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301
Evaluation of the Antistaphylococcal Activity of the Pyrimidine Derivative
Published 2023-09-01“…The development of safe and effective drugs with antimicrobial activity is currently a priority task of modern pharmacology. The need to obtain new antimicrobial agents is associated with the presence of problems, the main of which is the development of polyresistance of the pathogenic pathogen to existing antibacterial drugs. …”
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302
The Role of Hydrogen Sulfide in the Regulation of the Pulmonary Vasculature in Health and Disease
Published 2025-03-01“…This review sets out what is currently known about the mechanisms by which H<sub>2</sub>S and related sulfur species exert their actions on pulmonary vascular tone, both acutely and chronically, and discusses the potential of sulfide-releasing drugs as treatments for the different types of PH which arise in humans.…”
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303
Hair loss: The role of nutritional support in a comprehensive approach to hair loss treatment
Published 2025-01-01“…The therapy exhibited significant clinical efficacy, evidenced by a decrease in hair loss, a reduction in the number of hairs in the telogen phase, and an increase in hair growth density per square centimeter as observed in the control phototrichogram. …”
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304
Arginine–NO pathway modulated energy metabolism in the hepatopancreas and muscle of female Litopenaeus vannamei
Published 2025-03-01“…Dietary arginine increased muscle crude protein content, decreased hepatopancreas crude protein content and activated the target of rapamycin 1 pathway. …”
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305
Effects of Conditioning Temperature on Pellet Quality, Nutrients Digestibility, and Metabolizable Energy of Broilers Diet
Published 2024-12-01“…So that the amount of electricity usage decreased (quadratic, p< 0.001), and increased pellet PDI (quadratic, p<0.001) and pellet hardness (linear, p<0.002) by increasing in conditioning temperature. …”
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306
Study on Vertical Uplift Resistance Characteristics of Pre-Drilled Planted Piles in Boulder Strata
Published 2025-03-01“…The results indicate that the ultimate uplift bearing capacity of piles with boulders in the pile body is approximately twice that of piles without boulders, and this difference decreases with the increase of the distance between boulder and the pile end; under ultimate uplift loading, the pile end of a pile containing boulders contributes approximately 32% of the uplift bearing capacity, whereas the pile end without boulders contributes almost no uplift capacity; the presence of boulders increases the cross-sectional diameter of the pile, providing additional vertical support from the overlying soil, thereby significantly enhancing the ultimate uplift bearing capacity of the pile. …”
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307
Effects of temporary erosion control blanket and grass cover on the rates of runoff and sediment in the cut and fill slopes of forest roads using a rainfall simulation test
Published 2024-07-01“…The use of erosion control blankets is a soil bio-engineering method that can effectively reduce runoff and sediment and increase slope stability. Therefore, the current research aimed to temporarily stabilize soil using protective covering treatments, such as jute, straw, wood chips, Festuca grass cover, and nano zeolite super absorbent, to reduce the amount of runoff and sediment. …”
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308
Evaluation of the efficacy and safety of cytoflavin as a neuroprotector based on a systematic review
Published 2025-03-01“…There is a tendency towards rejuvenation and an increase in morbidity. Drug therapy aimed at neuroprotection and improving the restoration of neurological functions according to clinical recommendations includes a succinate-containing drug – Cytoflavin. …”
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309
Optical Identification of Plasmodium falciparum Malarial Byproduct for Parasite Density Estimation
Published 2019-01-01“…Empirical computation of ratio of the ODs for the blood absorption bands revealed reduction in the ODs with increasing PD. Multispectral images containing uninfected red blood cells (u-RBCs) and P. falciparum‐infected red blood cells (i-RBCs) on unstained blood smear slides exhibited spectrally determined decrease in both reflected and scattered pixel intensities and increase in transmitted pixel intensities with increasing PD. …”
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310
Microbiological Characteristics of Intestinal Biocenosis of Ambulator Patients Having Behavioral Risk Factors for Chronic Non-Communicable Diseases
