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2301
Comparative legal analysis of the labor law status of a higher school lecturer
Published 2024-05-01“…The authors analyze the provisions of the current Russian labor legislation on the work of higher education lecturers in the context of globalization and the intensification of the global financial and economic crisis. …”
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2302
Optimal Scheduling of the Wine-Bottling Process: A Multi-Dependency Model with Hydraulic Considerations
Published 2025-04-01“…This study addresses the optimization of the bottling process in the wine industry, focusing particularly on the filtration stage, which accounts for approximately 30% of the total costs in the value chain. In the context of significant global production, but with challenges arising from declining demand and increasing costs, precise planning becomes necessary to ensure product quality and operational efficiency in order to control and minimize the costs associated with resource usage. …”
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2303
The role of nicotinamide-β-adenine dinucleotide phosphate-H-cytochrome P450 oxidoreductase in the activation of cytochromes
Published 2025-01-01“…The aim of this theoretical study is to investigate the mechanisms of action of these enzymes in the context of metabolism in highly productive animals. …”
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2304
The Application of Graph Neural Networks in Power Systems from Perspective of Perception-Prediction-Optimization
Published 2024-12-01“…With the increasing uncertainty of the generation, transmission, and consumption sides in new power systems, the complexity and scale of power system topology relationship are continuously growing. …”
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2305
OPTIMIZATION OF IMID-BASED THERAPIES
Published 2024-12-01“…In this case, it is clear that multiple myeloma treatment optimization cannot be achieved by considering multiple myeloma treatment only as applying the appropriate drug combination.In order to ensure the optimization of IMID-based therapies, it is necessary to take a broad perspective.This perspective should include the correct selection of the patient to be treated with IMID, the development and implementation of IMID forms that will increase patient compliance, the use of techniques to predict the development of resistance, side effect management during treatment, preventing the increase in disease burden with appropriate maneuvers by following the disease burden after treatment, and drug-free follow-up.It is recommended to avoid thalidomide in the presence of peripheral neuropathy, to prefer other agents instead of lenalidomide in the presence of renal function loss, and to avoid pomalidomide in patients with COPD.Nex-20, a once-monthly subcutaneous formulation of lenalidomide, is expected to be an important breakthrough in improving patient compliance.Prediction of which patients will develop resistance will be very useful in order to have the best treatment outcomes.Calculation of miRNA risk scores, measurement of lenalidomide metabolite levels in urine, measurement of cereblon levels in blood, or immunohistochemical detection of cereblon levels are some of the methods currently being tried to predict disease resistance.Patients who develop anemia should be treated with erythropoietin, skin reactions should be treated with steroids and antihistamines, diarrhea should be treated with loperamide and colestyramine, and in general, the drug should be discontinued and the same dose or a lower dose should be insisted upon.An important part of treatment is maintenance therapy with lenalidomide. …”
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2306
The Association Between Traumatic Brain Injury and the Risk of Cognitive Decline: An Umbrella Systematic Review and Meta-Analysis
Published 2024-11-01“…Background: There is currently increasing interest in the implication of traumatic brain injury (TBI) as a potential risk factor for long-term neurodegenerative conditions, such as dementia and Alzheimer’s disease (AD). …”
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2307
Understanding the effectiveness and underlying mechanisms of lifestyle modification interventions in adults with learning disabilities: a mixed-methods systematic review
Published 2025-02-01“…Following this, the specific interacting contexts and underlying mechanisms were appraised, and the synthesis focused on developing context–mechanism–outcome configurations (CMOCs), which formed the basis of the emerging programme theory. …”
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2308
HNF-1β alleviates podocyte injury in lupus nephritis by maintaining endoplasmic reticulum homeostasis
Published 2024-12-01“…Objective The current study aims to elucidate the critical function of hepatocyte nuclear factor 1-beta (HNF1-β) in lupus nephritis (LN) by investigating its modulation of the Derlin-1/valosin-containing protein (VCP)/VCP-interacting membrane selenoprotein (VIMP) complex, endoplasmic reticulum (ER) stress and podocyte apoptosis.Methods In vitro and in vivo models of LN were established using glomerular podocytes treated with LN serum and MRL/lpr mice, respectively. …”
