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3241
Hydrogen Loss on Venus Driven by Photochemistry
Published 2025-01-01“…Venus has experienced substantial H loss through hydrodynamic outflow in its early history, transforming from a warm and wet state to the current arid and scorching state. While Venus continues to lose H today, no consensus has been reached regarding the present dominant escape mechanisms. …”
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3242
Contribution of the TRPM4 Channel to Osteogenic Differentiation of Human Aortic Valve Interstitial Cells
Published 2025-04-01“…Mineralization and osteogenic markers (bone morphogenetic protein 2, runt‐related transcription factor 2) were decreased when pro‐calcifying media contained 9‐phenanthrol or small hairpin RNA–TRPM4. …”
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3243
Justificación del valor educativo de la Educación Física y el docente. ¿Qué profesional del deporte debe impartir la materia de Educación Física? ¿El Maestro/a y Profesor/a de Educ...
Published 2020-07-01“…This theoretical review aims at explaining and reflecting on what quality Physical Education and teachers’ professional competencies are, so as not to confuse it with school sports. Currently, there are several institutions that recommend a Quality Physical Education, and among other aspects they emphasize that this should increase up to 3 hours per week both in the stage of compulsory primary and secondary education. …”
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3244
Effects of intercropping with legume forage on the rhizosphere microbial community structure of tea plants
Published 2024-11-01“…ContextIntercropping in agriculture is crucial for addressing challenges in intensive tea farming. …”
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3245
Empowering older adults in medication safety
Published 2025-12-01“…The semi-structured questions were open ended and based on patient empowerment models and previous research assessing videos to increase knowledge and promote behavior change. Focus groups were recorded and transcribed verbatim. …”
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3246
Assessment of The Potential Interference and Conflict of Artificial Intelligence With Human Rights and Citizenship: Challenges and Solutions
Published 2025-03-01“…However, it should not be forgotten that no matter how advanced AI becomes, it must adhere to certain limitations in its personhood status, similar to legal entities. In the context of the legal status of artificial intelligence in Iran, there are currently no definitive regulations. …”
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3247
Bifidobacterium animalis ssp. lactis BX-245-fermented milk alleviates tumor burden in mice with colorectal cancer
Published 2025-02-01“…Collectively, our data suggest that administering probiotic fermented milk containing specific functional strains such as BX245 could result in a reduction in tumor burden in CRC mice. …”
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3248
Improving outcomes for people with autism spectrum disorders by reducing mental health problems: the IAMHealth research programme including one RCT
Published 2025-05-01“…Factors contributing to this included beliefs about the causes of MHP and increased vulnerability with the context of a diagnosis of autism, knowledge of self-management and, based on prior experiences, a view that professional support or intervention was unavailable or inadequate. …”
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3249
Effects of ibrutinib and venetoclax on the expression of immune checkpoint molecules in leukemic blasts of patients with acute lymphoblastic leukemia
Published 2025-06-01“…By elucidating the precise underlying mechanisms, these drugs could emerge as promising therapeutic options, particularly in the context of combination therapy for ALL.…”
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3250
A novel therapeutic approach targeting PD-L1 in HNSCC and bone marrow-derived mesenchymal stem cells hampers pro-metastatic features in vitro: perspectives for blocking tumor-strom...
Published 2025-02-01“…Abstract Background Current conventional treatment regimens for head and neck squamous cell carcinoma (HNSCC), are poorly effective because of the emergence of resistance mechanisms. …”
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3251
Tuberculosis mortality and drug resistance among patients under TB treatment before and during COVID-19 in Burundi: a case–control study
Published 2025-05-01“…Conclusion TB mortality increased during the COVID-19 pandemic, particularly among MDR-TB patients. …”
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3252
MODERN APPROACHES TO DIAGNOSTICS AND TREATMENT OF DENTAL TRAUMA
Published 2020-12-01“…The current approach to the treatment of dental trauma is focused on less invasive and more biologically oriented methods of treatment of hard dental tissues, pulp, periodontal ligament and alveolar bone. …”
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3253
Advances and applications of empirical mode decomposition and its variants in hydrology: A review
Published 2025-02-01“…Empirical Mode Decomposition (EMD) has garnered increasing attention due to its ability to analyze non-linear and non-stationary data. …”
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3254
Effects of coix seed polyphenol extract on rumen fermentation, milk production, fatty acid profile, antioxidant activity, and polyphenol content in dairy goats
Published 2025-03-01“…Overall, the appropriate supplemental level of CSE was 1.5 g/kg in dairy goats under the conditions of the current experiment.…”
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3255
Organising general practice for care homes: a multi-method study
Published 2025-04-01“…Applying standardised costs to our data suggests that increasing contacts over time may increase primary care costs by up to £35,000 per annum for an average care home. …”
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3256
STAT2/SLC27A3/PINK1-Mediated Mitophagy Remodeling Lipid Metabolism Contributes to Pazopanib Resistance in Clear Cell Renal Cell Carcinoma
Published 2024-01-01“…While tyrosine kinase inhibitors (TKIs) are currently the first-line treatments for advanced/metastatic ccRCC, patients often develop resistance after TKI therapy. …”
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3257
Advancing the therapeutic effectiveness of paclitaxel in chronic lymphocytic leukemia through the simultaneous inhibition of NOTCH1 and SF3B1
Published 2025-03-01“…Overexpression of the splicing factor 3b subunit 1 (SF3B1) and neurogenic locus notch homolog protein 1 (NOTCH1) factors is typically found in chronic lymphocytic leukemia (CLL), leading to the development of chemotherapy resistance. Objective The current investigation aims to evaluate the chemosensitivity of CLL cells by blocking NOTCH1 and SF3B1 using chitosan lactate (CL) nanoparticles (NPs). …”
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3258
Immunological and physiological changes of exercise-released lactate on tumors: an important and new research window
Published 2024-12-01“…In the cancer immune cycle, the immune checkpoint PD-1 and its ligand PD-L1 collaborate to facilitate immune escape and promote tumor progression (Keir et al., 2008). In this context, a study revealed that lactate can enhance the expression of PD-L1 on tumor cells, suggesting that lactate may have a protective effect against tumors by increasing PD-L1 expression (Feng et al., 2017). …”
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3259
Presentation of Financial Assets in Russian Macroeconomic Statistics
Published 2021-10-01“…The purpose of the study. Currently, much attention is paid to the collection, presentation and analysis of data on the volume, structure and dynamics of economic assets. …”
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3260
Materials and Structures Used in Aeronautics: Present and Future Perspectives
Published 2024-12-01“…Trial and error can be costly in this context, necessitating well-planned design and engineering to ensure resistance to aerodynamic forces during flight. …”
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