Chemical characterization and cytotoxic effect of three edible fungi (Morchella) against breast cancer cells: A therapeutic approach

“…Current breast cancer therapeutics are associated with short-term efficacy, increased drug resistance, and severe adverse reactions, thus demanding the development of new therapeutic approaches. …”
Get full text

Towards Non-Animal Testing in European Regulatory Toxicology: An Introduction to the REACH Framework and Challenges in Implementing the 3Rs by Katerina Stoykova

“…REACH permits animal testing as a last resort only and imposes the 3Rs principle (Replacement, Reduction, and Refinement of animal testing). Nevertheless, the current regulatory practices still heavily rely on animal-based methods. …”
Get full text

BUILDING ENVIRONMENTAL AWARENESS AMONG STUDENTS IN POLAND – CASE STUDY WROCŁAW UNIVERSITY OF SCIENCE AND TECHNOLOGY by Magdalena WĘGLARZ

“…Generation Z, current university students, has demonstrated a notable increase in environmentally conscious actions and attitudes. …”
Get full text

Mind the semantic gap: semantic efficiency in human computer interfaces by James Horsley

“…Current ML systems have fundamental semantic gaps in bespoke human context, real-time world knowledge, and how those relate to HCI tooling. …”
Get full text

COVID-19 Vaccines in the Pediatric Population: A Focus on Cardiac Patients by Ghena Lababidi, Hossam Lababidi, Fadi Bitar, Mariam Arabi

“…This review also contains current and future perspectives, as well as a section on the cardiovascular implications and related dynamics of pediatric COVID-19 vaccination.…”
Get full text

Demilitarized Status in International Law and the Militarization Problem of the Eastern Aegean Islands by Cüneyt Yüksel, Nesrin Singil

“…As such, Greece engages in activities and actions aimed at violating the demilitarized status of the Eastern Aegean Islands, with these violations observed to have begun increasing. For this reason, Greece’s claims should be evaluated in the context of current issues, and considering the steps Türkiye will take in response to these violations is also essential. …”
Get full text

ANALYSIS OF MODELS OF EARLY DEBT REPAYMENT IN THE Generalized CREDIT TRANSACTIONS by Y. E. Kasimov, A. N. Kolesnikov

“…So in the uniform schemes of repayment of consumer credit each payment contains the same part of principal amounts and the total interest. …”
Get full text

Impact of Photovoltaic Penetration on the Distribution System Operation. Case Study Albania by Andi Hida, Olsi Karapici, Rajmonda Buhaljoti, Diamant Gashi

“…The increase in photovoltaic penetration, especially in the low voltage distribution system, requires the necessity to identify the problems it causes, as well as the benefits it provides. …”
Get full text

I tweet, therefore I am: a systematic review on social media use and disorders of the social brain by Nancy Yang, Bernard Crespi

“…In each case, the virtual nature of social media facilitates the delusionality because the self is defined and bolstered in this highly mentalistic environment, where real-life exposure of the delusion can be largely avoided. Current evidence also suggests that increased social media usage, via its disembodied and isolative nature, may be associated with psychotic spectrum phenotypes, especially delusionality, by the decoupling of inter and intra-corporeal cues integral to shared reality testing, leading to the blurring of self-other boundaries.…”
Get full text

METABOLIC REPROGRAMMING OF MICROGLIA AND ASTROCYTES AS A FACTOR IN THE REGULATION OF NEUROINFLAMMATION IN ISCHEMIC STROKE by Mikhail Bobrov, Vadim Nikitin, Marina Burak

“…This review presents current ideas about metabolic reprogramming in astrocytes and microglial cells in the context of pathophysiological processes in cerebral ischemia.…”
Get full text

Pre-industrial and future shifts in seasonal precipitation climatology for large river basins across the continental U.S.A by Kyungmin Sung, James H Stagge

“…These trends are projected to continue on their current trajectory through the end of the century. …”
Get full text

The Impact of Deforestation and Restoration Trends on Land Use and Land Cover Changes in Eastern Mau Forest Reserve, Kenya by Mike Passiany, Kyalo Kiema John Bosco

