A broad-spectrum pneumococcal vaccine induces mucosal immunity and protects against lethal Streptococcus pneumoniae challenge by Fang-Feng Chiu, Ling-Ling Tu, Wangxue Chen, Hongyan Zhou, Bing-Sin Liu, Shih-Jen Liu, Chih-Hsiang Leng

“…Pneumococcal disease is a major threat to public health globally, impacting individuals across all age groups, particularly infants and elderly individuals. The use of current vaccines has led to unintended consequences, including serotype replacement, leading to a need for a new approach to combat pneumococcal disease. …”
Get full text

Inheritance of protein percentage in rice grain (review) by P. I. Kostylev, E. V. Krasnova, E. V. Dubina

“…The pericarp of rice grains contains proteins that increase immunity and protect the body from cardiovascular diseases and cancer, which has increased the relevance of this issue. …”
Get full text

Machine learning detection of heteroresistance in Escherichia coliResearch in context by Andrei Guliaev, Karin Hjort, Michele Rossi, Sofia Jonsson, Hervé Nicoloff, Lionel Guy, Dan I. Andersson

“…Genetic analysis of HR strains confirmed that HR is caused by an increased copy number of resistance genes via gene amplification or plasmid copy number increase. …”
Get full text

Classifying social position with social media behavioral data by Júlia Koltai, Zsófia Rakovics, Zoltán Kmetty, Kata Számel, Borbála Ungvári, Bendegúz Váradi, Ákos Huszár

“…When analyzing digital behavioral data, however large scale it is, information on the social position of the users is hardly available. In the current paper, we analyze a special dataset collected with a data donation technique, which contains information on both the social position and the observed digital behavior of participants, and which is representative for the internet user population of Hungary. …”
Get full text

DRUG UTILIZATION REVIEW OF FLUOROQUINOLONES AMONG THE OUT-PATIENTS IN A PUBLIC SECTOR HOSPITAL, PAKISTAN by Awais Arshaad, Shahzaib Sharafat, Ayesha Mustafa, Hamza Mahmood, Fatima Mustafa, Sonia Tariq, Ammara Asif

“… Background: The increase in antibiotic resistance is a challenging threat to the healthcare system. …”
Get full text

Effects of Microstructured and Anti-Inflammatory-Coated Cochlear Implant Electrodes on Fibrous Tissue Growth and Neuronal Survival by Lennart Fibranz, Wiebke Behrends, Katharina Wulf, Stefan Raggl, Lisa Kötter, Thomas Eickner, Soeren Schilp, Thomas Lenarz, Gerrit Paasche

“…However, due to the trauma caused by the insertion of the electrode and the subsequent formation of connective tissue, their clinical effectiveness varies. The aim of the current study was to achieve a long-term reduction in connective tissue growth and impedance by combining surface patterns on the electrode array with a poly-L-lactide coating containing 20% diclofenac. …”
Get full text

The comparative study of the corrosion stability of Zn-Ni-Co alloy coatings deposited from chloride and sulphate baths by Marija G. Riđošić, Jelena B. Bajat

“…On the other hand, [Co2+]/Ni2+] ion ratio showed a significant influence on corrosion behaviour of ternary alloy coatings, and this influence was more pronounced with alloys deposited from chloride baths. It was shown that increased corrosion protection of steel can be achieved by electrochemical deposition of ternary alloys that contained lower amount off the alloying elements, while the composition of the ternary alloy can be optimized by proper choice of the type and composition of the deposition bath.…”
Get full text

DEVELOPMENT OF A METHOD FOR THE INTERACTIVE CONSTRUCTION OF EXPLANATIONS IN INTELLIGENT INFORMATION SYSTEMS BASED ON THE PROBABILISTIC APPROACH by Serhii Chalyi, Volodymyr Leshchynskyi

“…Results: A model of the explanation pattern is proposed, which contains temporal regulations reflecting the sequence of user interaction with an intelligent system, which allows the formation of explanations based on a comparison of the actions of the current user and other well-known users. …”
Get full text

Coupling electrooxidation and UV for the treatment, and mineralization of amoxicillin and ibuprofen from aqueous solution: RSM parametric optimization and toxicity assessment by Solomon Ali Yimam, Shimelis Kebede Kassahun, Joon Wun Kang

“…The combination of EO with UV increased TOC removal efficiency for IBU, enhancing mineralization. …”
Get full text

Characterization of the solution heat-treated binary β-type Ti-Mo alloy for bio-implant applications by Netshia Mukhethwa, Phasha Maje, Ngobe Bongani, Olubambi Peter

“…As detected from XRD analysis, the intensity of the orthorhombic (α″) martensite phase increased with a decrease in heat-treated temperature. …”
Get full text

Telehealth coaching in older adults, behavior change, and impacts of the COVID-19 pandemic: analyses from The Brain Health Champion Study by Brittany McFeeley, Casey Nicastri, Taylor Krivanek, Kirk R. Daffner, Kirk R. Daffner, Seth A. Gale, Seth A. Gale

