Pharmacological and pupillary evidence for the noradrenergic contribution to reinforcement learning in Parkinson’s disease by Claire O’Callaghan, Frank H. Hezemans, Naresh Subramaniam, Rong Ye, Kamen A. Tsvetanov, Alexander G. Murley, Negin Holland, Isabella F. Orlando, Ralf Regenthal, Roger A. Barker, Caroline H. Williams-Gray, Luca Passamonti, Trevor W. Robbins, James B. Rowe

“…Testing the noradrenergic framework of learning in the context of human diseases offers a test bed for current normative neuroscience theories and may also indicate therapeutic potential. …”
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Traumatic Brain Injury and Genetic Risk for Alzheimer’s Disease Impact Cerebrospinal Fluid β-Amyloid Levels in Vietnam War Veterans by Jena N. Moody, Erica Howard, Kate E. Nolan, Sarah Prieto, Mark W. Logue, Jasmeet P. Hayes

“…This relationship may be stronger with increasing TBI severity (p = 0.05). Overall, TBI was associated with lower Aβ42/40, indicating greater amyloid deposition in the brain, in the context of greater polygenic risk for AD. …”
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Unravelling the myriad physiologic roles of transthyretin: critical considerations for treating transthyretin amyloidosis by Morie A. Gertz, Mandar A. Aras, Nicole Bart, Thomas H. Brannagan, Jan M. Griffin, Amy R. Kontorovich, Andrew M. Rosen

“…While a link between low TTR and severe disease and mortality is well established, it remains unclear whether long-term TTR suppression via ATTR therapies increases risk of disease. Clinical decisions in ATTR, however, should reflect the current understanding of the roles of TTR and the patient’s clinical history.Conclusion TTR serves vital physiologic roles across organ systems. …”
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Climate change adaptation: policy, practice and adaptation gaps in the agriculture sector in Bangladesh, India and Nepal by Shobha Shrestha, Prem Sagar Chapagain, Yili Zhang, Linshan Liu, Jianzhong Yan, Suresh Chand Rai, Md. Nurul Islam, Basanta Paudel

“…Lack of understanding and awareness of CCA in a local sociocultural context among implementation authorities and weak institutional mechanisms are gaps at the institutional front. …”
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Potential protective association of the AA genotype and a allele of CXCR4 rs2228014 polymorphism with COVID-19 severity in adult egyptians by Osama H. Korayem, Amr E. Ahmed, Mohamed H. Meabed, Doaa M. Magdy, Wafaa M. Abdelghany

“…Several genetic factors have been implicated in diverse responses to SARS-CoV-2 infection, such as the C-X-C chemokine receptor 4 (CXCR4) rs2228014 polymorphism, which has been previously studied in various diseases but has not been explored in the context of COVID-19 severity. The current study aimed to assess the association between the rs2228014 polymorphism in the CXCR4 gene and the severity of COVID-19, which has not been previously reported. …”
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Quantitative systems toxicology modeling in pharmaceutical research and development: An industry‐wide survey and selected case study examples by Kylie A. Beattie, Meghna Verma, Richard J. Brennan, Diana Clausznitzer, Valeriu Damian, Derek Leishman, Mary E. Spilker, Britton Boras, Zhenhong Li, Elias Oziolor, Theodore R. Rieger, Anna Sher

“…Abstract Quantitative systems toxicology (QST) models are increasingly being applied for predicting and understanding toxicity liabilities in pharmaceutical research and development. …”
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Private, non-profit, and plantation: Oil palm smallholders in management-assistance programs vary in socio-demographics, attitudes, and management practices. by Valentine J Reiss-Woolever, Wakhid Wakhid, Muhammad Ikhsan, Jean-Pierre Caliman, Muhammad Naim, Elfina N Azmi, Sharyn Shufiyan, John Howes, Reza Azmi, Ying Ying Lim, Siti Zulaikah Abdul Jan, Isaac Barrock, Badrul Azhar, Julia Drewer, Caroline Ward, Joshua A Jones, Sarah H Luke, Edgar C Turner, Purnama Hidayat, Damayanti Buchori

“…Awareness of the effects of palm oil production on ecosystems and human communities has increased drastically in recent years, with ever louder calls for the private and public sector to develop programs to support sustainable cultivation by smallholder farmers. …”
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Identity and engagement in networked Open Educational Practice by Katerina Zourou

“…To unleash the potential of OER, current research lays emphasis on Open Educational Practice (OEP), as the (re-)use of open resources in learning and teaching contexts. …”
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Identifying practices of information transfer between the hospital and primary care for older adults: a scoping review protocol by Philippe Desmarais, Claire Godard-Sebillotte, Thomas Tannou, Emily G. McDonald, Dounia Rouabhia, Géraldine Layani, Dimitri Yang, Martina Alkot, Andrea Quaiattini, Sabrina Lessard, Aigul Zaripova, Carolyn Pavoni, Sandrine Couture, Yu Qing Huang, Catherine Richer, Julia Chabot, Felix Pageau, Matthieu Calafiore, Karin Fink, Gulin Yilmaz, Beuscart Jean-Baptiste

