Cluster-randomized trial of the implementation of the Responses to Illness Severity Quantification (RISQ) system in children with acute malnutrition 6 to 59 months of age in Ngouri... by Nancy M. Dale, Youssouf Djidita Hagre, Susan Shepherd, George Tomlinson, Stanley Zlotkin, Masra Ngaradoum, Mahmat Bechir, Marius Madjissem, Charles Tehoua, Christopher Parshuram

“…The RISQ System is to be used as an adjunct to current care practice to aid clinicians in clinical decision-making. …”
Get full text

Be AIware! An AI Competency Model for K-12 Education by Lana Sattelmaier, Jan Pawlowski

“…Teachers, in particular, face increasing demands to respond to AI-driven transformations in learning environments yet lack structured guidance on which competencies matter. …”
Get full text

Preparation and Characterization of Activated Carbon Made from Robusta Coffee Skin (Coffea Canephora) by Raudhatul Raihan, Adi Setiawan, Lukman Hakim, Muhammad Muhammad, Muhammad Arif, Hadi Hosseiniamoli

“…Indonesia is one of the coffee-producing countries where production tends to increase from year to year. Currently, residuals from coffee-fruit processing such as coffee-skin and husks are thrown away without any use and this biomass residual contains several toxic chemicals such as alkaloids, tannins, and polyphenols. …”
Get full text

Impaired plasma membrane calcium ATPase activity and mitochondrial dysfunction contribute to calcium dysregulation in Fabry disease-related painful neuropathy by Francesco Formaggio, Asia Pizzi, Cecilia Delprete, Davide Pasqualini, Isabella Mataloni, Roberto Rimondini, Ludovica Campolongo, Vincenzo Donadio, Anna Maria Ghelli, Rocco Liguori, Marco Caprini

“…The obtained results suggest that other transport proteins participate in Ca2+ homeostasis in FD and their dysfunction may be directly involved in nociception. In this context, plasma-membrane Ca2+ ATPases exhibited reduced activity in FD, leading to an increased resting [Ca2+]i in sensory neurons. …”
Get full text

The impact of poverty reduction and development interventions on non-communicable diseases and their behavioural risk factors in low and lower-middle income countries: A systematic... by Jessie Pullar, Luke Allen, Nick Townsend, Julianne Williams, Charlie Foster, Nia Roberts, Mike Rayner, Bente Mikkelsen, Francesco Branca, Kremlin Wickramasinghe

“…However, studies investigating the impact of improved income on obesity tend to show an increased risk. Embedding NCD impact evaluation into development programmes is crucial in the context of the Sustainable Development Goals and the rapid epidemiological transitions facing LLMICs.…”
Get full text

Clinical Study of Safety and Efficacy of a Polymer-Subunit Adjuvant Influenza Vaccine Applied in Combination with an Immune Modulator in People Aged 60 and Over by V. V. Romanenko, I. V. Osipova, D. A. Lioznov, S. Yu. Martsevich, A. V. Ankudinova, T. V. Chebykina

“…There is evidence that the addition to the inactivated influenza vaccine immunomodulators immunogenicity of vaccines increased significantly. Goal. To evaluate the effectiveness of the vaccine Grippol® plus with immunomodulator Polyoxidonium® for elderly people aged 60 and older Materials and method. …”
Get full text

Polyphenols of Mulberry White (Morus alba L.) Leaves as a Source of Functional Food: A Review by Hagar F. Forsan, Menatalla R. Fayed, Noureldin M. Farahat, Walaa M. Gabr, Ezzeldeen M. Alswerky, Asmaa E. Abd El-Hak, Mohamed A. Fouda, Mennat-Allah Safwat

“…Mulberry leaves are economically feasible due to their historical importance in sericulture, so their production increases yearly, but the large output leads to a large percentage of residues. …”
Get full text

Antioxidative and Antimelanoma Effects of Various Tea Extracts via a Green Extraction Method by Yihui Chen, Jyun-Yin Huang, Yichi Lin, I-Fan Lin, Yi-Ru Lu, Li-Heng Liu, Hui-Min David Wang

“…Tea (Camellia sinensis) contains high level of antioxidant elements and is a well-known beverage consumed worldwide. …”
Get full text

Deep mutagenesis scanning using whole trimeric SARS-CoV-2 spike highlights the importance of NTD-RBD interactions in determining spike phenotype. by Ruthiran Kugathasan, Ksenia Sukhova, Maya Moshe, Paul Kellam, Wendy Barclay

“…New variants of SARS-CoV-2 are continually emerging with mutations in spike associated with increased transmissibility and immune escape. Phenotypic maps can inform the prediction of concerning mutations from genomic surveillance, however most of these maps currently derive from studies using monomeric RBD, while spike is trimeric, and contains additional domains. …”
Get full text

Ghrelin stimulation of growth hormone-releasing hormone neurons is direct in the arcuate nucleus. by Guillaume Osterstock, Pauline Escobar, Violeta Mitutsova, Laurie-Anne Gouty-Colomer, Pierre Fontanaud, François Molino, Jean-Alain Fehrentz, Danielle Carmignac, Jean Martinez, Nathalie C Guerineau, Iain C A F Robinson, Patrice Mollard, Pierre-François Méry

