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3581
Effects of coix seed polyphenol extract on rumen fermentation, milk production, fatty acid profile, antioxidant activity, and polyphenol content in dairy goats
Published 2025-03-01“…Overall, the appropriate supplemental level of CSE was 1.5 g/kg in dairy goats under the conditions of the current experiment.…”
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3582
STAT2/SLC27A3/PINK1-Mediated Mitophagy Remodeling Lipid Metabolism Contributes to Pazopanib Resistance in Clear Cell Renal Cell Carcinoma
Published 2024-01-01“…While tyrosine kinase inhibitors (TKIs) are currently the first-line treatments for advanced/metastatic ccRCC, patients often develop resistance after TKI therapy. …”
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3583
The methyl-CpG binding domain 2 regulates peptidylarginine deiminase 4 expression and promotes neutrophil extracellular trap formation via the Janus kinase 2 signaling pathway in e...
Published 2025-12-01“…Objective The prognosis for severe asthma is poor, and the current treatment options are limited. The methyl-CpG binding domain protein 2 (MBD2) participates in neutrophil-mediated severe asthma through epigenetic regulation. …”
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3584
Food Application of Orange Seed Powder through Incorporation in Wheat Flour to Boost Vitamin and Mineral Profiles of Formulated Biscuits
Published 2023-01-01“…In the current work, orange seed powder replaced wheat flour at 0, 2.5, 5, 7.5, and 10% levels, to observe changes in physicochemical features of developed biscuits. …”
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3585
Improvement of the perovskite photodiodes performance via advanced interface engineering with polymer dielectric
Published 2025-04-01“…IV curve analysis and 2-diode model calculations showed enhanced shunt properties, a decreased non-ideality factor, and reduced saturation dark current. …”
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3586
Design and Synthesis of Bis-Chalcones as Curcumin Simplified Analogs and Assessment of Their Antiproliferative Activities Against Human Lung Cancer Cells and <i>Trypanosoma cruzi</...
Published 2025-03-01“…<b>Background: </b>Anticancer therapies represent the primary treatment option for a significant number of cancer patients globally; however, many of these treatments are associated with severe side effects as they target molecular structures present in both cancerous and healthy cells. In a similar context, the treatment of Chagas disease, a neglected tropical illness, is hindered by the high toxicity of the currently available drugs. …”
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3587
Direct oral penicillin challenge in secondary care with low-risk patients: the SPACE mixed-methods study with cost-effectiveness analysis
Published 2025-04-01“…To explore practical aspects of implementing this de-labelling programme in secondary care by investigating factors, such as organisational context, treatment pathway, protocol implementation, time taken and resources. …”
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3588
Digital augmentation of aftercare for patients with anorexia nervosa: the TRIANGLE RCT and economic evaluation
Published 2025-07-01“…Support for the diversity of carers of eating disorders (fathers, partners, siblings) in different cultural contexts across the spectrum of eating disorders The current model of carers support is designed for parents (particularly mothers) of white, highly educated patients with AN. …”
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3589
Effects of temporary erosion control blanket and grass cover on the rates of runoff and sediment in the cut and fill slopes of forest roads using a rainfall simulation test
Published 2024-07-01“…The use of erosion control blankets is a soil bio-engineering method that can effectively reduce runoff and sediment and increase slope stability. Therefore, the current research aimed to temporarily stabilize soil using protective covering treatments, such as jute, straw, wood chips, Festuca grass cover, and nano zeolite super absorbent, to reduce the amount of runoff and sediment. …”
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3590
“Locality – Adaptation” Research of Hydropower Resettlement Communities in the Jinsha River Basin: A Case Study of Ludila Hydropower Station
Published 2025-04-01“…ObjectiveWithin human – environment systems, river basins constitute the earliest geographical units of human activity and currently represent the most critical zones of strained human – environment interactions. …”
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3591
On the added value of sequential deep learning for the upscaling of evapotranspiration
Published 2025-08-01“…In particular, we investigate three questions regarding the performance of the sequential models compared to the non-sequential models in the context of spatial upscaling: (a) whether they lead to more realistic and robust global and regional ET, (b) whether they are able to capture the temporal dynamics of ET better, and (c) how robust they are to the covariate setup and training data subsets.…”
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3592
Key Drivers Affecting the Future of Power Relations in Tehran Metropolis with a Scenario-Writing Approach
Published 2024-09-01“…Given this context, the central question guiding the present research was this: What are the drivers and future scenarios of power relations in Tehran Metropolis? …”
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3593
Regulatory culture and architectural project
Published 2024-06-01“…They are attentive to a quality that does not depend on construction solutions or on techno-typological, morphological or physical-chemical characteristics, but which is linked to a system of needs to be satisfied, the outcome of the interaction between construction and cultural, socio-economic and environmental context. Today’s regulatory landscape has expanded, increasing sensitivities to environmental challenges, health and the qualities of living space. …”
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3594
A novel in vitro system for simultaneous infections with hepatitis B, C, D and E viruses
Published 2025-05-01“…Using HEV-infected HuHep mice, we confirmed the antiviral effect of vonafexor, an FXR agonist, that is currently being tested clinically against HBV/HDV. …”
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3595
A Legal Analysis of Liability for the Loss of the Subject Matter of Sale after Contract Termination: A New Inquiry into Sunni Jurisprudence
Published 2025-03-01“…Determining who bears the liability for this loss becomes a contentious issue: should it be the party currently in possession or the rightful owner awaiting the return? …”
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3596
Multi-omics reveals total flavones from Abelmoschus manihot (L.) Medik. [Malvaceae] ameliorate MAFLD via PI3K/AKT/mTOR-mediated autophagy
Published 2025-07-01“…(Malvaceae), abbreviated as TFA, in the context of MAFLD. Ultra-high-performance liquid chromatography-quadrupole orbitrap mass spectrometry (UHPLC-QTOF-MS) was used to identify the metabolites in TFA. …”
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3597
Social Networks Link Prediction Based on Incremental Learning
Published 2025-03-01“…However, the prediction performance of IL−SNLP on Ask Ubuntu and Super User decreases by only 4.54% and 5.25%, respectively, compared to its performance on Math Overflow. …”
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3598
Improving older people’s experiences and safety at transitions of care: the PACT mixed-methods study including RCT
Published 2025-04-01“…This research aimed to understand if increased involvement of older people in their care in hospital would improve the safety and experience of care transitions. …”
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3599
Emotional literacy programme in special schools for children with a learning disability in England: the ZF-SEND feasibility RCT
Published 2024-12-01“…Future work On the basis of the current findings, an application for a full trial will be prepared and submitted with a number of amendments. …”
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3600
Balancing Innovation and Ethics
Published 2025-03-01“…Even DNA testing company 23andMe states, “Currently 23andMe has several features that can reveal genetic evidence of Indigenous American ancestry, although they are not considered a confirmatory test or proof of such ancestry in a legal context.”[7] These companies cannot fully confirm the accuracy of their tests in finding ancestral information and therefore should not be completely relied upon for discovering self-identity. …”
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