Deep mutagenesis scanning using whole trimeric SARS-CoV-2 spike highlights the importance of NTD-RBD interactions in determining spike phenotype. by Ruthiran Kugathasan, Ksenia Sukhova, Maya Moshe, Paul Kellam, Wendy Barclay

“…New variants of SARS-CoV-2 are continually emerging with mutations in spike associated with increased transmissibility and immune escape. Phenotypic maps can inform the prediction of concerning mutations from genomic surveillance, however most of these maps currently derive from studies using monomeric RBD, while spike is trimeric, and contains additional domains. …”
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Ghrelin stimulation of growth hormone-releasing hormone neurons is direct in the arcuate nucleus. by Guillaume Osterstock, Pauline Escobar, Violeta Mitutsova, Laurie-Anne Gouty-Colomer, Pierre Fontanaud, François Molino, Jean-Alain Fehrentz, Danielle Carmignac, Jean Martinez, Nathalie C Guerineau, Iain C A F Robinson, Patrice Mollard, Pierre-François Méry

“…Indeed, ghrelin does not modify synaptic currents of GHRH neurons. However, ghrelin exerts a strong and direct depolarizing effect on GHRH neurons, which supports their increased firing rate.…”
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Efficient utilization of high CO2 landfill-gas for syngas generation: Ultra-rich combustion pathways study in porous media reactor via CFD simulation by Mohammadreza Mohammadpour, Amirreza Mohammadpour, Mehdi Ashjaee, Ehsan Houshfar

“…The current investigation explores the possibility of extracting syngas from low-calorific value landfill-gas rich-combustion with pure O2, which contains a considerable amount of CO2 in its composition as an effective strategy in CO2 utilization. …”
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Influence of Age and Neurotoxic HAART Use on Frequency of HIV Sensory Neuropathy by Olajumoke Oshinaike, Akinsegun Akinbami, Oluwadamilola Ojo, Anthonia Ogbera, Njideka Okubadejo, Frank Ojini, Mustapha Danesi

“…On multivariate analyses, the independent associations with SN were increasing age (P=0.03) and current exposure to stavudine (P=0.00). …”
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ASIC2 subunits facilitate expression at the cell surface and confer regulation by PSD-95. by Anne Marie S Harding, Nobuyoshi Kusama, Tomonori Hattori, Mamta Gautam, Christopher J Benson

“…We found that ASIC2 increased cell surface levels of the channel when it is coexpressed with ASIC1a, and genetic deletion of ASIC2 reduced acid-evoked current amplitude in mouse hippocampal neurons. …”
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Electrohydraulic effect of microsecond pulsed discharge in transformer oils by Hang Wang, Cheng Zhang, Zhuofei Wang, Shuai Zhang, Kaihang Guo, Tao Shao

“…With the gap distance increase, all the breakdown voltage, the discharge energy, and the ratio of the mechanical energy to total energy increase, the breakdown current, the acceleration of the container wall, and the velocity of the shock wave decrease. …”
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Systemic hormonal contraception and risk of venous thromboembolism by Oskari Heikinheimo, Elena Toffol, Timo Partonen, Anna But, Antti Latvala, Jari Haukka

“…Abstract Introduction The increased risk of venous thromboembolism associated with the use of hormonal contraception is well recognized, but evidence regarding hormonal contraception containing natural estradiol is limited. …”
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Introduction of Vector-Borne Infections in Europe: Emerging and Re-Emerging Viral Pathogens with Potential Impact on One Health by Jacopo Logiudice, Maria Alberti, Andrea Ciccarone, Benedetta Rossi, Giorgio Tiecco, Maria Antonia De Francesco, Eugenia Quiros-Roldan

“…This review explores the spread of arboviruses in Europe, highlighting their historical context, current transmission dynamics, and their impact on public health.…”
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Immunisation of young children against influenza — evidence review by V. A. Bulgakova, L. R. Selimzyanova, T. E. Privalova, D. A. Yusupova

“…Influenza is a highly contagious viral infection and poses a serious burden, especially for children under 5 years of age due to an increased risk of severe illness and hospitalization. …”
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Influence of fruit stages on chemical compositions, phytochemicals, and antioxidant activity of wood apple (Feronia limonia (L.) Swingle) by Rashmi Srivastava, Neha Mishra, Arshi, Shraddha Tripathi, Smriti, Neha Taslim Fatima, Neetu Mishra