“… Context and Background This study aims to assess the environmental impact of Land Use and Land Cover (LULC) changes in the Eastern Mau Forest Reserve, Kenya, using remote sensing and GIS techniques. …”
Get full text

Quality improvement project to improve cardiovascular risk screening in patients with rheumatoid arthritis by Mireille Edens, Monique Hoekstra, Harriet de Vries, Clarinda van den Bosch-Schreuder

“…The CV risk screening in the Netherlands is performed by the general practitioner (GP).Purpose The aim of our project was to increase the CV risk screening of patients with RA, performed by the GP, from 46% to 65% of the selected patients of 40 years and older, within the time frame of our project (18 months).Context The project was carried out at the outpatient rheumatology clinic at Isala Zwolle, a large teaching hospital, in an area with 106 GP practices. …”
Get full text

Debris flows dynamic risk assessment and interpretable Shapley method-based driving mechanisms exploring – A case study of the upper reach of the Min River by Yufeng He, Mingtao Ding, Yu Duan, Hao Zheng, Wen He, Jun Liu

“…The study found that the areas with extremely high debris flow risk decreased by 18.57%, while the areas with moderate and high risk levels increased by 8% and 14% respectively. With this trend of overall risk increasing, the population and buildings affected by extremely high debris flow risk have increased by 20% and 30% respectively. …”
Get full text

Data-Driven Proactive Early Warning of Grid Congestion Probability Based on Multiple Time Scales by Haobo Fu, Ruizhuo Wang, Bingxu Zhai, Yuanzhuo Li, Pengyuan Li, Rui Zhang, Haoyuan He, Siyang Liao

“…With the development of new power systems, the increased interactive demand on the load side, and the high proportion of renewable energy sources on the power side, grid congestion problems due to increased system uncertainty are becoming more frequent. …”
Get full text

Process Parameter Study on New Electrochemical Chloride Extraction of Corroded Concrete in Marine Environment by HE Lang

“…Experimental results showed that the ECE efficiency increased with the increase of current density, and the optimal current density was 2 A/m2 after overall consideration. …”
Get full text

Renegotiating Social Citizenship - Democracy in Welfare Service States by Arne Wohlfarth

“…This article illustrates the importance of social services in the context of current social investment strategies. It outlines a program of new challenges, pitfalls and opportunities for the effective realization of welfare citizenship in a service-based welfare architecture by contextualizing sui-generis characteristics of social services in the area of tension between democratic demands and current forms of welfare architecture and provision. …”
Get full text

Association of plasma levels of Sestrin2 with adiposity and metabolic function indices in healthy and diabetic subjects from Qatar Biobank by Muhammad Ammar Zahid, Shahenda Salah Abdelsalam, Hicham Raïq, Hanan H. Abunada, Aijaz Parray, Abdelali Agouni

“…Conversely, in the diabetic cohort, higher Sestrin2 levels were paradoxically linked to increased triglycerides (OR: 1.57), the product of triglyceride glucose and waist circumference (OR: 1.8), body fat (OR: 1.72), waist circumference (OR: 1.82), waist-to-hip ratio (OR: 1.96) and metabolic syndrome (OR: 1.48).ConclusionsThese findings suggest that Sestrin2 may play a complex and context-dependent role in metabolic regulation, potentially serving as a protective factor in healthy individuals but contributing to metabolic dysfunction in the context of established diabetes. …”
Get full text

Enhancing malaria elimination in high-transmission settings: the synergy of concurrent vector control and chemotherapy by Ronald Mulebeke, Adoke Yeka, Jean-Pierre van Geertruyden

“…Thus, tailoring strategies to the specific local context and transmission dynamics is essential for maximizing impact. …”
Get full text

Public-private partnership in the field of cybersecurity by S.V. Sieriebriak

“…Thus, the article not only summarizes the current state of development of public-private partnerships in Ukraine, but also identifies priorities for its improvement, especially in the field of cybersecurity, which is a key component of national security in the face of current challenges. …”
Get full text