Overcoming immunosuppression in cancer: how ketogenic diets boost immune checkpoint blockade by Victoria E. Stefan, Daniela D. Weber, Roland Lang, Barbara Kofler

“…., high-fat low-carbohydrate diets, have been shown to have antiproliferative and immunomodulatory effects in various preclinical cancer studies. Here, we review current knowledge of the complex interplay of KDs and the anti-tumor immune response in the context of ICB therapy, to update our understanding of diet-induced immunometabolic reprogramming in cancer. …”
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Horticultural performance and QTL mapping of snap bean (Phaseolus vulgaris L.) populations with organic and conventional breeding histories by Hayley E. P. Richardson, Ryan M. King, Joel Davis, James R. Myers

“…IntroductionImproving crop cultivars for use on organic farms is pertinent, as current elite germplasm is less resilient within the more variable context of organic farm environments. …”
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Cluster-randomized trial of the implementation of the Responses to Illness Severity Quantification (RISQ) system in children with acute malnutrition 6 to 59 months of age in Ngouri... by Nancy M. Dale, Youssouf Djidita Hagre, Susan Shepherd, George Tomlinson, Stanley Zlotkin, Masra Ngaradoum, Mahmat Bechir, Marius Madjissem, Charles Tehoua, Christopher Parshuram

“…Abstract Background The Responses to Illness Severity Quantification (RISQ) System is a scientifically developed clinical decision support tool comprised of four parts: (1) a validated 7-item severity of illness score, (2) age-specific documentation forms, (3) context-relevant score-matched recommendations, and (4) implementation programming. …”
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Laboratory assays do not consistently indicate under processing of soybean meal that negatively impacts broiler performance by K.M. Bowen, L.E. Knarr, E.A. Lynch, E.B. Estanich, A.K. Renner, H.B. Krishnan, J.S. Moritz

“…Urease decreased with increasing processing according to 2 of the 3 laboratories. …”
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Catalytic Decomposition of CF4 by Mesoporous Aluminum Coupled with Non-Thermal Plasma by Fenghua SHEN, Yuqin LI, Wanning LIU, Kaisong XIANG, Hui LIU

“…These products deposit on the catalyst surface, leading to pore blockage and a subsequent decrease in CF4 decomposition efficiency after prolonged reaction. …”
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Genotypes and spatial configurations of public art museums in Japan by Yunfei Xie, Muhan Shen, Nobuaki Furuya

“…The social role of museums has continued to shift according to evolving social, economic, and cultural contexts. The transition from a single exhibition educational role to a more diversified role presents challenges in terms of the spatial configuration of museums, thereby highlighting areas for broadening the current understanding of spatial layouts. …”
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Neutrophil-to-Lymphocyte ratio as surrogate for JAK2V617F suppression and event-free survival in polycythemia vera by Tiziano Barbui, Arianna Ghirardi, Victoria Empson, Francesca Fenili, Giuseppe Gaetano Loscocco, Annalisa Condorelli, Alessandra Iurlo, Daniele Cattaneo, Elena Rossi, Valerio De Stefano, Paola Guglielmelli, Christoph Klade, Heinz Gisslinger, Alessandro Rambaldi, Joseph M. Scandura, Alessandro Maria Vannucchi

“…Abstract Chronic systemic inflammation is a key driver of polycythemia vera (PV) progression, but the immunomodulatory effects of current treatments remain poorly defined. The neutrophil-to-lymphocyte ratio (NLR) is an accessible biomarker of systemic inflammation proven in other contexts, but its role in monitoring PV disease activity has not been established. …”
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Modern ideas about the role of the galaninergic system in the pathogenesis of heart failure and myocardial remodeling by A. A. Yafarova, A. R. Kiselev, A. F. Sheptulina, O. M. Drapkina

“…In this regard, the search for new molecules for therapeutic action aimed at preventing myocardial remodeling is of undoubted interest. In this context, the galaninergic system seems to be a promising target. …”
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COVID-19 Vaccines in the Pediatric Population: A Focus on Cardiac Patients by Ghena Lababidi, Hossam Lababidi, Fadi Bitar, Mariam Arabi

“…This review also contains current and future perspectives, as well as a section on the cardiovascular implications and related dynamics of pediatric COVID-19 vaccination.…”
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ANALYSIS OF MODELS OF EARLY DEBT REPAYMENT IN THE Generalized CREDIT TRANSACTIONS by Y. E. Kasimov, A. N. Kolesnikov

“…So in the uniform schemes of repayment of consumer credit each payment contains the same part of principal amounts and the total interest. …”
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Process Parameter Study on New Electrochemical Chloride Extraction of Corroded Concrete in Marine Environment by HE Lang

