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3461
Nuclear pore dysfunction and disease: a complex opportunity
Published 2024-12-01“…In this review, we summarize the current understanding of nuclear pore biology in physiological and pathological contexts and discuss potential therapeutic approaches for addressing nuclear pore injury and dysfunctional nucleocytoplasmic transport.…”
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3462
Kalirin, a Key Player in Synapse Formation, Is Implicated in Human Diseases
Published 2012-01-01“…In cultured hippocampal/cortical neurons, overexpression of Kalirin-7 increases spine density and spine size whereas reduction of endogenous Kalirin-7 expression decreases synapse number, and spine density. In Kalirin-7 knockout mice, spine length, synapse number, and postsynaptic density (PSD) size are decreased in hippocampal CA1 pyramidal neurons; these morphological alterations are accompanied by a deficiency in long-term potentiation (LTP) and a decreased spontaneous excitatory postsynaptic current (sEPSC) frequency. …”
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3463
Re-use of Building Products in the Netherlands
Published 2019-01-01“…This research departs from the desire to understand the practice of reuse of building products from a systemic standpoint, to illuminate its current condition and help to foresee future perspectives. …”
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3464
Development and biomechanical evaluation of a 3D printed analogue of the human lumbar spine
Published 2025-01-01“…Moreover, there are increasing ethical concerns with human dissection practices. …”
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3465
Building a Robust Scenario Library for Safety Assurance of Automated Driving Systems: A Review
Published 2025-01-01“…While every region has its specificities, certain contexts pose particular difficulties in scenario development. …”
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3466
Recent research progress on metal ions and metal-based nanomaterials in tumor therapy
Published 2025-02-01“…In addition, tumor recurrence and metastasis are also difficult problems faced in clinical treatment. In this context, the importance of metal-based nanomaterials in tumor therapy is increasingly highlighted. …”
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3467
The Ecological Restoration Strategies in Terrestrial Ecosystems Were Reviewed: A New Trend Based on Soil Microbiomics
Published 2025-03-01“…This review aims to address the ecological crises currently experienced by diverse terrestrial ecosystems and to provide a comprehensive overview of the specific practices of soil microorganisms in the context of ecological restoration. …”
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3468
Simulation Study on the Open-Circuit Voltage of Amorphous Silicon p-i-n Solar Cells Using AMPS-1D
Published 2014-04-01“…The simulated result of illuminated current density-voltage characteristics was in a good agreement with experimental values. …”
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3469
Archéologie et nouvelles technologies appliquées à l’étude des dynamiques contemporaines de destruction du patrimoine culturel : le cas du pillage en Méso-Amérique
Published 2024-10-01“…Archaeology is increasingly delving into the study of recent phenomena, seeking to understand current social practices to address contemporary societal challenges. …”
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3470
A Study of Observed Climate Change Effects on Grapevine Suitability in Oltenia (Romania)
Published 2025-05-01“…Viticulture represents an important agricultural sector in Oltenia, which is one of the Romanian regions most affected by temperature increases. The main purpose of the present study was to analyze the changes in climate suitability for grapevine and wine production against this climate context in the region. …”
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3471
Paradigm shift: outcomes from a physician-scientist undergraduate pathway program
Published 2025-02-01“…Results Since its establishment in 2014, PARAdiGM is already increasing entry of URiM students into the physician-scientist pathway. …”
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3472
SOME ASPECTS OF ADMINISTRATIVE-LEGAL REGULATION OF ACTIVITY OF EXECUTIVE POWER BODIES IN THE DIGITAL REALITY
Published 2021-09-01“…As you know, the development of the information society is currently associated with the implementation of projects for the development of the digital economy. …”
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3473
“It’s supposed to be real meat” – An analysis of media coverage of the first United States sales approval of cell-cultivated chicken
Published 2025-06-01“…The findings in this study can be utilized by industry stakeholders, policymakers, and academics to determine what information is currently being communicated to consumers through the media and how this information might be influencing consumers’ perceptions of cell-cultivated meat.…”
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3474
SETup automotive: a Method for Systems Engineering Transformation in automotive industry
Published 2025-01-01“…With this in mind, systems engineering (SE) is currently being introduced on a large scale into the automotive industry. …”
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3475
Exploring the Role of EU Subsidies in Enhancing the Competitiveness of Slovak Farms
Published 2025-03-01“…The competitiveness of Slovak farms is currently strongly influenced not only by internal factors such as productivity, innovation, and management, but also by external factors, especially political and economic decisions at the EU level. …”
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3476
Learner Engagement in Using Kahoot! within a University English Proficiency Course
Published 2022-06-01“…Background/purpose – Game-based learning is becoming increasingly popular among educators in higher institutions. …”
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3477
A Study on Macroeconomic Variables’ Effect on Unemployment across Europe
Published 2024-06-01“…Due to the economic crisis of 2008, there was a significant increase in unemployment rates in several European countries, with notable impacts in some countries like Romania, Greece, Portugal, Spain, and Italy. …”
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3478
Detecting and Responding to a Dengue Outbreak: Evaluation of Existing Strategies in Country Outbreak Response Planning
Published 2013-01-01“…Dengue outbreaks are occurring with increasing frequency and intensity. Evidence-based epidemic preparedness and effective response are now a matter of urgency. …”
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3479
Anatomic and mechanical considerations in restoring volume of the face with use of hyaluronic acid fillers with a novel layered technique
Published 2014-01-01“…Context: Facial fillers have revolutionized the field of cosmetic facial rejuvenation as it has become the prime sought - after rejuvenation procedure offering youthful, 3-dimensional look with minimal invasiveness. …”
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3480
From Radicalism to Conformism: Post-Soviet Ideological Trajectory of Russian Communist Party in 1993–2022
Published 2025-07-01“…Currently, the Communist Party is going through a contradiction between radical rhetoric and conformist practice. …”
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