Novel Hypericin-loaded nanoparticles as a new drug delivery system ameliorate olanzapine-induced early renal injury and oxidative stress: In vitro and in vivo approaches by Abeer M. Abd El-Hameed, Fatimah A.R. AbdulAlim, Amal H. Alsehli, Fadwa A. Elroby

“…The HP-SiNPs release profile, entrapment efficiency, cytotoxicity against the Vero cell line, renal function parameters, antioxidant efficacy, and histological changes in male rats administered with OLZ were all investigated, and they were compared to those of free HP.XRD reveals the development of an HP-silica-based composite with a 275.0 nm particle size, which increases BET surface area and thermal stability. An entrapment efficiency of around 95.61 ± 0.28 %, and a prolonged release of less than 20 % after 12 h were validated by the current results. …”
Get full text

Exposure to secondhand smoke from cigarettes and secondhand aerosol from tobacco and nicotine products in indoor and outdoor public spaces in the European Union: a cross-sectional... by Anthony A Laverty, Ariadna Feliu, Filippos T Filippidis, Constantine I Vardavas, Cristina Martínez, Charis Girvalaki, Armando Peruga, Charlotte Xin Li, Pin-Chun Wang, Cornel Radu Loghin

“…Introduction In December 2024, the Council of the European Union (EU) adopted a recommendation to expand regulations on the use of nicotine-containing products both in indoor settings and specific outdoor areas. …”
Get full text

From waste to weapon: the potential of medicinal plant waste extracts for eco-friendly crop disease management by Chang-Jie Jiang, Yao Sun, Shijiao Xu, Shijiao Xu, Xinqiong Liu, Xianzhi Xie

“…The increasing challenge of managing crop diseases requires innovative and sustainable approaches. …”
Get full text

Transition Effects in Bridge Structures and Their Possible Reduction Using Recycled Materials by Mariusz Spyrowski, Krzysztof Adam Ostrowski, Kazimierz Furtak

“…This article serves as a review of the current challenges in bridge engineering, specifically addressing the transition effect and the utilization of recycled materials. …”
Get full text

Substance P- and Insulin-like Growth Factor 1-derived Tetrapeptides for Neurotrophic Keratopathy Related to Leprosy: A Clinical Trial by Shoko Kondo, MD, Yoshiko Okano, MD, PhD, Satoshi Iraha, MD, PhD, Shoji Tokunaga, PhD

“…Although leprosy is bacteriologically curable, there is currently no efficient treatment. Eye drops containing tetrapeptides, phenylalanine-glycine-leucine-methionine-amide (FGLM-NH2) and serine-serine-serine-arginine (SSSR), derived from substance P and insulin-like growth factor 1, are clinically efficacious in the treatment of corneal epithelial disorders caused by neurotrophic keratopathy. …”
Get full text

Teucrium polium induces apoptosis in peripheral blood lymphocytes isolated from human chronic lymphocytic leukemia by Zarić Milan, Živković-Zarić Radica, Mitrović Marina, Nikolić Ivana, Čanović Petar, Milosavljević Zoran, Jovanović Danijela, Zelen Ivanka

“…The activation of apoptosis is one of the main molecular mechanisms responsible for anti-cancer activities of most of the currently studied potential anti-cancer agents, including natural compounds. …”
Get full text

Comparative Study of Pectin and Kappa-Carrageenan-Based Films Loaded With Boswellic Acid and Acetyl-11-Keto-Beta-Boswellic Acid for Active Packaging by Yasir Abbas Shah, Saurabh Bhatia, Ahmed Al-Harrasi, Mohammad Tarahi, Talha Shireen Khan, Tanveer Alam, Esra Koca, Levent Yurdaer Aydemir

“…Moreover, the water contact angle measurements revealed that the films containing AKBA showed a noticeable increase in contact angles, reflecting an enhancement in hydrophobicity. …”
Get full text

Sustainable Machining Using Eco-Friendly Cutting Fluids: A Review by Pankaj Kumar, Amit Kumar Jain, Prem Kumar Chaurasiya, Damodar Tiwari, Anitha Gopalan, Joshuva Arockia Dhanraj, Jenoris Muthiya Solomon, Aravinth Sivakumar, Karthikeyan Velmurugan, Johannex Fefeh Rushman

“…The base fluids of eco-friendly cutting fluids should contain some vegetable oil. Due to their eco-friendly, thermal, and tribological qualities, these types of machining fluids are becoming increasingly popular among researchers throughout the world. …”
Get full text

An Integrated Profiling of Liver Metabolome and Transcriptome of Pigs Fed Diets with Different Starch Sources by Miao Yu, Zhenming Li, Yiyan Cui, Ting Rong, Zhimei Tian, Dun Deng, Zhichang Liu, Ruiyang Zhang, Xianyong Ma

“…However, current research on the effects of diets with different starch sources on animals at the extraintestinal level is still very limited. …”
Get full text

The rheology of the geological medium of interblock seismically active faults in the continental lithosphere: a key to understanding the generation of the strongest earthquakes in... by S. I. Sherman, E. A. Gorbunova