“…Experimental results showed that the ECE efficiency increased with the increase of current density, and the optimal current density was 2 A/m2 after overall consideration. …”
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Ethnozootechnical Perspectives on the Decline of Traditional Knowledge About Local Goat and Sheep Breeds in the Semi-Arid Region of Paraíba, Brazil by Raissa C. Silva, Marilene N. Melo, Carlos F. T. de Oliveira, José V. Cardoso, Luis A. C. Cevallos, Laura L. da Rocha, Janaina K. G. Arandas, Maria N. Ribeiro

“…The conservation of local breeds plays a strategic role in maintaining genetic variability, ensuring adaptive responses to environmental challenges, and preserving the cultural and socioeconomic structures of traditional communities. In this context, this study explores the potential disappearance of traditional knowledge about local breeds from an ethnozootechnical perspective. …”
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Jian-Pi-Gu-Shen-Hua-Yu Decoction Alleviated Diabetic Nephropathy in Mice through Reducing Ferroptosis by Shuquan Lv, Lirong Fan, Xiaoting Chen, Xiuhai Su, Li Dong, Qinghai Wang, Yuansong Wang, Hui Zhang, Huantian Cui, Shufang Zhang, Lixin Wang

“…Diabetic nephropathy (DN), one of the most frequent complications of diabetes mellitus, is a leading cause of end-stage renal disease. However, the current treatment methods still cannot effectively halt the progression of DN. …”
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Impacts of CACNB4 overexpression on dendritic spine density in both sexes and relevance to schizophrenia by Emily M. Parker, Nathan L. Kindja, Rebecca A. DeGiosio, Ryan B. Salisbury, Josh M. Krivinko, Claire E. J. Cheetham, Matthew L. MacDonald, Weijia Fan, Bin Cheng, Robert A. Sweet

“…Overexpressing the gene that encodes the voltage-gated calcium channel subunit β4, CACNB4, selectively reduced small spine density in vitro. In the current study we extended this observation in an intact mammalian system within a relevant neurodevelopmental context. …”
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Possibilities of metabolic surgery for the treatment of type 2 diabetes mellitus in patients with grade 1 alimentary obesity by Vladimir V. Salukhov, Nikita S. Ilinskii, Evgenii V. Vasil'ev, Ruslan T. Sardinov, Dmitrii V. Gladyshev

“…Many studies have demonstrated the high effectiveness of bariatric surgery in patients with grade 2–3 obesity and type 2 diabetes mellitus. Currently, surgery is one of the most effective ways to decrease body mass, to maintain long-term weight loss and to manage type 2 diabetes mellitus. …”
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Comparative Study between Pregnant and Non-Pregnant Women Regarding Variation of Liver Function Tests: Assessment of Health Literacy by Amina I. B. Othman, Dalia M. A. Elsherbini, Hayam F. A. Eittah, Manal S. Hakami, Badria M. A. Mohammed

“… Context: Pregnancy is associated with normal physiological adaptive changes. …”
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Effect of Sheet Resistance and Morphology of ITO Thin Films on Polymer Solar Cell Characteristics by Ram Narayan Chauhan, C. Singh, R. S. Anand, Jitendra Kumar

“…The decrease in fill factor, open-circuit voltage is compensated by increased short-circuit current. …”
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High prevalence of the hotspot complement factor I p.Ile357Met pathogenic variant in Tunisian atypical hemolytic uremic syndrome patients: report of three new cases and review of t... by Asma Tajouri, Asma Tajouri, Asma Tajouri, Imen Ayadi, Imen Ayadi, Rimeh BenBrahim, Rimeh BenBrahim, Ikram Mami, Abir Boussetta, Hend Jlajla, Hend Jlajla, Yousr Zerzeri, Haifa Arbi Sassi, Jamila Ben Sassi, Hela Sahli, Lilia Laadhar, Lilia Laadhar, Tahar Gargah, Mohamed Karim Zouaghi, Maryam Kallel Sellami, Maryam Kallel Sellami

“…The recurrence of this variant in the Tunisian cohort led us to suggest that it could be characteristic of the Tunisian population.MethodsIn this context, we conducted the current study which included 8 adults and three children with suspected aHUS and decreased factor I levels, as well as one relative. …”
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SLIPT-Assisted Dual-Hop VLC/RF With Relay Selection: Outage Probability Analysis and Optimization by van Khoe Ta, Ic-Pyo Hong, Giang N. Tran

“…Especially, the devices in optical communication range are randomly located with the uniform distribution, and the light intensity from the light emitting diode (LED) contains alternating current (AC) and direct current (DC) elements for the signal detection and energy harvesting. …”
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Quantitative dynamics of neural uncertainty in sensory processing and decision-making during discriminative learning by Soonho Shin, Joonsu Oh, Sun Kwang Kim, Yong-Seok Lee, Sang Jeong Kim

“…Our model shows that the neural representation of fS1 encodes uncertainties not only from vibratory stimuli but also from decision-making processes, emphasizing its crucial role across various biological contexts. We confirmed that uncertainty decreases as learning progresses and increases with interruptions in learning. …”
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