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341
Progress of arylacetamide deacetylase research in metabolic diseases
Published 2025-05-01“…It plays a significant role in drug metabolism, lipid metabolism, and the pathogenesis of various diseases. In the context of drug metabolism, AADAC is vital for ensuring the safety of ester-based drugs. …”
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342
Beyond the brain: early autonomic dysfunction in Alzheimer’s disease
Published 2025-06-01“…These changes were accompanied by diminished sodium (INa), calcium (ICa), and nicotinic (IACh) currents, compromising CC excitability. With age, a shift toward increased potassium (IK) currents and enhanced catecholamine secretion may reflect compensatory adaptations aimed at preserving output. …”
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343
What type of leadership is more effective for managing change during force majeure? Achieving organizational effectiveness during the pandemic
Published 2023-11-01“…Originality/value – The study has carried out the comparative analyses in three different ways, including leadership styles (transformational and ethical), type of organization (private and public) and time frames (pre and during COVID-19), which is a true contribution of the research in the Pakistani context.…”
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344
THE IMPACT OF THE USE OF BIOFUELS ON CO2 EMISSIONS AT THE LEVEL OF EUROPEAN COUNTRIES FROM THE PERSPECTIVE OF ABSOLUTE DECOUPLING
Published 2025-01-01“…Decoupling economic growth from CO2 emissions completely is still a key goal of sustainability programs. According to the current research, nations with faster energy transitions and advanced technologies typically see a sharper decoupling, meaning that real GDP growth is attained without a rise in greenhouse gas emissions. …”
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345
Adverse birth outcome research case definitions associated with maternal HIV and antiretroviral drug use in pregnancy: a scoping review
Published 2024-12-01“…Abstract Background Adverse birth outcomes (preterm birth, low birth weight, small for gestational age, and stillbirth) seem to persist in infants born to people with HIV, even in the context of maternal antiretroviral therapy. However, findings have been disparate, inconclusive, and difficult to compare directly across settings, partly owing to variable outcome definitions. …”
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346
Application of urinary peptide-biomarkers in trauma patients as a predictive tool for prognostic assessment, treatment and intervention timing
Published 2025-01-01“…The results obtained allow the planning of a well-powered prospective trial investigating the value of urinary peptides in this context in more detail.…”
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347
Précipitations intenses sur le Bassin Méditerranéen : quelles tendances entre 1950 et 2013 ?
Published 2016-01-01“…In the current context of global warming, changes in intense Mediterranean precipitation events remain less obvious, with no significant evolutions in the number and intensities of such events. …”
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348
The transcriptional activator LdtR from 'Candidatus Liberibacter asiaticus' mediates osmotic stress tolerance.
Published 2014-04-01“…The causal agent of Huanglongbing disease, 'Candidatus Liberibacter asiaticus', is a non-culturable, gram negative, phloem-limited α-proteobacterium. Current methods to control the spread of this disease are still limited to the removal and destruction of infected trees. …”
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349
Vibration energy harvesting by ferrofluids in external magnetic fields
Published 2025-07-01“…Abstract The development of wearable electronics and the current era of big data requires the sustainable power supply of numerous distributed sensors. …”
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350
Tasks of practical content as a means of qualitative mathematical training of education seekers
Published 2024-03-01“…Article contains an analysis of the reasons for the decrease in the motivation of students in the study of mathematics and methods for solving this problem. …”
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351
The impact of information technologies and artificial intelligence on economic growth: An analysis of theoretical approaches
Published 2025-03-01“…Additionally, market dynamism has been declining, which results in lower firm entry and exit rates, alongside a decrease in labour mobility. Purpose. The article aims at analyzing current studies that explore the lack of notable macroeconomic effects from IT and AI proliferation. …”
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352
The legal nature of crypto assets and its reflection in the civil and tax legislation of the Russian Federation
Published 2024-09-01“…Without clear and unambiguous legal regulation, it is difficult to ensure proper control and taxation of transactions with crypto assets, which can lead to significant tax losses and a decrease in budget revenues.Moreover, the concept of “digital currency” used in Russian legislation does not correspond to the generally accepted meaning in international practice and is mainly considered in an economic context, rather than in a legal one. …”
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353
Numerical Study of the Effects of Inlet Geometry on the Performance of the Sediment Bypass Tunnel using SSIIM Numerical Model
Published 2023-07-01“…Sediment Bypass Tunnels (SBTs) are deviant channels that convey the current containing sediments from the upstream to the downstream of the reservoir. …”
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354
The prognostic value of serum apolipoprotein A1 levels in elderly patients with de novo SARS-CoV-2 omicron infection
Published 2025-07-01“…The omicron variant is currently the predominant strain circulating worldwide. …”
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355
Pathogenetic justification of sacubitril / valsartan use in respiratory-cardial comorbidity
Published 2023-01-01“…Natriuretic peptide is currently a recognized marker of heart failure, the high value of which is achieved for determining the prognosis and stratification of the risk of heart failure. …”
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356
Influence of green information on environmental awareness: a case study of clothing tags
Published 2025-03-01“…This positions the fashion industry as the second-largest polluting industry in the world. Currently, due to consumers’ green consumption behaviors are influenced by the source of label information, recognition of eco-labels, and academic literature contains limited research on the design and perspectives of green information integrated into clothing tags. …”
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357
The bacterial microbiome in spider beetles and deathwatch beetles
Published 2025-05-01“…ABSTRACT The beetle family Ptinidae contains a number of economically important pests, such as the cigarette beetle Lasioderma serricorne, the drugstore beetle Stegobium paniceum, and the diverse spider beetles. …”
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358
Molecular mechanisms underlying Tao-Hong-Si-Wu decoction treating hyperpigmentation based on network pharmacology, Mendelian randomization analysis, and experimental verification
Published 2024-12-01“…Context Hyperpigmentation, a common skin condition marked by excessive melanin production, currently has limited effective treatment options.Objective This study explores the effects of Tao-Hong-Si-Wu decoction (THSWD) on hyperpigmentation and to elucidate the underlying mechanisms.Materials and methods We employed network pharmacology, Mendelian randomization, and molecular docking to identify THSWD’s hub targets and mechanisms against hyperpigmentation. …”
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359
Oral history as a citizen science tool to understand biodiversity loss and environmental changes: on firefly extirpation in Morelia, Michoacán, Mexico
Published 2025-05-01“…In contrast, the younger generation of Morelians showed lower interaction and recognition of these insects in nature, which could be related to the loss of collective memory over generations and the shifting baseline syndrome. Conclusions In contexts where historical scientific data are not available, we suggest that fireflies can be used to assess the history of natural environments and changes in the populations of these insects. …”
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360
ISSUES AND TRENDS OF PROGRESS TOWARDS SUSTAINABLE DEVELOPMENT GOALS IN ROMANIA
Published 2020-01-01“…Monitoring SDG 12 in an EU context focuses on progress made in decoupling environmental impacts from economic growth, in decreasing energy consumption and in tackling waste generation and management. …”
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