Investigating The Possibility of Extracting Phenolic Compounds from Raisin Waste with The Aim of Waste Management from Raisin Processing Units by Amir Abbas Matin, Bahar Azimi, Hosein Hashempoor

“…Introduction: Grapes are one of the most important and most productive agricultural harvests in the world. Iran is currently the seventh largest producer of grapes in the world, with over 252,000 hectares of vineyards. …”
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Pharmacological correction of hepatotoxicity induced by anti-tuberculosis drugs by D. S. Sukhanov, E. V. Timofeev, Y. S. Alekseeva, K. A. Nagornova

“…Hepatoprotective drugs of various origin and chemical composition are used for the correction and prevention of drug-induced liver injury. Currently, preparations of plant origin (from milk thistle, licorice, soy), animal origin, preparations of bile acids, and some others are isolated. …”
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Innovation activity in European Union service sector: Similarities or differences? by Kamil Decyk

“…On the other hand, it could contain instruments and tools specific to a given industry. …”
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Amyloidogenic immunoglobulin light chains disturb contractile function and calcium transients in a human cardiac spheroid model of light chain (AL) amyloidosis by Mélanie Bézard, Jean-Sébastien Vartanian-Grimaldi, Julien Henri, Denisa Calin, Amira Zaroui, Mounira Kharoubi, Thibaud Damy, Onnik Agbulut, Ekaterini Kordeli

“…LC-treated hiPSC-CM cultures and LC-containing spheroids presented structural and functional defects including: (1) decreased levels and subcellular disorganization of sarcomeric protein alpha-actinin; (2) abnormal accumulation of calcium handling SERCA2a protein; (3) impaired contractility of spheroids and altered calcium transients. …”
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Teucrium polium induces apoptosis in peripheral blood lymphocytes isolated from human chronic lymphocytic leukemia by Zarić Milan, Živković-Zarić Radica, Mitrović Marina, Nikolić Ivana, Čanović Petar, Milosavljević Zoran, Jovanović Danijela, Zelen Ivanka

“…The activation of apoptosis is one of the main molecular mechanisms responsible for anti-cancer activities of most of the currently studied potential anti-cancer agents, including natural compounds. …”
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Epigenetic therapeutics to overcome resistance against immune checkpoint inhibitors (ICI) in hepatocellular carcinoma (HCC): a proof-of-concept clinical trial by Stephen Chan, Alfred Cheng, Nick La Thangue, David Kerr

“…However, resistance to ICI is increasingly encountered in clinical practice in HCC patients. …”
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Digital Fire and Salvage Unit: A New Level of Training for Emercom Cadets by Igor A. Malyj, Vladislav V. Bulgakov, Irina Yu. Sharabanova

“…The practical training of cadets currently being implemented on the basis of the fire and rescue training unit has a time-limited training format, in the form of a day on duty in three days, which does not allow without the widespread use of digital technologies to increase the level of organization of the educational process and its effectiveness, for example, by ensuring constant access of trainees to educational materials.Materials and methods. …”
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A Comparative Study of the Extraction Methods for the Simultaneous Detection of NPS Groups from Urine by M. Kuloglu Genc, S. Mercan, C. Bulut, Z. Turkmen

“…A total of 1,127 NPS have been reported worldwide as of 2022. The increasing chemical diversity and unprecedented substance numbers of NPS make this phenomenon even more difficult to detect, monitor and understand analytically. …”
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In Vitro Efficacy of PEI-Derived Lipopolymers in Silencing of Toxic Proteins in a Neuronal Model of Huntington’s Disease by Luis C. Morales, Luv Modi, Saba Abbasi Dezfouli, Amarnath Praphakar Rajendran, Remant Kc, Vaibhavi Kadam, Simonetta Sipione, Hasan Uludağ

“…<b>Methods:</b> This study aims to investigate the efficacy of siRNA-containing nano-engineered lipopolymers in selectively silencing the <i>HTT</i> expression in a neuronal model expressing a chimeric protein formed by the human mutated exon 1 of the <i>HTT</i> gene, tagged with GFP. …”
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Development of an easy non‐destructive particle isolation protocol for quality control of red blood cell concentrates by Marine Ghodsi, Anne‐Sophie Cloos, Anaïs Lotens, Marine De Bueger, Patrick Van Der Smissen, Patrick Henriet, Nicolas Cellier, Christophe E. Pierreux, Tomé Najdovski, Donatienne Tyteca

“…Nevertheless, there is currently no standardized isolation protocol. In a previous publication, we developed a reproducible ultracentrifugation‐based protocol (20,000 × g protocol) that allows to classify red blood cell concentrates into three cohorts according to their vesiculation level. …”
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The involvement of the synaptic vesicle cycle in homocysteine induced neurotoxicity in vitro and in vivo by Meng Wang, Xiaoshan Liang, Keqing Jin, Yinyue Liu, Suhui Luo, Qiang Zhang, Xuan Wang, Zhiping Dong, Xumei zhang

“…However, there is currently a lack of comprehensive understanding regarding the molecular mechanisms underlying Hcy-induced neurotoxicity. …”
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Preparation, mechanical, and thermal properties of CrNbO4: A novel dual-functional scale to protect RHEAs from oxidation and thermal attack by Shuang Zhang, Jian Zhang, Xiaohui Wang, Huimin Xiang, Cheng Fang, Wei Xie, Yanchun Zhou

