya Gupta

“…Context: Lymphangiomas are developmental anomalies presenting mainly in the first two years of life. …”
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Unveiling biomarkers via plasma metabolome profiling for diabetic macrovascular and microvascular complications by Zhixi Li, Yuhan Ren, Feng Jiang, Kai Zhang, Xuan Meng, Yingfeng Zheng, Mingguang He

“…Abstract Background Metabolic dysregulation plays a crucial role in the development of diabetic vascular complications. Current models for diabetic vascular complications predominantly rely on three conventional parameter classes: demographic characteristics, clinical measures, and standard laboratory indices. …”
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Interleukin-35 impairs human NK cell effector functions and induces their ILC1-like conversion with tissue residency features by Valentin Picant, Lara Revol-Bauz, Laurie Tonon, Timothée Casini, Aurélien Voissière, Dominique Poujol, Emilie Picard, Céline Rodriguez, Cyril Degletagne, Emily Sible, Uzma Hasan, Anthony Ferrari, Christophe Caux, Nathalie Bendriss-Vermare

“…Abstract Natural Killer (NK) cells play pivotal immunological roles including direct cytotoxic effector function and secretion of inflammatory and immunomodulating cytokines. In the context of chronic inflammation, NK cell fitness decreases during disease progression through currently unknown mechanisms. …”
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Outcomes following single level posterior lumbar fusion in patients with systemic and discoid lupus: A retrospective national database study by Meera M. Dhodapkar, MD, MHS, Scott J. Halperin, MD, MHS, Wesley Day, BA, Comron Saifi, MD, Daniel R. Rubio, MD, Fotios Koumpouras, MD, Jonathan N. Grauer, MD, Arya Varthi, MD

“…ABSTRACT: Background context: Posterior lumbar fusion (PLF) is a common procedure, for which patients with systemic conditions may be considered. …”
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Presentation of Financial Assets in the Statistics of Foreign Economic Relations by V. N. Salin, L. Yu. Arhangelskaya, O. G. Tretyakova

“…The paper identifies the main directions for the statisticalstudy of financial assets, based on current international standards, taking into account national practice. …”
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Iran's Media Diplomacy Challenges in Tourism Marketing by Fateme Asgharian Kari, Sajad Ferdowsi

“…Abstract The current research was conducted with the aim of identifying the challenges of Iran's media diplomacy in tourism marketing. …”
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Changes in the Species Composition and Structure of Large-Diameter Trees Along a Narrow Latitudinal Gradient in Subtropical China by Mengxian Li, Fei Huang, Xiaorong Jia

“…Investigating these impacts provides critical insights for silvicultural species selection and forest structure optimization, particularly in the context of global warming, and is essential for the sustainable development of large-diameter forests. …”
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Reassessing immediate coal phase-out: Dual imperatives of capacity control and renewables expansion in China’s net-zero strategy by Jiaxing Wang, Xi Lu, Hao Wang, Yang Ou, Jianxiao Wang, Dan Tong, Yan Li, Ziwen Ruan, Zihua Yin, Wenlong Zhou, Benjamin McLellan, Emily Xing, Anna M. MacLennan, Jingli Fan, Xian Zhang, Michael B. McElroy, Kebin He

“…Broader context: Reducing CO2 emissions in power systems is crucial for China in achieving its net-zero emission target. …”
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Effects of El Niño and the Positive Indian Ocean Dipole (+IOD) on Health, Food Security, Economics, and Conflict in Low‐ and Middle‐Income Countries in the Indo‐Pacific: A Systemat... by Andrea Floridi, María Daniela Anda‐León, Tomasz Kozakiewicz, Megha Bhattacharyya, Anilkrishna Thota, Peter Burt, Luca Tasciotti, Jan Selby, Zahra Premji, Shannon Shisler

“…ABSTRACT Climate drivers such as the El Niño Southern Oscillation (ENSO) and the Indian Ocean Dipole (IOD) can impact multiple sectors globally. We are currently witnessing the effects of these teleconnections against the backdrop of a changing climate. …”
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Helminth Coinfections Modulate Disease Dynamics and Vaccination Success in the Era of Emerging Infectious Diseases by Brice Armel Nembot Fogang, Linda Batsa Debrah, Michael Owusu, George Agyei, Julia Meyer, Jonathan Mawutor Gmanyami, Manuel Ritter, Kathrin Arndts, Derrick Adu Mensah, Tomabu Adjobimey, Achim Hörauf, Alexander Yaw Debrah

“…<b>Methods</b>: This systematic review conducted in line with the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) 2020 guidelines synthesizes the current evidence, identifies patterns, and highlights areas needing further research, offering a cohesive understanding of the topic. …”
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