Chlorpromazine directly inhibits Kv1.3 channels by facilitating the inactivation of channels by Seo-In Park, Soobeen Hwang, Young Lee, Hee-Yoon Lee, Soohyun Kim, Junseo Hong, Su-Hyun Jo, Se-Young Choi

“…The antipsychotic chlorpromazine (CPZ) demonstrates anti-inflammatory effects by decreasing Kv1.3 activity in mPFC microglia. However, the precise mechanism of CPZ’s effect in the mPFC remains unclear, given that CPZ is known to inhibit dopamine receptors and the mPFC contains various cell types with dopamine receptors. …”
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Persistent anti-NY-ESO-1-specific T cells and expression of differential biomarkers in a patient with metastatic gastric cancer benefiting from combined radioimmunotherapy treatmen... by Deepak Kumar, Said Dermime, Maysaloun Merhi, Afsheen Raza, Varghese Philipose Inchakalody, Kodappully S Siveen, Fairooz Sahir, Sarra Mestiri, Shereena Hydrose, Niloofar Allahverdi, Munir Jalis, Allan Relecom, Lobna Al Zaidan, Mohamed Sir Elkhatim Hamid, Mai Mostafa, Abdul Rehman Zar Gul, Shahab Uddin, Mohammed Al Homsi

“…Combined radioimmunotherapy is currently being investigated to treat patients with cancer. …”
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Improved lubricating and corrosion resistance of MAO coatings on ZK61 Mg alloy by co-doping with graphite and nano-zirconia by Chao Yang, Liyuan Sheng, Chaochao Zhao, Pinghu Chen, Wentai Ouyang, Daokui Xu, Yufeng Zheng, Paul K. Chu

“…Graphite doping decreases the friction coefficient, while ZrO2 doping decreases the wear rate. …”
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C18:0 GM3 ganglioside’s efficacy in LPS-induced parkinsonism: neuroprotection, inflammatory inhibition and gliosis mitigation by Tsung-Ta Liu, Cheng-Tsung Liu, I-Hsun Li, Yu-Chieh Chu, Hao-Yuan Hung, Chuang-Hsin Chiu, Ta-Kai Chou, Shiao-Yun Li, Tin-An Wang, Jui-Hu Shih

“…Abstract Background Parkinson’s disease (PD) is an incurable neurological disorder, and current pharmacological therapies primarily address symptoms without halting disease progression. …”
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Low drying temperature has negligible impact but defatting increases in vitro rumen digestibility of insect meals, with minor changes on fatty acid biohydrogenation by Manuela Renna, Mauro Coppa, Carola Lussiana, Aline Le Morvan, Laura Gasco, Lara Rastello, Jonas Claeys, Gaëlle Maxin

“…Abstract Background Insect meals have been identified as innovative and sustainable feedstuffs that could be used in ruminant nutrition. However, current research on the effects that their processing may have on rumen digestibility and fatty acid (FA) biohydrogenation is scant. …”
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Effect of increasing supplementation of dietary glycine on growth performance, meat quality, liver characteristics, and intestinal health in broiler chickens raised under heat stre... by Sung Hoon Kwon, Ji Hye Lee, Hyun Woo Kim, Deok Yun Kim, Dong Yong Kil

“…ABSTRACT: The current study aimed to investigate the effect of increasing supplementation of dietary glycine (Gly) on growth performance, meat quality, liver characteristics, and intestinal health in broiler chickens raised under heat stress (HS) conditions. …”
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A mixed-methods nutrition, water, sanitation and hygiene knowledge, attitudes, and practices survey of IDPs, returnees, and host community members in four counties of Jonglei state... by Lynn Lieberman Lawry, Rachel Gabor, Jacques Katele, Lazarus Baak Madut, Katina Sommers, David Manuel, Claire Nadolski, Mounir Lado, Tracey Perez Koehlmoos, William Clemmer

“…Improved flood resistant sources for clean water, clean covered water storage container distribution, improved sanitation, oral rehydration solution (ORS) and zinc distribution and education are necessary to decrease diarrheal rates.…”
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Digital currency: features of regulation in the Russian Federation by T. E. Rozhdestvenskaya, A. G. Guznov

“…The article examines the main approaches to the regulation of digital currencies, studies the phenomenon of digital currency itself, assesses the circumstances that aroused massive interest and enthusiasm for cryptocurrencies. An analysis of current positive legal material is presented, in particular, the approach to the regulation of digital currency contained in the Russian Federal Law of July 31, 2020 No. 259- FZ "On digital financial assets, digital currency and on amendments to certain legislative acts of the Russian Federation". …”
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Beyond the brain: early autonomic dysfunction in Alzheimer’s disease by Carmen Nanclares, Inés Colmena, Alicia Muñoz-Montero, Andrés M. Baraibar, Ricardo de Pascual, Aneta Wojnicz, Ana Ruiz-Nuño, Antonio G. García, Adrián Gironda-Martínez, Luis Gandía

“…These changes were accompanied by diminished sodium (INa), calcium (ICa), and nicotinic (IACh) currents, compromising CC excitability. With age, a shift toward increased potassium (IK) currents and enhanced catecholamine secretion may reflect compensatory adaptations aimed at preserving output. …”
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What type of leadership is more effective for managing change during force majeure? Achieving organizational effectiveness during the pandemic by Nazia Habib, Shaheryar Naveed, Muhammad Mumtaz, Rabia Sultana, Shoaib Akhtar

