Research progress on novel nanomaterials mediated treatment of candidal keratitis by ZHAO Tianqi, LIU Lian

“…The incidence of Candida keratitis has been rising annually due to factors such as the misuse of immunosuppressive drugs and increased contact lens wear. Following infection, Candida itself and the formation of biofilms contribute to enhanced resistance against currently used systemic antifungal agents, including voriconazole, amphotericin B, itraconazole, and fluconazole,posing significant challenges to clinical treatment.Recently, research on nanomaterials-mediated drug delivery systems for treating Candida keratitis has burgeoned. …”
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Prescription of a THC/CBD-Based Medication to Patients with Dementia: A Pilot Study in Geneva by Barbara Broers, Zacharie Patà, Aline Mina, James Wampfler, Christian de Saussure, Sophie Pautex

“… Background: Dementia is increasing worldwide. No effective medication is currently available for the treatment of the underlying disease and accompanying behavioral symptoms. …”
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Study on surface deformation induced by shield excavation due to coarse particle content in strongly weathered rock layers. by Puzhen An, Baoxin Jia, Qinglei Yuan, Lei Chen

“…The results show that as the coarse particle content increases, the force transmission mechanism in the strongly weathered rock shifts from compressive deformation typical of fine-grained soils to point-contact force transmission between coarse particles. …”
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Chemotactic migration of T cells towards dendritic cells promotes the detection of rare antigens. by Renske M A Vroomans, Athanasius F M Marée, Rob J de Boer, Joost B Beltman

“…Although it has been shown that dendritic cells (DCs) carrying cognate antigen in some circumstances attract T cells chemotactically, it is currently still unclear whether chemoattraction of T cells towards DCs helps or hampers scanning. …”
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The Profile of Multidrug Tuberculosis Regimen and Treatment Outcomes in Pulmonary MDR-TB Patients at the Tertiary Referral Hospital Dr. Soetomo, East Java, Indonesia: A Seven-Year... by Muhamad Frendy Setyawan, Ni Made Mertaniasih, Soedarsono Soedarsono

“…The treatment outcome profile of MDR-TB patients shows the average percentage of cured (15%), died (12%), lost-to-follow-up cases (27%), moved to an individualized regimen or a different health facility (42%), and currently in the evaluation stage (4%). Overall from January 2017 to July  2022, the number of LTFU cases decreased (42, 46, 29, 19, 8, 4)%. …”
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ANALYSIS OF BIOCOMPATIBILITY OF MATERIALS FOR NON-REMOVABLE AESTHETIC PROSTHETIC STRUCTURES by P.Z. Ozhohan, Z.R. Ozhogan

“… Background. Currently, zirconium dioxide and metal-free ceramics are widely used in orthopedic dentistry. …”
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Optimizing heavy crude oil conversion: Catalytic thermolysis with TiO2@α-Fe2O3 nanocomposite and surfactant dynamics by Asmaa S. Morshedy, Tahany Mahmoud

“…Currently, as the production of light crude oil is reaching its peak, the focus of the petroleum industry is shifting towards significant amount of heavy oil to meet the increasing need for energy and fuels. …”
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Evaluation of silicon nitride as a substrate for culture of PC12 cells: an interfacial model for functional studies in neurons. by Johan Jaime Medina Benavente, Hideo Mogami, Takashi Sakurai, Kazuaki Sawada

“…Silicon nitride is a biocompatible material that is currently used as an interfacial surface between cells and large-scale integration devices incorporating ion-sensitive field-effect transistor technology. …”
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How Two English Primary Schools Promote Wellbeing by Jane Jones

“…We currently inhabit a landscape of worry and pressure, often emanating from messages from news and social media that impact on children’s lives. …”
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Factor-H-related protein 1 (FHR1), a promotor of para-inflammation in age-related macular degeneration by Andjela Sekulic, Sarah M. Herr, Kelly Mulfaul, Inga-Marie Pompös, Silvia Winkler, Carola Dietrich, Benedikt Obermayer, Robert F. Mullins, Thomas Conrad, Peter F. Zipfel, Florian Sennlaub, Christine Skerka, Olaf Strauß

“…Polymorphisms in complement factor-H increase, while absence of factor-H-related protein-1 (FHR1) decreases the AMD risk, currently explained by their opposing relationship. …”
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Soil Decomposer Can Regulate the Legacy Effect of Photodegradation on Forest Marcescent Litter Decomposition, but Emerging Microplastics Disrupt This by Kai Tian, Xin Wang, Rumeng Ye, Yingqi Wang, Zhicheng Chen, Xiaojing Liu, Wenxia Wang, Lunguang Yao

