Reducing Plasmodium falciparum malaria transmission in Africa: a model-based evaluation of intervention strategies. by Jamie T Griffin, T Deirdre Hollingsworth, Lucy C Okell, Thomas S Churcher, Michael White, Wes Hinsley, Teun Bousema, Chris J Drakeley, Neil M Ferguson, María-Gloria Basáñez, Azra C Ghani

“…However, it remains unclear what overall reduction in transmission is achievable using currently available tools.<h4>Methods and findings</h4>We developed an individual-based simulation model for Plasmodium falciparum transmission in an African context incorporating the three major vector species (Anopheles gambiae s.s., An. arabiensis, and An. funestus) with parameters obtained by fitting to parasite prevalence data from 34 transmission settings across Africa. …”
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CO2 methanation over low-loaded Ni-M, Ru-M (M = Co, Mn) catalysts supported on CeO2 and SiC by Chopendra G. Wasnik, Maki Nakamura, Taiki Shimada, Hiroshi Machida, Koyo Norinaga

“…An efficient circulation and utilization of CO2 is critical in the current environmental context. Methanation, an exothermic process, emerges as a critical strategy for effective CO2 utilization. …”
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Analysis of production and financial potential as a basis for developing a strategy for modernizing the Russian economy by Ljudmila I. Rozanova, Sergei V. Tishkov

“…This goal predetermines the solution of such problems as analysis of the current state of the production base, assessment of financial resources for the production upgrade, identification of opportunities and risks in the implementation of modernization processes. …”
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MECHANISMS FOR ENSURING THE ECONOMIC DEVELOPMENT OF RURAL AREAS THROUGH THE FORMATION OF THEIR ENERGY DEPENDENCE BASED ON THE INTENSIFICATION OF BIOFUEL PRODUCTION by Yuliia Okhota, Denys Titov, Svitlana Dotsiuk

“…To achieve this goal, the article discusses the theoretical aspects of energy independence, analyzes current practices of biofuel production, and provides recommendations for their further implementation. …”
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Towards a sustainable rare disease and orphan drug ecosystem in Saudi Arabia: policy insights from a multi-stakeholder workshop by Ghada Mohammed Abozaid, Ghada Mohammed Abozaid, Hussain Abdulrahman Al-Omar, Abdulaziz Alrabiah, Asma AlMuaither, Amy Jayne McKnight

“…Through a series of presentations, educational sessions, and plenary discussions, participants examined the current landscape of RDs in SA, identified barriers to accessing ODs, and recommended strategies and initiatives to improve the accessibility, innovation, and sustainability of ODs.ResultsThe workshop highlighted key challenges recognized by a diverse group of 59 participants, including the absence of a national strategy, absent of local RDs and ODs definitions in the Saudi context, limited awareness and understanding of RDs among healthcare professionals, delayed diagnoses, scarcity of treatment and diagnosis centers for RDs, insufficient screening and prevention programs, regulatory hurdles in approving and importing ODs, and financial constraints. …”
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Understanding Device Integrations Within Diabetes Apps: Mixed Methods Analysis of App Features and User Reviews by Jessica Turner, Katarzyna Stawarz

“…First, we aimed to understand the current landscape of device integrations within diabetes apps and how well they meet users’ needs. …”
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New radar altimetry datasets of Greenland and Antarctic surface elevation, 1991–2012 by M. R. Suryawanshi, M. R. Suryawanshi, M. McMillan, J. Maddalena, F. Piras, J. Aublanc, J.-A. Daguzé, C. Grau, Q. Huang

“…To reliably constrain multi-decadal trends in ice sheet imbalance, and to place current observations within a longer-term context, requires continued efforts to optimise the processing of data acquired by the older historical missions and to evaluate the accuracy of these measurements. …”
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Propagation Characteristics of Multi-Cluster Hydraulic Fracturing in Shale Reservoirs with Natural Fractures by Lianzhi Yang, Xinyue Wang, Tong Niu

“…Understanding the effects of reservoir and fracturing conditions on fracture propagation is of great significance for optimizing the hydraulic fracturing process and has not been adequately explored in the current literature. In the context of shale reservoirs in Yibin, Sichuan Province, China, the study selects outcrops to prepare samples for uniaxial compression and Brazilian splitting tests. …”
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Significant fundamental translational research on breast cancer in China: progress and prospects by LU Yufeng, WANG Han, XIE Yifan, JIANG Yizhou, SHAO Zhimin

“…Breast cancer is the most prevalent malignant tumor that poses a threat to women's health in China, with incidence and mortality rates persistently increasing. Given this critical situation, there is an urgent need to optimize therapeutic options through basic translational research to address current treatment challenges. …”
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Adaptation Potential of Teachers of the Third Age in the Conditions of Higher Education Transformation by E. A. Shuklina, M. V. Pevnaya, E. A. Shirokova

“…In many countries around the world, the increase in life expectancy leads to significant social transformations. …”
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‘It was a joint plan we worked out together’. How the I-WOTCH programme enabled people with chronic non-malignant pain to taper their opioids: a process evaluation by Martin Underwood, Kate Seers, Charles Abraham, Harbinder Kaur Sandhu, Vivien P Nichols, Sam Eldabe, Alleyne Sharisse, Balasubramanian Shyam, Betteley Lauren, Booth Katie, Carnes Dawn, D Furlan Andrea, Haywood Kirstie, Iglesias Urrutia C Paola, Lall Ranjit, Manca Andrea, Mistry Dipesh, Noyes Jennifer, Rahman Anisur, Shaw Jane, KY Tang Nicole, Taylor Stephanie, Tysall Colin, Underwood Martin, J Withers Emma