“…Information transfer practices are heterogeneous, in some places depending on individual initiative and sometimes not occurring at all.To improve current practices, we will conduct a scoping review to identify the current and suggested practices of information transfer between hospital-based physicians or pharmacists and the primary care team of older patients.Methods and analysis This scoping review will be conducted using Arksey and O’Malley’s methodological framework, augmented by Levac et al and the JBI Manual for Evidence Synthesis, and the findings reported according to the PRISMA extension for Scoping Reviews. …”
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Burnout and its Factors in Healthcare Workers Involved in Providing Health Care for Patients With COVID-19 at Different Stages of the Pandemic by A. B. Kholmogorova, S. S. Petrikov, A. Y. Suroyegina, O. Y. Mikita, A. A. Rakhmanina, A. P. Roy

“…Abstract. In the context of the pandemic, when healthcare professionals are forced to work under extreme stress and an increased threat of infection, research on professional burnout and emotional maladjustment of medical workers is gaining particular relevance around the world.Aim of study. …”
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Credit Rationing Equilibrium Achievement in the Conditions of Digitalization by O. V. Lunyakov

“…The authors’ hypothesis is that the credit market has the potential to increase the return on a loan per currency unit of borrowers’ loans, and the current estimates of the of defaults borrowers’ probability, interest rates are “biased”. …”
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Presentation of Financial Assets in the Statistics of Foreign Economic Relations by V. N. Salin, L. Yu. Arhangelskaya, O. G. Tretyakova

“…Together with the financial account, account figures for other changes in financial assets and liabilities explain the total amount of changes: increases or decreases in the value of financial assets / liabilities, their occurrence or disposal, resulting from transactions, revaluation and other changes in volume.The issues of theory and practice of presenting indexes of financial assets in the considered sections of macrostatistics and their analysis are a relevant and promising direction for improving national statistical accounting, incl. due to the spread of remote work, the collection of information via the Internet, the emergence of a large number of new financial instruments and operations.The authors of the article have repeatedly referred to the problems of macroeconomic financial statistics in their studies, which gave them the opportunity to comprehensively consider the topical issues of representing financial assets in the statistics of foreign economic relations.…”
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The limits of learning engagement and academic leadership within the higher education digitalization process - analysis by using PLS SEM. by Ioana Gutu, Camelia Nicoleta Medeleanu, Romeo Asiminei

“…The current paper considers the changes in the learners' engagement in the context of the dually digital transformation of the higher academic multi-institutional digitally-learning enhancements. …”
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Cervical ripening at home or in hospital during induction of labour: the CHOICE prospective cohort study, process evaluation and economic analysis by Mairead Black, Cassandra Yuill, Mairi Harkness, Sayem Ahmed, Linda Williams, Kathleen A Boyd, Maggie Reid, Amar Bhide, Neelam Heera, Jane Huddleston, Neena Modi, John Norrie, Dharmintra Pasupathy, Julia Sanders, Gordon C S Smith, Rosemary Townsend, Helen Cheyne, Christine McCourt, Sarah Stock

“…However, there was substantial uncertainty with the adjusted analysis consistent with a 74% decrease in the risk through to an 81% increase. qCHOICE Important aspects of service users’ experience of home cervical ripening were quality of information provided, support and perception of genuine choice. …”
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Leadership styles and quality of work life in SMEs by T. S. Nanjundeswaraswamy, D.R. Swamy D R

“…Small and Medium Enterprises (SMEs) in India are currently facing the challenges of increased competitions. …”
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Repurposing Cyclic Guanosine Monophosphate Pathway Medications, from Vasodilation toward Changing the Face of Heart Failure by Antoine Fakhry AbdelMassih, Buthaina Ramadan, Jana Tarek ElDemerdash, Monia Mostafa Zayed, M. Wasim Soued, Nadine El-Husseiny, Yousef M. Husseiny, Passant Saad

“…Among the most commonly used medications used in this context, is milrinone, which increases the myocardial relaxation velocity, what is known as lusitropy. …”
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Esenin’s Reception in Russia and Abroad by Maxim V. Skorokhodov

“…The conference will result in Esenin’s encyclopedia, currently in progress.…”
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The impact of e-marketing orientation, technological orientation and learning capacity on online SME performance by Ahmed Al Asheq, Khadiza Rahman Tanchi, Md. Kamruzzaman, Md. Mobarak Karim

“…Currently, Internet penetration is accelerating across the country in Bangladesh, which, in particular, has led to the simultaneous development and growth of online businesses. …”
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Mind the semantic gap: semantic efficiency in human computer interfaces by James Horsley

“…Current ML systems have fundamental semantic gaps in bespoke human context, real-time world knowledge, and how those relate to HCI tooling. …”
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The implementation of Safety Management Systems in healthcare: a systematic review and international comparison by Zhivko Zhelev, Sian de Bell, Alison Bethel, Maria Clarke, Rob Anderson, Jo Thompson Coon

“…Approaches to patient safety in all countries reflect increasing awareness that for an initiative to be successful, it needs to be context-specific. …”
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