Impaired plasma membrane calcium ATPase activity and mitochondrial dysfunction contribute to calcium dysregulation in Fabry disease-related painful neuropathy by Francesco Formaggio, Asia Pizzi, Cecilia Delprete, Davide Pasqualini, Isabella Mataloni, Roberto Rimondini, Ludovica Campolongo, Vincenzo Donadio, Anna Maria Ghelli, Rocco Liguori, Marco Caprini

“…The obtained results suggest that other transport proteins participate in Ca2+ homeostasis in FD and their dysfunction may be directly involved in nociception. In this context, plasma-membrane Ca2+ ATPases exhibited reduced activity in FD, leading to an increased resting [Ca2+]i in sensory neurons. …”
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Understanding data and information needs for palliative cancer care to inform digital health intervention development in Nigeria, Uganda and Zimbabwe: protocol for a multicountry q... by Richard Harding, Bassey Ebenso, Adlight Dandadzi, Eve Namisango, Kehinde Okunade, Kennedy Bashan Nkhoma, Omolola Salako, David Akeju, Olaitan Soyannwo, Elizabeth Namukwaya, Elizabeth Nabirye, Lovemore Mupaza, Emmanuel Luyirika, Henry Ddungu, Z Mike Chirenje, Michael I Bennett, Matthew J Allsop

“…However, there is currently a lack of any theoretical underpinning or data to understand stakeholder drivers for digital health components in this context. …”
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Monitoring individual rice field flooding dynamics over a large scale to improve mosquito surveillance and control by Mauricianot Randriamihaja, Tokiniaina M. Randrianjatovo, Michelle V. Evans, Felana A. Ihantamalala, Vincent Herbreteau, Christophe Révillion, Eric Delaitre, Thibault Catry, Andres Garchitorena

“…There is, therefore, increasing interest in the use of larval source management (LSM) to supplement current insecticide-based interventions. …”
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Research on Outdoor Thermal Comfort Strategies for Residential Blocks in Hot-Summer and Cold-Winter Areas, Taking Wuhan as an Example by Yongkuan Li, Yuchen Zeng, Wenyu Tu, Guang Ao, Guiyuan Li

“…With the intensification of climate challenges driven by rapid urbanization, the microclimate and thermal comfort of residential blocks have attracted increasing attention. Current research predominantly focuses on isolated morphological factors—such as building orientation, layout patterns, and height-to-width ratios—while neglecting the synergistic effects of multifactorial spatial configurations on outdoor thermal comfort. …”
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A whole process resilience management practice in coastal engineering by Yingtao Zhou, Yingtao Zhou, Yingtao Zhou, Chenhui Jiang, Yuanshu Jiang, Yu Zhu, Yu Zhu, Yu Zhu, Yan Jin, Xian Wang, Xi Feng, Weibing Feng

“…Coastal zones are crucial for protecting land from marine disasters, but they are increasingly threatened by erosion caused by storms and rising sea levels. …”
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The Bioethics-CSR Divide by Caio Caesar Dib

“…This includes investments, entrepreneurship models, and its relationship to stakeholders, leading to an increasing operationalization and globalization of the concept.[6] At first sight, these two movements seem to stem from different contexts. …”
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Fostering global primary care research: a capacity-building approach by Amanda Howe, Felicity Goodyear-Smith, Michael Kidd, Sherina Mohd Sidik, Chris van Weel, David Ponka, Megan Coffman, Krystle Elizabeth Fraser-Barclay, Richard D W Fortier, Robert P Lennon, Jeremiah K A Madaki, Bob Mash, Kristina Zawaly

“…Our aim is to explore the current risks or barriers to primary care research capacity building, identify the ongoing tensions that need to be resolved and offer some solutions, focusing on emerging contexts. …”
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Interculturalizing ELT: Culture-based classes to enhance language skills and intercultural communicative competence dimensions by Khalid Hicham, Naji Masned AlQbailat, Islam Asim Ismail, Nizar M. Qpilat, Nisreen Naji Al-Khawaldeh, Othman Khalid Al-Shboul, Fatima Zahra Masrar

“…This study aimed to analyze the impact of culture-based classes on ICC dimensions and language skills learning, examine English teachers' instructional strategies regarding culture and interculturality, and explore whether current pedagogy caters to ICC dimensions and language skills among EFL undergraduate learners. …”
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Neonates at Risk: Understanding the Impact of High-Risk Pregnancies on Neonatal Health by Rozeta Sokou, Alexandra Lianou, Maria Lampridou, Polytimi Panagiotounakou, Georgios Kafalidis, Styliani Paliatsiou, Paraskevi Volaki, Andreas G. Tsantes, Theodora Boutsikou, Zoi Iliodromiti, Nicoletta Iacovidou

“…High-risk pregnancies (HRPs) constitute a significant global health issue due to their strong association with increased maternal and neonatal morbidity and mortality. …”
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Development and characterization of amaranth protein-based edible films incorporating Satureja khuzestanica essential oil by Elahe Khalili, Gholamreza Jahed Khaniki, Saeedeh Shojaee-Aliabadi, Nabi Shariatifar, Ramin Aslani, Leila Mirmoghtadaie

