CHAC1: a master regulator of oxidative stress and ferroptosis in human diseases and cancers by Jiasen Sun, Hui Ren, Jiawen Wang, Xiang Xiao, Lin Zhu, Yanyan Wang, Lili Yang

“…CHAC1, an essential regulator of oxidative stress and ferroptosis, is increasingly recognized for its significant roles in these cellular processes and its impact on various human diseases and cancers. …”
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Unit-level Digital Twin Model Construction Technology for Part Manufacturing Processes by LI Dong, LIN Zhiwen, CHEN Chuanhai, ZHAO Yongsheng, LIU Zhifeng

“…This paper reviews the construction technology of unit-level digital twins for part machining, focusing on three key aspects: virtual entity model construction, process strategy design, and process parameter decision making. The current research status and limitations of these aspects in both domestic and international contexts are discussed. …”
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Optimal management of crop pests in the presence of agritourism by Badriya Al Hinaai, Ibtisam Al Abri, Abdullah M. Al-Sadi, Slim Zekri, Kelly Grogan

“…The findings indicate that while pest management is crucial for reducing fruit damage and increasing yields, current practices fail to maximize economic returns. …”
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Ashwagandha and Its Role in Stress Reduction, Hormonal Balance, and Athletic Recovery: An Evidence-Based Review by Weronika Ossowska, Maksymilian Czarnota, Wiktoria Ösztreicher

“…State of Knowledge: Current clinical studies suggest that ashwagandha may effectively lower cortisol levels, thereby supporting stress resilience in both mentally and physically demanding contexts. …”
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Urban green infrastructure and social cohesion in Lagos Metropolis, Nigeria by Adedotun Dipeolu, Amos Taiwo, Temitope Adebara

“…Urbanisation has increasingly resulted in social fragmentation, insecurity, and health challenges in cities worldwide. …”
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OPTIMIZATION OF IMID-BASED THERAPIES by Murat Çınarsoy

“…In this case, it is clear that multiple myeloma treatment optimization cannot be achieved by considering multiple myeloma treatment only as applying the appropriate drug combination.In order to ensure the optimization of IMID-based therapies, it is necessary to take a broad perspective.This perspective should include the correct selection of the patient to be treated with IMID, the development and implementation of IMID forms that will increase patient compliance, the use of techniques to predict the development of resistance, side effect management during treatment, preventing the increase in disease burden with appropriate maneuvers by following the disease burden after treatment, and drug-free follow-up.It is recommended to avoid thalidomide in the presence of peripheral neuropathy, to prefer other agents instead of lenalidomide in the presence of renal function loss, and to avoid pomalidomide in patients with COPD.Nex-20, a once-monthly subcutaneous formulation of lenalidomide, is expected to be an important breakthrough in improving patient compliance.Prediction of which patients will develop resistance will be very useful in order to have the best treatment outcomes.Calculation of miRNA risk scores, measurement of lenalidomide metabolite levels in urine, measurement of cereblon levels in blood, or immunohistochemical detection of cereblon levels are some of the methods currently being tried to predict disease resistance.Patients who develop anemia should be treated with erythropoietin, skin reactions should be treated with steroids and antihistamines, diarrhea should be treated with loperamide and colestyramine, and in general, the drug should be discontinued and the same dose or a lower dose should be insisted upon.An important part of treatment is maintenance therapy with lenalidomide. …”
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Justification of military neutrality of the Republic of Serbia at a time of erosion of neutrality in Europe by Kajtez Ilija, Starčević Srđan

“…The first chapter briefly describes the historical decline of neutrality during the first half of the 20th century. In that context, observation made in mid last century, according to which neutrality was becoming an obsolete concept, is true. …”
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Effects of β-glucan on the performance and gut integrity of broilers under acute heat stress conditions by Mohannad Abuajamieh, Mohmmad Al-Qaisi, Zeinab M.H. Mahasneh, Rahaf Istatieh, Mohamed A. Abedal-Majed, Anas Abdelqader, Abdur-Rahman Al-Fataftah

“…The treatments were: 1) a basal diet (Ctrl); 2) a diet containing 1 g/kg of β-glucan (BG1); 3) a diet containing 2 g/kg of β-glucan (BG2); 4) a diet containing 3 g/kg of β-glucan (BG3). …”
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Robust prediction of tool-tissue interaction force using ISSA-optimized BP neural networks in robotic surgery by Yong-Li Yan, Teng Ren, Li Ding, Tiansheng Sun, Shandeng Huang

“…The novel method has the potential to increase surgical safety, accuracy and efficiency, representing an advance in the field of surgical robotics.…”
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THE ETHICAL STARTUP? by Alexis Walker

