EstablishINg the best STEp-up treatments for children with uncontrolled asthma despite INhaled corticosteroids (EINSTEIN): protocol for a systematic review, network meta-analysis a... by Ian Sinha, Dyfrig A Hughes, Michelle Maden, Stephen Turner, Sofia Cividini, Sarah Donegan, Giovanna Culeddu, Katie Rose, Olive Fulton, Catrin Tudur Smith

“…Treatment with a low-dose ICS, however, fails to control asthma symptoms in around 10%–15% of children and this places the individual at increased risk for an asthma attack. At present, there is no clear preferred treatment option for a child whose asthma is not controlled by low-dose ICS and international guidelines currently recommend at least three treatment options. …”
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Is drought protection possible without compromising flood protection? Estimating the potential dual-use benefit of small flood reservoirs in southern Germany by S. Q.-G. Ho, S. Q.-G. Ho, S. Q.-G. Ho, U. Ehret, U. Ehret

“…<p>As climate change drives the intensification and increased frequency of hydrological extremes, the need to balance drought resilience and flood protection becomes critical for proper water resources management. …”
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Against Futility Judgments for Patients with Prolonged Disorders of Consciousness by William Choi

“…Despite emerging empirical evidence of PDOC patients’ potential for long-term recovery, an increasing sense of clinical nihilism leads to earlier and more frequent withdrawal of LST. …”
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Spatio-temporal forecasting of COVID-19 cases in the Netherlands for source and contact tracing by Max Keuken, Jizzo R. Bosdriesz, Anders Boyd, Elisabeth M. den Boogert, Ivo K. Joore, Nicole H.T.M. Dukers – Muijrers, Gini van Rijckevorsel, Hannelore M. Götz, Irene E. Goverse, Mariska W.F. Petrignani, Stijn F.H. Raven, Susan van den Hof, Kirsten V.C. Wevers-de Boer, Maarten F. Schim van der Loeff, Amy Matser

“…Due to the rapid increases in incidence of COVID-19 in the Netherlands, the capacity to conduct a full SCT quickly became insufficient. …”
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Whole-blood model reveals granulocytes as key sites of dengue virus propagation, expanding understanding of disease pathogenesis by Hansa Praneechit, Somchai Thiemmeca, Dararat Prayongkul, Kessiri Kongmanas, Dumrong Mairiang, Nuntaya Punyadee, Adisak Songjaeng, Nattaya Tangthawornchaikul, Nasikarn Angkasekwinai, Kanokwan Sriruksa, Yupin Suputtamongkol, Wannee Limpitikul, John P. Atkinson, Panisadee Avirutnan

“…Current models for studying DENV pathogenesis often lack the complexity of the human immune system, hindering the development of effective therapies and vaccines. …”
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Direct oral penicillin challenge in secondary care with low-risk patients: the SPACE mixed-methods study with cost-effectiveness analysis by Mamidipudi Thirumala Krishna, Yogini H Jani, Iestyn Williams, Ruben Mujica-Mota, Rebecca Bestwick, Michele Siciliano, Robert Michael West, Rashmeet Bhogal, Bee Yean Ng, Kornelija Kildonaviciute, Rachel Pollard, Nicola Jones, Louise Dunsmure, Mairead McErlean, Neil Powell, Chidanand C Hullur, Ariyur Balaji, Jonathan Sandoe, Amena Warner, Ron Daniels, Caroline Thomas, Siraj A Misbah, Louise Savic

“…Penicillin allergy labels lead to increased risk for serious hospital infections and longer hospital stay and are associated with higher estimated healthcare costs. …”
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Analysis of Interdisciplinary Differences in the Structure of the Scientific Genre in the Introduction Section of Humanities Research Articles by Roya Peyravi, Hossein Ghorbanpoor Arani, Abbas Zaree

“…The findings of this research are both applicable and feasible for evaluating the current challenges in scientific writing. In this context, two key recommendations have been proposed to improve academic writing in the Persian language. …”
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Mineralogy and sulfide mineral chemistry of Khabr iron ore, Southwest of Baft (Southeast of Sanandaj-Sirjan Zone) by Mohammad Boomeri, Habib Biabangard, Somayeh Dehghani Soltani, Azadeh Bordbar

“…By dissolving carbonate rocks and increasing the pH, chloride complexes became unstable and magnetite replaced limestone. …”
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A study of the safety and immunogenicity of a new vaccine for the prevention of COVID-19 based on virus-like particles in phase I clinical trials by Tatiana V. Grebennikova, Olga N. Zaykova, Alexey A. Plotnikov, Lyudmila V. Kostina, Yana Yu. Chernoryzh, Olesia V. Eliseeva, Oleg E. Latyshev, Viktor F. Larichev, Irina T. Fedyakina, Milana A. Losich, Ilya M. Kirillov, Ilya E. Filatov, Marina V. Balandina, Valery V. Tsibezov, Kirill I. Yurlov, Ekaterina I. Lesnova, Valeria M. Kondratieva, Alina A. Kozlova, Marina S. Baranets, Aleksandr L. Gintsburg

“…One of the more promising developments in preventing the spread of infections, including COVID-19, is the production of vaccines based on virus-like particles (VLP). Currently, in the National Research Center for Epidemiology and Microbiology named after N.F. …”
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Role of NLRP3 Inflammasome in Heart Failure Patients Undergoing Cardiac Surgery as a Potential Determinant of Postoperative Atrial Fibrillation and Remodeling: Is SGLT2 Cotransport... by Rodrigo L. Castillo, Jorge Farías, Cristian Sandoval, Alejandro González-Candia, Esteban Figueroa, Mauricio Quezada, Gonzalo Cruz, Paola Llanos, Gonzalo Jorquera, Sawa Kostin, Rodrigo Carrasco

