Overcoming immunosuppression in cancer: how ketogenic diets boost immune checkpoint blockade by Victoria E. Stefan, Daniela D. Weber, Roland Lang, Barbara Kofler

“…., high-fat low-carbohydrate diets, have been shown to have antiproliferative and immunomodulatory effects in various preclinical cancer studies. Here, we review current knowledge of the complex interplay of KDs and the anti-tumor immune response in the context of ICB therapy, to update our understanding of diet-induced immunometabolic reprogramming in cancer. …”
Get full text

Horticultural performance and QTL mapping of snap bean (Phaseolus vulgaris L.) populations with organic and conventional breeding histories by Hayley E. P. Richardson, Ryan M. King, Joel Davis, James R. Myers

“…IntroductionImproving crop cultivars for use on organic farms is pertinent, as current elite germplasm is less resilient within the more variable context of organic farm environments. …”
Get full text

Transition resistance influence of the upper structure track ballast on the rail-to-earth potential at AC railway sections by A. A. Krylov, I. A. Rebrov, A. V. Rudashevskaya, R. A. Rudashevskiy, E. D. Khar'kovskaya

“…This section includes the heavy freight traffic with the increased electric resistance of the track ballast by the upper structure redevelopment.Results. …”
Get full text

Investigation of island size effect on radiation distribution during attached and detached plasmas in the island divertor of W7-X by B.J. Peterson, G. Partesotti, F. Reimold, G.A. Wurden, Y. Gao, D. Zhang, V. Winters, M. Kobayashi, Y. Feng, K. Mukai, J. von Miller

“…W7-X employs an island divertor to control the exhaust and heat load on the plasma impacting divertor plates. Increased radiation in the divertor reduces the heat load at the plasma contact point during detachment. …”
Get full text

High proportion of depression and anxiety in younger patients with COPD: a cross-sectional study in primary care in Sweden by Therese Öfverholm, Mikael Hasselgren, Karin Lisspers, Anna Nager, Gabriella Eliason, Maaike Giezeman, Christer Janson, Marta A. Kisiel, Scott Montgomery, Björn Ställberg, Josefin Sundh, Hanna Sandelowsky

“…Background and aim Patients with COPD and concurrent depression and/or anxiety are known to have an increased risk of exacerbations, morbidity, mortality, and deteriorated quality of life. …”
Get full text

Modification of PEDOT:PSS films using ZnI2 additive for power conversion efficiency enhancement of organic solar cells by Sucheewan Krobthong, Sutthipoj Wongrerkdee, Sawitree Wongrerkdee, Khathawut Lohawet, Anusit Kaewprajak, Pisist Kumnorkaew

“…This behavior causes lower sheet resistance and results in an increased Jsc and Voc for OSC devices. Therefore, the improved interfacial contact and depletion of PSS are considered synergistic functions for OSC enhancement.…”
Get full text

Impact of Patient Online Record Access on Documentation: Scoping Review by Eva Meier-Diedrich, Camilla Lyckblad, Gail Davidge, Maria Hägglund, Anna Kharko, Brian McMillan, Charlotte Blease, Julian Schwarz

“… BackgroundOnline record access (ORA) is being increasingly implemented internationally. Despite reported benefits for patients, health care professionals (HCPs) have raised concerns about potential disadvantages. …”
Get full text

Illuminating Bilateral Breast Cancer: A Multicenter Experience and Clinical Observations by Berkan Karabuğa, Mustafa Büyükkör, Ekin Konca Karabuğa, Sedat Yıldız, Mirmehdi Mehtiyev, Havva Yeşil Çınkır, Sıla Soylu Koçoğlu, Hacer Demir, Ozan Yazıcı, Doğan Uncu, Ömür Berna Öksüzoğlu, Ülkü Yalçıntaş Arslan

“…In multivariate regression analysis, hormone receptor negativity was identified as an independent risk factor for decreased DFS among all BBC patients. Our study is noteworthy for shedding light on the clinical features of BBC in the context of current knowledge and for its multicenter design.…”
Get full text

Heavy Metal Bioremediation Potential of Autochthonous Lactic Acid Bacteria for Use in Edible Leafy Vegetables by Mahdieh Mostafidi, Mohammad Reza Sanjabi, Naheed Mojgani, Sohyel Eskandari, Sepideh Arbabi Bidgoli

“…During in vitro analysis, the sorption percentage of Pb and Cd appeared higher than 99% during 15 minutes of initial contact, while increasing contact time (30 minutes) had no significant effect on the removal of these metals. …”
Get full text

Canine Distemper Virus in Mexico: A Risk Factor for Wildlife by Juan Macías-González, Rebeca Granado-Gil, Lizbeth Mendoza-González, Cesar Pedroza-Roldán, Rogelio Alonso-Morales, Mauricio Realpe-Quintero

“…Canine distemper is caused by a morbillivirus similar to others that affect livestock and humans. The increase in host range and its persistence in wildlife reservoirs complicate eradication considerably. …”
Get full text

Repetitive transcranial magnetic stimulation for the treatment of suicidality in opioid use disorder: a pilot feasibility randomized controlled trial by Victor M. Tang, Bernard Le Foll, Zafiris J. Daskalakis, An-Li Wang, Leslie Buckley, Daniel M. Blumberger, Daphne Voineskos

