Blood-based biomarkers in mild behavioral impairment: an updated overview by Efthalia Angelopoulou, Xenia Androni, Chiara Villa, Alexandros Hatzimanolis, Nikolaos Scarmeas, Sokratis Papageorgiou

“…A growing number of studies have recently begun to explore the relationship between MBI and several blood-based biomarkers associated with Alzheimer’s disease (AD) pathology, neurodegeneration, as well as systemic metabolic and inflammatory dysregulation. In this context, MBI has been associated with lower plasma Aβ42/Αβ40 ratio, higher plasma phosphorylated tau at threonine 181 (p-tau181), increased neurofilament light chain (NfL) levels, as well as disturbances in metabolic markers, including homocysteine, insulin and ferritin, suggesting a multifaceted neurobiological basis for this syndrome. …”
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Inside CKD: Cost-Effectiveness of Multinational Screening for CKD by Navdeep Tangri, Kook-Hwan Oh, Jason C.J. Choo, Michel Jadoul, Johan Ärnlöv, Marcelo Costa Batista, Christian F. Christiansen, Gil Chernin, Lise Retat, Joshua Card-Gowers, Timothy Coker, Salvatore Barone, Stephen Nolan, Juan Jose Garcia Sanchez

“…Screening general populations aged ≥ 45 years increased projected CKD diagnosis rates per 100,000 persons eligible for screening from 459 by current practice to 7475 patients using 2 eGFR only, or 14,392 using 2 eGFR and 1 UACR. …”
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Cell Therapy in Ischemic Heart Disease: Interventions That Modulate Cardiac Regeneration by Maximiliano I. Schaun, Bruna Eibel, Melissa Kristocheck, Grasiele Sausen, Luana Machado, Andreia Koche, Melissa M. Markoski

“…The incidence of severe ischemic heart disease caused by coronary obstruction has progressively increased. Alternative forms of treatment have been studied in an attempt to regenerate myocardial tissue, induce angiogenesis, and improve clinical conditions. …”
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Neutrophil-to-Lymphocyte ratio as surrogate for JAK2V617F suppression and event-free survival in polycythemia vera by Tiziano Barbui, Arianna Ghirardi, Victoria Empson, Francesca Fenili, Giuseppe Gaetano Loscocco, Annalisa Condorelli, Alessandra Iurlo, Daniele Cattaneo, Elena Rossi, Valerio De Stefano, Paola Guglielmelli, Christoph Klade, Heinz Gisslinger, Alessandro Rambaldi, Joseph M. Scandura, Alessandro Maria Vannucchi

“…Abstract Chronic systemic inflammation is a key driver of polycythemia vera (PV) progression, but the immunomodulatory effects of current treatments remain poorly defined. The neutrophil-to-lymphocyte ratio (NLR) is an accessible biomarker of systemic inflammation proven in other contexts, but its role in monitoring PV disease activity has not been established. …”
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Gender differences in use of cigarette and non-cigarette tobacco products among adolescents aged 13–15 years in 20 African countries by Israel T. Agaku, Rose Sulentic, Adriana Dragicevic, Gibril Njie, Candace K. Jones, Satomi Odani, Tina Tsafa, Joy Gwar, Constantine I. Vardavas, Olalekan Ayo-Yusuf

“…Among girls, higher levels of reported exposure to tobacco advertisement were positively associated with shisha smoking whereas perceived tobacco harm was inversely associated with current cigarette and shisha smoking. Among boys, perceived social acceptability of smoking at parties was associated with an increased likelihood of cigarette smoking (APR=2.27; 95% Cl: 1.20–4.30). …”
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Structural and Spatial-Functional Changes in the Development of Enterprises in Ukraine by Ivan Burtnyak, Oleksandr Kusnir, Roman Kashevskyi

“…The first approach is confirmed by observations of periodic increases in demand, especially for agricultural land. …”
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The Immune Environment in Colorectal Adenoma: A Systematic Review by Ugne Silinskaite, Jurate Valciukiene, Matas Jakubauskas, Tomas Poskus

“…<b>Methods:</b> In this systematic review, we aim to provide a thorough analysis of the current research examining the immune infiltration patterns in sporadic colorectal adenoma tissues in the context of immune cell-based, cytokine-based, and other immunological factor-related changes along the conventional adenoma–carcinoma sequence. …”
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Data Modeling of Impact of Green-Oriented Transportation Planning and Management Measures on the Economic Development of Small- and Medium-Sized Cities by Yuan Lu, Jinyan Shao, Yifeng Yao

“…With the rapid growth of urbanization and motorization in China in recent years, the demand for transportation in people’s work and daily lives has increased. In this context, a number of issues such as urban traffic congestion, energy consumption, and environmental pollution have become increasingly severe. …”
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Transformation of the Regional Policy of Russia and China under the Conditions of Unequal Development of Regions (1980-2020): a Comparative Historical Study by S. B. Makeeva

“…The purpose of this article is a comparative and consideration of the evolution of the regional policy of Russia and China in the context of the increasing unevenness and disproportionality of the internal regional development of the two countries in the modern period of history. …”
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Analysis of the distribution of digital tools in the activities of russian enterprises by Melnikov Alexander, Kalabina Elena

“…The information base was statistical data on the use of digital technologies by enterprises, as well as research on trends and management methods in the context of digital transformation. The result of the work was the formation of an assessment of the current state of the spread of digital technologies in the activities of enterprises in the Russian Federation. …”
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Crosstalk between ferroptosis and innate immune in diabetic kidney disease: mechanisms and therapeutic implications by Jinyang Wang, Haonan Shi, Ye Yang, Xueli Gong

