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981
Identification, Evolution and Expression Analyses of the Hox Family in Procambarus clarkii
Published 2025-08-01“…Homeobox genes are ubiquitous in eukaryotic genomes and can be transcribed into a homeodomain of approximately 60 amino acids. Hox genes are currently the most studied class of homeobox genes. …”
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982
Bleomycin: A worthy alternative
Published 2011-01-01“…Context: Lymphangiomas are developmental anomalies presenting mainly in the first two years of life. …”
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983
Teucrium polium induces apoptosis in peripheral blood lymphocytes isolated from human chronic lymphocytic leukemia
Published 2020-01-01“…The activation of apoptosis is one of the main molecular mechanisms responsible for anti-cancer activities of most of the currently studied potential anti-cancer agents, including natural compounds. …”
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984
In Vitro Efficacy of PEI-Derived Lipopolymers in Silencing of Toxic Proteins in a Neuronal Model of Huntington’s Disease
Published 2025-05-01“…<b>Methods:</b> This study aims to investigate the efficacy of siRNA-containing nano-engineered lipopolymers in selectively silencing the <i>HTT</i> expression in a neuronal model expressing a chimeric protein formed by the human mutated exon 1 of the <i>HTT</i> gene, tagged with GFP. …”
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985
Development of an easy non‐destructive particle isolation protocol for quality control of red blood cell concentrates
Published 2025-01-01“…Nevertheless, there is currently no standardized isolation protocol. In a previous publication, we developed a reproducible ultracentrifugation‐based protocol (20,000 × g protocol) that allows to classify red blood cell concentrates into three cohorts according to their vesiculation level. …”
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986
Kavalactones support motivation to move during intensive training in males preparing for military special operations forces
Published 2024-12-01“…Furthermore, the group taking kavalactones first never experienced a significant decrease in Move motivation state (lowest mean score 21.0, highest 28.6, all p ≥ 0.05), while the group receiving kavalactones in the last 2 weeks of the study had Move scores that were statistically lower than baseline (lowest mean score 8.6, highest 25.9, all p ≤ 0.05) at all time points but the last (p = 0.063) after 2 weeks of kavalactones exposure.Conclusions We report a novel finding that kavalactones may support performance by maintaining or rescuing the desire to expend energy in the context of significant physical and mental strain in well-conditioned individuals, even in a context of already normal cortisol, sleep, and mood.…”
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987
The involvement of the synaptic vesicle cycle in homocysteine induced neurotoxicity in vitro and in vivo
Published 2025-05-01“…However, there is currently a lack of comprehensive understanding regarding the molecular mechanisms underlying Hcy-induced neurotoxicity. …”
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988
Preparation, mechanical, and thermal properties of CrNbO4: A novel dual-functional scale to protect RHEAs from oxidation and thermal attack
Published 2025-07-01“…Interestingly, the room temperature thermal conductivity of CrNbO4 is 1.09 W·m−1·K−1 and decreases to 0.45 W·m−1·K−1 at 1473 K, which is lower than that of most of the currently well-known thermal insulation materials. …”
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989
Effects of El Niño and the Positive Indian Ocean Dipole (+IOD) on Health, Food Security, Economics, and Conflict in Low‐ and Middle‐Income Countries in the Indo‐Pacific: A Systemat...
Published 2025-06-01“…ABSTRACT Climate drivers such as the El Niño Southern Oscillation (ENSO) and the Indian Ocean Dipole (IOD) can impact multiple sectors globally. We are currently witnessing the effects of these teleconnections against the backdrop of a changing climate. …”
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990
Federated learning with tensor networks: a quantum AI framework for healthcare
Published 2024-01-01“…In this work, we propose a federated learning framework based on quantum tensor networks (QTNs) that takes advantage of the principles of many-body quantum physics. Currently, there are no known classical tensor networks (TNs) implemented in federated settings. …”
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991
Case Report: Locally invasive thyroid metastases from renal cell carcinoma: surgery after neoadjuvant therapy
Published 2025-05-01“…Patient 1 received lenvatinib and a bispecific anti–Programmed cell Death protein 1/ cytotoxic T-lymphocyte-associated protein 4 (PD-1/CTLA-4) antibody in the context of a clinical trial. The second patient received nivolumab and cabozantinib.ResultsThe observed tumor response in patient 1 showed a decrease in mean surgical complexity score from unresectable (prevertebral fascia invasion) to severe (risk of recurrent nerve paralysis) and in patient 2 from unresectable (prevertebral fascia) to moderate (superficial esophageal invasion). …”
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992
Anticipating how spatial fishing restrictions in EU waters perform to protect marine species, habitats, and dependent fisheries
Published 2025-07-01“…Our findings emphasize that redistributing fishing effort without reducing overall effort and catches may negate intended decreases in mortality rates of sensitive marine species or restoration of vulnerable marine habitats to the status targeted by the European marine legislation (EU Marine Strategy Framework Directive MSFD). …”
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993
Effects of wetting events on mass timber surface microbial communities and VOC emissions: implications for building operation and occupant well-being
Published 2025-04-01“…IntroductionHumans have used wood as a construction material throughout history. Currently, mass timber products, such as cross-laminated timber (CLT), are becoming more popular as a structural material, since they are renewable and have a lower carbon footprint than concrete or steel. …”
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994
Expression, prognosis and preliminary investigation of the mechanism of action of ACTR6, a member of the ARPs gene family, in hepatocellular carcinoma
Published 2025-03-01“…It is critical to investigate new biomarkers and prognostic variables because there are currently no early diagnostic indicators. Actin-related proteins (ARPs) are involved in transcriptional regulation, chromatin remodeling, and DNA repair—all processes that have been connected to the development of cancer. …”
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995
Nanostructured Strategies for Melanoma Treatment—Part I: Design and Optimization of Curcumin-Loaded Micelles for Enhanced Anticancer Activity
Published 2025-02-01“…<b>Background/Objectives</b>: Melanoma is a pathology that affects a large part of the population, and the currently available therapies have many limitations, including the selective targeting of the site of action. …”
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996
Comparative Ethics of Modern Payment Models
Published 2023-01-01“…This article examines the alignment of current predominant payment models of fee-for-service, capitation, and value-based payments with patient care ethics. …”
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997
Comparative Ethics of Modern Payment Models
Published 2023-01-01“…This article examines the alignment of current predominant payment models of fee-for-service, capitation, and value-based payments with patient care ethics. …”
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998
Optimized biosynthesis and performance enhancement of γ-PGA from Bacillus licheniformis: a study on wettability, microstructure, and environmental performance
Published 2025-07-01“…Infrared spectroscopy analysis showed that the purified product contained typical functional groups of γ-PGA. Changes in the contact angle of γ-PGA solution with coal dust over time demonstrated that brown coal was wetted extremely quickly, with the largest change in contact angle; within 5 min of dropping the fermentation liquid, the contact angle sharply decreased from 69° to 0°, completely wetting the brown coal. …”
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999
Selective Separation of Scandium in Acidic Water Using Carboxyl Functionalized Covalent Phosphonitrile Polymers
Published 2023-10-01“…However, because the pore size of the vast majority of covalent organic polymers currently synthesized is much larger than those of metal ions, this method is generally applicable to larger sized ions such as hydrated uranium ions. …”
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1000
Training Manual for Prevention of Covid-19 Disease among Hospital Personnel
Published 2020-06-01“…Most respiratory droplets containing viruses are in this size range. Medium droplets (10 to 50μm) remain in the air for several minutes. …”
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