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2309
Spatial and Developmental Policy Directions Affecting Marine Spatial Planning in the Northern Aegean Sea, Greece
Published 2024-07-01“…A critical stage of each MSP exercise is the exploration of land- and marine-based policy directions and their current or potential repercussions in the marine environment. …”
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2310
Family Interviews Improve Health Service Recommendations in Mortality Review Process: A Mixed‐Methods Assessment
Published 2025-04-01“…Additionally, US policy leaders in maternal child health and health equity provided historical and current context for FIMR family interview funding and enabling legislation (informing the interpretation of study results and specifically referenced within the manuscript).…”
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2311
A Review of Fish Anomalies in Türkiye’s Waters
Published 2024-10-01“…In the context of this review, 34 articles and symposium proceedings were found to belong to fish anomalies in Türkiye’s waters. …”
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2312
Electric Field Calculation and Comparative Analysis of Conventional and Unconventional Transmission Lines
Published 2024-01-01“…Recent studies emphasize the urgent need for advanced structures that improve transmission capabilities. In this context, optimally designed unconventional lines with higher natural power emerge as potential game changers. …”
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2313
Statistical assessment of interrelationship of marriage and divorces to fertility
Published 2025-01-01“…It indicates high practical significance of the research results in the context of the search for fertility growth reserves in the light of the implemented family and demographic policy and achieving Russia’s national development strategies.…”
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2314
Critical Discourse Analysis of My Uncle Jamshid Khan: Whom the Wind Was Always Taking
Published 2023-07-01“…Using Fairclough’s critical discourse analysis, which examines the text at three levels of description, interpretation, and explanation, to the ideologies inside and outside the novel and the type of encounter the novel has with them in the social and political context of Iraqi Kurdistan since the 80s and 90s has been paid. …”
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2315
Challenges of creativity education in the age of digital transformation through the lens of public high school principals and teachers in Egypt
Published 2024-01-01“…Recognizing the significance of creativity in this context, educators have increasingly emphasized its integration into the classroom and school curriculum. …”
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2316
Telehealth coaching in older adults, behavior change, and impacts of the COVID-19 pandemic: analyses from The Brain Health Champion Study
Published 2025-04-01“…IntroductionWhen COVID-19 containment strategies were imposed in March 2020, we became interested in how these restrictions might interfere with brain-healthy behaviors of older adults who were either actively participating in or who had recently completed our telehealth behavior change intervention. …”
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2317
Industrial Maturity of Machine Learning Solutions Within the Food Industry
Published 2025-01-01“…Therefore, this systematic literature review aims at determining the current state of industrial maturity of machine learning-based approaches in the context of food industry, evaluating their readiness for operational use and deployment. …”
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2318
The balance between care and conflict may be key to understanding maternal aggression in canaries
Published 2025-07-01“…While maternal aggression—defined as aggressive interactions from mothers to the offspring within the family context—may be a seemingly maladaptive behaviour, it could also be an adaptive strategy allowing optimal resource allocation for current and future reproduction in the face of evolutionary conflicts of interest. …”
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2319
Circular economy implementation in the electronics sector: a systematic literature review and future research directions
Published 2025-12-01“…The electronics sector (ES), characterised by increasing e-waste, resource scarcity and operational risks, is transitioning towards CE. …”
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2320
Bibliometric Analysis and Overview of Matrix Product States in the Bose-Hubbard Model
Published 2025-03-01“…Context: Quantum many-body systems have been a prominent topic over the past two decades, underpinning advancements in superconductors, ultracold atoms, and quantum computing, among other fields. …”
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