“…Swingle is an underappreciated tropical fruit, contains several vitamins, minerals, and bioactive substances, yet it has received significantly less attention. …”
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Synergistic Effects of Mannan Oligosaccharides and Onion Peels on In Vitro Batch Culture Fermentation of High Concentrate and Forage Diets by Lydia K. Olagunju, Oludotun O. Adelusi, Peter A. Dele, Yasmine Shaw, Rosetta M. Brice, Oluteru E. Orimaye, Jorge A. Villarreal-González, Hye Won Kang, Ahmed E. Kholif, Uchenna Y. Anele

“…The current study evaluated the effect of combining mannan oligosaccharide (MOS) and onion peel (OP) on ruminal in vitro total gas (GP), greenhouse gas emissions, dry matter and fiber fraction digestibility, partitioning factor (PF₂₄; mg degradable DM per mL gas), microbial mass, and volatile fatty acids using two dietary substrates: high forage (HF) and high concentrate (HC) diets. …”
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Metabolizable energy and digestible nutrient values of protease-supplemented field pea for broiler chicken by Tofuko A. Woyengo, Anna Rogiewicz, Robert Patterson

“…The supplemental protease increased (P < 0.05) AMEn values of the SBM and field by an average of 187 kcal/kg but decreased (P < 0.05) the SID values of all indispensable AA (except His) for the SBM and field, by an average of 2.7 percentage points. …”
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Water- and frost-resistance of crushed stone mastic asphalt concrete prepared on sevilen-modified bitumen by V. V. Yadykina, S. N. Navolokina, A. M. Gridchin

“…Introduction. Currently, increasing the durability of road asphalt concrete pavements is one of the urgent issues, the solution of which provides a significant economic effect achieved by increasing the turnaround time, as well as the overall service life of highways. …”
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Effect of phosphorus content on microstructure and magnetic/mechanical properties of ultra-thin non-oriented Fe–3%Si ribbons prepared with planar flow casting by Zhixiang Liu, Deming Xu, Siqian Bao, Gengwei Yang, Qingming Chang

“…After annealing at 925 °C for 30 min, the magnetic induction of the phosphorus-containing ribbons significantly increased and the iron loss decreased. …”
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Comparative Study of Pectin and Kappa-Carrageenan-Based Films Loaded With Boswellic Acid and Acetyl-11-Keto-Beta-Boswellic Acid for Active Packaging by Yasir Abbas Shah, Saurabh Bhatia, Ahmed Al-Harrasi, Mohammad Tarahi, Talha Shireen Khan, Tanveer Alam, Esra Koca, Levent Yurdaer Aydemir

“…Moreover, the water contact angle measurements revealed that the films containing AKBA showed a noticeable increase in contact angles, reflecting an enhancement in hydrophobicity. …”
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PEDIATRIC BRONCHIAL ASTHMA: MODERN TREATMENT ASPECTS by O.V. Zaitseva, О.А. Murtazaeva

“…There is a recent tendency of pediatric asthma morbidity increase, also among infants, as well as increase in its severity. …”
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Hyperbaric Oxygenation, Antihypoxant and Antioxidative Therapy for Acute Myocardial Infarction by G. G. Zhdanov, I. M. Sokolov

“…The paper contains information on the currently available methods for intensive care for acute myocardial infarction (AMI), by using hyperbaric oxygenation (HBO), antihypoxants, and antioxidants. …”
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Dual contribution of ASIC1a channels in the spinal processing of pain information by deep projection neurons revealed by computational modeling. by Magda Chafaï, Ariane Delrocq, Perrine Inquimbert, Ludivine Pidoux, Kevin Delanoe, Maurizio Toft, Frederic Brau, Eric Lingueglia, Romain Veltz, Emmanuel Deval

“…All deep WDR-like neurons recorded from spinal slices exhibit an ASIC current with biophysical and pharmacological characteristics consistent with functional expression of ASIC1a homomeric channels. …”
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Scientific Opinion on Review of the European Union Summary Report on trends and sources of zoonoses, zoonotic agents and food‐borne outbreaks in 2009 and 2010 specifically for the... by EFSA Panel on Animal Health and Welfare (AHAW)

“…These results, however, are not linked to further interpretation e.g. the potential reasons for any decrease or increase. It was recommended that the AHAW and BIOHAZ Panels should be consulted (e.g. as part of their annual mandate) before the Report is released to the public.…”
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Genetic diversity analysis of the SARS-CoV-2 virus: a literature review by Svetlana COLAC, Mariana ULINICI, Olga BURDUNIUC

“…The genome of the Omicron variant contains more than 30 mutations in the conserved domain of the Spike protein. …”
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