“…Hence, it was important to identify effective leadership styles to successfully manage the transformational process during the period. Therefore, the current study aims to explore and compare the effectiveness of transformational and ethical leadership (EL) in terms of achieving organizational goals during COVID-19 in public and private sector organizations in Pakistan. …”
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THE IMPACT OF THE USE OF BIOFUELS ON CO2 EMISSIONS AT THE LEVEL OF EUROPEAN COUNTRIES FROM THE PERSPECTIVE OF ABSOLUTE DECOUPLING by Valentina SIMION, Liviu MARCUTA, Maricel CAZACU, Nicolae MINEA, Camelia HODOAȘAN

“…Decoupling economic growth from CO2 emissions completely is still a key goal of sustainability programs. According to the current research, nations with faster energy transitions and advanced technologies typically see a sharper decoupling, meaning that real GDP growth is attained without a rise in greenhouse gas emissions. …”
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Adverse birth outcome research case definitions associated with maternal HIV and antiretroviral drug use in pregnancy: a scoping review by Kopano R. Dube, Shani T. de Beer, Kathleen M. Powis, Michael McCaul, Amy L. Slogrove

“…In conjunction with good reporting, variation in adverse birth outcome definitions can be decreased to facilitate comparability of studies as well as pooling of data for enhanced evidence synthesis.…”
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Application of urinary peptide-biomarkers in trauma patients as a predictive tool for prognostic assessment, treatment and intervention timing by Gökmen Aktas, Felix Keller, Justyna Siwy, Agnieszka Latosinska, Harald Mischak, Jorge Mayor, Jan Clausen, Michaela Wilhelmi, Vesta Brauckmann, Stephan Sehmisch, Tarek Omar Pacha

“…Preemptive personalized treatment aimed at preventing these events is a crucial objective of patient management; however, the currently available scoring systems provide only moderate guidance. …”
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The prognostic value of serum apolipoprotein A1 levels in elderly patients with de novo SARS-CoV-2 omicron infection by Cong Shi, Ruishuang Ma, Miao Zhou, Shujun Yang, Shengping Gong

“…The omicron variant is currently the predominant strain circulating worldwide. …”
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Ginkgo ketone ester tablets for the treatment of cognitive impairment associated with chemotherapy for breast cancer - a prospective cohort study by Jiajing Chen, Lixin Chen, Kexin Jiang, Dandan Wang, Chunyu Wu, Yuenong Qin, Sheng Liu

“…BackgroundChemotherapy-related cognitive impairment (CRCI) affects up to 75% of breast cancer patients during treatment, with 35% experiencing persistent post-treatment deficits. Current interventions show limited efficacy, creating urgent need for targeted therapies. …”
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Biostimulation through natural biological inputs on fruiting, nutrient availability and rhizosphere microbiome in legume intercropped ‘Sweet Charlie’ strawberry (Fragaria × Ananass... by Pramod Kumar, Rajeshwar Singh Chandel, Subhash Chander Verma, Nisha Sharma, Simran Saini, Rohit Bishist, Suman Lata

“…Liquid microbial culture of Jeevamrit contained cow dung-urine (pH-5.65, EC-0.23 dS/m) and was enriched with Azotobacter chroococcum, Pseudomonas species and actinobacteria. …”
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Évaluer les gains langagiers dans le cadre d’un apprentissage informel à l’étranger by Eva Donohoe

“…The VEPT showed an overall decrease of 7.59% in oral production, in contrast to the CAF analysis, which revealed significant gains in fluency and accuracy for students who went abroad. …”
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P22 | EXPLORING THE UNEXPECTED DUAL ROLE OF GARLIC DERIVATIVES IN REGULATING INVASIVENESS IN BREAST CANCER SUBTYPES

“…However, studies fail to account for the high heterogeneity within triple-negative breast cancer (TNBC), and no data are currently available about its effects on HER2+ tumors, which, despite recent therapeutic advances, frequently develop resistance. …”
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The impacts of climate variability on conflict risk in conflict-prone regions worldwide by Xiaolan Xie, Fangyu Ding, Mengmeng Hao, Jun Zhuo, Shuai Chen, Jiajie Wu, Jiping Dong, Kai Sun, Qian Wang, Dong Jiang

“…Our results contribute to a better understanding of climate-conflict linkages in conflict-prone countries, which may partly explain the divergent findings of current research and highlight the importance of speeding up the work of adaption for global warming.…”
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Dietary Passion Fruit Seed Oil Supplementation for Health and Performance of Laying Hens by Laís Garcia Cordeiro, Paola Aparecida Damázio Rodrigues, Gabrieli Andressa de Lima, Elis Omar Figueroa Castillo, Joyce Andrade da Silva, Júlia de Lima Lopes, Anna Luísa Lang, Samir Moura Kadri, Antônio Celso Pezzato, José Roberto Sartori

“…The groups were fed a corn–soybean basal diet containing 0.00%, 0.45%, and 0.90% PFSO for 16 weeks. …”
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