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2541
Self-healing of concrete incorporating seashells as partial cement replacement
Published 2025-01-01“…The current experimental study aims to evaluate the effectiveness of a bacteria-based self-healing admixture in low-carbon concrete to minimise maintenance demands on concrete structures. …”
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2542
Everyday living with osteoarthritis in the global South: A qualitative focus group inquiry in Nigeria
Published 2025-03-01“…This study aimed to explore lived experiences, expressed needs and current care gaps for people living with osteoarthritis in low-health resource contexts using Nigeria as a case study. …”
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2543
Application of Cord Blood–Derived Exosomes in Tumor Prevention and Treatment
Published 2025-08-01“…This narrative review examines the current application status of CB-derived EXOs in tumor prevention and treatment: in the context of tumor treatment, it focuses on their direct therapeutic application and their use as drug carriers; regarding tumor prevention, it explores their application in cancer vaccines. …”
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2544
Advancements in textile techniques for cardiovascular tissue replacement and repair
Published 2024-12-01“…However, an acute shortage of organ donors increases waiting times of patients, which is reflected in negative effects on the outcome for the patient. …”
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2545
OPTIMIZATION OF IMID-BASED THERAPIES
Published 2024-12-01“…In this case, it is clear that multiple myeloma treatment optimization cannot be achieved by considering multiple myeloma treatment only as applying the appropriate drug combination.In order to ensure the optimization of IMID-based therapies, it is necessary to take a broad perspective.This perspective should include the correct selection of the patient to be treated with IMID, the development and implementation of IMID forms that will increase patient compliance, the use of techniques to predict the development of resistance, side effect management during treatment, preventing the increase in disease burden with appropriate maneuvers by following the disease burden after treatment, and drug-free follow-up.It is recommended to avoid thalidomide in the presence of peripheral neuropathy, to prefer other agents instead of lenalidomide in the presence of renal function loss, and to avoid pomalidomide in patients with COPD.Nex-20, a once-monthly subcutaneous formulation of lenalidomide, is expected to be an important breakthrough in improving patient compliance.Prediction of which patients will develop resistance will be very useful in order to have the best treatment outcomes.Calculation of miRNA risk scores, measurement of lenalidomide metabolite levels in urine, measurement of cereblon levels in blood, or immunohistochemical detection of cereblon levels are some of the methods currently being tried to predict disease resistance.Patients who develop anemia should be treated with erythropoietin, skin reactions should be treated with steroids and antihistamines, diarrhea should be treated with loperamide and colestyramine, and in general, the drug should be discontinued and the same dose or a lower dose should be insisted upon.An important part of treatment is maintenance therapy with lenalidomide. …”
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2546
Co-regulation and synteny of GFM2 and NSA2 links ribosomal function in mitochondria and the cytosol with chronic kidney disease
Published 2024-10-01“…Their common 381 bp 5’ region contained multiple transcription factor binding sites (TFBS) including the zinc-responsive transcription factor MTF1. …”
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2547
Advances and challenges in the production and use of native bacteria as plant probiotics in agronomic applications: A Mexican review
Published 2025-06-01“…This review addresses key research questions: 1) What is the historical context and current status of biofertilizer use in Mexico? …”
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2548
Clinical Leadership and Integration of Triple Bottom Line for Planetary Health
Published 2023-07-01“…The healthcare community, clinicians, and hospital management are well-placed to play a vital role as change agents with Health in All Policies approach by protecting health during the current climate crises. An eco-friendly, equitable, interprofessional, and transdisciplinary approach is required to create a resilient healthcare sector that works harmoniously with nature while coping with increasing disease burdens and challenges to healthcare infrastructure. …”
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2549
Leishmaniasis in Greece: Prospects of transitioning to a One Health surveillance system
Published 2024-12-01“…Conversely, the existing CanL surveillance governance and the lack of systematic entomological surveillance constitute important drawbacks. Moreover, the current context of public health and animal health financial constraints in Greece may impede a strategic OH transition in leishmaniasis surveillance. …”
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2550
Model-based analysis of the impact of an eco-scheme premium on the climate protection potential of short rotation coppice in Baden-Württemberg
Published 2025-04-01“…Our findings suggested that increasing the premium to €400 ha−1 yr−1 could offset up to 1.5% of the current agricultural GHG emissions of BW. …”
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2551
Correlation of Calibration Parameters for HPGe Detector Efficiency Based on Monte Carlo Simulation
Published 2025-03-01“…High-purity germanium (HPGe) detectors are commonly employed in this context due to their superior characteristics, including high energy resolution, high detection efficiency, and a broad detection range. …”
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2552
Simulation of Spatial and Temporal Patterns of Suitable Wintering Habitat for Hooded Crane (<i>Grus monacha</i>) Under Climate and Land Use Change Scenarios
Published 2024-12-01“…In the context of global warming and intensified human activities, the loss and fragmentation of species habitats have been exacerbated. …”
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2553
Integrated meta-analysis and network pharmacology analysis: evaluation of Zhigancao decoction as treatment for diabetic cardiomyopathy
Published 2025-03-01“…Additionally, the utilization of ZGCD was leading to a reduction in LVEDV, LVESV and LVDD, also a greater increase in LVEF. Meanwhile, the utilization of ZGCD during intervention was more effective in reducing SBP, and DBP. …”
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2554
La transferencia y difusión del conocimiento en el entrenamiento deportivo: una revisión de alcance (The transfer and dissemination of knowledge in sports training: a scoping revie...
Published 2023-09-01“…Objective. To establish the current state of knowledge transfer and diffusion in sports training. …”
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2555
Does use of domestic insecticides undermine public health control strategies?
Published 2025-05-01“…Current research has predominantly examined resistance development in the context of public health interventions and agricultural applications. …”
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2556
Comparison of Grammar Characteristics of Human-Written Corpora and Machine-Generated Texts Using a Novel Rule-Based Parser
Published 2025-03-01“…As the prevalence of machine-written texts grows, it has become increasingly important to distinguish between human- and machine-generated content, especially when such texts are not explicitly labeled. …”
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2557
Valorising mango, cashew apple, and papaya by-products for sustainable small ruminant production in low-income food deficit countries—a review
Published 2025-04-01“…It emphasizes the need for further research to determine their nutritional value in local contexts, establish optimal inclusion levels, and devise strategies for prolonging shelf life. …”
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2558
Deterioration of sleep and mental health in individuals with insomnia during South Africa’s COVID-19 lockdown
Published 2025-05-01“…These findings suggest that these individuals either identify with an insomnia identity or are vulnerable to sleep and mental health difficulties in stressful contexts. …”
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2559
Interior Point Algorithm in Multi-objective Portfolio Optimization: GlueVaR Approach
Published 2023-09-01“…Such algorithms are extensively employed for solving real-world problems, particularly in financial contexts. The major objective of this research is to apply the inner point mathematical algorithm to optimize the stock portfolio and to use this algorithm to address the multi-objective portfolio optimization problem. …”
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2560
Manganese for Whom? A Review on Manganese Mining Permits towards the Existence of Springs’ Sacred Forest in Manggarai Flores
Published 2025-03-01“…Both the spatial analysis and qualitative data are then analyzed alongside the legal framework of land use and spring used to distill the institutional barriers leading to the issuance of permits in such contexts. The analysis then briefly traces the current political economy of mining’s permits underlying the institutional interactions to better understand why the institutions behave as they do. …”
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