“…In heart failure (HF) patients undergoing cardiac surgery, an increased activity of mechanisms related to cardiac remodeling may determine a higher risk of postoperative atrial fibrillation (POAF). …”
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Identification of Writing Patterns, Motivations, and Barriers to Publishing Articles by Faculty Members in the Humanities Departments of the University of Tabriz in Perestigious In... by Hashem Atapour, Solmaz Zardary, Fereshteh Javadi

“…Accordingly, the publication of scientific outputs resulting from faculty research is currently a fundamental requirement and, in some cases, mandatory at universities. …”
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Unlocking Movement: How Wearables Transform Biomechanical Assessment and Rehabilitation by Tahir Masood

“…CONCLUSION Wearables have increasingly been used for biomechanical assessment and rehabilitation playing an important role in advancing personalized medicine in physical therapy. …”
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A novel in vitro system for simultaneous infections with hepatitis B, C, D and E viruses by Roxanne Fouillé, Eloi R. Verrier, Amse De Meyer, Lieven Verhoye, Maud Michelet, Romain Barnault, Caroline Pons, Olivier Diaz, Michel Rivoire, Guillaume Passot, Eike Steinmann, Heiner Wedemeyer, Anna Salvetti, Nicole Pavio, Virginie Doceul, Raphaël Darteil, Philip Meuleman, David Durantel, Julie Lucifora

“…Results: We observed increased expression of liver specific transcripts and production of ApoB containing VLDL in dHuH7.5-NTCP cells and replication of HBV, HDV, HCV and HEV for at least 4 weeks after mono or multiple infections. …”
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Addressing Shortcomings in Contingency Standards of Care by Alexander Quan

“…Lack of Formalization One shortcoming of current contingency measures is that they fail to meet the same level of procedural detail and clarity as crisis standards. …”
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Prevalence of smoking and its changes over time in Russia: data from the ESSE-RF study by O. M. Drapkina, S. A. Maksimov, S. A. Shalnova, Yu. A. Balanova, A. E. Imaeva, V. A. Kutsenko, G. A. Muromtseva, M. B. Kotova, N. S. Karamnova, S. E. Evstifeeva, A. V. Kapustina, A. A. Zelenina, O. A. Litinskaya, M. S. Pokrovskaya, E. B. Yarovaya, T. V. Repkina, T. O. Gonoshilova, A. V. Kudryavtsev, N. I. Belova, L. L. Shagrov, M. A. Samotrueva, A. L. Yasenyavskaya, E. N. Chernysheva, S. V. Glukhovskaya, I. A. Levina, E. A. Shirshova, E. B. Dorzhieva, E. Z. Urbanova, N. Yu. Borovkova, V. K. Kurashin, A. S. Tokareva, Yu. I. Ragino, G. I. Simonova, A. D. Khudyakova, V. N. Nikulin, O. R. Aslyamov, G. V. Khokhlova, A. V. Solovyova, A. A. Rodionov, A. V. Kryachkova, Yu. Yu. Shamurova, I. V. Tantsyreva, I. N. Baryshikova, M. G. Ataev, M. O. Radzhabov, M. M. Isakhanova, M. A. Umetov, L. V. Elgarova, I. A. Khakuasheva, E. I. Yamashkina, M. V. Esina, T. A. Kunyaeva, A. M. Nikitina, N. V. Savvina, Yu. E. Spiridonova, E. A. Naumova, B. M. Nazarov, A. A. Keskinov, V. S. Yudin, S. M. Yudin, A. V. Kontsevaya

“…The results obtained characterize the current situation and time trends of the last decade and contain important information on smoking epidemiology in Russia.…”
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Shengui Sansheng San alleviates the worsening of blood–brain barrier integrity resulted from delayed tPA administration through VIP/VIPR1 pathway by Jiacheng Hu, Yiyang Li, Xingping Quan, Yan Han, Jinfen Chen, Mengchen Yuan, Ying Chen, Manfei Zhou, Enze Yu, Jiahao Zhou, Dawei Wang, Ruibing Wang, Yonghua Zhao

“…Simultaneously, the permeability of BBB declined, with increased expressions of tight junction proteins ZO-1, and Occludin and proper BMECs tight junction morphology, and it suggested that VIP was released by neurons rather than astrocytes or BMECs. …”
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Rhizosphere domestication enhances root colonization and plant growth promotion performance of Bacillus velezensis SQR9 by Zhengqi Wang, Yike Zhao, Jiahui Shao, Jingjing Wang, Weibing Xun, Xinli Sun, Zhihui Xu, Youzhi Miao, Guidong Huang, Derui Liu, Derui Liu, Ruifu Zhang, Qirong Shen, Nan Zhang

“…The overuse of chemical fertilizers has caused severe soil degradation and environmental pollution, necessitating sustainable alternatives such as microbial fertilizers containing plant growth-promoting rhizobacteria (PGPR). …”
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Management and Operation Transformation of Urban Park Green Spaces from the Perspectives of Public Goods Provision and Fiscal Sustainability by Peiyi JIA

“…On the supply side, fiscal austerity and debt containment policies severely constrain traditional funding channels. …”
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A Study on the Possibility of Molecular Communication between Honey Bees and Sunflower through the Interspecies Transfer of Small RNAs by Leila Gharehdaghi, Gholamhosein Tahmasbi, Taher Harkinezhad

“…As we delve deeper into the extensive dimensions of this molecular relationship, it becomes increasingly clear that these interactions could serve as a roadmap for future breeding studies. …”
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Training Manual for Prevention of Covid-19 Disease among Hospital Personnel by Ali Poormohammadi, Ghasem Azarian

“…Also, at 5°C, the viral transmission is significantly increased. While at 30°C, the viral transmission between hosts is obviously decreased. …”
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