“…Indeed, ghrelin does not modify synaptic currents of GHRH neurons. However, ghrelin exerts a strong and direct depolarizing effect on GHRH neurons, which supports their increased firing rate.…”
Get full text

Disease progression & treatment need in sub-genotype C4 hepatitis B infection: a retrospective cohort study in the Northern Territory, Australia by Genevieve E. Martin, Kelly Hosking, Kelly Banz, Catherine Gargan, Geoff Stewart, Belinda Greenwood-Smith, Penelope Ramsay, Jaclyn Tate-Baker, Christine Connors, Paula Binks, Melita McKinnon, Prashanti Manchikanti, George Garambaka Gurruwiwi, Nicole Allard, Ashleigh Qama, Jessica Michaels, Emily Vintour-Cesar, Robert Batey, Catherine Marshall, Peter Nihill, Tammy-Allyn Fernandes, Karen Fuller, Steven Y. C. Tong, David Boettiger, Benjamin Cowie, Joshua S. Davis, Sarah Mariyalawuy Bukulatjpi, Jane Davies, on behalf of the Hep B PAST Partnership

“…Only 6·7% of untreated individuals were treatment eligible under current guidelines. Using the 2024 World Health Organisation guidelines, this increased to 50% due mostly to fibrosis and population prevalence of diabetes. …”
Get full text

Berberis lycium: A Miracle Medicinal Plant with Multifaceted Health Benefits by Bashir Ahmad, Abduh Murshed, Mohamed Y. Zaky, Imran Khan, Faiz ur Rahman, Magda H. Abdellattif, Guojun Liu, Jun Lu

“…The annual sale of medicinal plants increases over time. In plants, Berberis vulgaris f. lycium (Royle) Parsa (Berberis lycium), also called boxthoran barberry, Indian barberry, or Indian lyceum contains key alkaloids such as berberine, camptothecin, koumidine, salutaridine, luteanine, palmatine, and protopine. …”
Get full text

A Review of Reject Brine Disposal, Management, and Construction Applications by Pranita Banerjee, Essam K. Zaneldin, Ali H. Al-Marzouqi, Waleed K. Ahmed

“…Desalination is becoming crucial to meet the increasing global demand for potable water. Despite its benefits, desalination produces reject brine, a highly concentrated saline byproduct, which poses substantial environmental risks if not managed properly. …”
Get full text

The Middle East Shiite Arc: A Real Threat or Geopolitical Chimera? by A. V. Sarabiev

“…The term Shiite Crescent, or Shiite Arc, is becoming increasingly popular in political and academic discourse as well as in the media. …”
Get full text

Specific features of antagonism of <i>Bacillus</i> bacteria against toxinogenic <i>Fusarium</i> fungi in protecting plants against disease and contamination with mycotoxins (review... by T. M. Sidorova, A. M. Asaturova, V. V. Allakhverdyan

“…The role of lipopeptides produced by bacteria in inhibiting the growth of fungi, which manifests itself both through the destruction of the cell wall of the fungus and by increasing the immune status of the plant, has been shown. …”
Get full text

Editor’s Note by Alberto Raposo

“…This indicates that JIS is being increasingly recognized as an interesting publication vehicle. …”
Get full text

Sustainable Growth from a Factor Dependence and Technological Progress Perspective: A Case Study of East China by Ying Liu, Wan-Ming Chen, Sheng-Yuan Wang, Xiao-Lan Wu

“…The paper constructs an economic growth model that contains human, physical capital, innovation, and energy factors and estimates the output elasticity of seven provinces and cities in East China in the period of 2004–2018. …”
Get full text

National Museums and Their Societal Roles: A Case Study of Finland and Japan by Shikoh Shiraiwa

“…In this article I focuses on museum professionals in Finnish and Japanese national museums within the context of current social and cultural sustainability discourses, who face an increased responsibility to democratize museum narratives and acknowledge inconvenient histories and the ongoing coloniality of the institutions and repatriation of cultural insignia. …”
Get full text

IDEA: Image database for earthquake damage annotationZenodo by Ilaria Senaldi, Chiara Casarotti, Martina Mandirola, Alessio Cantoni

“…Such onthology, can be used either to expand the presented dataset or to produce new ones, in order to increase the availability of data annotated according to a common standard, from the structural engineering point of view. …”
Get full text

SOCIAL CONSTRUCTION OF TUBERCULOSIS by Andrei DOBRE

“…Despite the medical knowledge about the disease, analizing it from a sociological and anthropological point of view could generate a better understating of the disease, it’s social factors and the complexity of the context. Being the leading cause of death among the socio-professionally active population, with approximately 2 million deaths annually, prior to the establishment of certain control and surveillance measures, it is necessary to we understand the social factors and the costs of the disease, elements that increase the risk of infection / death, and what are the needs and services to be addressed. …”
Get full text