“…It provided people with a forum in which to learn about the current thinking about opioid usage and its effects. …”
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Multi-century mean summer temperature variations in the Southern Rhaetian Alps reconstructed from <i>Larix decidua</i> blue intensity data by R. Cerrato, M. C. Salvatore, M. C. Salvatore, M. Brunetti, A. Somma, C. Baroni, C. Baroni

“…<p>Ongoing climate change is likely to cause a worldwide temperature increase of 1.5 °C by the mid-century. To contextualize these changes in a long-term context, historical climatological data extending beyond data obtained from instrumental records are needed. …”
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Patient-Generated Collections for Organizing Electronic Health Record Data to Elevate Personal Meaning, Improve Actionability, and Support Patient–Health Care Provider Communicatio... by Drashko Nakikj, David Kreda, Karan Luthria, Nils Gehlenborg

“…However, augmenting them with patient-generated data, which are entered with flexible richness and structure, could add context, elevate meaning, and improve actionability. …”
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Access to veterinary care in Canada: a cross-sectional survey of animal healthcare organizations and interventions by Quinn Rausch, Maryam Alhamdan, Shane Bateman, Michelle Evason, Valli Fraser-Celin, Courtney Graham, Jamie Saad, Michelle Tuma, Karen Ward, Lauren Van Patter

“…IntroductionMany Canadians struggle to access healthcare for their animals, but little data is available from the Canadian context on how barriers to care are being addressed, and with what effects.MethodsThe aim of this research was to characterize service providing organizations, barrier mitigation tools, community partnerships, and evaluation metrics used by organizations attempting to increase access to animal healthcare in Canada. …”
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‘Communities are attempting to tackle the crisis’: a scoping review on community plans to prevent and reduce opioid-related harms by Carol Strike, Michael Parkinson, Nimitha Paul, Sue Keller-Olaman, Susan Massarella, Jayne Caldwell, Greg Penney, Rita Henderson

“…Stakeholders identified three key implications to our findings: addressing equity and stigma-related barriers towards people with lived experience of substance use; improving data collection to facilitate evaluation; and enhancing community partnerships by involving people with lived experience of substance use.Conclusion Current understanding of the implementation and context of community opioid-related plans demonstrates a need for evaluation to advance the evidence base. …”
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Model of complex rehabilitation for patients with a simple form of schizophrenia by V. V. Chuhunov, V. O. Kurylo, V. L. Pidlubnyi, S. M. Kanyhina

“…The key to solving this problem is a multidisciplinary approach, within which it becomes possible to select congruent rehabilitation and psychoeducational techniques, taking into account the clinical and psychopathological content of this nosological form. In this context endogenous procedural mental disorders deserve special attention, as they are characterized by the highest level of social and labor maladjustment. …”
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Application of urinary peptide-biomarkers in trauma patients as a predictive tool for prognostic assessment, treatment and intervention timing by Gökmen Aktas, Felix Keller, Justyna Siwy, Agnieszka Latosinska, Harald Mischak, Jorge Mayor, Jan Clausen, Michaela Wilhelmi, Vesta Brauckmann, Stephan Sehmisch, Tarek Omar Pacha

“…Preemptive personalized treatment aimed at preventing these events is a crucial objective of patient management; however, the currently available scoring systems provide only moderate guidance. …”
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Use of filtration and electricity analogy in simulation of underflooding protection in urban construction by V. I. Sologaev

“…The methodology for complex calculation and modelling of the joint processes of water filtration in soils, the flow of electric current and electroosmotic filtration can find useful application in the development of effective protection against underflooding in urban construction. a sequence of algorithmic modelling steps is recommended. initially, it is recommended to run rough spreadsheet simulations on personal computers and mobile phones. next, a different modelling approach should be applied. based on the initial rough models of the previous step, it is necessary to write the algorithms in the programming language. the compiled model of the investigated filtration and electroosmosis processes will significantly increase the reliability of the design of protection against underflooding.conclusion. a comparison is made of the joint use of construction dewatering means of different physical essence, with simultaneous processes of gravitational filtration of underground water and passing a direct electric current through the drained soil, which causes an additional effect of electroosmosis. it is proposed to apply in a new way the analogy of water filtration and electric current in order to achieve more effective results of engineering activities by modeling protection against underflooding of building areas, ensuring the safety of urban construction when the level of groundwater rises.…”
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Can Unilateral Strength Training Optimize Change of Direction Mechanics and Mitigate Anterior Cruciate Ligament Injury Risk in Female Soccer Players? A Preliminary Pre–Post Interve... by Alice Rogalski, Ayrton Moiroux-Sahraoui, Maria Stergiou, Maxence Pieulhet, Maurice Douryang, Florian Forelli

“…Our findings suggest that individualized training interventions can influence current injury prevention strategies.…”
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DEVELOPMENT OF AUTOMATED EXCITATION AUXILIARY CUTTING SIMILAR EXPERIMENT PROTOTYPE AND ITS MECHANICAL EXPERIMENT by LU JinNan, YUE JianGuang, XIE Miao, WANG PengFei

“…The experimental results show that during the same time period, when there is active excitation, the initial time for increasing contact force is 0.07 s earlier than when there is no excitation, longer duration, contact force is reduced by 0.12 kN compared with no excitation, after excitation, the average cutting current decreased by 1.12 A.Through the test bench based on Similarity theory, the active excitation vibration experiment and test can be carried out on the cutting arm of the road-header under limited laboratory conditions. …”
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