Amyloidogenic immunoglobulin light chains disturb contractile function and calcium transients in a human cardiac spheroid model of light chain (AL) amyloidosis by Mélanie Bézard, Jean-Sébastien Vartanian-Grimaldi, Julien Henri, Denisa Calin, Amira Zaroui, Mounira Kharoubi, Thibaud Damy, Onnik Agbulut, Ekaterini Kordeli

“…LC-treated hiPSC-CM cultures and LC-containing spheroids presented structural and functional defects including: (1) decreased levels and subcellular disorganization of sarcomeric protein alpha-actinin; (2) abnormal accumulation of calcium handling SERCA2a protein; (3) impaired contractility of spheroids and altered calcium transients. …”
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Evaluating Dietary Red Lentil Screenings on Performance, Antioxidant Status, Caecal Environment, and Intestinal Morphometric Features in Rabbits by Gianluca Pugliese, Caterina Losacco, Letizia Passantino, Giovanni Lentini, Maria M. Cavalluzzi, Michele Schiavitto, Simona Tarricone, Vito Laudadio, Vincenzo Tufarelli

“…Dietary RLS significantly decreased serum total cholesterol, LDL, and HDL, along with an enhancement of the overall serum antioxidant capacity. …”
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Two decades of cropland monitoring in Changsha-Zhuzhou-Xiangtan city group: trends and future predictions by Wenbo Zhang, Dazhao Fan, Song Ji, Yang Dong, Dongzi Li, Ming Li

“…Rapid urbanization currently poses a threat to cropland areas. Therefore, exploring the pattern of change in cropland areas and its driving mechanism is of great significance in safeguarding regional economic development and food security. …”
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Identification, Evolution and Expression Analyses of the Hox Family in Procambarus clarkii by Xiaoyu WEI, Qian HU, Zemao GU, Yanhe LI

“…Homeobox genes are ubiquitous in eukaryotic genomes and can be transcribed into a homeodomain of approximately 60 amino acids. Hox genes are currently the most studied class of homeobox genes. …”
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“It’s supposed to be real meat” – An analysis of media coverage of the first United States sales approval of cell-cultivated chicken by Alejandra Sofia Marquez, Ellen Messer, Suzannah Gerber, Sean B. Cash

“…The findings in this study can be utilized by industry stakeholders, policymakers, and academics to determine what information is currently being communicated to consumers through the media and how this information might be influencing consumers’ perceptions of cell-cultivated meat.…”
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Features of Paradigm for forming anti-cataclysmic instruments for preventing aggressive interstate conflicts – artificial intelligence (AI) in terms of ensuring objective personnel... by B. M. Andrushkiv, L. S. Golovkova, N. B. Kyrych, O. B. Pohajdak, K. Hannouf

“…The article shows that in the context of the Ukrainian military economy, one of the main factors of efficiency of defence work, production and social development is the managerial tools and high-quality personnel which currently being formed in the sectoral and territorial areas, as well as humanism and scientific validity of managerial decisions in the field of interstate partnership relations. …”
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Global, Regional, and National Burden of Nonrheumatic Valvular Heart Disease and Its Attributable Risk Factors in 204 Countries and Territories, 1990 to 2019: Results From the Glob... by Le Li, Limin Liu, Zhicheng Hu, Likun Zhou, Zhuxin Zhang, Lingmin Wu, Ligang Ding, Zhao Hu, Lihui Zheng, Yan Yao

“…Background Nonrheumatic valvular heart disease (NRVD) is increasingly becoming a significant public health concern, particularly among older people. …”
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Teucrium polium induces apoptosis in peripheral blood lymphocytes isolated from human chronic lymphocytic leukemia by Zarić Milan, Živković-Zarić Radica, Mitrović Marina, Nikolić Ivana, Čanović Petar, Milosavljević Zoran, Jovanović Danijela, Zelen Ivanka

“…The activation of apoptosis is one of the main molecular mechanisms responsible for anti-cancer activities of most of the currently studied potential anti-cancer agents, including natural compounds. …”
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SETup automotive: a Method for Systems Engineering Transformation in automotive industry by Iris Graessler, Benedikt Grewe

“…With this in mind, systems engineering (SE) is currently being introduced on a large scale into the automotive industry. …”
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Exploring the Role of EU Subsidies in Enhancing the Competitiveness of Slovak Farms by Ivana Kravčáková Vozárová, Rastislav Kotulič