“…Interestingly, the room temperature thermal conductivity of CrNbO4 is 1.09 W·m−1·K−1 and decreases to 0.45 W·m−1·K−1 at 1473 K, which is lower than that of most of the currently well-known thermal insulation materials. …”
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Epidemiological Situation on Cholera in the Russian Federation in 2023 and Forecast for 2024 by A. Yu. Popova, A. K. Noskov, E. B. Ezhlova, V. D. Kruglikov, E. V. Monakhova, O. S. Chemisova, A. A. Lopatin, S. M. Ivanova, O. A. Podoynitsyna, A. S. Vodop’yanov, D. A. Levchenko, I. V. Savina

“…It was established that the toxigenic strains isolated from patients belonged to the currently dominant in the world “post-Haitian” group, including in India and Bangladesh, with the genotype ctxB7 tcpACIRS rtxA4a VSP-IIΔ0495-0512. …”
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Toxicity of ivermectin to bed bugs (Cimex hemipterus) and risk factors associated with infestation in Kwale County, coastal Kenya by Tobias Odongo, Isaiah Omondi, Caroline Wanjiku, Miguel Okoko, Caroline Kiuru, Mercy Kariuki, Isaac Ringera, Bruno Otieno, Festus Mure, Joanna Furnival-Adams, Almudena Sanz Gutierrez, Rachel Otuko, Nelly Regina Rabinovich, Joseph Mwangangi, Carlos Chaccour, Marta Ferreira Maia

“…Ivermectin, an endectocide known to impact various neglected tropical diseases and hematophagous arthropods, is currently being assessed for malaria vector control. …”
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A study of the safety and immunogenicity of a new vaccine for the prevention of COVID-19 based on virus-like particles in phase I clinical trials by Tatiana V. Grebennikova, Olga N. Zaykova, Alexey A. Plotnikov, Lyudmila V. Kostina, Yana Yu. Chernoryzh, Olesia V. Eliseeva, Oleg E. Latyshev, Viktor F. Larichev, Irina T. Fedyakina, Milana A. Losich, Ilya M. Kirillov, Ilya E. Filatov, Marina V. Balandina, Valery V. Tsibezov, Kirill I. Yurlov, Ekaterina I. Lesnova, Valeria M. Kondratieva, Alina A. Kozlova, Marina S. Baranets, Aleksandr L. Gintsburg

“…One of the more promising developments in preventing the spread of infections, including COVID-19, is the production of vaccines based on virus-like particles (VLP). Currently, in the National Research Center for Epidemiology and Microbiology named after N.F. …”
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Expression, prognosis and preliminary investigation of the mechanism of action of ACTR6, a member of the ARPs gene family, in hepatocellular carcinoma by Jing Wang, Meng Song, Jinming Tang, Haoran Yue, Xiaoyang Guo, Zhan Chen, Xiaolan Shen, Mingbo Cao, Mingbo Cao

“…It is critical to investigate new biomarkers and prognostic variables because there are currently no early diagnostic indicators. Actin-related proteins (ARPs) are involved in transcriptional regulation, chromatin remodeling, and DNA repair—all processes that have been connected to the development of cancer. …”
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Fexuprazan safeguards the esophagus from hydrochloric acid-induced damage by suppressing NLRP1/Caspase-1/GSDMD pyroptotic pathway by Seo Yeon Kim, Seo Yeon Kim, Jung-Ho Yoon, Da Hyun Jung, Ga Hee Kim, Chul Hoon Kim, Chul Hoon Kim, Sang Kil Lee

“…Esomeprazole, a representative PPI, and three currently marketed P-CABs (vonoprazan, tegoprazan, and fexuprazan) were used for pretreatment. …”
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Artificial Intelligent Model to Enhance Thermal Conductivity of TiO₂-Al₂O₃/Water-Ethylene Glycol-Based Hybrid Nanofluid for Automotive Radiator by Md. Munirul Hasan, Md. Mustafizur Rahman, Md. Arafatur Rahman, Suraya Abu Bakar, Mohammad Saiful Islam, Tarek Khalifa

“…Vehicular cooling system is one of the priorities for the automobile industry, aiming to achieve sustainability and energy efficiency. Currently, coolants are being utilized in cooling systems that exhibit super heat transfer capabilities. …”
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Presentation of Financial Assets in the Monetary Statistics by V. N. Salin, O. Y. Sitnikova, L. Y. Arhangelskaya

“…The purpose of the study. Currently, the issues of determining, presenting and analyzing indicators of economic assets, in particular, financial ones, are relevant, since financial assets, along with nonfinancial ones, constitute the most important characteristic of national wealth as a level of development of the country and are the basis for constructing national accounts, indicators of monetary statistics and other sections of macroeconomic statistics. …”
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Progress of researches on the internalization of Escherichia coli O157:H7 in plant tissues by Yang Li, Wang Haizhen, Yao Zhiyuan, Wu Jianjun

“…Whether human pathogen currently carries the effector proteins is yet to be determined. …”
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