<i>MAGE-C1</i> gene and mage-c1 protein expression comparison in primary multiple myeloma patients by E. A. Makunina, L. P. Mendeleeva, V. L. Surin, M. V. Soloviev, M. V. Firsova, A. M. Kovrigina, A. A. Sherstnev, I. V. Gal’tseva, Y. O. Davydova, S. M. Kulikov

“…Single factor analysis showed that patients with decreased MAGE-C1 gene and mage-c1 protein expression levels achieved a significantly higher antitumor response to bortezomib-containing regimens, while high expression was accompanied by refractoriness to bortezomib.…”
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Thrombospondin-I is a critical modulator in non-alcoholic steatohepatitis (NASH). by Jessica Min-DeBartolo, Franklin Schlerman, Sandeep Akare, Ju Wang, James McMahon, Yutian Zhan, Jameel Syed, Wen He, Baohong Zhang, Robert V Martinez

“…Activation of PPARα pathway was supported by observed decrease in serum lipid levels. Our findings provide important insights into the role of TSP-1 in context of NAFLD/NASH and TSP-1 may be a target of interest to develop anti-fibrotic therapeutics for NAFLD/NASH.…”
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Natural Compounds with Beneficial Effects on Skin Collagen Type I and Mechanisms of Their Action by Wioleta Żynda, Agnieszka Ruczaj, Anna Galicka

“…Currently, when the average life expectancy increases, the esthetic aspect and maintaining healthy skin are particularly important. …”
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Banking Models Under the Impact of the Post-Crisis Organizational Changes Apt to Confer Sustainable Financial Stability - Romanian Experience by Claudia Gabriela Baicu, Olimpia State

“…The banking model practiced in Romania continues to be the traditional one. Currently, the most important challenges of the Romanian banking system are the growth of the non-performing loans, the loans in foreign currency to unhedged borrowers, the pressure to meet the Basel III requirements, as well as the possibility that the exposure of foreign banks towards Romania to decrease.…”
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What do we know about digital public debate? Technological affordances and democratic dilemmas by Gulbrandsen Ib T., Just Sine N.

“…We illustrate the resulting six types of participation through a review of empirical studies based in the Nordic context. We summarise what we currently know about digital public debate in a key democratic dilemma: increasing digital participation goes hand in hand with decreasing institutional trust.…”
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Parentage assignment in black soldier fly (Hermetia illucens) using genotyping-by-sequencing by Guyllaume Dufresne, Catherine Bolduc, Christopher Warburton, Grant Vandenberg, Marie-Hélène Deschamps, Nabeel Alnahhas

“…However, this is not currently feasible in mass reared insects like BSF. …”
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SFX-01 is therapeutic against myeloproliferative disorders caused by activating mutations in Shp2 by Hyun-Ju Cho, Joy Smith, Christopher H Switzer, Eleni Louka, Rebecca L Charles, Oleksandra Prysyazhna, Ewald Schroder, Mariana Fernandez-Caggiano, Daniel Simoes de Jesus, Seda Eminaga, Xiaoke Yin, Xiaoping Yang, Steven Lynham, Manuel Mayr, Valle Morales, Katiuscia Bianchi, Vinothini Rajeeve, Pedro R Cutillas, Adam J Mead, Philip Eaton

“…SFX-01, an α-cyclodextrin-stabilized sulforaphane complex currently in clinical development, covalently adducts cysteine residues. …”
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Climate change reduces warming potential of nitrous oxide by an enhanced Brewer‐Dobson circulation by Daniela Kracher, Christian H. Reick, Elisa Manzini, Martin G. Schultz, Olaf Stein

“…N2O is a potent greenhouse gas and the most relevant currently emitted ozone‐depleting substance. Here we examine the implications of a reduced N2O lifetime in the context of climate change. …”
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Thermal and radiative effects on unsteady MHD flow of Casson fluid past a rotating porous medium with variable mass diffusion by J. Prakash, A. Selvaraj, P. Ragupathi, Qasem M. Al-Mdallal, S. Saranya

“…The findings indicate that buoyancy forces imparted by the Grashof numbers considerably increase the velocity due to convection currents. However, the magnetic parameter counteracts velocity due to the Lorentz force while larger porosity increases fluid flow. …”
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HIGH VOLUME BRICK POWDER CONCRETE SYNERGISTIC WITH METAKAOLIN: PHYSICOMECHANICAL PROPERTIES AND DRYING SHRINKAGE by Mahmood Fawzi Ahmed

“…The workability of the mixes containing 10%MK:40%BP and 20%MK:30%BP has slightly decreased, while the mechanical properties were increased and the drying shrinkage were declined. …”
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Molecular identification of Moniliophthora roreri isolates from cocoa orchards in Norte de Santander, Colombia by Liliana Yanet Suárez Contreras

