HNF-1β alleviates podocyte injury in lupus nephritis by maintaining endoplasmic reticulum homeostasis by Jie Yu, Bing Guo, Fan Zhang, Miao Liu, Ying Xie, Hui-mei Zou, Yuan-yuan Ruan, Xiao-min An, Pei-lei Chen, Ying-qin Luo, Ming-jun Shi, Li-fen Xu

“…Objective The current study aims to elucidate the critical function of hepatocyte nuclear factor 1-beta (HNF1-β) in lupus nephritis (LN) by investigating its modulation of the Derlin-1/valosin-containing protein (VCP)/VCP-interacting membrane selenoprotein (VIMP) complex, endoplasmic reticulum (ER) stress and podocyte apoptosis.Methods In vitro and in vivo models of LN were established using glomerular podocytes treated with LN serum and MRL/lpr mice, respectively. …”
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Telehealth coaching in older adults, behavior change, and impacts of the COVID-19 pandemic: analyses from The Brain Health Champion Study by Brittany McFeeley, Casey Nicastri, Taylor Krivanek, Kirk R. Daffner, Kirk R. Daffner, Seth A. Gale, Seth A. Gale

“…IntroductionWhen COVID-19 containment strategies were imposed in March 2020, we became interested in how these restrictions might interfere with brain-healthy behaviors of older adults who were either actively participating in or who had recently completed our telehealth behavior change intervention. …”
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Pramipexole in addition to mood stabilisers for treatment-resistant bipolar depression: the PAX-BD randomised double-blind placebo-controlled trial by Hamish McAllister-Williams, Nicola Goudie, Lumbini Azim, Victoria Bartle, Michael Berger, Chrissie Butcher, Thomas Chadwick, Emily Clare, Paul Courtney, Lyndsey Dixon, Nichola Duffelen, Tony Fouweather, William Gann, John Geddes, Sumeet Gupta, Beth Hall, Timea Helter, Paul Hindmarch, Eva-Maria Holstein, Ward Lawrence, Phil Mawson, Iain McKinnon, Adam Milne, Aisling Molloy, Abigail Moore, Richard Morriss, Anisha Nakulan, Judit Simon, Daniel Smith, Bryony Stokes-Crossley, Paul Stokes, Andrew Swain, Zoë Walmsley, Christopher Weetman, Allan H Young, Stuart Watson

“…Background There are limited options currently recommended in National Institute for Health and Care Excellence guidelines for the treatment of bipolar depression. …”
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Changes in the Separation Properties of Aged PVDF Ultrafiltration Membranes During Long-Term Treatment of Car Wash Wastewater by Wirginia Tomczak, Marek Gryta, Piotr Woźniak, Monika Daniluk

“…Indeed, the aged membranes were characterised by the increased porosity. However, it is important to note that membranes aging had no significant impact on the permeate quality during the UF process of synthetic CWW. …”
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Green Synthesis of Cr2O3 Nanoparticles for Enhanced OTFT Performance compared to Pentacene-Based Organic Thin Film Transistor Devices by Arun Singh Rathod, Abhilasha Mishra, Waseem Ahmad, Sanjay Kumar

“…As per the electrical properties, chromium oxide (Cr2O3) nanoparticles are categorized as semiconductors and could be used as an alternative to conventional polymer and small molecule-based semiconductor materials used in organic thin film transistors (OTFTs). In the current investigation, the performance of two bottom gate bottom contact (BGBC) OTFTs comprising pentacene and chromium oxide (Cr2O3) nanoparticles as semiconductor material, respectively, was analyzed comparatively. …”
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Optimizing MEMS inertial switches for efficient event-based environmental interaction: motivation, approaches, and purposes by Lyuyan Wang, Jiahao Zhao, Zheng You

“…Abstract The rapid growth of the Internet of Things (IoT) and embodied intelligence has increased the demand for sensor nodes that conserve energy and reduce data transmission, especially in resource-limited applications that rely heavily on sensors. …”
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The Influence of Pulsed Electron Beam Processing on the Quality of Working Surfaces of Titanium Alloy Products by Undrakh Mishigdorzhiyn, Aleksey Pyatykh, Andrey Savilov, Nikolay Ulakhanov, Ivan Galetsky, Kirill Demin, Alexander Tikhonov, Maxim Vorobyov, Elizaveta Petrikova, Shunqi Mei

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Influence of calcium carbonate reinforcement on mechanical properties and sustainability of hdpe-recycled plastic composites for industrial applications by Yassin Ahmed, Mohammed Ahmad

“…Currently, the demand for sustainable materials has led to an interest in polymer composites filled with mineral fillers and recycled materials. …”
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“Investigating the Synergistic Effects of Curcumin on the Oxidative Stability of Flaxseed (Linum usitatissimum) Oil: A Kinetic Study” by Mahya Azari, Mahsan Karimi, Seyed Mohammad Mazloomi, Mohammad-Taghi Golmakani, Azam Abbasi