“…Study 1.0 participants indicated a decrease in cognitive activities since the start of COVID-19 restrictions, whereas those in Study 2.0 reported an increase in cognitive activities.DiscussionOur findings suggest that pandemic restrictions significantly impacted activities typically done outside the home (social and physical activity), while those feasibly achieved at home were less affected (Mediterranean diet adherence and cognitive activity). …”
Get full text

Breast milk: its components and special effects on newborns and infants by T. Voroncova, T. Konyk, M. Trokhymenko, Y. Mudryk

“…Transitional milk, which appears on days 4-14, increases the energy value due to increased lactose and fat content, promoting weight gain and microbiota development. …”
Get full text

A sustainable approach in pumpkin seed oil processing line: Recent advances in pumpkin seed oil and oil processing by-products by Guoqiang Zhang, Jingbo Guo, Jinying Guo

“…Pumpkin seed oil (PSO) has gained popularity worldwide for its nutritional profile and biological effects, significantly increasing its market demand and consumption. However, pumpkin seed oil cake (PSOC), as the secondary by-product from oil processing, contains high potential value and is scarcely utilised. …”
Get full text

Pre-sleep casein ingestion with probiotic strains improves anaerobic power and lower-body-specific strength and power performance in soccer players by Reza Sadeghi, Mohammad Hemmatinafar, Fereshteh Eftekhari, Babak Imanian, Negar Koureshfard

“…One-way analysis of covariance (ANCOVA) or Quade tests with a significance level of p < 0.05 was used to analyze the collected data.Result The current study’s findings indicated that APT-180°/s (ext) significantly increased in CAS (p = 0.008) and PRO+CAS (p = 0.003) compared to PLA. …”
Get full text

Polarization of T-helper 2 to 1 phenotype has arisen in rat asthmatic pulmonary tissue after intra-tracheal administration of bone marrow-derived c-Kit+ cells by Fatemeh Mir-ershadi, Mahdi Ahmadi, Reza Rahbarghazi, Hossein Heiran, Aref Delkhosh, Majid Khaksar, Rana Keyhanmanesh

“…Results: The results showed the successful homing of c-Kit+cells into the asthmatic niche. The significantly increased total number of leukocyte, eosinophil, neutrophil, and IL-4 mRNA levels, as well as decreased lymphocyte count, IL-10, IFN-γ mRNAs, and IL-4/IFN-γ ratio, were observed in asthmatic rats compared to C group (P<0.001). …”
Get full text

Extraction and Coordination Chemistry of Mo(Ⅵ)/U(Ⅵ) With Unilateral Derivatized Phenanthroline Amide Ligands by Tao-yuan XIU, Yue-kun LIU, Meng ZHANG, Yi HONG, Guo-an YE, Cai-shan JIAO, Li-yong YUAN, Wei-qun SHI

“…The experimental results indicate that the distribution ratios of Mo(Ⅵ) and U(Ⅵ) for the three ligands decrease with increasing acidity. This is mainly due to the absence of side chains on one side of the ligand, making the nitrogen atoms on the phenanthroline moiety more prone to protonation. …”
Get full text

Creation of polymer composites with mineral fillers by Mairamkul K. Chimchikova, Imilya A. Rysbaeva, Zhanbolot K. Aidaraliev, Akmarzhan Zh. Talgatbekova, Anarbek B. Mamytov

“… Introduction. Currently, the development of science and technology requires the creation of new polymer composites with high technical characteristics for various industries. …”
Get full text

EVALUTION OF MICROBIAL ACTIVITY IN ORGANIC SOLID FRACTION DURING COMPOSTING PROCESS TO BIOFERTILIZER USING COMPOSTING BIN METHODS by Aseel N. A., F. M. Hassan, N. H. Hyder

“… The current study aim to evaluating the composting in bins for organic fraction municipal solid waste and tracking the changes in physio-chemical and microbial characteristics such as Temperature, pH, C/N ratio and total viable count, total streptomyces, total coliform and pathogenic microorganisms as total Salmonella Shigella count. …”
Get full text

Influence of Moderate High-Pressure Homogenization on Quality of Bioactive Compounds of Functional Food Supplements by Encarna Aguayo, Martha Patricia Tarazona-Díaz, Ascensión Martínez-Sánchez, Antonio García-González

“…Current interest in health has led to an increase in demand for functional food supplements as well as in industry concern for maintaining the bioactive compounds of such foods via the application of new technologies. …”
Get full text

Multifunctional molecular hybrid for targeted colorectal cancer cells: Integrating doxorubicin, AS1411 aptamer, and T9/U4 ASO. by Kanpitcha Jiramitmongkon, Pichayanoot Rotkrua, Paisan Khanchaitit, Jiraporn Arunpanichlert, Boonchoy Soontornworajit

“…Additionally, examination of apoptotic pathways unveiled a marked decrease in Bcl-2 expression and a simultaneous increase in Bax expression in SW480 cells treated with Dox-loaded AS-T9/U4_MH, indicating its impact on promoting apoptosis. …”
Get full text