“…Diabetic kidney disease (DKD) is a prevalent complication of diabetes mellitus (DM), and its incidence is increasing alongside the number of diabetes cases. Effective treatment and long-term management of DKD present significant challenges; thus, a deeper understanding of its pathogenesis is essential to address this issue. …”
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Horticultural performance and QTL mapping of snap bean (Phaseolus vulgaris L.) populations with organic and conventional breeding histories by Hayley E. P. Richardson, Ryan M. King, Joel Davis, James R. Myers

“…IntroductionImproving crop cultivars for use on organic farms is pertinent, as current elite germplasm is less resilient within the more variable context of organic farm environments. …”
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Next generation High-Mobility 2D chalcogenides TFT for display backplane by Prashant Bisht, Junoh Shim, Jooon Oh, Jieun Lee, Hoseong Shin, Hyeonho Jeong, Jimin Kim, Junho Lee, Hyuk-Jun Kwon, Sunkook Kim

“…In this context, 2D chalcogenides have emerged as promising candidates for thin-film transistors (TFTs) in display backplanes, offering advantages such as high mobility, low leakage current, mechanical robustness, and transparency. …”
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Re-use of Building Products in the Netherlands by Loriane Icibaci

“…Although improvements can be made in each one of these relations, it is relevant to understand how they can affect the system combined. For instance, increase building disassembly does not guarantee increase demand for used products in the future. …”
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Leveraging green innovation from big data analytics: Examining the role of resource orchestration and green dynamic capabilities by Masood Nawaz Kalyar, Agata Pierscieniak, Muhammad Shafique

“…PURPOSE: The notion of big data analytics (BDA) has received increased attention from both researchers and managers. …”
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Special features for functionalization of carbon nanotubes nanopowders by N. O. Oliinyk, G. D. Ilnytska, G. A. Bazaliy, I. M. Zaitseva, M. A. Marinich, O. M. Sizonenko, A. S. Torpakov

“…In order to create new composite materials that contain CNT powders as a filler, it is necessary to achieve functionalization of powder surface. …”
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Warming Yang,Promoting Blood Circulation and Inducing Diuresis in the treatment of diabetic nephropathy:a meta-analysis by WANG Lan, WANG Xiao-qin

“…Objective To evaluate the efficacy and safety of ’Warming Yang,Promoting Blood Circulation and Inducing Diuresis’ in the treatment of diabetic nephropathy(DN).Methods The used electronic databases contained foreign databases such as PubMed,EMBASE,Cochrane Library,and Chinese databases such as CNKI,SinoMed,Wanfang Data,CQVIP.The clinical data of "Warming Yang,Promoting Blood Circulation and Inducing Diuresis" in treatment of DN were collected comprehensively.The literature retrieval ended on April 1,2016,and the meta analysis of appropriate literature was processed by RevMan 5.3 software.Results The cases of randomized controlled trials totaled16 and the cases of DN patients totaled 1 107.The results of Meta analysis showed that compared to western medicine control group,the experimental group of integrated traditional Chinese medicine and western medicine,based on "Warming Yang and Benefiting Qi,Promoting Blood Circulation and Inducing Diuresis",perfonned better in the significant efficiency and total efficiency of the treatment of DN(RR=1.97,95%CI 1.50~2.59,Z = 4.86,P<0.01;RR=1.48,95%CI 1.35~1.62,Z=8.58,P<0.01),in the decrease of the serum creatinine(MD=-32.33,95%CI-58.20~-6.47,Z =2.45,P= 0.01),in the increase of high density lipoprotein(MD= 0.16,95%CI 0.09~0.23,Z =4.33,P<0.01),in the decrease of cholesterol,triglyceride,low density lipoprotein(MD=-0.82,95%CI 1.28~-0.36,Z = 3.49,P = 0.0005;MD=-0.40,95%CI-0.53~-0.26,Z=5.95,P<0.01;MD=-0.49,95%CI-0.76~-0.21,Z=3.46,P = 0.000 5),in the decrease of urinary protein(MD=-0.46,95%I-0.61~-0.31,Z=6.01,P<0.01),in the control of fasting blood glucose(MD=-0.34,95%CI-0.57~-0.12,Z = 3.00,P = 0.003),and performed the same in the decrease of the levels of tumor necrosis factor alpha(P= 0.33).Conclusions The current limited evidence suggests that the efficacy and safety of integrated traditional Chinese medicine and western medicine in the treatment of DN is better than the traditional protocols alone.…”
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An open-label phase I comparator-controlled clinical trial to assess tolerability and pharmacokinetics of IHL-675 A a fixed dose combination of cannabidiol plus hydroxychloroquine... by George Williams Mbogo, Pia Kroner, Rosemarie Walsh, Jonathan Newchurch, Mark Robert Bleackley

“…IHL-675 A is Incannex Healthcare Pty Ltd.’s proprietary product formulated using UniGel™ technology consisting of a solid, film coated HCQ tablet contained within a CBD-oil solution gel cap. Each IHL-675 A gel cap contains 75 mg of CBD and 100 mg HCQ. …”
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Quality failures in Energy- saving renovation projects in Northern China by Yuting Qi

“…In China, the proportion of building energy consumption has increased rapidly year-by-year (Zheng et al. 2019). …”
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Non-linear surges and extreme wind-waves in Port Phillip Bay under existing and future mean sea levels by Huy Quang Tran, Huy Quang Tran, Franklin Ayala Cruz, Jak McCarroll, Alexander Babanin

“…Modelled data were extracted from 24 different stations in the bay at a depth of 2 m to analyse the impacts of increasing MSL on extreme surges and wind-waves.ResultsUnder the current scenario, the results indicate that both surges and wave patterns are significantly influenced by seasonal wind patterns. …”
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