“…Instead, the view proposed here would ask companies to do more to prevent or decrease the risk of a breach of privacy, unexpected later use of data, and reidentification. …”
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Analysis of Herd Behavior in Industry Groups of the Tehran Stock Exchange by Yahya Ebrahimpour, Elham Nobahar, Parviz Mohamadzadeh

“…Over the past decade, the TSE has undergone significant growth, marked by a dramatic increase in the number of active trading codes and a sharp rise in their trading values, underscoring the necessity of examining herd behavior in this context. …”
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Knowledge of and misconceptions about the spread and prevention of HIV infection among older urban women attending the Tshwane District Hospital, South Africa by W. Rauf, S. Hitchcock, A. Rauf, P.J. Becker

“…Background: Statistics around the world show a rapid increase in HIV infection in the older population. …”
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Examining Stromal Cell Interactions in an In Vitro Blood–Brain Barrier Model with Human Umbilical Vein Endothelial Cells by Andrea Margari, Simon Konig, Vignesh Jayarajan, Silvia Rizzato, Giuseppe Maruccio, Emad Moeendarbary

“…Understanding the function of the blood–brain barrier (BBB) in health and disease, as well as improving drug delivery across the BBB, remains a critical priority in neuroscience research. However, current in vitro models of the BBB have become increasingly complex and challenging to implement. …”
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Electrocoagulation for Cattle Slaughterhouse Wastewater Management: A Review of Technologies and Treatment Parameters by Iip Sugiharta, Agung Abadi Kiswandono, Kamisah Delilawati Pandiangan, Wasinton Simanjuntak

“…This review examines key operational parameters of EC, including current density, pH, electrode type, and contact time, while comparing its performance with electro-oxidation (EO) and coagulation-flocculation (CF). …”
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Fatty acid analysis identifies an aberrant circulating triglyceride composition in patients with hypertriglyceridemia-induced acute pancreatitis by Alicia Leikin-Frenkel, Margarita Mayorov, Tamar Luvish, Aviv Shaish, Hofit Cohen, Yehuda Kamari, Dror Harats, Mudi Misgav, Rom Keshet

“…We found that TGs of hypertriglyceridemic patients with current HIAP contain increased levels of oleic acid, linoleic acid, and the trans FA elaidic acid, all potentially toxic to pancreatic cells; and decreased levels of the pancreatic-protective FAs gondoic acid and docosahexaenoic acid. …”
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Metal flow behavior and energy consumption model during the extrusion process of a 6063 aluminum alloy profile with complex cross-section by Dewei Zhang, Haijie Xu, Sheng Xu, Fei Tong, Kai Chen, Zixuan Li, Jinrong Zuo, Xuedao Shu

“…The simulation results show that the standard deviation of metal flow velocity (representing the forming quality) was decreased as container temperature decreases, and the extrusion speed, billet temperature and die temperature increase. …”
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Effectiveness of laughter therapy with healthcare clowns on the mood of hospitalised adults by Yelsyn Mauricio Porras-Jiménez, Carmen Álvarez-Nieto, Karen Lizeth Romero-Granados, César Augusto Pinzón-Ordoñez, Isabel María López-Medina

“…Discussion: Current evidence supports laughter therapy with healthcare clowns as a tool to foster positive emotions, reduce negative psychological symptoms, and improve emotional well-being in various contexts, highlighting the importance of collaborative implementation with medical staff to strengthen well-being in healthcare settings. …”
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A systems approach to sustainable finance: Actors, influence mechanisms, and potentially virtuous cycles of sustainability by Beatrice Crona, Garry Peterson, Megan Meacham, Giorgio Parlato, Steven J. Lade, Juan C. Rocha, Victor Galaz

“…Summary: Over the past decade, corporate investors have increasingly recognized that responsible environmental and social practices are essential to long-term financial success. …”
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Early mental health intervention and supported self-care for LGBTQ+ young people in the UK: a mixed-methods study by Elizabeth McDermott, Rachael Eastham, Elizabeth Hughes, Emily Pattison, Katherine Johnson, Stephanie Davis, Steven Pryjmachuk, Ceu Mateus, Olu Jenzen, Felix McNulty

“…Stage 2: service mapping This stage of the study investigated and mapped current LGBTQ+ youth-specific mental health service provision across the UK. …”
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A Method of the Vibration Information Detection for Rotating Machinery Based on the Rolling-Shutter CMOS and Digital Image Processing by Yonggong Yuan, Ji Zhang, Nanwangdi Li, Haifeng Wang, Yuxin Hu, Yilong Wang, Ning Mei, Han Yuan

“…The study investigates non-contact vibration information acquisition and fault diagnosis methods. …”
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