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  1. 1681
  2. 1682

    A Comparison of the 𝜶2/3/5 Selective Positive Allosteric Modulators L-838,417 and TPA023 in Preclinical Models of Inflammatory and Neuropathic Pain by Sarah Nickolls, Hannah Mace, Rebecca Fish, Michelle Edye, Rachel Gurrell, Magnus Ivarsson, Tom Pitcher, Sachi Tanimoto-Mori, Denise Richardson, Catherine Sweatman, Janet Nicholson, Cameron Ward, John Jinks, Christine Bell, Kimberly Young, Huw Rees, Andrew Moss, Ross Kinloch, Gordon McMurray

    Published 2011-01-01
    “…GABAA receptors containing α2/3 subunits are current targets in the battle to develop new pain medications, as they are expressed in the spinal cord where increasing inhibitory drive should result in analgesia. …”
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    Article
  3. 1683

    High dynamic range capillary electrophoresis method for sensitive detection of low-frequency driver mutations by Nobue Tamamura, Yoshihiko Hagiwara, Hirokazu Kato, Yusuke Ono, Kenji Takahashi, Kazuya Koyama, Hiroki Sato, Tetsuhiro Okada, Hidemasa Kawabata, Yu Ohtaki, Chiho Maeda, Miyuki Mori, Shin-ichi Chiba, Mishie Tanino, Kenzui Taniue, Takashi Anazawa, Ryoji Inaba, Yusuke Mizukami

    Published 2025-07-01
    “…Abstract Cancer genomics aims to personalize treatments by identifying genetic abnormalities in cancer cells. However, current analytical techniques face limitations in simplicity and cost-effectiveness. …”
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  4. 1684

    BK channel activity in skin fibroblasts from patients with neurological disorder by Ria L. Dinsdale, Thomas R. Middendorf, Deborah Disilvestre, David Adams, William Gahl, Ellen F. Macnamara, Lynne Wolfe, Camilo Toro, Cynthia J. Tifft, Andrea L. Meredith

    Published 2025-12-01
    “…Fibroblasts from the individual harboring the E656A variant showed decreases in the number of BK channels detected and E656A-containing transcripts compared to controls. …”
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  5. 1685

    Pharmacological correction of hepatotoxicity induced by anti-tuberculosis drugs by D. S. Sukhanov, E. V. Timofeev, Y. S. Alekseeva, K. A. Nagornova

    Published 2023-04-01
    “…Hepatoprotective drugs of various origin and chemical composition are used for the correction and prevention of drug-induced liver injury. Currently, preparations of plant origin (from milk thistle, licorice, soy), animal origin, preparations of bile acids, and some others are isolated. …”
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  6. 1686

    Long-term dynamics of forests with Pinus sibirica in the upper reaches of the River Kolva (Northern Pre-Urals, Russia) from 1938 to 2023 by Alexei A. Aleinikov, Vadim E. Aleksutin, Foma K. Vozmitel, Alexey N. Gunya

    Published 2024-08-01
    “…Due to the exceptionally slow regeneration following fires and logging activities, Pinus sibirica is absent in the forests formed over the studied period. The current federal legal restrictions prove ineffective as they target the preservation of forest stands containing over 30% of Pinus sibirica, while the majority of forests in the study area contain less proportion of this species. …”
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  7. 1687

    Development of a composite material based on a processed product of agricultural crop by Zura Yessimsiitova, Murat Toktar, Alibek Mutushev, Aizhan Konysbayeva, Gulmira Yeltay, Aliya Bagybekkyzy, Akmaral Kydyrkhanova, Damira Yussayeva

    Published 2024-10-01
    “…Anthropogenic influence on the environment contributes to an increase in the content of heavy metals in soils. This is facilitated by the developed industrial sector, high population density and large-scale growth of urban areas. …”
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  8. 1688
  9. 1689

    Use of nicotine products — a cross-sectional survey of adolescents in Poland by Piotr Korczyński, Stanisław Surma, Agnieszka Jankowska-Zduńczyk, Sebastian Szmit, Piotr Wierzbiński, Janusz Sytnik-Czetwertyński, Krzysztof J. Filipiak

    Published 2025-06-01
    “…INTRODUCTION: Cigarette smoking has been a significant health problem in the world for decades. Currently, new forms of smoking are becoming increasingly popular — e-cigarettes and tobacco heating systems (HnB, heat-not-burn), whose impact on the human body is not indifferent. …”
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  10. 1690

    Research hotspots and trends in the application of diffusion tensor imaging in ischemic stroke: a bibliometric analysis (2003–2024) by Xu Chen, Xu Chen, Meifang Liu, Xiaolin Yang, Mengqi Yue, Haocheng Yu, Haiqiang Wang, Zirong Wang, Jing Shi, Jing Shi, Yong Qiu

    Published 2025-06-01
    “…The number of DTI-related publications in IS has been increasing year by year. The three primary publishing nations are the United States, China, and the United Kingdom. …”
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  11. 1691

