Hypoxia-inducible factor-1α promotes tubulointerstitial fibrosis via the upregulation of Muc4 by Zhong-Tang Li, Xin-Hui Hu, Wei-Jie Ni, Zuo-Lin Li, Bi-Kun Huang, Yu Zhang, A-Feng Miao, Jing-Yuan Cao

“…Furthermore, MUC4 overexpression in the context of HIF-1α knockout was positively correlated with increased ECM protein expression and TIF. …”
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Benefit or Coercion: the Perception of Compulsory Service Programs by Doctors Who Are Employed on the Periphery by Ekaterina Aleksandrovna Sharepina, Aleksandra Konstantinovna Lomanova

“…The article also analyzes how these types influence the professional practices of veterinary specialists and considers them in the context of evidence-based medicine and its current development. …”
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Retrospective Study on Ganglionic and Nerve Block Series as Therapeutic Option for Chronic Pain Patients with Refractory Neuropathic Pain by J. D. Gerken, T. Fritzsche, C. Denke, M. Schäfer, S. Tafelski

“…Objective. Current recommendations controversially discuss local infiltration techniques as specific treatment for refractory pain syndromes. …”
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Informed consent in genetic and genomic studies in Sub-Saharan Africa: a systematic review of bioethical issues by Yunqi Li, Deborah J. Bowen, Joon-Ho Yu

“…However, it remains unclear how well the current practices address the full range of informed consent challenges encountered by the stakeholders. …”
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Prevalence Characteristics and Spatial Aggregation of Sudden Cardiac Death in Shandong Province by Counties and Districts, 2020 to 2021 by Yalin Zhou, Bingyin Zhang, Binghang Li, Danru Liu, Chunxiao Xu, Zilong Lu, Xiaolei Guo, Jixiang Ma

“…Given the lack of large‐scale comprehensive studies on the epidemiologic features and spatial clustering of SCD in general populations, particularly in the context of cardiovascular and cerebrovascular events in China, this study aims to enrich the evidence base by analyzing its current situation in Shandong Province. …”
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Important issues of professional burnout among hematologists and hematology department nursing staff during the COVID-19 pandemic by O. A. Aleshina, T. P. Nikitina, N. M. Porfirieva, D. E. Vybornykh, E. N. Parovichnikova, T. I. Ionova

“…Professional burnout (PB) among medical staff, namely hematologists, is of major importance, especially given the current shortage of personnel. It is of extreme value during the COVID-19 pandemic.Aim. …”
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Assessing Patterns and Risk to Chilean Freshwater Fish Distributions Using Multi‐Species Occupancy Models by Erin E. Tracy, Evelyn Habit, Konrad Górski, Nann A. Fangue, Andrew L. Rypel

“…Finally, to put our results in the context of the rapid development in hydropower taking place throughout Chile, we analyzed predicted species richness and occupancy patterns in relation to aquatic ecosystem fragmentation risk from current and planned dams throughout Chile. …”
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The impact of extended reality cognitive behavioral therapy on mental disorders among children and youth: A systematic review and meta-analysis protocol. by Madeline Li, Jamin Patel, Tarun Reddy Katapally

“…<h4>Background</h4>The prevalence of mental disorders among children and youth has significantly increased, with rising rates of anxiety, depression, and other psychological disorders globally. …”
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Environmental disclosure analysis of manufacturing companies to realize sustainable green economy by Avi Sunani, Ulfa Puspa Wanti Widodo, R. Muh. Syah Arief Atmaja Wijaya, Nanda Wahyu Indah Kirana

“…Businesses that adopt socially and sustainably responsible business practices are likely to see improvements in their financial performance as well as increased credibility and confidence from important stakeholders. …”
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QUANTITATIVE APPRAISAL AND SCIENTOMETRIC EXPLORATION INTO THE DIGITIZATION OF EDUCATION by Farhad Rahmanov, Lala Neymatova, Albina Hashimova, Taleh Aghazada

“…A dynamic analysis of research articles showed their intensive growth since 2020, which is due to increased attention to digital education in the context of global transformations, the COVID-19 pandemic, and military conflicts. …”
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Effectiveness of Case Management for 'At Risk' Patients in Primary Care: A Systematic Review and Meta-Analysis. by Jonathan Stokes, Maria Panagioti, Rahul Alam, Kath Checkland, Sudeh Cheraghi-Sohi, Peter Bower