Published 2021-05-01“…When using a metaprebiotic complex containing inulin and oligofructose, an improvement in the composition of the intestinal microflora was found due to a decrease in the frequency of release of conditionally pathogenic enterobacteria and other gram-negative microorganisms (median degree of contamination: from 0.45 (0.3-0.98) to 0.3(0.21-0.7) at low suboptimal status and from 0.5(0.7-1.7) to 0.31 (0.2-1.3) at high) and increase the frequency of enterococcal excretion (median degree of contamination: from 5,58 (4,16-7,0) tо 6,3 (4,8-7,8) at low suboptimal status and from от 4,5 (2,8-6,3) tо 5,1 (3,8-6,4) at high). …”
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311
Insight into influence of degradation metabolism of Firmicutes on the microstructure of anthracite coal
Published 2025-01-01“…Also, the relative abundance of a number of key metabolic enzyme genes capable of catalyzing the oxygen-containing functional groups into the structure of the coal molecule and the de-cyclization reaction were increased. …”
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312
STAT2/SLC27A3/PINK1-Mediated Mitophagy Remodeling Lipid Metabolism Contributes to Pazopanib Resistance in Clear Cell Renal Cell Carcinoma
Published 2024-01-01“…While tyrosine kinase inhibitors (TKIs) are currently the first-line treatments for advanced/metastatic ccRCC, patients often develop resistance after TKI therapy. …”
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313
Experimental study on tensile performance of horizontal joint bolted connections in fully assembled modular construction reinforced concrete
Published 2025-01-01“…According to the calculation theory for punching shear failure bearing capacity, the reduced peak load-bearing capacity of Mode III compared to Mode II was attributed to the reduction in the effective height of the punching shear cone caused by the crushing zone, consequently resulting in decreased anti-punching shear capacity. In Mode IV, when the load was increased to 134.2 kN, abrupt fracture failure of the concrete at the cross-section above the operating hand-hole of the specimen was observed, with limited cracking. …”
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314
Study of structural and mechanical properties of suppositories with bifonazole
Published 2025-03-01“…They indicate the existence of a present structure in the suppository composition, that is evidenced by the decrease in effective viscosity simultaneously with the increase in deformation forces. …”
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315
Analyzing the effects of a Maxwell nanofluid with graphene oxide on rectangular, triangular, and chamfered baffles on the surface of a stretched surface
Published 2025-05-01“…The results of this paper examine how to achieve optimal results through the use of design of experiments (DOE) and response surface methodology (RSM).It highlights that rising magnetic pressure currents and the development of magnetic vortices significantly decrease the nanofluid’s temperature and flow velocity. …”
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316
CFD Simulation of Hydrodynamic Properties of Perforated Triangular Corrugated Plate Filler Under Reduced Pressure
Published 2025-06-01“…As the perforation aperture increases, the flow rate decreases overall and the low flow rate area increases. …”
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317
Impact of frailty in older people on health care demand: simulation modelling of population dynamics to inform service planning
Published 2024-10-01“…Prescriptions increased with increasing age in both Fit and Mild frailty categories but decreased in moderate and severe categories. …”
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318
HIGH VOLUME BRICK POWDER CONCRETE SYNERGISTIC WITH METAKAOLIN: PHYSICOMECHANICAL PROPERTIES AND DRYING SHRINKAGE
Published 2025-02-01“…The workability of the mixes containing 10%MK:40%BP and 20%MK:30%BP has slightly decreased, while the mechanical properties were increased and the drying shrinkage were declined. …”
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319
Post-pandemic patient safety: have the characteristics of incidents with harm changed? Comparative observational study in primary care via review of medical records with a trigger...
Published 2024-11-01“…Conclusions No differences were found in the avoidability, severity, place of occurrence, or contributory factors of PSIHs before the pandemic and currently. In terms of the nature of these incidents, the outcomes revealed an increase in diagnostic errors (excluding diagnostic tests), which could be attributed to a greater frequency of remote consultations and a decrease in the longitudinality of care resulting from the shortage of professionals.…”
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320
Effects of Metamorphic Degree of Coal on Coal Dust Wettability and Dust-Suppression Efficiency via Spraying
Published 2020-01-01“…According to the experimental results of coal’s microproperties, with the improvement of metamorphic degree, the content of hydrophilic oxygen-containing functional groups on the surface, the surface roughness, the specific surface area, and the interpore diameter all decreased. …”
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