“…Conclusion We present the first data piloting a structural neuroimaging-guided, multi-session rTMS treatment course in outpatients with suicidality and OUD in the current North American context. Recruitment and retention were the main challenges given the highly unstable medical and psychosocial context of this patient population. …”
Get full text

Urogenital Schistosomiasis among Schoolchildren and the Associated Risk Factors in Selected Rural Communities of Kwara State, Nigeria by Babamale Olarewaju Abdulkareem, Kolawole Olasunkanmi Habeeb, Abdulganiyu Kazeem, Abdulkareem Olaitan Adam, Ugbomoiko Uade Samuel

“…Similarly, infection significantly (P<0.05) increased with increasing age. Multivariate logistic analysis of risk factors revealed that lack of portable drinking water (adjusted odd ratio (aOR) = 4.76; 95% CI = 2.64–5.98), unemployment (aOR = 2.23; 1.87–2.294), lack of knowledge of infection (aOR = 2.16; 0.59–3.83), and frequent contact with contaminated water bodies (aOR = 2.01; 1.45–2.70) were important predictors of urinary schistosomiasis. …”
Get full text

NLFEA Behavior of Heat-Damaged Key Joints in Precast Concrete Segmental Bridge by Bara’a R. Alnemrawi, Rajai Al-Rousan

“…It has been found that the initial stiffness, ultimate deflection, and ultimate strength values were all increased under increasing confinement pressure. Moreover, the situation is totally different when the exposure temperature exceeds 400 °C. …”
Get full text

A Systematic Review on Selected Complications of Open-Wedge High Tibial Osteotomy from Clinical and Biomechanical Perspectives by Elaheh Elyasi, Guillaume Cavalié, Antoine Perrier, Wilfrid Graff, Yohan Payan

“…The posterior tibial slope significantly increases, and the patellar height (using the Blackburne-Peel ratio) significantly decreases in the majority of the selected studies. …”
Get full text

Evaluation of the Efficacy of UV-C Radiation in Eliminating <i>Clostridioides difficile</i> from Touch Surfaces Under Laboratory Conditions by Anna Różańska, Anna Pioskowik, Laura Herrles, Tanisha Datta, Paweł Krzyściak, Estera Jachowicz-Matczak, Tomasz Siewierski, Monika Walkowicz, Agnieszka Chmielarczyk

“…The adoption of UV-C as a supplementary disinfection method in hospitals has significantly increased since the COVID-19 pandemic. However, there are no current guidelines concerning the use of UV-C disinfection in hospitals. …”
Get full text

Study of the magnetic field effect on partial discharges characteristics by D. A. Polyakov, M. A. Kholmov, K. I. Nikitin

“…The modeling has shown that if the operational electrical strength of the current transformer insulation is present, the high-voltage potential cannot contact the current flow circuit. …”
Get full text

Hypoxia-inducible factor-1α promotes tubulointerstitial fibrosis via the upregulation of Muc4 by Zhong-Tang Li, Xin-Hui Hu, Wei-Jie Ni, Zuo-Lin Li, Bi-Kun Huang, Yu Zhang, A-Feng Miao, Jing-Yuan Cao

“…Furthermore, MUC4 overexpression in the context of HIF-1α knockout was positively correlated with increased ECM protein expression and TIF. …”
Get full text

Job insecurity, work passion, and work–life balance in diverse work arrangements by Chantell Ribas, Gerhard H. Rabie, Karina Mostert, Leon De Beer

“…Orientation: The coronavirus disease 2019 (COVID-19) pandemic shifted work settings, revealing gaps in current literature on how work arrangements affect employee experiences and well-being. …”
Get full text

A comprehensive study on thermal/electrical conduction, mechanical and curing properties of silicone rubber nanocomposites contained exfoliated-surface modified h-BNs by Atefe Farahani, Masoud Jamshidi, Masumeh Foroutan

“…This happening improved filler-polymer adhesion and made the mechanical property of the modified nanocomposite outstanding with higher storage modulus, tensile strength and Tg compared to the SR (i.e. 127%, 26% and 10 °C, respectively). The contact angle increased from 92.8o for SR to 107.6 for modified nanocomposite which is mostly desired in microelectronic applications.…”
Get full text

Application of IVDr NMR spectroscopy to stratify Parkinson’s disease with absolute quantitation of blood serum metabolites and lipoproteins by Georgy Berezhnoy, Gyuntae Bae, Leonie Wüst, Claudia Schulte, Claire Cannet, Isabel Wurster, Milan Zimmermann, Alexander Jäck, Eike Jakob Spruth, Julian Hellmann-Regen, Sandra Roeske, Dominik Pürner, Wenzel Glanz, Fabian Maass, Felix Hufschmidt, Ingo Kilimann, Elisabeth Dinter, Okka Kimmich, Anna Gamez, Johannes Levin, Josef Priller, Oliver Peters, Michael Wagner, Alexander Storch, Paul Lingor, Emrah Düzel, Christoph van Riesen, Ullrich Wüllner, Stefan Teipel, Björn Falkenburger, Mathias Bähr, Inga Zerr, Gabor C. Petzold, Annika Spottke, Patricia Rizzu, Frederic Brosseron, Hartmut Schäfer, Thomas Gasser, Christoph Trautwein

“…Abstract The challenge of early detection and stratification in Parkinson’s disease (PD) is urgent due to the current emergence of mechanism-based disease-modifying treatments. …”
Get full text