Spaciotemporal distribution characteristics of glacial lakes and the factors influencing the Southeast Tibetan Plateau from 1993 to 2023 by Yu Mingwei, Guo Yonggang, Zhang Jian, Li Feng, Su Libin, Qin Deshun

“…According to research findings, by 2023, southeastern Tibet is projected to contain 3,877 glacial lakes, encompassing an area of approximately 395.74 ± 22.72 km2. …”
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Prevalence of viral DNA in high-grade serous epithelial ovarian cancer and correlation with clinical outcomes. by Sharon E Robertson, Maya Yasukawa, Douglas C Marchion, Yin Xiong, Syeda Mahrukh Hussnain Naqvi, Tarik Gheit, Massimo Tommasino, Robert M Wenham, Anna R Giuliano, Johnathan M Lancaster, Mian M K Shahzad

“…<h4>Introduction</h4>Currently 11 infectious agents are classified as carcinogenic but the role of infectious agents on outcomes of epithelial ovarian cancer is largely unknown.…”
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Defining the Optimal Ranges of Tourist Visits in UNESCO World Heritage Caves with Rock Art: The Case of El Castillo and Covalanas (Cantabria, Spain) by Angel Fernandez-Cortes, Eduardo Palacio-Perez, Tamara Martin-Pozas, Soledad Cuezva, Roberto Ontañon, Javier Lario, Sergio Sanchez-Moral

“…These two caves are currently open to tourism and boast an exceptional archaeological heritage that includes magnificent examples of Palaeolithic cave art. …”
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Trusted Energy-Aware Hierarchical Routing (TEAHR) for Wireless Sensor Networks by Vikas, Charu Wahi, Bharat Bhushan Sagar, Manisha Manjul

“…Moreover, we explore the scalability of TEAHR across large networks as well as its performance in computationally constrained contexts. We have verified through our detailed investigation that the energy metrics used uniquely in TEAHR extend the life of the network while increasing data routing trust and trustworthiness. …”
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Amyloidogenic immunoglobulin light chains disturb contractile function and calcium transients in a human cardiac spheroid model of light chain (AL) amyloidosis by Mélanie Bézard, Jean-Sébastien Vartanian-Grimaldi, Julien Henri, Denisa Calin, Amira Zaroui, Mounira Kharoubi, Thibaud Damy, Onnik Agbulut, Ekaterini Kordeli

“…LC-treated hiPSC-CM cultures and LC-containing spheroids presented structural and functional defects including: (1) decreased levels and subcellular disorganization of sarcomeric protein alpha-actinin; (2) abnormal accumulation of calcium handling SERCA2a protein; (3) impaired contractility of spheroids and altered calcium transients. …”
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Evaluating Dietary Red Lentil Screenings on Performance, Antioxidant Status, Caecal Environment, and Intestinal Morphometric Features in Rabbits by Gianluca Pugliese, Caterina Losacco, Letizia Passantino, Giovanni Lentini, Maria M. Cavalluzzi, Michele Schiavitto, Simona Tarricone, Vito Laudadio, Vincenzo Tufarelli

“…Dietary RLS significantly decreased serum total cholesterol, LDL, and HDL, along with an enhancement of the overall serum antioxidant capacity. …”
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Identification, Evolution and Expression Analyses of the Hox Family in Procambarus clarkii by Xiaoyu WEI, Qian HU, Zemao GU, Yanhe LI

“…Homeobox genes are ubiquitous in eukaryotic genomes and can be transcribed into a homeodomain of approximately 60 amino acids. Hox genes are currently the most studied class of homeobox genes. …”
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Teucrium polium induces apoptosis in peripheral blood lymphocytes isolated from human chronic lymphocytic leukemia by Zarić Milan, Živković-Zarić Radica, Mitrović Marina, Nikolić Ivana, Čanović Petar, Milosavljević Zoran, Jovanović Danijela, Zelen Ivanka

“…The activation of apoptosis is one of the main molecular mechanisms responsible for anti-cancer activities of most of the currently studied potential anti-cancer agents, including natural compounds. …”
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Cooperative control method for multi-agent ground fracturing truck group based on offline reinforcement learning by RuYi Wang, HuiShen Jiao, YingCheng Tian, Yi Zhao, SiQi Wang, Ke Zhang, Bo Huang, QinRui Sun, DanDan Zhu

“…Abstract The increasing scale of unconventional oil and gas resource development has driven the demand for complex fracturing technologies. …”
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In Vitro Efficacy of PEI-Derived Lipopolymers in Silencing of Toxic Proteins in a Neuronal Model of Huntington’s Disease by Luis C. Morales, Luv Modi, Saba Abbasi Dezfouli, Amarnath Praphakar Rajendran, Remant Kc, Vaibhavi Kadam, Simonetta Sipione, Hasan Uludağ

“…<b>Methods:</b> This study aims to investigate the efficacy of siRNA-containing nano-engineered lipopolymers in selectively silencing the <i>HTT</i> expression in a neuronal model expressing a chimeric protein formed by the human mutated exon 1 of the <i>HTT</i> gene, tagged with GFP. …”
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Development of an easy non‐destructive particle isolation protocol for quality control of red blood cell concentrates by Marine Ghodsi, Anne‐Sophie Cloos, Anaïs Lotens, Marine De Bueger, Patrick Van Der Smissen, Patrick Henriet, Nicolas Cellier, Christophe E. Pierreux, Tomé Najdovski, Donatienne Tyteca