    Gene Editing Anxiety by Angelo Osofsky

    Published 2025-05-01
    “…Health and Genetic Risks of Germline Editing Editing the human germline to prevent psychiatric disorders poses serious health risks to individuals. Currently, scientists warn that genetically altering the human genome can result in off-target mutations that increase the risk of disease. …”
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  12. 1692

    Highly sensitive multiplex PCR for convenient quantification and differentiation of canine Oomycota pathogens: Pythium insidiosum, Lagenidium giganteum f. caninum, and Paralagenidi... by Asfiha Tarannum, Subarna Barua, Leonel Mendoza, Raquel Vilela, Priscilla Barger, Terri Hathcock, Amelia White, Kelly Chenoweth, Chengming Wang

    Published 2025-06-01
    “…ABSTRACT Oomycota mammalian pathogens, including Pythium (P.) insidiosum, Lagenidium (L.) giganteum f. caninum, and Paralagenidium (Para.) karlingii, are increasingly recognized as causes of life-threatening infections in dogs, with diagnosis complicated by their clinical and phenotypic resemblance to fungal pathogens. …”
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  13. 1693

    Mycochemistry, antioxidant, anticancer activity, and molecular docking of compounds of F12 of ethyl acetate extract of Astraeus asiaticus with BcL2 and Caspase 3 by Swapan Kumar Ghosh, Koushik Pandey, Madhuparna Ghosh, Pradip Kumar Sur

    Published 2025-02-01
    “…Abstract Globally the current research is going for cancer disease management by different strategies as frequency and severity of this disease are increasing day by day. …”
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  14. 1694

    Combined single- and dual-energy CT workflow for dose calculation in radiotherapy by Hella Sand, Jens Edmund, Ane Appelt, Patrick Wohlfahrt, Vicki Trier Taasti, Laurids Østergaard Poulsen, Jimmi Søndergaard, Martin Skovmos Nielsen

    Published 2025-08-01
    “…Background and purpose: Dual-energy computed tomography (DECT) is increasingly used in radiotherapy delineation due to its enhanced soft tissue contrast. …”
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  15. 1695

    Research progress on the control of reactive elements in remelted ingots during the electroslag remelting process by Shengchao DUAN, Lifeng ZHANG

    Published 2025-05-01
    “…Additionally, the physical parameters of the slag system play a crucial role in determining the surface quality and solidification characteristics of the ingots. Current research on the physical parameters of remelting slag systems containing TiO2, SiO2, B2O3, and rare earth oxides has primarily focused on viscosity and crystallization behavior. …”
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  16. 1696

    Assessment of Nurse's Health Promotion of Their Lifestyles at Al-Kut City Hospitals, Iraq by Ammar A. Okab

    Published 2024-02-01
    “…Poor lifestyle choices lead to chronic diseases or even death. It increases healthcare costs in a time of economic downsizing. …”
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  17. 1697

    Features of “Inverted” Educational Resources for Distance Learning of Pupils by D. A. Barkhatova, A. L. Simonova, P. S. Lomasko, L. B. Khegay

    Published 2021-08-01
    “…The main idea behind the development of such tools is that the “inverted” learning resources, on the one hand, implement a non-linear approach to the implementation of learning activities in accordance with the individual characteristics of a particular student (the current level of training, knowledge gaps, specific interests and difficulties), with the other - they create conditions for the initial systematization and complex internalization of the acquired knowledge and methods of action, contain a “cognitive challenge” aimed at increasing educational motivation through the implementation of mechanisms of formative self-control at the initial stage. …”
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  18. 1698

    Using the Smath Computer Package in School Mathematics Lessons by Valery F. Ochkov, Inna E. Vasileva, Yuliya V. Shatskikh

    Published 2025-03-01
    “…Numerous examples of the graphical capabilities of the package implemented directly by students are given. This significantly increases the awareness and clarity of perception of the material by schoolchildren. …”
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  19. 1699

    Shaping the future of nanotechnology: a perspective on education, dissemination and ethics by Jordi Díaz-Marcos, Jordi Díaz-Marcos, Joan Mendoza Gonzálvez

    Published 2025-05-01
    “…We analyze the available tools and highlight the current state of nanodissemination through a comprehensive review of mature and successful dissemination initiatives in nanosciences and nanotechnologies. …”
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  20. 1700

    A novel proof of concept approach towards generating reference microplastic particles by Simon D.J. Oster, Paul E. Bräumer, Daniel Wagner, Max Rösch, Martina Fried, Vinay K.B. Narayana, Eva Hausinger, Helena Metko, Eva C. Vizsolyi, Matthias Schott, Christian Laforsch, Martin G.J. Löder

    Published 2024-12-01
    “…Abstract For almost two decades now, scientists have increasingly focused on the occurrence of microplastic particles (MPs) in the environment and their impact on environmental and human health. …”
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