“…The disease destroys the cocoa pod and crop production decreases, the losses reach up to 60% in the department of Norte de Santander. …”
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Exercise Promotes Hippocampal Neurogenesis in T2DM Mice via Irisin/TLR4/MyD88/NF-κB-Mediated Neuroinflammation Pathway by Haocheng Xu, Xin Tian, Yuanxin Wang, Junjie Lin, Baishu Zhu, Chen Zhao, Bin Wang, Xin Zhang, Yu Sun, Nan Li, Xun Sun, Fanxi Zeng, Mingzhi Li, Xiquan Ya, Renqing Zhao

“…Moreover, exercise markedly increased the levels of fibronectin type III domain-containing protein 5 (FNDC5)/irisin protein while decreasing the expression of Toll-like receptor 4 (TLR4), myeloid differential protein-88 (MyD88), and nuclear factor kappa-B (NF-κB) in the hippocampus of T2DM mice. …”
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Morphological features of the poultry thymus by S. V. Huralska, N. V. Dyshliuk, S. S. Zaika, H. P. Hryshchuk, L. H. Yevtukh

“…In this context, there is a change in the ratio of cortical and cerebral substances, the growth of connective tissue stroma and adipose tissue. …”
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The Profile of Multidrug Tuberculosis Regimen and Treatment Outcomes in Pulmonary MDR-TB Patients at the Tertiary Referral Hospital Dr. Soetomo, East Java, Indonesia: A Seven-Year... by Muhamad Frendy Setyawan, Ni Made Mertaniasih, Soedarsono Soedarsono

“…The treatment outcome profile of MDR-TB patients shows the average percentage of cured (15%), died (12%), lost-to-follow-up cases (27%), moved to an individualized regimen or a different health facility (42%), and currently in the evaluation stage (4%). Overall from January 2017 to July  2022, the number of LTFU cases decreased (42, 46, 29, 19, 8, 4)%. …”
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A novel RNN architecture to improve the precision of ship trajectory predictions by Martha Dais Ferreira, Jessica N. A. Campbell

“…Currently, the Ornstein-Uhlenbeck (OU) model is considered the state-of-the-art for STP. …”
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Two decades of cropland monitoring in Changsha-Zhuzhou-Xiangtan city group: trends and future predictions by Wenbo Zhang, Dazhao Fan, Song Ji, Yang Dong, Dongzi Li, Ming Li

“…Rapid urbanization currently poses a threat to cropland areas. Therefore, exploring the pattern of change in cropland areas and its driving mechanism is of great significance in safeguarding regional economic development and food security. …”
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Acute effects of single-bout isometric handgrip exercise on selected cardiovascular parameters in young normotensive adults at a tertiary care center of West Bengal by Anisha Dutta, Anish Bhowmik

“…Context: Hypertension is currently prevalent along with other lifestyle disorders, which further adds up to cardiovascular morbidity. …”
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"Glowing head" mice: a genetic tool enabling reliable preclinical image-based evaluation of cancers in immunocompetent allografts. by Chi-Ping Day, John Carter, Zoe Weaver Ohler, Carrie Bonomi, Rajaa El Meskini, Philip Martin, Cari Graff-Cherry, Lionel Feigenbaum, Thomas Tüting, Terry Van Dyke, Melinda Hollingshead, Glenn Merlino

“…Preclinical therapeutic assessment currently relies on the growth response of established human cell lines xenografted into immunocompromised mice, a strategy that is generally not predictive of clinical outcomes. …”
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Factor-H-related protein 1 (FHR1), a promotor of para-inflammation in age-related macular degeneration by Andjela Sekulic, Sarah M. Herr, Kelly Mulfaul, Inga-Marie Pompös, Silvia Winkler, Carola Dietrich, Benedikt Obermayer, Robert F. Mullins, Thomas Conrad, Peter F. Zipfel, Florian Sennlaub, Christine Skerka, Olaf Strauß

“…Polymorphisms in complement factor-H increase, while absence of factor-H-related protein-1 (FHR1) decreases the AMD risk, currently explained by their opposing relationship. …”
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Soil Decomposer Can Regulate the Legacy Effect of Photodegradation on Forest Marcescent Litter Decomposition, but Emerging Microplastics Disrupt This by Kai Tian, Xin Wang, Rumeng Ye, Yingqi Wang, Zhicheng Chen, Xiaojing Liu, Wenxia Wang, Lunguang Yao

“…ABSTRACT Photodegradation—photochemical mineralization of standing litters—often exerts a legacy effect aiding biodegradation in soil (PLE), which is overlooked in deciduous forests containing marcescent leaves. Meanwhile, increasing anthropogenic microplastics have deposited in forests, how they would affect the PLE on subsequent litter bio‐decomposition is currently unknown. …”
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