“…In the current study, the change in entropy (ΔS) decreases to 1000 ppm curcumin which explains the slower rate of oxidation in this case. …”
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Towards meeting the food needs of urban households in sub-Saharan Africa: an analysis of formal sector employees’ participation in agricultural production in urban Wa, Ghana by Peter Dery Bolang, Issah Baddianaah, Issaka Kanton Osumanu

“…The study recommends that the Ministry of Food and Agriculture (MoFA) should encourage and support formal sector employees to embrace at least one, but preferably both, of Ghana’s current agricultural sector policies: Planting for Food and Jobs (PFJ), Rearing for Food and Jobs (RFJ) and Planting for Export and Rural Development (PERD) for increased and sustained food production in Ghana’s urban communities. …”
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Bicomponent ZnO-Ag janus nanoparticles with high antitumor activity <I>in vitro</I> by O. V. Bakina, V. R. Zhou, M. I. Lerner

“…The high antitumor activity of nanoparticles with a minimum silver content can be explained by a decrease in the size of silver fragments from 46 nm to 23 nm and a decrease in the average particle size from 92 nm to 54 nm. …”
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Structural and hydraulic changes in grape shoot xylem under different root zone volumes by 伟晴 冯, You-Mei Li, Chen Zhou, Zhao-Sen Xie

“…The results indicate that a decrease in container volume leads to a decrease in shoot growth and xylem vessel size. …”
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Studying and Characterization of Coating of Zein–CaSiO3 Composite on Polyetheretherketone Implant Material by Sama Abdulrazzaq, Thekra Ismael Hamad

“…Each group was characterized by atomic force microscopy, field emission scanning electron microscope, Fourier-transform infrared spectroscopy, water contact angle, and adhesion strength. The lowest water contact angle was obtained for Group 1: 10% wt and 90% wt were (26.64° and 27.13°, respectively), and increasing amounts of zein in comparison to quantities of CaSiO3 resulted in increased adhesion strength of the composite material to the substrate. …”
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Extraction and Coordination Chemistry of Mo(Ⅵ)/U(Ⅵ) With Unilateral Derivatized Phenanthroline Amide Ligands by Tao-yuan XIU, Yue-kun LIU, Meng ZHANG, Yi HONG, Guo-an YE, Cai-shan JIAO, Li-yong YUAN, Wei-qun SHI

“…Medical radioactive isotopes play a very important role in disease diagnosis and treatment, with 99Tcm drugs being widely used in disease diagnosis. 99Tcm is primarily obtained from its parent nuclide, 99Mo, through a 99Mo/99Tcm generator. Currently, the main methods of producing 99Mo include reactor production, accelerator-based production, and neutron generator production. …”
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Creation of polymer composites with mineral fillers by Mairamkul K. Chimchikova, Imilya A. Rysbaeva, Zhanbolot K. Aidaraliev, Akmarzhan Zh. Talgatbekova, Anarbek B. Mamytov

“… Introduction. Currently, the development of science and technology requires the creation of new polymer composites with high technical characteristics for various industries. …”
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Microstructure and electrochemical corrosion behaviour of API 5L X90 pipeline steel in a simulated soil environment by Mahdi Yeganeh, Mostafa Eskandari, Hasan Mousavi

“…Potentiodynamic polarization tests indicated an absence of passivation, accompanied by a decrease in corrosion current density and a shift in corrosion potential toward the cathodic direction during immersion. …”
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Inositol Pyrophosphate Profiling of Two HCT116 Cell Lines Uncovers Variation in InsP8 Levels. by Chunfang Gu, Miranda S C Wilson, Henning J Jessen, Adolfo Saiardi, Stephen B Shears

“…The HCT116 cell line, which has a pseudo-diploid karotype, is a popular model in the fields of cancer cell biology, intestinal immunity, and inflammation. In the current study, we describe two batches of diverged HCT116 cells, which we designate as HCT116NIH and HCT116UCL. …”
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Three-step fabrication of TiO2CdS spheres on SiO2 supports for enhanced hydrogen evolution performance by Zhengyou Li, Alexander V. Soldatov, Aslam Hossain

“…The overpotential exhibited a notable decrease from 793 mV to 264 mV at a current density of 10 mA/cm², demonstrating the improved electrocatalytic efficiency as CdS concentration increased. …”
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Transuterine relocation of pregnant uterine horn segment in an exploratory rat model with implications for tubal ectopic pregnancy by Cara Buskmiller, Christina Camilleri, Stephen Sammut

“…Abstract Ectopic pregnancy affects ~ 2% of pregnancies annually in the United States, with no current treatments allowing for the continuation of the pregnancy. …”
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Minimizing unnecessary proBNP blood tests: an evaluation of a pop-up form implementation in general practice by Morvarid Sophia Esmaeilzadeh, Anna Elise Engell, Henrik Løvendahl Jørgensen, Bent Struer Lind

“…In this group, the median proBNP level increased from 12.1 pmol/L before the intervention to 13.5 pmol/L after the intervention (p < 0.0001).Conclusions This study demonstrates a significant decrease in the number of proBNP requests from general practitioners in the Capital Region of Denmark after the introduction of a pop-up form in the requisition system containing the current guidelines.…”
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