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1341
Caregivers and multidisciplinary team members’ perspectives on shared decision making in Duchenne muscular dystrophy: A qualitative study
Published 2025-03-01“…Abstract Background As new therapies for Duchenne muscular dystrophy (DMD) are entering the market, shared decision making (SDM) will become increasingly important. Therefore, this study aimed to understand (1) Belgian stakeholders’ knowledge and perceptions of SDM in DMD treatment decision making, (2) the current state of SDM implementation in DMD in Belgium, examining the role of all involved parties, and (3) the barriers and facilitators for SDM in DMD in the Belgian context. …”
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1342
Heating Sector Strategies in Climate-Neutral Societies
Published 2025-01-01“…The results of the analyses show (1) a feasible reduction level of around 36% in end-use heat demand in buildings, with higher potential in older buildings and lower in new buildings, (2) expanding district heating to areas with a density of 15-10 kWh/m2 is feasible, resulting in a district heating share of 63-70% of the heat demand compared to the current level of 51%, (3) a large unexploited potential to use heat sources such as industrial excess heat, geothermal heat, data centres and power-to-X, reducing the need for biomass in the heating sector, and (4) increased use of variable renewable energy and combined heat and power production increasing gas export and thus replacing biomass consumption outside the country. …”
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1343
Oligomerization of the Clostridioides difficile transferase B component proceeds through a stepwise mechanism.
Published 2025-07-01“…Clostridioides difficile is a gram-positive, pathogenic bacterium and is currently the leading cause of hospital-acquired, infectious diarrhea in the United States. …”
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1344
Nursing regulation in Canada: Insights from a scoping review.
Published 2025-01-01“…The number of publications has steadily increased over the last few decades, and the majority of sources were situated in a provincial/territorial context (n = 104, 53.3%), followed by the national (n = 67, 34.4%) and global context (n = 24, 12.3%). …”
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1345
Τhe Political Economy of Green Transition: The Need for a Two-Pronged Approach to Address Climate Change and the Necessity of “Science Citizens”
Published 2025-01-01“…The principal results and findings offer interpretations and insights while encouraging further discussion on transitioning to a sustainable science society. In this context, the analysis results elucidate that there is evidence for an increased policy emphasis on technology development (economy-based approaches) rather than on technology diffusion and assessment, and/or the integration of key small-scale actors, such as citizens. …”
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1346
Diagnostic Challenges in Fungal Coinfections Associated With Global COVID-19
Published 2025-01-01“…The early diagnosis of opportunistic infections is a critical concern for patient care worldwide, particularly in the context of the COVID-19 pandemic. This review examines the challenges and advancements in the management and early diagnosis of opportunistic fungal infections, which have become increasingly prominent during the pandemic. …”
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1347
Therapeutic and legal aspects of psilocybin in cancer-related depression
Published 2025-08-01“…Depression prevalence is markedly elevated in oncological patients, particularly among head and neck cancer (HNC) cohorts, who face twice the prevalence of major depressive disorder (MDD) compared to other cancer populations. MDD in this context independently predicts poorer clinical outcomes and increased morbidity. …”
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1348
The development of group healing storytelling model in multicultural counselling services in Indonesian schools: Examination of disciplinary cases
Published 2021-04-01“…However, it is limited to a cultural context, so it will be complicated to implement it in a different cultural environment.…”
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1349
Climate change reduces warming potential of nitrous oxide by an enhanced Brewer‐Dobson circulation
Published 2016-06-01“…N2O is a potent greenhouse gas and the most relevant currently emitted ozone‐depleting substance. Here we examine the implications of a reduced N2O lifetime in the context of climate change. …”
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1350
ISSUES AND TRENDS OF PROGRESS TOWARDS SUSTAINABLE DEVELOPMENT GOALS IN ROMANIA
Published 2020-01-01“…Monitoring SDG 12 in an EU context focuses on progress made in decoupling environmental impacts from economic growth, in decreasing energy consumption and in tackling waste generation and management. …”
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1351
The effects of seismic activities following the 30 October 2020 Samos Island earthquakes in Izmir and its surrounding
Published 2024-12-01“…In this context, in order to determine the current deformation after the Samos Island earthquake that occurred on October 30, 2020, measurements were performed at six continuous GNSS stations in and around Izmir. …”
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1352
Bleomycin: A worthy alternative
Published 2011-01-01“…Complications of the therapy were few and far between. 2 patients developed fever after injection, one patients reported a transient increase in size of swelling, 2 patients have developed discoloration of the overlying skin and are currently being followed up for final outcome. …”
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1353
Meta-analysis on the effects of chemical stressors on freshwater ecosystem functions
Published 2025-07-01“…Importantly, the shape and direction of the relationships identified here match those reported in field-based studies, indicating a decrease in functioning as chemical stress increases, strengthening the ecological relevance of our findings. …”
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1354
Cell Therapy in Ischemic Heart Disease: Interventions That Modulate Cardiac Regeneration
Published 2016-01-01“…This review brings together current data on pharmacological and nonpharmacological approaches to improve cell homing and cardiac repair.…”
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1355
Blood-based biomarkers in mild behavioral impairment: an updated overview
Published 2025-02-01“…A growing number of studies have recently begun to explore the relationship between MBI and several blood-based biomarkers associated with Alzheimer’s disease (AD) pathology, neurodegeneration, as well as systemic metabolic and inflammatory dysregulation. In this context, MBI has been associated with lower plasma Aβ42/Αβ40 ratio, higher plasma phosphorylated tau at threonine 181 (p-tau181), increased neurofilament light chain (NfL) levels, as well as disturbances in metabolic markers, including homocysteine, insulin and ferritin, suggesting a multifaceted neurobiological basis for this syndrome. …”
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1356
The Role of Extracellular Vesicles in Aging and Age-Related Disorders
Published 2025-02-01“…Mitochondrial malfunction and increased oxidative stress are major contributors for the aging process. …”
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1357
Assessment of Health-Oriented Layout and Perceived Density in High-Density Public Residential Areas: A Case Study of Shenzhen
Published 2024-11-01“…The authors attempt to go beyond current regulations to propose tailored solutions for Shenzhen’s high-density context, improving spatial efficiency and residential comfort in future public housing designs. …”
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1358
The frequent variant A57F in the GNE gene in patients from Russia has Finno-Ugric Mari origin
Published 2024-12-01“…According to our study, the estimated age of the mutation’s spread is 160.46 years (95% CI: 45.55–244.14).DiscussionBy comparing the information gathered with historical data on migration patterns in the Middle Volga region and estimating the age of the variant’s dissemination, we propose hypotheses regarding its origin and the pathways through which it spread. In the current context of increased rate of interethnic marriages, investigating the spread of common pathogenic variants from historically isolated populations is important for molecular genetic diagnosis. …”
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1359
The PRE‐registration podiatry: Accessible recruitment and employment (PREPARE) project: A commentary on the novel approach to the podiatry workforce crisis in Glasgow
Published 2024-12-01“…This paper explores the local context of the current workforce challenges and summarises a novel solution collaboratively developed in Glasgow. …”
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1360
A Review of the Insider Threat, a Practitioner Perspective Within the U.K. Financial Services
Published 2024-01-01“…The insider threat within organisational cybersecurity continues to be of great concern globally. The current insider threat detection strategies are acknowledged as ineffective, evidenced by the increased reported events in high-profile insider threats and cyber data loss cases borne from insider and privilege misuse. …”
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