“…Nevertheless, there is currently no standardized isolation protocol. In a previous publication, we developed a reproducible ultracentrifugation‐based protocol (20,000 × g protocol) that allows to classify red blood cell concentrates into three cohorts according to their vesiculation level. …”
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Internet and telephone intervention to support patients discontinuing long-term antidepressants in primary care: the REDUCE research programme including RCT by Tony Kendrick, Beth Stuart, Hannah Bowers, Mahboobeh Haji Sadeghi, Helen Page, Christopher Dowrick, Michael Moore, Mark Gabbay, Geraldine Leydon, Guiqing Lily Yao, Shihua Zhu, Paul Little, Gareth Griffiths, Glyn Lewis, Carl May, Joanna Moncrieff, Chris F Johnson, Una Macleod, Simon Gilbody, Rachel Dewar-Haggart, Samantha Williams, Wendy O’Brien, Riya Tiwari, Catherine Woods, Tasneem Patel, Naila Khan, Emma Maund, Nadja van Ginneken, Amy Din, Claire Reidy, Rebecca Lucier, Bryan Palmer, Taeko Becque, Yumna Masood, Natalie Thompson, Ellen van Leeuwen, Marta Glowacka, Adam WA Geraghty

“…Background There is significant concern about increasing long-term antidepressant use in Western countries, much of which is not evidence-based. …”
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The involvement of the synaptic vesicle cycle in homocysteine induced neurotoxicity in vitro and in vivo by Meng Wang, Xiaoshan Liang, Keqing Jin, Yinyue Liu, Suhui Luo, Qiang Zhang, Xuan Wang, Zhiping Dong, Xumei zhang

“…However, there is currently a lack of comprehensive understanding regarding the molecular mechanisms underlying Hcy-induced neurotoxicity. …”
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Preparation, mechanical, and thermal properties of CrNbO4: A novel dual-functional scale to protect RHEAs from oxidation and thermal attack by Shuang Zhang, Jian Zhang, Xiaohui Wang, Huimin Xiang, Cheng Fang, Wei Xie, Yanchun Zhou

“…Interestingly, the room temperature thermal conductivity of CrNbO4 is 1.09 W·m−1·K−1 and decreases to 0.45 W·m−1·K−1 at 1473 K, which is lower than that of most of the currently well-known thermal insulation materials. …”
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Effects of wetting events on mass timber surface microbial communities and VOC emissions: implications for building operation and occupant well-being by Gwynne Á. Mhuireach, Susan Collins, Leslie Dietz, Patrick Finn Horve, Aurélie Laguerre, Dale Northcutt, Jason Stenson, Kevin Van Den Wymelenberg, Elliott Gall, Mark Fretz

“…IntroductionHumans have used wood as a construction material throughout history. Currently, mass timber products, such as cross-laminated timber (CLT), are becoming more popular as a structural material, since they are renewable and have a lower carbon footprint than concrete or steel. …”
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Expression, prognosis and preliminary investigation of the mechanism of action of ACTR6, a member of the ARPs gene family, in hepatocellular carcinoma by Jing Wang, Meng Song, Jinming Tang, Haoran Yue, Xiaoyang Guo, Zhan Chen, Xiaolan Shen, Mingbo Cao, Mingbo Cao

“…It is critical to investigate new biomarkers and prognostic variables because there are currently no early diagnostic indicators. Actin-related proteins (ARPs) are involved in transcriptional regulation, chromatin remodeling, and DNA repair—all processes that have been connected to the development of cancer. …”
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Nanostructured Strategies for Melanoma Treatment—Part I: Design and Optimization of Curcumin-Loaded Micelles for Enhanced Anticancer Activity by Valentina Paganini, Andrea Cesari, Silvia Tampucci, Patrizia Chetoni, Susi Burgalassi, Michele Lai, Giulia Sciandrone, Silvia Pizzimenti, Fabio Bellina, Daniela Monti

“…<b>Background/Objectives</b>: Melanoma is a pathology that affects a large part of the population, and the currently available therapies have many limitations, including the selective targeting of the site of action. …”
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Development and evaluation of optimized PCR and indirect ELISA for the detection of Morganella morganii in dairy cows by Meihua Zhang, Jiayi Li, Jianfeng Xue, Huiling Xu, Muzi Li, Yibo Xia, Changxi Qi, Pu Zhang, Yongxia Liu, Jianzhu Liu

“…IntroductionMorganella morganii (M. morganii) is a Gram-negative opportunistic pathogen, whose increasing virulence and antibiotic resistance negatively impact dairy cow health and productivity, raising concerns in livestock health management. …”
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NECROSIS AS A COMPLICATION OF LOCAL ANESTHESIA IN DENTISTRY by V.V. Lepsky, C. V. Osik

“…However, as a rule, most of the groups of painkillers contain vasoconstrictors of the cartridge, such as adrenaline hydrochloride, noradrenaline, although the last one is currently banned for use because of the complications that it can cause. …”
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Optimized biosynthesis and performance enhancement of γ-PGA from Bacillus licheniformis: a study on wettability, microstructure, and environmental performance by Mingming Cheng, Shuoshi Zhang, Jianbo Gao, Wenqing Liu, Gang Zhou, Tao Sui, Daoquan Cheng, Cheng Wang, Xiangchuan Wang, Xiaoyan Li, Yuxi Li

“…Infrared spectroscopy analysis showed that the purified product contained typical functional groups of γ-PGA. Changes in the contact angle of γ-PGA solution with coal dust over time demonstrated that brown coal was wetted extremely quickly, with the largest change in contact angle; within 5 min of dropping the fermentation liquid, the contact angle sharply decreased from 69° to 0°, completely wetting the brown coal. …”
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