“…ABSTRACT Photodegradation—photochemical mineralization of standing litters—often exerts a legacy effect aiding biodegradation in soil (PLE), which is overlooked in deciduous forests containing marcescent leaves. Meanwhile, increasing anthropogenic microplastics have deposited in forests, how they would affect the PLE on subsequent litter bio‐decomposition is currently unknown. …”
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Bcl-2 Overexpression Improves Survival and Efficacy of Neural Stem Cell-Mediated Enzyme Prodrug Therapy by Rachael Mooney, Asma Abdul Majid, Daniel Mota, Adam He, Soraya Aramburo, Linda Flores, Jennifer Covello-Batalla, Diana Machado, Joanna Gonzaga, Karen S. Aboody

“…However, like other stem cell-based therapies, survival of therapeutic NSCs after transplantation is currently suboptimal. One approach to prolonging cell survival is to transiently overexpress an antiapoptotic protein within the cells prior to transplantation. …”
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Effects of Metamorphic Degree of Coal on Coal Dust Wettability and Dust-Suppression Efficiency via Spraying by Pengfei Wang, Han Han, Ronghua Liu, Yongjun Li, Xuanhao Tan

“…According to the experimental results of coal’s microproperties, with the improvement of metamorphic degree, the content of hydrophilic oxygen-containing functional groups on the surface, the surface roughness, the specific surface area, and the interpore diameter all decreased. …”
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The Influence of Exometabolites of Fungus Botrytis Cinerеa on the Growth of Chinese Cabbage’s Callus Tissue (Brassica Pekinensis) by NGUYEN THI VUONG, E. A. KALASHNIKOVA

“…Currently vegetable crop loss from fungal, bacterial and viral diseases during storage and cultivation is a large proportion, sometimes even 100%. …”
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Optimal Operation Strategy of Ship Power System Under Battle Damage for Enhancing Survivability in Long-Term Missions by Chunhan Bai, Yun Tan, Fanrong Wei, Xiangning Lin

“…After a ship suffers an external strike, the system is often in a poor state of battle damage. Currently, the support capacity of the system in all aspects decreases dramatically, the operation interval narrows, and it is not easy to ensure the completion of the long-term mission chain, especially when it involves impact loads, which is more significant. …”
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The Effect of Organic Acid Modification on the Pore Structure and Fractal Features of 1/3 Coking Coal by Jiafeng Fan, Feng Cai

“…Following treatment with organic acids, the coal samples exhibit an increase in surface fractal dimension, a reduction in spatial fractal dimension, a decline in micropore volume proportion, and a rise in the proportions of transitional and mesopore volumes, and the structure of the hydroxyl group and oxygen-containing functional group decreased. This indicates that treating coal samples with organic acids enhances their pore structure and chemical structure. …”
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Molecular mechanisms underlying Tao-Hong-Si-Wu decoction treating hyperpigmentation based on network pharmacology, Mendelian randomization analysis, and experimental verification by Jun Chen, Wenyi Ye

“…These cells were exposed to graded concentrations of THSWD-containing serum (2.5%, 5%, 10%, 15%, 20%, 30%, 40%, and 50%) and treated with α-MSH (100 nM) to induce an in vitro hyperpigmentation model. …”
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Analysis of the genetic variance of fibre diameter measured along the wool staple for use as a potential indicator of resilience in sheep by Erin G. Smith, Dominic L. Waters, Samuel F. Walkom, Sam A. Clark

“…Sheep are frequently exposed to diverse extensive environments but currently lack appropriate measures of resilience (or sensitivity) towards environmental disturbance. …”
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The Influence of Exometabolites of Fungus Botrytis Cinerеa on the Growth of Chinese Cabbage’s Callus Tissue (Brassica Pekinensis) by NGUYEN THI VUONG, E. A. KALASHNIKOVA

“…Currently vegetable crop loss from fungal, bacterial and viral diseases during storage and cultivation is a large proportion, sometimes even 100%. …”
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Cyclosporine A Loaded PLGA Nanoparticles for Dry Eye Disease: In Vitro Characterization Studies by Vijay D. Wagh, Dipak U. Apar

“…Dry eye disease is a common disease of the tear film caused by decreased tear production or increased evaporation. …”
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