“…Secondary subgroup analyses suggested the effectiveness of case management may be increased when delivered by a multidisciplinary team, when a social worker was involved, and when delivered in a setting rated as low in initial 'strength' of primary care.…”
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The Role of Higher Education Through the Eyes of Hungarian Undergraduate Students and Graduates: A Qualitative Exploratory Study by Zsófia Kocsis, Gabriella Pusztai

“… Context: Most education systems equip graduates with the professional knowledge and cognitive skills needed to enter the world of work. …”
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Robotic-assisted colorectal surgery in colorectal cancer management: a narrative review of clinical efficacy and multidisciplinary integration by Engeng Chen, Li Chen, Wei Zhang

“…This review provides a critical appraisal of the current landscape of RACS, emphasizing its superiority over conventional open and laparoscopic approaches. …”
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Enhanced differentiation between 3‐hydroxyglutaric and 2‐hydroxyglutaric acids facilitates diagnostic testing for glutaric aciduria type 1 by Denis Cyr, Michel Boutin, Bruno Maranda, Paula J. Waters

“…Accurate quantitation of urinary 3‐HG is crucial in diagnostic workup for GA1, but in this context, current gas chromatography–mass spectrometry (GC–MS) methods have inherent analytical challenges. …”
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Advanced Machine Learning and Deep Learning Approaches for Estimating the Remaining Life of EV Batteries—A Review by Daniel H. de la Iglesia, Carlos Chinchilla Corbacho, Jorge Zakour Dib, Vidal Alonso-Secades, Alfonso J. López Rivero

“…While recent years have seen increased adoption of DL methods, the effectiveness of different approaches varies significantly based on application context and data characteristics. …”
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Impacts of CACNB4 overexpression on dendritic spine density in both sexes and relevance to schizophrenia by Emily M. Parker, Nathan L. Kindja, Rebecca A. DeGiosio, Ryan B. Salisbury, Josh M. Krivinko, Claire E. J. Cheetham, Matthew L. MacDonald, Weijia Fan, Bin Cheng, Robert A. Sweet

“…Overexpressing the gene that encodes the voltage-gated calcium channel subunit β4, CACNB4, selectively reduced small spine density in vitro. In the current study we extended this observation in an intact mammalian system within a relevant neurodevelopmental context. …”
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RDAU-Net: A U-Shaped Semantic Segmentation Network for Buildings near Rivers and Lakes Based on a Fusion Approach by Yipeng Wang, Dongmei Wang, Teng Xu, Yifan Shi, Wenguang Liang, Yihong Wang, George P. Petropoulos, Yansong Bao

“…The encroachment of buildings into the waters of rivers and lakes can lead to increased safety hazards, but current semantic segmentation algorithms have difficulty accurately segmenting buildings in such environments. …”
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Combating crime in the sphere of justice: effectiveness of punishment by Mikhail P. Kleymenov, Evgeniy S. Ivanov

“…Criminal liability for insulting a public officer is anachronism in the context of full or partial decriminalization of insults in general (art. 130 of the Russian Criminal Code) and beatings (art. 116 of the Russian Criminal Code).Conclusion. …”
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Detection of reproductive and hematobiochemical biomarkers to evaluate the impact of heavy metal exposure on brick kiln workers by Kibria Hassan, Muhammad Kashif Khan, Mehwish David, Sarwat Jahan, Tayyaba Afsar, Fohad Mabood Husain, Huma Shafique, Suhail Razak

“…Abstract The brick manufacturing process contributes to the presence of heavy metals, particularly in the microenvironment surrounding the kilns. The current study aimed to investigate the effects of heavy metal-containing brick kiln emissions on the reproductive health and hematobiochemical parameters of brick kiln workers in Layyah, Pakistan. …”
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Recent approaches for developing a novel generation of batteries using cement-based materials by Mai Thi Thu Thuy, Nguyen Minh Hai, Nguyen Van Quang, Nguyen Duc Tuan, Tran Dinh Minh, Nguyen Duc Hung

“…In the context of the increasing global demand for sustainable energy development, the solution of using cement-based materials to develop batteries for energy storage has enormous potential, but this topic is still quite new to engineers and scientists in the construction industry. …”
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