“…The current research aimed to investigate the physicochemical and antimicrobial characteristics of the edible film based on amaranth protein containing Satureja khuzestanica essential oil. …”
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BK channel activity in skin fibroblasts from patients with neurological disorder by Ria L. Dinsdale, Thomas R. Middendorf, Deborah Disilvestre, David Adams, William Gahl, Ellen F. Macnamara, Lynne Wolfe, Camilo Toro, Cynthia J. Tifft, Andrea L. Meredith

“…Fibroblasts from the individual harboring the E656A variant showed decreases in the number of BK channels detected and E656A-containing transcripts compared to controls. …”
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Research Progress on Catalytic Conversion of Lignin to Chemicals by Xuezhi ZENG, Wenyu WANG, Minxian HUO, Yi QI, Xueqing QIU, Xuliang LIN, Yanlin QIN

“…Currently, lignin is primarily used for combustion to generate process heat. …”
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CONFRONTATION AND MUTUAL REFLECTION OF TWO WORLDS IN “THE GRASS DANCER” BY SUSAN POWER by Oksana G. Shostak

“…We have a desire to separate the indigenous tradition from the broad American, in particular, Anglo-American and recognize Indian writing as a component of the multicultural paradigm. Currently, there is a noticeable confrontation between two camps of literary critics: one of them is oriented to European literary theories and believes that they should form the basis of literary interpretations of indigenous writers’ works; another wing is determined by the need to clarify the peculiarities of the literary paradigm of “Indian realism” in the context of a globalized society taking into account new literary models of the perception of ethnic minorities. …”
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A Model of Human Resource Management System Suitable for the New Generation Z in Executive Organizations with Thematic Analysis Approach by Moein Pourahmadi, Saeed Jafarinia, Yusuf Vakili, Akbar Hasanpour

“…Without an appropriate organizational context for the activities and actions of Generation Z, human resource management programs are doomed to fail. …”
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The course and outcomes of COVID-19 in patients with ANCA-associated systemic vasculitis, receiving biological therapy (Rituximab, Mepolizumab): The results of the first 8 months o... by T. V. Beketova, V. V. Babak, M. D. Suprun

“…Objective. Currently, the issues of the effect of anti-B cell therapy or inhibitor of interleukin 5 on the risk of COVID-19 infecting and outcomes in patients with ANCA-associated vasculitis (AAV) has not been completely studied. …”
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Stochastic simulation modeling of the economics of providing additional living space for housed dairy cows by Jake S. Thompson, Chris D. Hudson, Jon N. Huxley, Jasmeet Kaler, Martin J. Green

“…Under the circumstances and contexts investigated, the results suggest that building for increased living space would be cost-effective. …”
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Interpersonal counselling for adolescent depression delivered by youth mental health workers without core professional training: the ICALM feasibility RCT by Jon Wilson, Viktoria Cestaro, Eirini Charami-Roupa, Timothy Clarke, Aoife Dunne, Brioney Gee, Sharon Jarrett, Thando Katangwe-Chigamba, Andrew Laphan, Susie McIvor, Richard Meiser-Stedman, Jamie Murdoch, Thomas Rhodes, Carys Seeley, Lee Shepstone, David Turner, Paul Wilkinson

“…However, alterations to the referral pathways did not increase the number of referrals made to the study. …”
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Long-term dynamics of forests with Pinus sibirica in the upper reaches of the River Kolva (Northern Pre-Urals, Russia) from 1938 to 2023 by Alexei A. Aleinikov, Vadim E. Aleksutin, Foma K. Vozmitel, Alexey N. Gunya

“…Due to the exceptionally slow regeneration following fires and logging activities, Pinus sibirica is absent in the forests formed over the studied period. The current federal legal restrictions prove ineffective as they target the preservation of forest stands containing over 30% of Pinus sibirica, while the majority of forests in the study area contain less proportion of this species. …”
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Development of a clinical decision support tool for Primary care Management of lower Urinary tract Symptoms in men: the PriMUS study by Adrian Edwards, Ridhi Agarwal, Janine Bates, Alison Bray, Sarah Milosevic, Emma Thomas-Jones, Michael Drinnan, Marcus Drake, Peter Michell, Bethan Pell, Haroon Ahmed, Natalie Joseph-Williams, Kerenza Hood, Yemisi Takwoingi, Chris Harding

“…General practitioners currently have no easily available assessment tools to diagnose lower urinary tract symptom causes. …”
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Extended Reality Interventions for Health and Procedural Anxiety: Panoramic Meta-Analysis Based on Overviews of Reviews by Tom Arthur, GJ Melendez-Torres, David Harris, Sophie Robinson, Mark Wilson, Sam Vine

“… BackgroundExtended reality (XR) technologies are increasingly being used to reduce health and procedural anxieties. …”
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