“…The competitiveness of Slovak farms is currently strongly influenced not only by internal factors such as productivity, innovation, and management, but also by external factors, especially political and economic decisions at the EU level. …”
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Learner Engagement in Using Kahoot! within a University English Proficiency Course by Mohd Zulfadli Mat Husin, Ruhil Amal Azmuddin

“…Background/purpose – Game-based learning is becoming increasingly popular among educators in higher institutions. …”
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A Study on Macroeconomic Variables’ Effect on Unemployment across Europe by Flavius Ilie Radac, Vasile Paul Bresfelean, Cristina Roxana Tănăsescu

“…Due to the economic crisis of 2008, there was a significant increase in unemployment rates in several European countries, with notable impacts in some countries like Romania, Greece, Portugal, Spain, and Italy. …”
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Detecting and Responding to a Dengue Outbreak: Evaluation of Existing Strategies in Country Outbreak Response Planning by Julia Harrington, Axel Kroeger, Silvia Runge-Ranzinger, Tim O'Dempsey

“…Dengue outbreaks are occurring with increasing frequency and intensity. Evidence-based epidemic preparedness and effective response are now a matter of urgency. …”
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Anatomic and mechanical considerations in restoring volume of the face with use of hyaluronic acid fillers with a novel layered technique by Mohan K Thomas, James A Dsilva, Ateesh J Borole, Sudhir M Naik, Soma G Sarkar

“…Context: Facial fillers have revolutionized the field of cosmetic facial rejuvenation as it has become the prime sought - after rejuvenation procedure offering youthful, 3-dimensional look with minimal invasiveness. …”
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Counterfactual choice and learning in a neural network centered on human lateral frontopolar cortex. by Erie D Boorman, Timothy E Behrens, Matthew F Rushworth

“…Although the neural system responsible for tracking the value of choices actually taken is increasingly well understood, whether a neural system tracks counterfactual information is currently unclear. …”
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Self-sufficiency in the healthcare workforce: a system dynamics model of the domestic and foreign educated nursing and midwifery workforce in Ireland by Terence Hynes, Paul Caulfield, Peter O’Connor, John Cullinan

“…Ireland, the context for this study, currently relies heavily on foreign educated nurses and midwives to meet its demand, with Government policy moving towards a domestic recruitment model. …”
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Demographic responses of hybridizing cinquefoils to changing climate in the Colorado Rocky Mountains by Kelly A. Carscadden, Daniel F. Doak, Meagan F. Oldfather, Nancy C. Emery

“…Our findings demonstrate that hybrids in this system are neither intrinsically unfit nor universally more vigorous than parents, suggesting that the demographic consequences of hybridization are context‐dependent. Our results also imply that shifts to warmer and drier conditions could have particularly negative repercussions for P. pulcherrima, which is currently the most abundant taxon in the study area, possibly as a legacy of more favorable historical climates. …”
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Is South Africa ready for point-of-care, non-sputum tests for TB diagnosis? An assessment of end-user perceptions on a novel urine test and tongue swab for TB testing by Nasiphi Mqedlana-Ntombela, Vanessa Fargnoli, Salome Charalambous, Kavindhran Velen, Sonjelle Shilton, Violet Chihota

“…Novel non-sputum sample types currently under development can increase TB testing, however there is limited knowledge on end-user perceptions on these tests. …”
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Are interventions for environmentally sustainable dietary behaviours effective? A review by Y Ran, U M Persson, T Lindahl, M Jonell, A Brons, B Macura, J Candel, A Abu Hatab, E Röös

“…In the face of growing environmental pressures, understanding how governance can promote more sustainable dietary behaviours is increasingly critical. However, a synthesis of available intervention strategies for behavioural change is currently missing. …”
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The Association Between Traumatic Brain Injury and the Risk of Cognitive Decline: An Umbrella Systematic Review and Meta-Analysis by Ioannis Mavroudis, Dimitrios Kazis, Foivos Efstratios Petridis, Ioana-Miruna Balmus, Vasileios Papaliagkas, Alin Ciobica

“…Background: There is currently increasing interest in the implication of traumatic brain injury (TBI) as a potential risk factor for long-term neurodegenerative conditions, such as dementia and Alzheimer’s disease (AD). …”
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