“…A decrease in the viscosity is facilitated by an increase in the fault length and leads to weakening of the geological medium and decreases its strength properties. …”
Get full text

OPTIMAL OPERATION OF ELECTRICAL POWER GENERATORS FOR OIL WELLS OPERATED BY ARTIFICIAL LIFTING AT RUMILA FIELD by Majid Abdulhameed Abdulhy Al-Ali, V. Yu. Kornilov, A. G. Gorodnov

“…Due to the remote locations for each of the ESPs the current strategy is to supply power to ESPs using individual diesel engine generators located at each remote ESP well site. …”
Get full text

The Influence of Alkali Cations on the Performance of Pt Electrodes in Kolbe Electrolysis of Acetic Acid by Talal Ashraf, Prof. Bastian Timo Mei, Prof. Guido Mul

“…Using rotating ring disc electrode measurements, we highlight the strong contribution of the oxygen evolution reaction particularly for electrolytes containing Li+ and Na+ which decreases the selectivity for Kolbe oxidation. …”
Get full text

Taurodeoxycholate Aggregation Explored by Molecular Dynamics: Primary-To-Secondary Micelle Transition and Formation of Mixed Micelles with Fatty Acids by Fatmegyul Mustan, Anela Ivanova, Slavka Tcholakova

“…The latter creates a very suitable medium for hosting hydrophobic molecules in the micelles containing unsaturated fatty acids.…”
Get full text

Comorbidity as a factor initiating a shift in the microelement composition of saliva by A. M. Imanov, Yu. A. Mazur, F. Ya. Gadzhiev, A. A. Skalny, Z. S. Khabadze, E. M. Kakabadze

“…The comorbidity of diseases reflects the mutual influence of pathological conditions of individual organs and systems of the body, which requires taking into account the current state of the patient. The presence of comorbidity in modern dentistry is one of the important problems that require attention in diagnosing a patient's condition, selecting treatment tactics and predicting the results of interventions. …”
Get full text

The story of elimination of visceral leishmaniasis (kala-azar) in India-Challenges towards sustainment. by Shyam Sundar

“…As a corollary benefit, there was a sharp decline in the incidence of VL due to the reduced prevalence of the vector to extremely low levels, resulting in substantial decreases in the number of KA cases. In the early 1970s, a surge in the number of cases was noted, and since then, it has taken the shape of the current epidemic. …”
Get full text

Dual contribution of ASIC1a channels in the spinal processing of pain information by deep projection neurons revealed by computational modeling. by Magda Chafaï, Ariane Delrocq, Perrine Inquimbert, Ludivine Pidoux, Kevin Delanoe, Maurizio Toft, Frederic Brau, Eric Lingueglia, Romain Veltz, Emmanuel Deval

“…All deep WDR-like neurons recorded from spinal slices exhibit an ASIC current with biophysical and pharmacological characteristics consistent with functional expression of ASIC1a homomeric channels. …”
Get full text

Scientific Opinion on Review of the European Union Summary Report on trends and sources of zoonoses, zoonotic agents and food‐borne outbreaks in 2009 and 2010 specifically for the... by EFSA Panel on Animal Health and Welfare (AHAW)

“…These results, however, are not linked to further interpretation e.g. the potential reasons for any decrease or increase. It was recommended that the AHAW and BIOHAZ Panels should be consulted (e.g. as part of their annual mandate) before the Report is released to the public.…”
Get full text

Impact of the COVID-19 pandemic on rural communities: a cross-sectional study in the Sichuan Province of China by Mohsin Shafi, Junrong Liu, Deng Jian, Imran Ur Rahman, Xunwei Chen

“…Notably, we find that local households are worried about their income losses regardless of their socioeconomic status (40%–43%), level of income (37%–43%) and industry involvement (38%–43%). However, as income increases, the level of stress decreases. The results further show that government transfer payment is a significant factor in reducing stress due to its reliable and uninterrupted income flow. …”
Get full text

Special features for functionalization of carbon nanotubes nanopowders by N. O. Oliinyk, G. D. Ilnytska, G. A. Bazaliy, I. M. Zaitseva, M. A. Marinich, O. M. Sizonenko, A. S. Torpakov

“…Mass share of impurities decreases 3.7 times, mass share of soluble impurities decreases 7 times, specific magnetic susceptibility increases 5.2 times, electrokinetic potential increases 7.8 times. …”
Get full text

<i>MAGE-C1</i> gene and mage-c1 protein expression comparison in primary multiple myeloma patients by E. A. Makunina, L. P. Mendeleeva, V. L. Surin, M. V. Soloviev, M. V. Firsova, A. M. Kovrigina, A. A. Sherstnev, I. V. Gal’tseva, Y. O. Davydova, S. M. Kulikov

“…Single factor analysis showed that patients with decreased MAGE-C1 gene and mage-c1 protein expression levels achieved a significantly higher antitumor response to bortezomib-containing regimens, while high expression was accompanied by refractoriness to bortezomib.…”
Get full text